Research & Publications
The entire focus of our research is to evaluate improved ways to treat children and adolescents with diabetes and related disorders such as childhood obesity. These studies span the spectrum of clinical research from testing of advances in diabetes technology directed at the development of an artificial pancreas to behavoral interventions aimed at improved outcomes with current therapies and clinical trials of new drugs for treatment of adolescents with type 2 diabetes. Our center has been at the forefront of pediatric diabetes research for many years. Indeed, over the past 15 years, our clinical research in diabetes is an important reason why Pediatric Endocrinology is the only Yale New-Haven Hospital program that has been consistently ranked as one of the top 10 sections in its field in the annual US News and World Report Hospital surveys.
Specialized Terms: Advances in the treatment of type 1 and 2 diabetes; Counterregulatory Hormone Responses to Hypoglycemia; Psychosocial Consequences of Diabetes; Behavioral Interventions in Diabetes; insulin pumps; continuous glucose monitoring; artificial pancreas development
Extensive Research Description
Dr. William Tamborlane studies diabetes and metabolism in children. He directs the Yale Center in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study and is the Principal Investigator in the Yale Center in the NIH-supported, multi-center GRADE study of type 2 diabetes. Dr. Tamborlane is Co-Program Director of the Combined Adult and Pediatric training grant in endocrinology/diabetes from the NIH/NIDDK, as well as Program Director of the Yale Pediatric Diabetes Career Development K12 program from NIH/NIDDK . He is Deputy Director of the Yale Center for Clinical Investigation that is transforming the support that is provided for clinical research across the entire medical center campus and the Director of the Translational Science Core of the Yale Diabetes Research Center. In April 2006 he received the prestigious Mary Tyler Moore and S. Robert Levine Excellence in Clinical Research Award from the Juvenile Diabetes Research Foundation International at its annual meeting in Washington, D.C. In 2009 Dr. Tamborlane received the Diabetes Technology Society Leadership Award, in 2010 the American Diabetes Association Outstanding Clinician Physician in Diabetes Award, in 2014 he received the Career Achievement Award from the International Society for Pediatric and Adolescent Diabetes (ISPAD) and in 2017 he received the American Diabetes Association Award for Achievements in Clinical Diabetes Research. He is the author or co-author of more than 1,000 publications in diabetes and related disorders.
- continuous glucose monitoring studies
- insulin pump studies
- artificial pancreas studies
- pharmacokinetic and pharmacodynamic studies
- hypoglycemia studies
- pivotal trials for new drugs for youth with T2D and T1D
Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glucose; Hypoglycemia; Insulin; Pediatrics; Pancreas, Artificial