Taylor J. Keding, PhD
Research & Publications
Biography
Research Summary
Taylor's research broadly focuses on the interactions between brain and pubertal development, environmental adversity, and psychiatric risk. More specifically, he aims to characterize typical structural and functional brain development during childhood and adolescence and how the timing and tempo of puberty is mediated by neurodevelopment. He is also interested in how neurodevelopment is altered by early-life adversity and how these changes confer risk for psychiatric symptoms. His work makes extensive use of structural and functional MRI, computational modeling, and data science/machine learning approaches.
Research Interests
Brain; Child Development; Puberty; Radiographic Image Interpretation, Computer-Assisted; Stress, Physiological; Stress, Psychological; Computational Biology; Clinical Decision-Making; Machine Learning
Selected Publications
- Differential DNA Methylation is associated with Hippocampal Abnormalities in Pediatric Posttraumatic Stress Disorder.Ensink JBM, Keding TJ, Henneman P, Venema A, Papale LA, Alisch RS, Westerman Y, van Wingen G, Zantvoord J, Middeldorp CM, Mannens MMAM, Herringa RJ, Lindauer RJL. Differential DNA Methylation is associated with Hippocampal Abnormalities in Pediatric Posttraumatic Stress Disorder. Biological Psychiatry : Cognitive Neuroscience And Neuroimaging 2021 PMID: 33964519, DOI: 10.1016/j.bpsc.2021.04.016.
- Neurobehavioral correlates of impaired emotion recognition in pediatric PTSD.Heyn SA, Schmit C, Keding TJ, Wolf R, Herringa RJ. Neurobehavioral correlates of impaired emotion recognition in pediatric PTSD. Development And Psychopathology 2021, 1-11. PMID: 33487187, DOI: 10.1017/S0954579420001704.
- Childhood exposure to interpersonal violence is associated with greater transdiagnostic integration of psychiatric symptoms.Russell JD, Keding TJ, He Q, Li JJ, Herringa RJ. Childhood exposure to interpersonal violence is associated with greater transdiagnostic integration of psychiatric symptoms. Psychological Medicine 2020, 1-9. PMID: 33161911, PMCID: PMC8106688, DOI: 10.1017/S0033291720003712.
- Abnormal Prefrontal Development in Pediatric Posttraumatic Stress Disorder: A Longitudinal Structural and Functional Magnetic Resonance Imaging Study.Heyn SA, Keding TJ, Ross MC, Cisler JM, Mumford JA, Herringa RJ. Abnormal Prefrontal Development in Pediatric Posttraumatic Stress Disorder: A Longitudinal Structural and Functional Magnetic Resonance Imaging Study. Biological Psychiatry : Cognitive Neuroscience And Neuroimaging 2019, 4: 171-179. PMID: 30343133, PMCID: PMC6371792, DOI: 10.1016/j.bpsc.2018.07.013.
- Paradoxical Prefrontal-Amygdala Recruitment to Angry and Happy Expressions in Pediatric Posttraumatic Stress Disorder.Keding TJ, Herringa RJ. Paradoxical Prefrontal-Amygdala Recruitment to Angry and Happy Expressions in Pediatric Posttraumatic Stress Disorder. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology 2016, 41: 2903-2912. PMID: 27329685, PMCID: PMC5061882, DOI: 10.1038/npp.2016.104.
- Default-Mode Network Abnormalities in Pediatric Posttraumatic Stress Disorder.Patriat R, Birn RM, Keding TJ, Herringa RJ. Default-Mode Network Abnormalities in Pediatric Posttraumatic Stress Disorder. Journal Of The American Academy Of Child And Adolescent Psychiatry 2016, 55: 319-27. PMID: 27015723, PMCID: PMC4808564, DOI: 10.1016/j.jaac.2016.01.010.
- Abnormal structure of fear circuitry in pediatric post-traumatic stress disorder.Keding TJ, Herringa RJ. Abnormal structure of fear circuitry in pediatric post-traumatic stress disorder. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology 2015, 40: 537-45. PMID: 25212487, PMCID: PMC4289962, DOI: 10.1038/npp.2014.239.