Zhongwu Liu, MD
Research Scientist
Research & Publications
Biography
News
Research Summary
Cellular Electrophysiology and Neuroscience
Coauthors
Selected Publications
- Direct evidence for wake-related increases and sleep-related decreases in synaptic strength in rodent cortex.Liu ZW, Faraguna U, Cirelli C, Tononi G, Gao XB. Direct evidence for wake-related increases and sleep-related decreases in synaptic strength in rodent cortex. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience 2010, 30: 8671-5. PMID: 20573912, PMCID: PMC2903226, DOI: 10.1523/JNEUROSCI.1409-10.2010.
- UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals.Andrews ZB, Liu ZW, Walllingford N, Erion DM, Borok E, Friedman JM, Tschöp MH, Shanabrough M, Cline G, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S. UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals. Nature 2008, 454: 846-51. PMID: 18668043, PMCID: PMC4101536, DOI: 10.1038/nature07181.
- Intracellular energy status regulates activity in hypocretin/orexin neurones: a link between energy and behavioural states.Liu ZW, Gan G, Suyama S, Gao XB. Intracellular energy status regulates activity in hypocretin/orexin neurones: a link between energy and behavioural states. The Journal Of Physiology 2011, 589: 4157-66. PMID: 21727218, PMCID: PMC3180576, DOI: 10.1113/jphysiol.2011.212514.
- Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity.Diano S, Liu ZW, Jeong JK, Dietrich MO, Ruan HB, Kim E, Suyama S, Kelly K, Gyengesi E, Arbiser JL, Belsham DD, Sarruf DA, Schwartz MW, Bennett AM, Shanabrough M, Mobbs CV, Yang X, Gao XB, Horvath TL. Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity. Nature Medicine 2011, 17: 1121-7. PMID: 21873987, PMCID: PMC3388795, DOI: 10.1038/nm.2421.
- Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity.Dietrich MO, Liu ZW, Horvath TL. Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity. Cell 2013, 155: 188-99. PMID: 24074868, PMCID: PMC4142434, DOI: 10.1016/j.cell.2013.09.004.
- Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite.Abizaid A, Liu ZW, Andrews ZB, Shanabrough M, Borok E, Elsworth JD, Roth RH, Sleeman MW, Picciotto MR, Tschöp MH, Gao XB, Horvath TL. Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite. The Journal Of Clinical Investigation 2006, 116: 3229-39. PMID: 17060947, PMCID: PMC1618869, DOI: 10.1172/JCI29867.
- Characterization of a hyperpolarization-activated inward current in cultured pacemaker cells from the sinoatrial node.Liu ZW, Zou AR, Demir SS, Clark JW, Nathan RD. Characterization of a hyperpolarization-activated inward current in cultured pacemaker cells from the sinoatrial node. Journal Of Molecular And Cellular Cardiology 1996, 28: 2523-35. PMID: 9004168, DOI: 10.1006/jmcc.1996.0244.
- A Neural Circuit for Gut-Induced Reward.Han W, Tellez LA, Perkins MH, Perez IO, Qu T, Ferreira J, Ferreira TL, Quinn D, Liu ZW, Gao XB, Kaelberer MM, Bohórquez DV, Shammah-Lagnado SJ, de Lartigue G, de Araujo IE. A Neural Circuit for Gut-Induced Reward. Cell 2018, 175: 665-678.e23. PMID: 30245012, PMCID: PMC6195474, DOI: 10.1016/j.cell.2018.08.049.
- Impaired hypocretin/orexin system alters responses to salient stimuli in obese male mice.Tan Y, Hang F, Liu ZW, Stoiljkovic M, Wu M, Tu Y, Han W, Lee AM, Kelley C, Hajos M, Lu L, de Lecea L, de Araujo I, Picciotto M, Horvath TL, Gao XB. Impaired hypocretin/orexin system alters responses to salient stimuli in obese male mice. The Journal Of Clinical Investigation 2020, 130: 4985-4998. PMID: 32516139, PMCID: PMC7456212, DOI: 10.1172/JCI130889.
- MC4R Signaling in Dorsal Raphe Nucleus Controls Feeding, Anxiety, and Depression.Bruschetta G, Jin S, Liu ZW, Kim JD, Diano S. MC4R Signaling in Dorsal Raphe Nucleus Controls Feeding, Anxiety, and Depression. Cell Reports 2020, 33: 108267. PMID: 33053350, DOI: 10.1016/j.celrep.2020.108267.