Chris Cotsapas, PhD

Associate Professor of Neurology; Associate Professor of Genetics

Research Departments & Organizations

Neurology: Nowak Lab

Diabetes Research Center

Human and Translational Immunology Program

Office of Cooperative Research

Research Interests

Arthritis, Rheumatoid; Autoimmune Diseases; Autoimmune Diseases of the Nervous System; Computational Biology; Demyelinating Autoimmune Diseases, CNS; Diabetes Mellitus, Type 1; Genetic Research; Genetics; Genetics, Medical; Genetics, Population; Genomics; Graves Disease; Human Genome Project; Immune System Diseases; Inflammatory Bowel Diseases; Lupus Erythematosus, Systemic; Multiple Sclerosis; Systems Biology; Thyroiditis, Autoimmune

Research Summary

We look for genetic factors that predispose to disease and try to understand the biology they perturb. We ask what genes are perturbed, what processes they participate in and whether these perturbations are sufficient to induce differences at the molecular and cellular levels.This gives us novel targets for biomarkers, diagnosis and treatment.

Our approach encompasses statistical and computational tools, genetics and molecular biology. We are a hybrid lab with strong quantitative and experimental skills and we cycle between hypotheses generated by rigorous analysis and confirmation and discovery in experimental systems.

Selected Publications

See list of PubMed publications

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