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William Asch, MD/PhD, BA

Associate Professor of Medicine (Nephrology); Program Director, Transplant Nephrology Fellowship Program, Internal Medicine; Director of Pre-Transplant Operations, Internal Medicine

Contact Information

William Asch, MD/PhD, BA

Office Location

Mailing Address

  • Nephrology

    PO Box 208029

    New Haven, CT 06520-8029

    United States

Yale Medicine

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Coauthors

Selected Publications

  • Cloning of zebrafish vsx1: expression of a paired-like homeobox gene during CNS development.Passini MA, Kurtzman AL, Canger AK, Asch WS, Wray GA, Raymond PA, Schechter N. Cloning of zebrafish vsx1: expression of a paired-like homeobox gene during CNS development. Developmental Genetics 1998, 23: 128-41. PMID: 9770270, DOI: 10.1002/(SICI)1520-6408(1998)23:2<128::AID-DVG5>3.0.CO;2-8.
  • Restricted expression of the neuronal intermediate filament protein plasticin during zebrafish development.Canger AK, Passini MA, Asch WS, Leake D, Zafonte BT, Glasgow E, Schechter N. Restricted expression of the neuronal intermediate filament protein plasticin during zebrafish development. The Journal Of Comparative Neurology 1998, 399: 561-72. PMID: 9741483, DOI: 10.1002/(sici)1096-9861(19981005)399:4<561::aid-cne8>3.0.co;2-#.
  • Cloning of zebrafish neurofilament cDNAs for plasticin and gefiltin: increased mRNA expression in ganglion cells after optic nerve injury.Asch WS, Leake D, Canger AK, Passini MA, Argenton F, Schechter N. Cloning of zebrafish neurofilament cDNAs for plasticin and gefiltin: increased mRNA expression in ganglion cells after optic nerve injury. Journal Of Neurochemistry 1998, 71: 20-32. PMID: 9648847, DOI: 10.1046/j.1471-4159.1998.71010020.x.
  • Gefiltin in zebrafish embryos: sequential gene expression of two neurofilament proteins in retinal ganglion cells.Leake D, Asch WS, Canger AK, Schechter N. Gefiltin in zebrafish embryos: sequential gene expression of two neurofilament proteins in retinal ganglion cells. Differentiation; Research In Biological Diversity 1999, 65: 181-9. PMID: 10653354, DOI: 10.1046/j.1432-0436.1999.6540181.x.
  • Plasticin, a type III neuronal intermediate filament protein, assembles as an obligate heteropolymer: implications for axonal flexibility.Asch WS, Schechter N. Plasticin, a type III neuronal intermediate filament protein, assembles as an obligate heteropolymer: implications for axonal flexibility. Journal Of Neurochemistry 2000, 75: 1475-86. PMID: 10987827, DOI: 10.1046/j.1471-4159.2000.0751475.x.
  • Kidney transplantation and HIV: does recipient privacy outweigh the donor's right to information?Formica RN, Asch WS, Wagner KR, Kulkarni S. Kidney transplantation and HIV: does recipient privacy outweigh the donor's right to information? Clinical Journal Of The American Society Of Nephrology : CJASN 2010, 5: 924-8. PMID: 20203162, PMCID: PMC2863980, DOI: 10.2215/CJN.06820909.
  • Should living kidney donor candidates with impaired fasting glucose donate?Vigneault CB, Asch WS, Dahl NK, Bia MJ. Should living kidney donor candidates with impaired fasting glucose donate? Clinical Journal Of The American Society Of Nephrology : CJASN 2011, 6: 2054-9. PMID: 21784837, DOI: 10.2215/CJN.03370411.
  • Combined liver kidney transplantation: critical analysis of a single-center experience.Cimsit B, Schilsky M, Moini M, Cartiera K, Arvelakis A, Kulkarni S, Formica R, Caldwell C, Taddei T, Asch W, Emre S. Combined liver kidney transplantation: critical analysis of a single-center experience. Transplantation Proceedings 2011, 43: 901-4. PMID: 21486624, DOI: 10.1016/j.transproceed.2011.02.033.
  • When should nephrectomy be performed for a failed renal transplant?Asch WS, Bia M. When should nephrectomy be performed for a failed renal transplant? Seminars In Dialysis 2011, 24: 374-6. PMID: 21801221, DOI: 10.1111/j.1525-139X.2011.00903.x.
  • Multidetector CT angiography in living donor renal transplantation: accuracy and discrepancies in right venous anatomy.Kulkarni S, Emre S, Arvelakis A, Asch W, Bia M, Formica R, Israel G. Multidetector CT angiography in living donor renal transplantation: accuracy and discrepancies in right venous anatomy. Clinical Transplantation 2011, 25: 77-82. PMID: 20070320, DOI: 10.1111/j.1399-0012.2009.01193.x.
  • A one-day centralized work-up for kidney transplant recipient candidates: a quality improvement report.Formica RN, Barrantes F, Asch WS, Bia MJ, Coca S, Kalyesubula R, McCloskey B, Leary T, Arvelakis A, Kulkarni S. A one-day centralized work-up for kidney transplant recipient candidates: a quality improvement report. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2012, 60: 288-94. PMID: 22571868, DOI: 10.1053/j.ajkd.2012.04.008.
  • Patient education to reduce disparities in renal transplantation.Asch WS, Bia MJ. Patient education to reduce disparities in renal transplantation. Clinical Journal Of The American Society Of Nephrology : CJASN 2012, 7: 527-9. PMID: 22403275, DOI: 10.2215/CJN.01770212.
  • Oncologic issues and kidney transplantation: a review of frequency, mortality, and screening.Asch WS, Bia MJ. Oncologic issues and kidney transplantation: a review of frequency, mortality, and screening. Advances In Chronic Kidney Disease 2014, 21: 106-13. PMID: 24359993, DOI: 10.1053/j.ackd.2013.07.003.
  • Duration of prophylaxis against fungal infection in kidney transplant recipients.Guerra CM, Formica RN, Kulkarni S, Asch WS, Tichy EM. Duration of prophylaxis against fungal infection in kidney transplant recipients. Progress In Transplantation (Aliso Viejo, Calif.) 2015, 25: 311-5. PMID: 26645924, DOI: 10.7182/pit2015929.
  • Revision of immunosuppression in a solid organ transplant recipient leads to complete remission of metastatic undifferentiated carcinoma.Waldman AH, McNiff JM, Liapakis A, Asch WS, Smith-Marrone S, Colegio OR. Revision of immunosuppression in a solid organ transplant recipient leads to complete remission of metastatic undifferentiated carcinoma. JAAD Case Reports 2015, 1: S8-S11. PMID: 27051810, PMCID: PMC4809581, DOI: 10.1016/j.jdcr.2015.09.010.
  • Renal cancer in kidney transplanted patients.Frascà GM, Sandrini S, Cosmai L, Porta C, Asch W, Santoni M, Salviani C, D'Errico A, Malvi D, Balestra E, Gallieni M. Renal cancer in kidney transplanted patients. Journal Of Nephrology 2015, 28: 659-68. PMID: 26202137, DOI: 10.1007/s40620-015-0219-8.
  • Hyperuricemia and gout in solid-organ transplant: update in pharmacological management.Sullivan PM, William A, Tichy EM. Hyperuricemia and gout in solid-organ transplant: update in pharmacological management. Progress In Transplantation (Aliso Viejo, Calif.) 2015, 25: 263-70. PMID: 26308787, DOI: 10.7182/pit2015322.
  • Belatacept and Eculizumab for Treatment of Calcineurin Inhibitor-induced Thrombotic Microangiopathy After Kidney Transplantation: Case Report.Merola J, Yoo PS, Schaub J, Smith JD, Rodriguez-Davalos MI, Tichy E, Mulligan DC, Asch W, Formica R, Kashgarian M, Kulkarni S. Belatacept and Eculizumab for Treatment of Calcineurin Inhibitor-induced Thrombotic Microangiopathy After Kidney Transplantation: Case Report. Transplantation Proceedings 2016, 48: 3106-3108. PMID: 27932157, DOI: 10.1016/j.transproceed.2016.04.005.
  • Cancer and Mortality in Solid-Organ Transplantation: Preventable or Inevitable?Asch WS, Perazella MA. Cancer and Mortality in Solid-Organ Transplantation: Preventable or Inevitable? American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2016, 68: 839-842. PMID: 27405594, DOI: 10.1053/j.ajkd.2016.06.009.
  • Delayed Graft Function Phenotypes and 12-Month Kidney Transplant Outcomes.Hall IE, Reese PP, Doshi MD, Weng FL, Schröppel B, Asch WS, Ficek J, Thiessen-Philbrook H, Parikh CR. Delayed Graft Function Phenotypes and 12-Month Kidney Transplant Outcomes. Transplantation 2017, 101: 1913-1923. PMID: 27495761, PMCID: PMC5292094, DOI: 10.1097/TP.0000000000001409.
  • New Organ Allocation System for Combined Liver-Kidney Transplants and the Availability of Kidneys for Transplant to Patients with Stage 4-5 CKD.Asch WS, Bia MJ. New Organ Allocation System for Combined Liver-Kidney Transplants and the Availability of Kidneys for Transplant to Patients with Stage 4-5 CKD. Clinical Journal Of The American Society Of Nephrology : CJASN 2017, 12: 848-852. PMID: 28028050, PMCID: PMC5477211, DOI: 10.2215/CJN.08480816.
  • New England BK consortium: Regional survey of BK screening and management protocols in comparison to published consensus guidelines.Gabardi S, Pavlakis M, Tan C, Francis J, Cardarelli F, Asch W, Bodziak K, Chobanian M, Gilligan H, Gohh R, Kung SC, Inker L, Martin S, Rodig N, Rossi A, Chandraker A. New England BK consortium: Regional survey of BK screening and management protocols in comparison to published consensus guidelines. Transplant Infectious Disease : An Official Journal Of The Transplantation Society 2018, 20: e12985. PMID: 30175491, DOI: 10.1111/tid.12985.
  • Is Hypertension Following Donor Nephrectomy Cause For Elevated Living Donor Kidney Function Concern?Asch WS. Is Hypertension Following Donor Nephrectomy Cause For Elevated Living Donor Kidney Function Concern? Clinical Journal Of The American Society Of Nephrology : CJASN 2019, 14: 1427-1429. PMID: 31591256, PMCID: PMC6777590, DOI: 10.2215/CJN.09650819.
  • Graft-Versus-Host Disease After Pancreatic Transplantation.Saffo S, Peng C, Kibbi N, Patel N, Robert ME, Adekolu E, Asch WS, Sanchez M. Graft-Versus-Host Disease After Pancreatic Transplantation. ACG Case Reports Journal 2019, 6: e00214. PMID: 31750381, PMCID: PMC6831153, DOI: 10.14309/crj.0000000000000214.
  • The Role of the General Nephrologist in Evaluating Patients for Kidney Transplantation: Core Curriculum 2020.Virmani S, Asch WS. The Role of the General Nephrologist in Evaluating Patients for Kidney Transplantation: Core Curriculum 2020. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2020, 76: 567-579. PMID: 32199707, DOI: 10.1053/j.ajkd.2020.01.001.
  • Clinical Implications of Unique Drug Interaction Between Extended Release Tacrolimus and Phenytoin.Harkness TM, Cohen EA, Asch WS, Belfield KD. Clinical Implications of Unique Drug Interaction Between Extended Release Tacrolimus and Phenytoin. Progress In Transplantation (Aliso Viejo, Calif.) 2020, 30: 177-178. PMID: 32233829, DOI: 10.1177/1526924820913500.
  • Identifying a Kidney Transplant Recipient COVID Phenotype to Aid Test Utilization in the Setting of Limited Testing Availability-Does One Exist?Virmani S, Gleeson SE, Girone GF, Malhotra D, Cohen EA, Klarman SE, Asch WS. Identifying a Kidney Transplant Recipient COVID Phenotype to Aid Test Utilization in the Setting of Limited Testing Availability-Does One Exist? Transplantation Proceedings 2020, 52: 2584-2591. PMID: 32711848, PMCID: PMC7305913, DOI: 10.1016/j.transproceed.2020.05.033.
  • Impact of Low-Dose Fluconazole on Tacrolimus Dosing in Renal Transplant.Johnston JP, Cohen EA, Casal GH, Asch WS, Reardon DP. Impact of Low-Dose Fluconazole on Tacrolimus Dosing in Renal Transplant. Journal Of Pharmacy Practice 2021, 8971900211000702. PMID: 33759619, DOI: 10.1177/08971900211000702.
  • Genetic and Epidemiologic Analyses of an Outbreak of Pneumocystis jirovecii Pneumonia Among Kidney Transplant Recipients in the United States.Azar MM, Cohen E, Ma L, Cissé OH, Gan G, Deng Y, Belfield K, Asch W, Grant M, Gleeson S, Koff A, Gaston DC, Topal J, Curran S, Kulkarni S, Kovacs JA, Malinis M. Genetic and Epidemiologic Analyses of an Outbreak of Pneumocystis jirovecii Pneumonia Among Kidney Transplant Recipients in the United States. Clinical Infectious Diseases : An Official Publication Of The Infectious Diseases Society Of America 2022, 74: 639-647. PMID: 34017984, PMCID: PMC9012955, DOI: 10.1093/cid/ciab474.
  • Ambulatory blood pressure in patients with chronic kidney disease.21. Asch WS, Santos SFF, Peixoto AJ. Ambulatory blood pressure in patients with chronic kidney disease. In Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics, Clinical Hypertension and Vascular Diseases. Ed. William B. White. Humana Press Inc., New York, NY. 2015.
  • Kidney Transplantation24. Nemr, Saed, and Asch, WS. "Kidney Transplantation." In: CURRENT Diagnosis & Treatment: Nephrology & Hypertension, 2e Eds. Edgar V. Lerma, et al. New York, NY: McGraw-Hill. 2017
  • Molecular genetics of magnesium homeostasis.Asch, W.S. and Lifton R.P. Molecular genetics of magnesium homeostasis. In Genetic Diseases of the Kidney Eds. R.P Lifton, S. Somlo, G. Giebisch, & D. Seldin. Elsevier/Academic Press, San Diego, CA. 2009 pp. 249-261
  • Evaluating the Impact and Rationale of Race-Specific Estimations of Kidney Function: Estimations from U.S. NHANES, 2015-2018.Tsai JW, Cerdeña JP, Goedel WC, Asch WS, Grubbs V, Mendu ML, Kaufman JS. Evaluating the Impact and Rationale of Race-Specific Estimations of Kidney Function: Estimations from U.S. NHANES, 2015-2018. EClinicalMedicine 2021, 42: 101197. PMID: 34849475, PMCID: PMC8608882, DOI: 10.1016/j.eclinm.2021.101197.
  • Blood transcriptomes of SARS-CoV-2 infected kidney transplant recipients demonstrate immune insufficiency.Sun Z, Zhang Z, Banu K, Azzi YA, Reghuvaran A, Fredericks S, Planoutene M, Hartzell S, Pell J, Tietjen G, Asch W, Kulkarni S, Formica R, Rana M, Zhang W, Akalin E, Cravedi P, Heeger PS, Menon MC. Blood transcriptomes of SARS-CoV-2 infected kidney transplant recipients demonstrate immune insufficiency. MedRxiv : The Preprint Server For Health Sciences 2022 PMID: 35132424, PMCID: PMC8820676, DOI: 10.1101/2022.01.31.22270203.
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