Yuhong Lu, PhD, MD
Associate Research Scientist in Therapeutic Radiology
Research & Publications
Biography
News
Coauthors
Selected Publications
- Abstract 1877: Hypoxia induces EGFR inhibitor resistance in lung cancer cells by upregulation of fibroblast growth factor receptor 1 (FGFR1) via MAPK pathwayLu Y, Liu Y, Oeck S, Zhang G, Glazer P. Abstract 1877: Hypoxia induces EGFR inhibitor resistance in lung cancer cells by upregulation of fibroblast growth factor receptor 1 (FGFR1) via MAPK pathway. Cancer Research 2020, 80: 1877-1877. DOI: 10.1158/1538-7445.am2020-1877.
- Regulation of DNA Repair by HypoxiaLu Y, Glazer P. Regulation of DNA Repair by Hypoxia. 2016, 169-188. DOI: 10.1142/9789813147324_0007.
- Abstract 2887: Epigenetic silencing of the DNA repair genes, BRCA1 and MLH1, induced by hypoxic stress in a pathway dependent on the histone demethylase, LSD1Lu Y, Chu A, Wajapeyee N, Turker M, Glazer P. Abstract 2887: Epigenetic silencing of the DNA repair genes, BRCA1 and MLH1, induced by hypoxic stress in a pathway dependent on the histone demethylase, LSD1. 2015, 2887-2887. DOI: 10.1158/1538-7445.am2015-2887.
- Abstract 1513: MLH1 silencing is caused by hypoxia through epigenetic regulation..Lu Y, Wajapeyee N, Turker M, Glazer P. Abstract 1513: MLH1 silencing is caused by hypoxia through epigenetic regulation.. Cancer Research 2013, 73: 1513-1513. DOI: 10.1158/1538-7445.am2013-1513.
- Hypoxia-Induced Epigenetic Regulation and Silencing of the BRCA1 PromoterLu Y, Chu A, Turker MS, Glazer PM. Hypoxia-Induced Epigenetic Regulation and Silencing of the BRCA1 Promoter. Molecular And Cellular Biology 2011, 31: 3339-3350. PMID: 21670155, PMCID: PMC3147797, DOI: 10.1128/mcb.01121-10.
- Abstract 1969: Inhibition of poly(ADP-ribose) polymerase downregulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130Hegan D, Lu Y, Stachelek G, Crosby M, Bindra R, Glazer P. Abstract 1969: Inhibition of poly(ADP-ribose) polymerase downregulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130. Cancer Research 2010, 70: 1969-1969. DOI: 10.1158/1538-7445.am10-1969.
- Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130Hegan DC, Lu Y, Stachelek GC, Crosby ME, Bindra RS, Glazer PM. Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 2201-2206. PMID: 20133863, PMCID: PMC2836641, DOI: 10.1073/pnas.0904783107.
- Molecular mechanisms underlying IGF-I-induced attenuation of the growth-inhibitory activity of trastuzumab (Herceptin) on SKBR3 breast cancer cells.Lu Y, Zi X, Pollak M. Molecular mechanisms underlying IGF-I-induced attenuation of the growth-inhibitory activity of trastuzumab (Herceptin) on SKBR3 breast cancer cells. International Journal Of Cancer. Journal International Du Cancer 2004, 108: 334-41. PMID: 14648698, DOI: 10.1002/ijc.11445.
- Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells.Lu Y, Zi X, Zhao Y, Pollak M. Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells. Biochemical And Biophysical Research Communications 2004, 313: 709-15. PMID: 14697248.
- Co-targeting HER2/ErbB2 and insulin-like growth factor-1 receptors causes synergistic inhibition of growth in HER2-overexpressing breast cancer cells.Camirand A, Lu Y, Pollak M. Co-targeting HER2/ErbB2 and insulin-like growth factor-1 receptors causes synergistic inhibition of growth in HER2-overexpressing breast cancer cells. Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research 2002, 8: BR521-6. PMID: 12503030.
- Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin).Lu Y, Zi X, Zhao Y, Mascarenhas D, Pollak M. Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). Journal Of The National Cancer Institute 2001, 93: 1852-7. PMID: 11752009.