David J Leffell, MD

David P. Smith Professor of Dermatology and Professor of Surgery (Otolaryngology and Plastic); Section Chief, Dermatologic Surgery and Cutaneous Oncology

Research Departments & Organizations

Dermatology: Dermatologic Surgery

Plastic & Reconstructive Surgery

Cancer Genetics

Yale Cancer Center: Genomics, Genetics, and Epigenetics

Research Interests

Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Epidermis; Genes, p53; Head and Neck Neoplasms; Mohs Surgery; Skin Neoplasms

Research Summary

Dr. Leffell and colleagues discovered the skin cancer gene, PTCH, in 1996 and have directed subsequent research towards understanding how skin cancer develops. Other research includes studies of the p53 gene in skin cancer, epidemiology of skin cancer, and innovative diagnostic devices.

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