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Zachary Corbin, MD, MHS

Assistant Professor; Director, Neuro-Oncology Fellowship Program, Neurology

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Zachary Corbin, MD, MHS

Research Summary

Dr. Corbin's overarching research goal is to combine neuroimaging and cancer biology to improve both the quality of life and longevity of patients suffering from neuro-oncologic disease.

Extensive Research Description

His clinical research career began as a medical student at Yale, and he then earned a student research fellowship to study at the Massachusetts General Hospital. He trained as a neurologist at the University of California, San Francisco and then completed Neuro-Oncology Fellowship at Stanford University. At Stanford, he led a study employing positron emission tomography (PET)/MRI in patients with glioblastoma who received bevacizumab.

He was recruited back to Yale to develop the program in metabolic imaging in neuro-oncology. With his colleagues at the Yale Magnetic Resonance Research Center, he has deployed deuterium metabolic imaging (DMI) in patients with primary brain tumors. He has since developed a multi-modality imaging technique using PET and magnetic resonance spectroscopy (MRS) called the Warburg Index. He and his colleagues aim to measure metabolic changes in gliomas with a particular mutation in isocitrate dehydrogenase (IDH).

Research Interests

Brain; Brain Neoplasms; Metabolism

Clinical Trials