Tormod Rogne, MD, PhD
Assistant Professor of Epidemiology (Chronic Diseases)
Research & Publications
Biography
News
Research Summary
Dr. Rogne's research prior to starting his tenure-track at Yale can be divided in two: His PhD was in traditional perinatal epidemiology, while genetic epidemiology of infectious diseases was the focus during his postdoctoral fellowship. As Assistant Professor of Perinatal Epidemiology Dr. Rogne will combine these experiences to study genetic epidemiology in the perinatal setting. This will include to study the maternal and offspring genetic effect of birth outcomes, and also implementing genetic variants in an instrumental variable analysis framework (often referred to as Mendelian randomization) as a technique to come closer to the causal effect of an exposure on an outcome. The nationwide Nordic registries and the Norwegian Mother, Father and Child Cohort Study are currently his primary sources of data, but he aims to include data from the U.S. in the future.
Coauthors
Research Interests
Environmental Health; Genetics; Pregnancy; Prenatal Care; Reproduction; Global Health; Perinatal Care; Genomics; Child Health
Public Health Interests
Environmental Health; Genetics, Genomics, Epigenetics; Global Health; Infectious Diseases; Maternal & Child Health; Reproduction; Perinatal/Prenatal Health
Selected Publications
- GWAS Identifies LINC01184/SLC12A2 as a Risk Locus for Skin and Soft Tissue Infections.Rogne T, Liyanarachi KV, Rasheed H, Thomas LF, Flatby HM, Stenvik J, Løset M, Gill D, Burgess S, Willer CJ, Hveem K, Åsvold BO, Brumpton BM, DeWan AT, Solligård E, Damås JK. GWAS Identifies LINC01184/SLC12A2 as a Risk Locus for Skin and Soft Tissue Infections. The Journal Of Investigative Dermatology 2021, 141: 2083-2086.e8. PMID: 33662382, DOI: 10.1016/j.jid.2021.01.020.
- The Role of FER rs4957796 in the Risk of Developing and Dying from a Bloodstream Infection: A 23-Year Follow-up of the Population-based Nord-Trøndelag Health Study.Rogne T, Damås JK, Flatby HM, Åsvold BO, DeWan AT, Solligård E. The Role of FER rs4957796 in the Risk of Developing and Dying from a Bloodstream Infection: A 23-Year Follow-up of the Population-based Nord-Trøndelag Health Study. Clinical Infectious Diseases : An Official Publication Of The Infectious Diseases Society Of America 2021, 73: e297-e303. PMID: 32699877, PMCID: PMC8282309, DOI: 10.1093/cid/ciaa786.
- Relationship Between Blood Pressure and Incident Cardiovascular Disease: Linear and Nonlinear Mendelian Randomization Analyses.Malik R, Georgakis MK, Vujkovic M, Damrauer SM, Elliott P, Karhunen V, Giontella A, Fava C, Hellwege JN, Shuey MM, Edwards TL, Rogne T, Åsvold BO, Brumpton BM, Burgess S, Dichgans M, Gill D. Relationship Between Blood Pressure and Incident Cardiovascular Disease: Linear and Nonlinear Mendelian Randomization Analyses. Hypertension 2021, 77: 2004-2013. PMID: 33813844, PMCID: PMC8115430, DOI: 10.1161/HYPERTENSIONAHA.120.16534.
- Genome-Wide Linkage Analysis of the Risk of Contracting a Bloodstream Infection in 47 Pedigrees Followed for 23 Years Assembled From a Population-Based Cohort (the HUNT Study).Rogne T, Damås JK, Solligård E, DeWan AT. Genome-Wide Linkage Analysis of the Risk of Contracting a Bloodstream Infection in 47 Pedigrees Followed for 23 Years Assembled From a Population-Based Cohort (the HUNT Study). Critical Care Medicine 2020, 48: 1580-1586. PMID: 32885941, DOI: 10.1097/CCM.0000000000004520.
- Body mass index and risk of dying from a bloodstream infection: A Mendelian randomization study.Rogne T, Solligård E, Burgess S, Brumpton BM, Paulsen J, Prescott HC, Mohus RM, Gustad LT, Mehl A, Åsvold BO, DeWan AT, Damås JK. Body mass index and risk of dying from a bloodstream infection: A Mendelian randomization study. PLoS Medicine 2020, 17: e1003413. PMID: 33196656, PMCID: PMC7668585, DOI: 10.1371/journal.pmed.1003413.
- Cardiometabolic Traits, Sepsis, and Severe COVID-19: A Mendelian Randomization Investigation.Ponsford MJ, Gkatzionis A, Walker VM, Grant AJ, Wootton RE, Moore LSP, Fatumo S, Mason AM, Zuber V, Willer C, Rasheed H, Brumpton B, Hveem K, Kristian Damås J, Davies N, Åsvold BO, Solligård E, Jones S, Burgess S, Rogne T, Gill D. Cardiometabolic Traits, Sepsis, and Severe COVID-19: A Mendelian Randomization Investigation. Circulation 2020, 142: 1791-1793. PMID: 32966752, PMCID: PMC7594537, DOI: 10.1161/CIRCULATIONAHA.120.050753.
- Pediatric Patients in a Local Nepali Emergency Department: Presenting Complaints, Triage and Post-Discharge Mortality.Giri S, Halvas-Svendsen T, Rogne T, Shrestha SK, Døllner H, Solligård E, Risnes K. Pediatric Patients in a Local Nepali Emergency Department: Presenting Complaints, Triage and Post-Discharge Mortality. Global Pediatric Health 2020, 7: 2333794X20947926. PMID: 32995370, PMCID: PMC7502999, DOI: 10.1177/2333794X20947926.
- Rate of avoidable deaths in a Norwegian hospital trust as judged by retrospective chart review.Rogne T, Nordseth T, Marhaug G, Berg EM, Tromsdal A, Sæther O, Gisvold S, Hatlen P, Hogan H, Solligård E. Rate of avoidable deaths in a Norwegian hospital trust as judged by retrospective chart review. BMJ Quality & Safety 2019, 28: 49-55. PMID: 30026281, DOI: 10.1136/bmjqs-2018-008053.
- Presenting complaints and mortality in a cohort of 22 000 adult emergency patients at a local hospital in Nepal.Giri S, Rogne T, Uleberg O, Skovlund E, Shrestha SK, Koju R, Damås JK, Solligård E, Risnes KR. Presenting complaints and mortality in a cohort of 22 000 adult emergency patients at a local hospital in Nepal. Journal Of Global Health 2019, 9: 020403. PMID: 31489186, PMCID: PMC6708590, DOI: 10.7189/jogh.09.020403.
- Impact of 2015 earthquakes on a local hospital in Nepal: A prospective hospital-based study.Giri S, Risnes K, Uleberg O, Rogne T, Shrestha SK, Nygaard ØP, Koju R, Solligård E. Impact of 2015 earthquakes on a local hospital in Nepal: A prospective hospital-based study. PloS One 2018, 13: e0192076. PMID: 29394265, PMCID: PMC5796718, DOI: 10.1371/journal.pone.0192076.
- Associations of Maternal Vitamin B12 Concentration in Pregnancy With the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data.Rogne T, Tielemans MJ, Chong MF, Yajnik CS, Krishnaveni GV, Poston L, Jaddoe VW, Steegers EA, Joshi S, Chong YS, Godfrey KM, Yap F, Yahyaoui R, Thomas T, Hay G, Hogeveen M, Demir A, Saravanan P, Skovlund E, Martinussen MP, Jacobsen GW, Franco OH, Bracken MB, Risnes KR. Associations of Maternal Vitamin B12 Concentration in Pregnancy With the Risks of Preterm Birth and Low Birth Weight: A Systematic Review and Meta-Analysis of Individual Participant Data. American Journal Of Epidemiology 2017, 185: 212-223. PMID: 28108470, PMCID: PMC5390862, DOI: 10.1093/aje/kww212.
- Fetal growth, cognitive function, and brain volumes in childhood and adolescence.Rogne T, Engstrøm AA, Jacobsen GW, Skranes J, Østgård HF, Martinussen M. Fetal growth, cognitive function, and brain volumes in childhood and adolescence. Obstetrics And Gynecology 2015, 125: 673-682. PMID: 25730232, DOI: 10.1097/AOG.0000000000000694.
- Association between low blood glucose increase during glucose tolerance tests in pregnancy and impaired fetal growth.Rogne T, Jacobsen GW. Association between low blood glucose increase during glucose tolerance tests in pregnancy and impaired fetal growth. Acta Obstetricia Et Gynecologica Scandinavica 2014, 93: 1160-9. PMID: 24576054, DOI: 10.1111/aogs.12365.
- Epidemiological and clinical characteristics of immunocompromised patients infected with Pneumocystis jirovecii in a twelve-year retrospective study from Norway.Grønseth S, Rogne T, Hannula R, Åsvold BO, Afset JE, Damås JK. Epidemiological and clinical characteristics of immunocompromised patients infected with Pneumocystis jirovecii in a twelve-year retrospective study from Norway. BMC Infectious Diseases 2021, 21: 659. PMID: 34233631, PMCID: PMC8262122, DOI: 10.1186/s12879-021-06144-1.
- Semiquantitative Real-Time PCR to Distinguish Pneumocystis Pneumonia from Colonization in a Heterogeneous Population of HIV-Negative Immunocompromised Patients.Grønseth S, Rogne T, Hannula R, Åsvold BO, Afset JE, Damås JK. Semiquantitative Real-Time PCR to Distinguish Pneumocystis Pneumonia from Colonization in a Heterogeneous Population of HIV-Negative Immunocompromised Patients. Microbiology Spectrum 2021, 9: e0002621. PMID: 34346746, PMCID: PMC8552647, DOI: 10.1128/Spectrum.00026-21.
- Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study.Hernáez Á, Rogne T, Skåra KH, Håberg SE, Page CM, Fraser A, Burgess S, Lawlor DA, Magnus MC. Body mass index and subfertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study. Human Reproduction (Oxford, England) 2021, 36: 3141-3151. PMID: 34668019, PMCID: PMC8600658, DOI: 10.1093/humrep/deab224.
- Liten ved fødselen – årsaker og konsekvenser.Rogne T. Liten ved fødselen – årsaker og konsekvenser. Tidsskrift For Den Norske Lægeforening : Tidsskrift For Praktisk Medicin, Ny Række 2017, 137: 746. PMID: 28551982, DOI: 10.4045/tidsskr.17.0098.
- Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations.Flatby HM, Rasheed H, Ravi A, Thomas LF, Liyanarachi KV, Afset JE, DeWan AT, Brumpton BM, Hveem K, Åsvold BO, Simonsen GS, Furberg AS, Damås JK, Solligård E, Rogne T. Risk of lower respiratory tract infections: a genome-wide association study with Mendelian randomization analysis in three independent European populations. Clinical Microbiology And Infection : The Official Publication Of The European Society Of Clinical Microbiology And Infectious Diseases 2022, 28: 732.e1-732.e7. PMID: 34763054, DOI: 10.1016/j.cmi.2021.11.004.
- Systemic iron status and maternal pregnancy complications: a Mendelian randomization study.Rogne T, Burgess S, Gill D. Systemic iron status and maternal pregnancy complications: a Mendelian randomization study. International Journal Of Epidemiology 2022, 51: 1024-1027. PMID: 35234877, DOI: 10.1093/ije/dyac037.
- Modifiable Risk Factors for Ectopic Pregnancy: A Mendelian Randomization Study.Rogne T, Liew Z, Hernáez Á, Brumpton BM, Magnus MC. Modifiable Risk Factors for Ectopic Pregnancy: A Mendelian Randomization Study. American Journal Of Obstetrics And Gynecology 2022 PMID: 35390318, DOI: 10.1016/j.ajog.2022.03.063.
- Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study.Hernáez Á, Wootton RE, Page CM, Skåra KH, Fraser A, Rogne T, Magnus P, Njølstad PR, Andreassen OA, Burgess S, Lawlor DA, Magnus MC. Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study. Fertility And Sterility 2022, 118: 180-190. PMID: 35562204, DOI: 10.1016/j.fertnstert.2022.04.001.
- Explaining sex differences in risk of bloodstream infections using mediation analysis in the population-based HUNT study in Norway.Mohus RM, Gustad LT, Furberg AS, Moen MK, Liyanarachi KV, Askim Å, Åsberg SE, DeWan AT, Rogne T, Simonsen GS, Nilsen TIL, Åsvold BO, Damås JK, Solligård E. Explaining sex differences in risk of bloodstream infections using mediation analysis in the population-based HUNT study in Norway. Scientific Reports 2022, 12: 8436. PMID: 35589812, PMCID: PMC9118181, DOI: 10.1038/s41598-022-12569-8.