Yury M. Morozov, PhD
Research Scientist in Neuroscience
Research & Publications
Biography
News
Research Summary
My current research is
focused on the development of cerebral interneurons. I determined site and
timing of origin and migratory routes of prospective cannabinoid type 1
receptor containing interneurons. I demonstrated that neurochemical properties
and fate of this interneuronal subgroup, similar to the projection neurons, are
determined at the time and place of last cell division (Cerebral Cortex, 2009). I demonstrated for the first time translocation
of synaptically interconnected basket interneurons in the postnatal rat
hippocampus what may occur in response to local functional demand and
represents a novel mode of cell movement and form of neuroplasticity (J. Neurosci., 2006).
Coauthors
Research Interests
Central Nervous System; Neurodegenerative Diseases
Research Images
Selected Publications
- Antibodies to cannabinoid type 1 receptor co-react with stomatin-like protein 2 in mouse brain mitochondria.Morozov YM, Dominguez MH, Varela L, Shanabrough M, Koch M, Horvath TL, Rakic P. Antibodies to cannabinoid type 1 receptor co-react with stomatin-like protein 2 in mouse brain mitochondria. The European Journal Of Neuroscience 2013, 38: 2341-8. PMID: 23617247, PMCID: PMC3902808, DOI: 10.1111/ejn.12237.
- Origin, early commitment, migratory routes, and destination of cannabinoid type 1 receptor-containing interneurons.Morozov YM, Torii M, Rakic P. Origin, early commitment, migratory routes, and destination of cannabinoid type 1 receptor-containing interneurons. Cerebral Cortex (New York, N.Y. : 1991) 2009, 19 Suppl 1: i78-89. PMID: 19346272, PMCID: PMC3584650, DOI: 10.1093/cercor/bhp028.
- Hardwiring the brain: endocannabinoids shape neuronal connectivity.Berghuis P, Rajnicek AM, Morozov YM, Ross RA, Mulder J, Urbán GM, Monory K, Marsicano G, Matteoli M, Canty A, Irving AJ, Katona I, Yanagawa Y, Rakic P, Lutz B, Mackie K, Harkany T. Hardwiring the brain: endocannabinoids shape neuronal connectivity. Science (New York, N.Y.) 2007, 316: 1212-6. PMID: 17525344, DOI: 10.1126/science.1137406.
- Translocation of synaptically connected interneurons across the dentate gyrus of the early postnatal rat hippocampus.Morozov YM, Ayoub AE, Rakic P. Translocation of synaptically connected interneurons across the dentate gyrus of the early postnatal rat hippocampus. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience 2006, 26: 5017-27. PMID: 16687493, PMCID: PMC6674251, DOI: 10.1523/JNEUROSCI.0272-06.2006.
- Altering cannabinoid signaling during development disrupts neuronal activity.Bernard C, Milh M, Morozov YM, Ben-Ari Y, Freund TF, Gozlan H. Altering cannabinoid signaling during development disrupts neuronal activity. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 9388-93. PMID: 15964987, PMCID: PMC1166590, DOI: 10.1073/pnas.0409641102.
- Post-natal development of type 1 cannabinoid receptor immunoreactivity in the rat hippocampus.Morozov YM, Freund TF. Post-natal development of type 1 cannabinoid receptor immunoreactivity in the rat hippocampus. The European Journal Of Neuroscience 2003, 18: 1213-22. PMID: 12956720.