Wenliang Zhou, PhD
Associate Research Scientist in Psychiatry
Research & Publications
Biography
News
Coauthors
Selected Publications
- Activity of a direct VTA to ventral pallidum GABA pathway encodes unconditioned reward value and sustains motivation for rewardZhou WL, Kim K, Ali F, Pittenger ST, Calarco CA, Mineur YS, Ramakrishnan C, Deisseroth K, Kwan AC, Picciotto MR. Activity of a direct VTA to ventral pallidum GABA pathway encodes unconditioned reward value and sustains motivation for reward. Science Advances 2022, 8: eabm5217. PMID: 36260661, PMCID: PMC9581470, DOI: 10.1126/sciadv.abm5217.
- Hippocampal acetylcholine modulates stress-related behaviors independent of specific cholinergic inputsMineur YS, Mose TN, Vanopdenbosch L, Etherington IM, Ogbejesi C, Islam A, Pineda CM, Crouse RB, Zhou W, Thompson DC, Bentham MP, Picciotto MR. Hippocampal acetylcholine modulates stress-related behaviors independent of specific cholinergic inputs. Molecular Psychiatry 2022, 27: 1829-1838. PMID: 34997190, PMCID: PMC9106825, DOI: 10.1038/s41380-021-01404-7.
- Local glutamate-mediated dendritic plateau potentials change the state of the cortical pyramidal neuronGao PP, Graham JW, Zhou WL, Jang J, Angulo S, Dura-Bernal S, Hines M, Lytton WW, Antic SD. Local glutamate-mediated dendritic plateau potentials change the state of the cortical pyramidal neuron. Journal Of Neurophysiology 2020, 125: 23-42. PMID: 33085562, PMCID: PMC8087381, DOI: 10.1152/jn.00734.2019.
- Molecular and cellular characterization of nicotinic acetylcholine receptor subtypes in the arcuate nucleus of the mouse hypothalamusCalarco CA, Li Z, Taylor SR, Lee S, Zhou W, Friedman JM, Mineur YS, Gotti C, Picciotto MR. Molecular and cellular characterization of nicotinic acetylcholine receptor subtypes in the arcuate nucleus of the mouse hypothalamus. European Journal Of Neuroscience 2018, 48: 1600-1619. PMID: 29791746, PMCID: PMC6251769, DOI: 10.1111/ejn.13966.
- Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neuronsLi D, Musante V, Zhou W, Picciotto MR, Nairn AC. Striatin-1 is a B subunit of protein phosphatase PP2A that regulates dendritic arborization and spine development in striatal neurons. Journal Of Biological Chemistry 2018, 293: 11179-11194. PMID: 29802198, PMCID: PMC6052221, DOI: 10.1074/jbc.ra117.001519.
- The stochastic nature of action potential backpropagation in apical tuft dendritesShort SM, Oikonomou KD, Zhou WL, Acker CD, Popovic MA, Zecevic D, Antic SD. The stochastic nature of action potential backpropagation in apical tuft dendrites. Journal Of Neurophysiology 2017, 118: 1394-1414. PMID: 28566465, PMCID: PMC5558024, DOI: 10.1152/jn.00800.2016.
- Antidepressant-like effects of guanfacine and sex-specific differences in effects on c-fos immunoreactivity and paired-pulse ratio in male and female miceMineur YS, Bentham MP, Zhou WL, Plantenga ME, McKee SA, Picciotto MR. Antidepressant-like effects of guanfacine and sex-specific differences in effects on c-fos immunoreactivity and paired-pulse ratio in male and female mice. Psychopharmacology 2015, 232: 3539-3549. PMID: 26146014, PMCID: PMC4561580, DOI: 10.1007/s00213-015-4001-3.
- Acetylcholine Acts through Nicotinic Receptors to Enhance the Firing Rate of a Subset of Hypocretin Neurons in the Mouse Hypothalamus through Distinct pre- and Postsynaptic MechanismsZhou WL, Gao XB, Picciotto MR. Acetylcholine Acts through Nicotinic Receptors to Enhance the Firing Rate of a Subset of Hypocretin Neurons in the Mouse Hypothalamus through Distinct pre- and Postsynaptic Mechanisms. ENeuro 2015, 2: eneuro.0052-14.2015. PMID: 26322330, PMCID: PMC4551500, DOI: 10.1523/eneuro.0052-14.2015.
- Branch specific and spike-order specific action potential invasion in basal, oblique, and apical dendrites of cortical pyramidal neuronsZhou W, Short S, Rich M, Oikonomou K, Singh M, Sterjanaj E, Antic S. Branch specific and spike-order specific action potential invasion in basal, oblique, and apical dendrites of cortical pyramidal neurons. Neurophotonics 2014, 2: 021006-021006. PMID: 26157997, PMCID: PMC4478750, DOI: 10.1117/1.nph.2.2.021006.
- Connexin hemichannels contribute to spontaneous electrical activity in the human fetal cortexMoore A, Zhou W, Sirois C, Belinsky G, Zecevic N, Antic S. Connexin hemichannels contribute to spontaneous electrical activity in the human fetal cortex. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: e3919-e3928. PMID: 25197082, PMCID: PMC4169969, DOI: 10.1073/pnas.1405253111.
- Palette of fluorinated voltage-sensitive hemicyanine dyesYan P, Acker C, Zhou W, Lee P, Bollensdorff C, Negrean A, Lotti J, Sacconi L, Antic S, Kohl P, Mansvelder H, Pavone F, Loew L. Palette of fluorinated voltage-sensitive hemicyanine dyes. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 20443-20448. PMID: 23169660, PMCID: PMC3528613, DOI: 10.1073/pnas.1214850109.
- Dopaminergic Regulation of Dendritic Calcium: Fast Multisite Calcium ImagingZhou W, Oikonomou K, Short S, Antic S. Dopaminergic Regulation of Dendritic Calcium: Fast Multisite Calcium Imaging. 2012, 964: 123-138. PMID: 23296782, DOI: 10.1007/978-1-62703-251-3_9.
- Physiological Properties of Human Fetal Cortex In VitroMoore A, Zhou W, Jakovcevski I, Zecevic N, Antic S. Physiological Properties of Human Fetal Cortex In Vitro. 2012, 73: 125-158. DOI: 10.1007/978-1-62703-020-5_3.
- Rapid dopaminergic and GABAergic modulation of calcium and voltage transients in dendrites of prefrontal cortex pyramidal neuronsZhou W, Antic S. Rapid dopaminergic and GABAergic modulation of calcium and voltage transients in dendrites of prefrontal cortex pyramidal neurons. The Journal Of Physiology 2012, 590: 3891-3911. PMID: 22641784, PMCID: PMC3476639, DOI: 10.1113/jphysiol.2011.227157.
- Spontaneous Electrical Activity in the Human Fetal Cortex In VitroMoore A, Zhou W, Jakovcevski I, Zecevic N, Antic S. Spontaneous Electrical Activity in the Human Fetal Cortex In Vitro. Journal Of Neuroscience 2011, 31: 2391-2398. PMID: 21325506, PMCID: PMC3564513, DOI: 10.1523/jneurosci.3886-10.2011.
- Brief dopaminergic stimulations produce transient physiological changes in prefrontal pyramidal neuronsMoore A, Zhou W, Potapenko E, Kim E, Antic S. Brief dopaminergic stimulations produce transient physiological changes in prefrontal pyramidal neurons. Brain Research 2010, 1370: 1-15. PMID: 21059342, PMCID: PMC3019254, DOI: 10.1016/j.brainres.2010.10.111.
- The decade of the dendritic NMDA spikeAntic S, Zhou W, Moore A, Short S, Ikonomu K. The decade of the dendritic NMDA spike. Journal Of Neuroscience Research 2010, 88: 2991-3001. PMID: 20544831, PMCID: PMC5643072, DOI: 10.1002/jnr.22444.
- Dynamics of action potential backpropagation in basal dendrites of prefrontal cortical pyramidal neuronsZhou W, Yan P, Wuskell J, Loew L, Antic S. Dynamics of action potential backpropagation in basal dendrites of prefrontal cortical pyramidal neurons. European Journal Of Neuroscience 2008, 27: 923-936. PMID: 18279369, PMCID: PMC2715167, DOI: 10.1111/j.1460-9568.2008.06075.x.
- Voltage and calcium transients in basal dendrites of the rat prefrontal cortexMilojkovic B, Zhou W, Antic S. Voltage and calcium transients in basal dendrites of the rat prefrontal cortex. The Journal Of Physiology 2007, 585: 447-468. PMID: 17932150, PMCID: PMC2375496, DOI: 10.1113/jphysiol.2007.142315.
- Intracellular long-wavelength voltage-sensitive dyes for studying the dynamics of action potentials in axons and thin dendritesZhou W, Yan P, Wuskell J, Loew L, Antic S. Intracellular long-wavelength voltage-sensitive dyes for studying the dynamics of action potentials in axons and thin dendrites. Journal Of Neuroscience Methods 2007, 164: 225-239. PMID: 17560661, PMCID: PMC2001318, DOI: 10.1016/j.jneumeth.2007.05.002.
- A novel artemisinin derivative, 3-(12-β-artemisininoxy) phenoxyl succinic acid (SM735), mediates immunosuppressive effects in vitro and in vivoZhou W, Wu J, Wu Q, Wang J, Zhou Y, Zhou R, He P, Li X, Yang Y, Zhang Y, Li Y, Zuo J. A novel artemisinin derivative, 3-(12-β-artemisininoxy) phenoxyl succinic acid (SM735), mediates immunosuppressive effects in vitro and in vivo. Acta Pharmacologica Sinica 2005, 26: 1352-1358. PMID: 16225758, DOI: 10.1111/j.1745-7254.2005.00232.x.
- (5R)-5-hydroxytriptolide (LLDT-8), a novel triptolide analog mediates immunosuppressive effects in vitro and in vivoZhou R, Zhang F, He P, Zhou W, Wu Q, Xu J, Zhou Y, Tang W, Li X, Yang Y, Li Y, Zuo J. (5R)-5-hydroxytriptolide (LLDT-8), a novel triptolide analog mediates immunosuppressive effects in vitro and in vivo. International Immunopharmacology 2005, 5: 1895-1903. PMID: 16275624, DOI: 10.1016/j.intimp.2005.06.009.
- Synthesis and Immunosuppressive Activity of New Artemisinin Derivatives. 1. [12(β or α)-Dihydroartemisininoxy]phen(ox)yl Aliphatic Acids and EstersYang Z, Zhou W, Sui Y, Wang J, Wu J, Zhou Y, Zhang Y, He P, Han J, Tang W, Li Y, Zuo J. Synthesis and Immunosuppressive Activity of New Artemisinin Derivatives. 1. [12(β or α)-Dihydroartemisininoxy]phen(ox)yl Aliphatic Acids and Esters. Journal Of Medicinal Chemistry 2005, 48: 4608-4617. PMID: 15999998, DOI: 10.1021/jm048979c.
- Inhibition of S-Adenosyl-l-homocysteine Hydrolase Induces ImmunosuppressionWu Q, Fu Y, Zhou W, Wang J, Feng Y, Liu J, Xu J, He P, Zhou R, Tang W, Wang G, Zhou Y, Yang Y, Ding J, Li X, Chen X, Yuan C, Lawson B, Zuo J. Inhibition of S-Adenosyl-l-homocysteine Hydrolase Induces Immunosuppression. Journal Of Pharmacology And Experimental Therapeutics 2005, 313: 705-711. PMID: 15640397, DOI: 10.1124/jpet.104.080416.
- Low dose of resveratrol enhanced immune response of mice.Feng Y, Zhou W, Wu Q, Li X, Zhao W, Zou J. Low dose of resveratrol enhanced immune response of mice. Acta Pharmacologica Sinica 2002, 23: 893-7. PMID: 12370094.