Research & Publications
Cellular signaling cascades that control cytoskeletal remodeling, adhesion, and migration, are critical to life. The Boggon lab uses structural biology and associated techniques to define the molecular level details that control these pathways. Our primary areas of interest are Rho GTPase and integrin signaling pathways, and the molecular basis for acquisition of cerebral vascular disease. We maintain a focus on the protein kinases involved in these areas.
Biochemistry; Crystallography; Molecular Biology; Protein Kinases; Substrate Specificity; Signal Transduction; Hemangioma, Cavernous, Central Nervous System