Donna Spiegelman, ScD

Susan Dwight Bliss Professor of Biostatistics; Director, Center for Methods in Implementation and Prevention Science (CMIPS); Director, Interdisciplinary Research Methods Core, Center for Interdisciplinary Research on AIDS; Assistant Director, Global Oncology, Yale Cancer Center

Research Departments & Organizations

School of Public Health: Center for Methods in Implementation and Prevention Science (CMIPS) | YSPH Global Health Concentration

Yale Cancer Center: Cancer Prevention and Control

Yale Institute for Global Health

Research Interests

Clinical Trial; Epidemiologic Methods; Global Health; Health Plan Implementation; HIV Infections; Obesity

Research Summary

Donna Spiegelman focuses on implementation science and methods for study design and data analysis which reduce bias in estimation and inference due to measurement error or misclassification in the exposure variable. She has extensive experience in troubleshooting and solving methodological issues that arise in longitudinal investigations, in clinical trials, and in large scale public health effectiveness evaluations. 


  • Measurement Errors in Cancer Epidemiology Jerusalem, Israel (2010 - 2011)

    As cancer epidemiology studies incorporate sophisticated new techniques for exposure measurement, sound statistical approaches to risk estimation and modeling will become increasingly important. The long-term objective of this research is to improve the understanding of cancer etiology and...

  • Measurement Errors in Environmental Epidemiology Amsterdam, Netherlands; Jerusalem, Israel (2009 - 2013)

    Exposure measurement error is a likely source of bias in nearly all environmental and epidemiological studies, typically leading to under-estimation of relative risks and loss of statistical power to detect effects. In the previous cycle of this project, the regression calibration method for...

  • Therapeutic Ultrasound: Biophysical Mechanisms at the Molecular Level Jerusalem, Israel (2006 - 2008)

    In the last decades, low intensity therapeutic ultrasound (TUS) has shown to have a significant effect on cells (modulation of NO production in vivo), tissue (modulation of vessel wall permeability) and organs (angiogenesis or bone healing). To the best of our knowledge, there is no consensus on...

Selected Publications

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