Research Departments & Organizations
Connecticut Mental Health Center: Division of Substance Abuse
Smoking Cessation and Alcohol Treatment Research Clinic
Dr. Toll conducts smoking cessation studies aimed at developing novel treatments (both counseling and drug treatments). He is currently testing treatments that emphasize the positive aspects of quitting smoking (e.g., quitting will add years to your life) and interventions aimed at reducing alcohol use amongst smokers who drink at hazardous levels. He is also conducting research aimed at improving the quality of measures of cigarette consumption (e.g., IVR) and smoking related syndromes (e.g., withdrawal).
Specialized Terms: Smoking cessation clinical trials; Quitline studies; Smoking cessation with cancer patients; Secondary analyses of clinical trial data; Analyses of mediators and moderators of treatment; Assessment, methods, and psychometrics
Extensive Research Description
Dr. Toll’s primary research interest involves developing novel psychosocial and pharmacological treatments for tobacco use disorders. Current studies focus on message framing to promote smoking cessation. He has been working with the New York State Smokers' Quitline on studies testing gain-framed counseling (e.g., if you quit smoking you will live longer) and mediators and moderators of responses to gain-framed counseling. He has also been working on studies of naltrexone for minimization of post smoking cessation weight gain. In addition, Dr. Toll is involved in several studies of psychometrics, assessment, and methodological issues with addictive behaviors.
- “Promoting Tobacco and Cancer Control: Message Framing for Telephone Quitline Callers” This project will be a secondary analysis of our New York State Smokers’ Quitline data.
- “Smoking Cessation to Improve Survival Rates of Head and Neck Cancer Patients” This project is an 8-week, open label clinical trial comparing smoking cessation treatment with varenicline 2 mg to nicotine patch 21 mg in a sample of 30 patients who completed treatment for head and neck cancer.
|Lung||Personalized Prevention: Smoking Cessation in Patients With a Lung Nodule|
Tobacco quitlines need to assess and intervene with callers' hazardous drinking.
Toll BA, Cummings KM, O'Malley SS, Carlin-Menter S, McKee SA, Hyland A, Wu R, Hopkins J, Celestino P. Tobacco quitlines need to assess and intervene with callers' hazardous drinking. Alcoholism, Clinical And Experimental Research 2012, 36:1653-8. 2012
Randomized trial: Quitline specialist training in gain-framed vs standard-care messages for smoking cessation.
Toll BA, Martino S, Latimer A, Salovey P, O'Malley S, Carlin-Menter S, Hopkins J, Wu R, Celestino P, Cummings KM. Randomized trial: Quitline specialist training in gain-framed vs standard-care messages for smoking cessation. Journal Of The National Cancer Institute 2010, 102:96-106. 2010
Low-dose naltrexone augmentation of nicotine replacement for smoking cessation with reduced weight gain: a randomized trial.
Toll BA, White M, Wu R, Meandzija B, Jatlow P, Makuch R, O'Malley SS. Low-dose naltrexone augmentation of nicotine replacement for smoking cessation with reduced weight gain: a randomized trial. Drug And Alcohol Dependence 2010, 111:200-6. 2010
A preliminary investigation of naltrexone augmentation of bupropion to stop smoking with less weight gain.
Toll BA, Leary V, Wu R, Salovey P, Meandzija B, O'Malley SS. A preliminary investigation of naltrexone augmentation of bupropion to stop smoking with less weight gain. Addictive Behaviors 2008, 33:173-9. 2008
Comparing gain- and loss-framed messages for smoking cessation with sustained-release bupropion: a randomized controlled trial.
Toll BA, O'Malley SS, Katulak NA, Wu R, Dubin JA, Latimer A, Meandzija B, George TP, Jatlow P, Cooney JL, Salovey P. Comparing gain- and loss-framed messages for smoking cessation with sustained-release bupropion: a randomized controlled trial. Psychology Of Addictive Behaviors : Journal Of The Society Of Psychologists In Addictive Behaviors 2007, 21:534-44. 2007