Taylor J. Keding, PhD
Research & Publications
Biography
Research Summary
Taylor's research broadly focuses on the interactions between brain and pubertal development, environmental adversity, and psychiatric risk. More specifically, he aims to characterize typical structural and functional brain development during childhood and adolescence and how the timing and tempo of puberty is mediated by neurodevelopment. He is also interested in how neurodevelopment is altered by early-life adversity and how these changes confer risk for psychiatric symptoms. His work makes extensive use of structural and functional MRI, computational modeling, and data science/machine learning approaches.
Research Interests
Brain; Child Development; Puberty; Radiographic Image Interpretation, Computer-Assisted; Stress, Physiological; Stress, Psychological; Computational Biology; Clinical Decision-Making; Machine Learning
Selected Publications
- Differential DNA Methylation Is Associated With Hippocampal Abnormalities in Pediatric Posttraumatic Stress DisorderEnsink JBM, Keding TJ, Henneman P, Venema A, Papale LA, Alisch RS, Westerman Y, van Wingen G, Zantvoord J, Middeldorp CM, Mannens MMAM, Herringa RJ, Lindauer R. Differential DNA Methylation Is Associated With Hippocampal Abnormalities in Pediatric Posttraumatic Stress Disorder Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2021, 6: 1063-1070. PMID: 33964519, PMCID: PMC8568739, DOI: 10.1016/j.bpsc.2021.04.016.
- Neurobehavioral correlates of impaired emotion recognition in pediatric PTSDHeyn SA, Schmit C, Keding TJ, Wolf R, Herringa RJ. Neurobehavioral correlates of impaired emotion recognition in pediatric PTSD Development And Psychopathology 2021, 34: 946-956. PMID: 33487187, PMCID: PMC9717496, DOI: 10.1017/s0954579420001704.
- Childhood exposure to interpersonal violence is associated with greater transdiagnostic integration of psychiatric symptomsRussell JD, Keding TJ, He Q, Li JJ, Herringa RJ. Childhood exposure to interpersonal violence is associated with greater transdiagnostic integration of psychiatric symptoms Psychological Medicine 2020, 52: 1883-1891. PMID: 33161911, PMCID: PMC8106688, DOI: 10.1017/s0033291720003712.
- Abnormal Prefrontal Development in Pediatric Posttraumatic Stress Disorder: A Longitudinal Structural and Functional Magnetic Resonance Imaging StudyHeyn SA, Keding TJ, Ross MC, Cisler JM, Mumford JA, Herringa RJ. Abnormal Prefrontal Development in Pediatric Posttraumatic Stress Disorder: A Longitudinal Structural and Functional Magnetic Resonance Imaging Study Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2018, 4: 171-179. PMID: 30343133, PMCID: PMC6371792, DOI: 10.1016/j.bpsc.2018.07.013.
- Paradoxical Prefrontal–Amygdala Recruitment to Angry and Happy Expressions in Pediatric Posttraumatic Stress DisorderKeding TJ, Herringa RJ. Paradoxical Prefrontal–Amygdala Recruitment to Angry and Happy Expressions in Pediatric Posttraumatic Stress Disorder Neuropsychopharmacology 2016, 41: 2903-2912. PMID: 27329685, PMCID: PMC5061882, DOI: 10.1038/npp.2016.104.
- Default-Mode Network Abnormalities in Pediatric Posttraumatic Stress DisorderPatriat R, Birn RM, Keding TJ, Herringa RJ. Default-Mode Network Abnormalities in Pediatric Posttraumatic Stress Disorder Journal Of The American Academy Of Child & Adolescent Psychiatry 2016, 55: 319-327. PMID: 27015723, PMCID: PMC4808564, DOI: 10.1016/j.jaac.2016.01.010.
- Abnormal Structure of Fear Circuitry in Pediatric Post-Traumatic Stress DisorderKeding TJ, Herringa RJ. Abnormal Structure of Fear Circuitry in Pediatric Post-Traumatic Stress Disorder Neuropsychopharmacology 2014, 40: 537-545. PMID: 25212487, PMCID: PMC4289962, DOI: 10.1038/npp.2014.239.