Wade Schulz, MD, PhD

• Aaron Ring
• Adam Wisnewski
• Aditya Biswas
• Akiko Iwasaki
• Albert C Shaw
• Albert Ko
• Aldo Peixoto
• Alexa Siddon
• Allen Hsiao
• Amit Gokhale
• Andreas Coppi
• Anne Wyllie
• Arijit Sehanobish
• Arnar Geirsson
• Avinainder Singh
• Benjamin Goldman-Israelow
• Bobak Jack Mortazavi
• Brian Smith
• Carlos Mena-Hurtado
• Carolina Lucas
• Cesar Caraballo-Cordovez
• Chantal Vogels
• Charles Dela Cruz
• Charles Torre
• Chenxi Huang
• Christopher Tormey
• David Peaper
• David van Dijk
• Dennis Moledina
• Eben Olson
• Edward Snyder
• Eric Velazquez
• Erica Spatz
• F. Perry Wilson
• Frederick Warner
• Harlan Krumholz
• Harvey Kliman
• Henry Rinder
• Jacob M McPadden
• Jason Greenberg
• Jeanne Hendrickson
• Jeffrey Testani
• Joe El-Khoury
• John Fournier
• John Greg Howe
• Jonathan Siner
• Joseph Ross
• Karla M Neugebauer
• Karthik Murugiah
• Katherine Harper Campbell
• Khurram Nasir
• Lama Ghazi
• Lloyd G. Cantley
• Lohith Gowda
• Melissa Campbell
• Merceditas Villanueva
• Michael Chiorazzi
• Michael Simonov
• Monique Hinchcliff
• Murat Gunel
• Nathan Grubaugh
• Neal Ravindra
• Nihar Desai
• Patrick Young
• Peiwen Lu
• Rebecca Ross
• Richard Taylor
• Richard Torres
• Rohan Khera
• Roy S. Herbst
• Ruslan Medzhitov
• Saad B. Omer
• Seth Guller
• Shelli Farhadian
• Sherry Mansour
• Shiwani Mahajan
• Shuangge Steven Ma
• Shu-Xia Li
• Subhasis Mohanty
• Takehiro Takahashi
• Tanima Arora
• Thomas Durant
• Ugochukwu Ugwuowo
• Yongfei Wang
• Yuan Lu
• Zhenqiu Lin

Artificial Intelligence; Blood Transfusion; Clinical Laboratory Information Systems; Medical Informatics Computing; Information Management; Data Mining; Data Warehousing

• Investigation of increased platelet alloimmunization screening in the era of pathogen-reduced platelets treated with psoralen/UV light.Hendrickson JE, Mendoza H, Ross R, Siddon AJ, Gowda L, Hauser RG, Schulz WL, Tormey CA. Investigation of increased platelet alloimmunization screening in the era of pathogen-reduced platelets treated with psoralen/UV light. Transfusion 2020, 60:650-651.
• Blood utilisation and transfusion reactions in adult patients transfused with conventional or pathogen-reduced platelets.Bahar B, Schulz WL, Gokhale A, Spencer BR, Gehrie EA, Snyder EL. Blood utilisation and transfusion reactions in adult patients transfused with conventional or pathogen-reduced platelets. British Journal Of Haematology 2020, 188:465-472.
• Validation and Regulation of Clinical Artificial Intelligence.Schulz WL, Durant TJS, Krumholz HM. Validation and Regulation of Clinical Artificial Intelligence. Clinical Chemistry 2019, 65:1336-1337.
• Tapping Into Underutilized Healthcare Data in Clinical Research.Mori M, Schulz WL, Geirsson A, Krumholz HM. Tapping Into Underutilized Healthcare Data in Clinical Research. Annals Of Surgery 2019, 270:227-229.
• Traditional Chinese Medicine Use in the Treatment of Acute Heart Failure in Western Medicine Hospitals in China: Analysis From the China PEACE Retrospective Heart Failure Study.Yu Y, Spatz ES, Tan Q, Liu S, Lu Y, Masoudi FA, Schulz WL, Krumholz HM, Li J. Traditional Chinese Medicine Use in the Treatment of Acute Heart Failure in Western Medicine Hospitals in China: Analysis From the China PEACE Retrospective Heart Failure Study. Journal Of The American Heart Association 2019, 8:e012776.
• Health Care and Precision Medicine Research: Analysis of a Scalable Data Science Platform.McPadden J, Durant TJ, Bunch DR, Coppi A, Price N, Rodgerson K, Torre CJ, Byron W, Hsiao AL, Krumholz HM, Schulz WL. Health Care and Precision Medicine Research: Analysis of a Scalable Data Science Platform. Journal Of Medical Internet Research 2019, 21:e13043.
• Blood Utilization and Transfusion Reactions in Pediatric Patients Transfused with Conventional or Pathogen Reduced Platelets.Schulz WL, McPadden J, Gehrie EA, Bahar B, Gokhale A, Ross R, Price N, Spencer BR, Snyder E. Blood Utilization and Transfusion Reactions in Pediatric Patients Transfused with Conventional or Pathogen Reduced Platelets. The Journal Of Pediatrics 2019, 209:220-225.
• Characteristics of High Cardiovascular Risk in 1.7 Million Chinese Adults.Lu J, Lu Y, Yang H, Bilige W, Li Y, Schulz W, Masoudi FA, Krumholz HM. Characteristics of High Cardiovascular Risk in 1.7 Million Chinese Adults. Annals Of Internal Medicine 2019, 170:298-308.
• Association of Body Mass Index With Blood Pressure Among 1.7 Million Chinese Adults.Linderman GC, Lu J, Lu Y, Sun X, Xu W, Nasir K, Schulz W, Jiang L, Krumholz HM. Association of Body Mass Index With Blood Pressure Among 1.7 Million Chinese Adults. JAMA Network Open 2018, 1:e181271.
• Prediction of ICU Readmissions Using Data at Patient Discharge.Pakbin A, Rafi P, Hurley N, Schulz W, Harlan Krumholz M, Bobak Mortazavi J. Prediction of ICU Readmissions Using Data at Patient Discharge. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society. IEEE Engineering In Medicine And Biology Society. Annual International Conference 2018, 2018:4932-4935.
• Enhancing the prediction of acute kidney injury risk after percutaneous coronary intervention using machine learning techniques: A retrospective cohort study.Huang C, Murugiah K, Mahajan S, Li SX, Dhruva SS, Haimovich JS, Wang Y, Schulz WL, Testani JM, Wilson FP, Mena CI, Masoudi FA, Rumsfeld JS, Spertus JA, Mortazavi BJ, Krumholz HM. Enhancing the prediction of acute kidney injury risk after percutaneous coronary intervention using machine learning techniques: A retrospective cohort study. PLoS Medicine 2018, 15:e1002703.
• Fulfilling the Promise of Unique Device Identifiers.Dhruva SS, Ross JS, Schulz WL, Krumholz HM. Fulfilling the Promise of Unique Device Identifiers. Annals Of Internal Medicine 2018, 169:183-185.
• A novel network analysis tool to identify relationships between disease states and risks for red blood cell alloimmunization.Celli R, Schulz W, Hendrickson JE, Tormey CA. A novel network analysis tool to identify relationships between disease states and risks for red blood cell alloimmunization. Vox Sanguinis 2017, 112:469-472.
• Moving Averages: Real-Time Data Monitoring in the Clinical Chemistry Laboratory.Durant T, Schulz W, El-Khoury J. Moving Averages: Real-Time Data Monitoring in the Clinical Chemistry Laboratory. American Journal Of Clinical Pathology 2017.
• Blockchain Technology: Applications in Health Care.Angraal S, Krumholz HM, Schulz WL. Blockchain Technology: Applications in Health Care. Circulation. Cardiovascular Quality And Outcomes 2017, 10.
• Very Deep Convolutional Neural Networks for Morphologic Classification of Erythrocytes.Durant TJS, Olson EM, Schulz WL, Torres R. Very Deep Convolutional Neural Networks for Morphologic Classification of Erythrocytes. Clinical Chemistry 2017, 63:1847-1855.
• Use of application containers and workflows for genomic data analysis.Schulz WL, Durant TJ, Siddon AJ, Torres R. Use of application containers and workflows for genomic data analysis. Journal Of Pathology Informatics 2016, 7:53.
• Evaluation of relational and NoSQL database architectures to manage genomic annotations.Schulz WL, Nelson BG, Felker DK, Durant TJ, Torres R. Evaluation of relational and NoSQL database architectures to manage genomic annotations. Journal Of Biomedical Informatics 2016, 64:288-295.
• Computational Approach to Annotating Variants of Unknown Significance in Clinical Next Generation Sequencing.Schulz WL, Tormey CA, Torres R. Computational Approach to Annotating Variants of Unknown Significance in Clinical Next Generation Sequencing. Laboratory Medicine 2015, 46:285-9.
• Reovirus uses multiple endocytic pathways for cell entry.Schulz WL, Haj AK, Schiff LA. Reovirus uses multiple endocytic pathways for cell entry. Journal Of Virology 2012, 86:12665-75.
• Interactions between multiple genetic determinants in the 5' UTR and VP1 capsid control pathogenesis of chronic post-viral myopathy caused by coxsackievirus B1.Sandager MM, Nugent JL, Schulz WL, Messner RP, Tam PE. Interactions between multiple genetic determinants in the 5' UTR and VP1 capsid control pathogenesis of chronic post-viral myopathy caused by coxsackievirus B1. Virology 2008, 372:35-47.
• HOS2 and HDA1 encode histone deacetylases with opposing roles in Candida albicans morphogenesis.Zacchi LF, Schulz WL, Davis DA. HOS2 and HDA1 encode histone deacetylases with opposing roles in Candida albicans morphogenesis. PloS One 2010, 5:e12171.
• A student authored online medical education textbook: editing patterns and content evaluation of a medical student wiki.Thompson CL, Schulz WL, Terrence A. A student authored online medical education textbook: editing patterns and content evaluation of a medical student wiki. AMIA ... Annual Symposium Proceedings / AMIA Symposium. AMIA Symposium 2011, 2011:1392-401.
• Amputation neuroma growing intravascularly into a thrombus.Schulz WL, Manivel JC. Amputation neuroma growing intravascularly into a thrombus. International Journal Of Surgical Pathology 2014, 22:645-6.
• Leveraging the Electronic Health Records for Population Health: A Case Study of Patients With Markedly Elevated Blood Pressure.Lu Y, Huang C, Mahajan S, Schulz WL, Nasir K, Spatz ES, Krumholz HM. Leveraging the Electronic Health Records for Population Health: A Case Study of Patients With Markedly Elevated Blood Pressure. Journal Of The American Heart Association 2020, 9:e015033.
• Agile Health Care Analytics: Enabling Real-Time Disease Surveillance With a Computational Health Platform.Schulz WL, Durant TJ, Torre CJ, Hsiao AL, Krumholz HM. Agile Health Care Analytics: Enabling Real-Time Disease Surveillance With a Computational Health Platform. Journal Of Medical Internet Research 2020, 22:e18707.
• Rates and Predictors of Patient Underreporting of Hospitalizations During Follow-Up After Acute Myocardial Infarction: An Assessment From the TRIUMPH Study.Caraballo C, Khera R, Jones PG, Decker C, Schulz W, Spertus JA, Krumholz HM. Rates and Predictors of Patient Underreporting of Hospitalizations During Follow-Up After Acute Myocardial Infarction: An Assessment From the TRIUMPH Study. Circulation. Cardiovascular Quality And Outcomes 2020, 13:e006231.
• Bridging the Collaboration Gap: Real-time Identification of Clinical Specimens for Biomedical Research.Durant TJS, Gong G, Price N, Schulz WL. Bridging the Collaboration Gap: Real-time Identification of Clinical Specimens for Biomedical Research. Journal Of Pathology Informatics 2020, 11:14.
• Impact of COVID-19 Pandemic on Laboratory Utilization.Durant TJS, Peaper DR, Ferguson D, Schulz WL. Impact of COVID-19 Pandemic on Laboratory Utilization. The Journal Of Applied Laboratory Medicine 2020, 5:1194-1205.
• Longitudinal analyses reveal immunological misfiring in severe COVID-19.Lucas C, Wong P, Klein J, Castro TBR, Silva J, Sundaram M, Ellingson MK, Mao T, Oh JE, Israelow B, Takahashi T, Tokuyama M, Lu P, Venkataraman A, Park A, Mohanty S, Wang H, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Muenker MC, Fournier JB, Campbell M, Odio CD, Casanovas-Massana A, Herbst R, Shaw AC, Medzhitov R, Schulz WL, Grubaugh ND, Dela Cruz C, Farhadian S, Ko AI, Omer SB, Iwasaki A. Longitudinal analyses reveal immunological misfiring in severe COVID-19. Nature 2020, 584:463-469.
• Impact of intra-tumoral heterogeneity detected by next-generation sequencing on acute myeloid leukemia survival.Schulz WL, Rinder HM, Durant TJS, Tormey CA, Torres R, Smith BR, Hager KM, Howe JG, Siddon AJ. Impact of intra-tumoral heterogeneity detected by next-generation sequencing on acute myeloid leukemia survival. Leukemia & Lymphoma 2020, 61:3269-3271.
• Sex differences in immune responses that underlie COVID-19 disease outcomes.Takahashi T, Ellingson MK, Wong P, Israelow B, Lucas C, Klein J, Silva J, Mao T, Oh JE, Tokuyama M, Lu P, Venkataraman A, Park A, Liu F, Meir A, Sun J, Wang EY, Casanovas-Massana A, Wyllie AL, Vogels CBF, Earnest R, Lapidus S, Ott IM, Moore AJ, Shaw A, Fournier JB, Odio CD, Farhadian S, Dela Cruz C, Grubaugh ND, Schulz WL, Ring AM, Ko AI, Omer SB, Iwasaki A. Sex differences in immune responses that underlie COVID-19 disease outcomes. Nature 2020, 588:315-320.
• Clinical Characteristics and Outcomes for 7,995 Patients with SARS-CoV-2 Infection.McPadden J, Warner F, Young HP, Hurley NC, Pulk RA, Singh A, Durant TJ, Gong G, Desai N, Haimovich A, Taylor RA, Gunel M, Dela Cruz CS, Farhadian SF, Siner J, Villanueva M, Churchwell K, Hsiao A, Torre CJ, Velazquez EJ, Herbst RS, Iwasaki A, Ko AI, Mortazavi BJ, Krumholz HM, Schulz WL. Clinical Characteristics and Outcomes for 7,995 Patients with SARS-CoV-2 Infection. MedRxiv : The Preprint Server For Health Sciences 2020.
• Patient factors associated with SARS-CoV-2 in an admitted emergency department population.Haimovich A, Warner F, Young HP, Ravindra NG, Sehanobish A, Gong G, Wilson FP, van Dijk D, Schulz W, Taylor RA. Patient factors associated with SARS-CoV-2 in an admitted emergency department population. Journal Of The American College Of Emergency Physicians Open 2020.
• Agile analytics to support rapid knowledge pipelines.Schulz WL, Kvedar JC, Krumholz HM. Agile analytics to support rapid knowledge pipelines. NPJ Digital Medicine 2020, 3:108.
• Development and Validation of the Quick COVID-19 Severity Index: A Prognostic Tool for Early Clinical Decompensation.Haimovich AD, Ravindra NG, Stoytchev S, Young HP, Wilson FP, van Dijk D, Schulz WL, Taylor RA. Development and Validation of the Quick COVID-19 Severity Index: A Prognostic Tool for Early Clinical Decompensation. Annals Of Emergency Medicine 2020, 76:442-453.
• The Association of COVID-19 With Acute Kidney Injury Independent of Severity of Illness: A Multicenter Cohort Study.Moledina DG, Simonov M, Yamamoto Y, Alausa J, Arora T, Biswas A, Cantley LG, Ghazi L, Greenberg JH, Hinchcliff M, Huang C, Mansour SG, Martin M, Peixoto A, Schulz W, Subair L, Testani JM, Ugwuowo U, Young P, Wilson FP. The Association of COVID-19 With Acute Kidney Injury Independent of Severity of Illness: A Multicenter Cohort Study. American Journal Of Kidney Diseases : The Official Journal Of The National Kidney Foundation 2021, 77:490-499.e1.
• The Promise of Big Data and Digital Solutions in Building a Cardiovascular Learning System: Opportunities and Barriers.Mori M, Khera R, Lin Z, Ross JS, Schulz W, Krumholz HM. The Promise of Big Data and Digital Solutions in Building a Cardiovascular Learning System: Opportunities and Barriers. Methodist DeBakey Cardiovascular Journal 2020, 16:212-219.
• Evaluation of a Risk Stratification Model Using Preoperative and Intraoperative Data for Major Morbidity or Mortality After Cardiac Surgical Treatment.Durant TJS, Jean RA, Huang C, Coppi A, Schulz WL, Geirsson A, Krumholz HM. Evaluation of a Risk Stratification Model Using Preoperative and Intraoperative Data for Major Morbidity or Mortality After Cardiac Surgical Treatment. JAMA Network Open 2020, 3:e2028361.
• Agile analytics to support rapid knowledge pipelines.Schulz WL, Kvedar JC, Krumholz HM. Agile analytics to support rapid knowledge pipelines. NPJ Digital Medicine 2020, 3:108.
• Temporal relationship of computed and structured diagnoses in electronic health record data.Schulz WL, Young HP, Coppi A, Mortazavi BJ, Lin Z, Jean RA, Krumholz HM. Temporal relationship of computed and structured diagnoses in electronic health record data. BMC Medical Informatics And Decision Making 2021, 21:61.
• Diverse Functional Autoantibodies in Patients with COVID-19.Wang EY, Mao T, Klein J, Dai Y, Huck JD, Liu F, Zheng NS, Zhou T, Israelow B, Wong P, Lucas C, Silva J, Oh JE, Song E, Perotti ES, Fischer S, Campbell M, Fournier JB, Wyllie AL, Vogels CBF, Ott IM, Kalinich CC, Petrone ME, Watkins AE, Cruz CD, Farhadian SF, Schulz WL, Grubaugh ND, Ko AI, Iwasaki A, Ring AM. Diverse Functional Autoantibodies in Patients with COVID-19. MedRxiv : The Preprint Server For Health Sciences 2020.
• Kinetics of antibody responses dictate COVID-19 outcome.Lucas C, Klein J, Sundaram M, Liu F, Wong P, Silva J, Mao T, Oh JE, Tokuyama M, Lu P, Venkataraman A, Park A, Israelow B, Wyllie AL, Vogels CBF, Muenker MC, Casanovas-Massana A, Schulz WL, Zell J, Campbell M, Fournier JB, Grubaugh ND, Farhadian S, Wisnewski AV, Cruz CD, Omer S, Ko AI, Ring A, Iwasaki A. Kinetics of antibody responses dictate COVID-19 outcome. MedRxiv : The Preprint Server For Health Sciences 2020.
• Saliva viral load is a dynamic unifying correlate of COVID-19 severity and mortality.Silva J, Lucas C, Sundaram M, Israelow B, Wong P, Klein J, Tokuyama M, Lu P, Venkataraman A, Liu F, Mao T, Oh JE, Park A, Casanovas-Massana A, Vogels CBF, Muenker CM, Zell J, Fournier JB, Campbell M, Chiorazzi M, Ruiz Fuentes E, Petrone M, Kalinich CC, Ott IM, Watkins A, Moore AJ, Nakahata MI, Grubaugh ND, Farhadian S, Dela Cruz C, Ko A, Schulz WL, Ring AM, Ma S, Omer S, Wyllie AL, Iwasaki A. Saliva viral load is a dynamic unifying correlate of COVID-19 severity and mortality. MedRxiv : The Preprint Server For Health Sciences 2021.
• SARS-CoV-2 infection in pregnancy is associated with robust inflammatory response at the maternal-fetal interface.Lu-Culligan A, Chavan AR, Vijayakumar P, Irshaid L, Courchaine EM, Milano KM, Tang Z, Pope SD, Song E, Vogels CBF, Lu-Culligan WJ, Campbell KH, Casanovas-Massana A, Bermejo S, Toothaker JM, Lee HJ, Liu F, Schulz W, Fournier J, Muenker MC, Moore AJ, Konnikova L, Neugebauer KM, Ring A, Grubaugh ND, Ko AI, Morotti R, Guller S, Kliman HJ, Iwasaki A, Farhadian SF. SARS-CoV-2 infection in pregnancy is associated with robust inflammatory response at the maternal-fetal interface. MedRxiv : The Preprint Server For Health Sciences 2021.
• Clinical characteristics and outcomes for 7,995 patients with SARS-CoV-2 infection.McPadden J, Warner F, Young HP, Hurley NC, Pulk RA, Singh A, Durant TJS, Gong G, Desai N, Haimovich A, Taylor RA, Gunel M, Dela Cruz CS, Farhadian SF, Siner J, Villanueva M, Churchwell K, Hsiao A, Torre CJ, Velazquez EJ, Herbst RS, Iwasaki A, Ko AI, Mortazavi BJ, Krumholz HM, Schulz WL. Clinical characteristics and outcomes for 7,995 patients with SARS-CoV-2 infection. PloS One 2021, 16:e0243291.
• Longitudinal Assessment of SARS-CoV-2 Anti-Nucleocapsid and anti-Spike-1-RBD Antibody Testing Following PCR-Detected SARS-CoV-2 Infection.El-Khoury JM, Schulz WL, Durant TJS. Longitudinal Assessment of SARS-CoV-2 Anti-Nucleocapsid and anti-Spike-1-RBD Antibody Testing Following PCR-Detected SARS-CoV-2 Infection. The Journal Of Applied Laboratory Medicine 2021.