Tassos C. Kyriakides, PhD

• Brian Forsyth
• Cindy Crusto
• David Fiellin
• Elijah Paintsil
• Frederick Altice
• Geoffrey Nadzam
• Gerald Friedland
• James Dziura
• Kimberly Hieftje
• Laurie Andrews
• Linda Mayes
• Lydia Aoun-Barakat
• Lynn E Fiellin
• Marie-Louise Landry
• Michael Kozal
• Peter Peduzzi
• Sandra Resnick
• Sheela Shenoi
• Themis Kyriakides

Clinical Trials as Topic; Epidemiologic Methods; Statistics as Topic; Multicenter Studies as Topic; Epidemiologic Research Design; Survival Analysis; Randomized Controlled Trials as Topic; Controlled Clinical Trials as Topic

Clinical Trials; Global Health; HIV/AIDS; Infectious Diseases

• Effect of Evidence-Based Supported Employment vs Transitional Work on Achieving Steady Work Among Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial.Davis LL, Kyriakides TC, Suris AM, Ottomanelli LA, Mueller L, Parker PE, Resnick SG, Toscano R, Scrymgeour AA, Drake RE. Effect of Evidence-Based Supported Employment vs Transitional Work on Achieving Steady Work Among Veterans With Posttraumatic Stress Disorder: A Randomized Clinical Trial. JAMA Psychiatry 2018, 75: 316-324. PMID: 29490371, PMCID: PMC5875356, DOI: 10.1001/jamapsychiatry.2017.4472.
• Video Game Intervention for Sexual Risk Reduction in Minority Adolescents: Randomized Controlled Trial.Fiellin LE, Hieftje KD, Pendergrass TM, Kyriakides TC, Duncan LR, Dziura JD, Sawyer BG, Mayes L, Crusto CA, Forsyth BW, Fiellin DA. Video Game Intervention for Sexual Risk Reduction in Minority Adolescents: Randomized Controlled Trial. Journal Of Medical Internet Research 2017, 19: e314. PMID: 28923788, PMCID: PMC5625130, DOI: 10.2196/jmir.8148.
• Veterans individual placement and support towards advancing recovery: Methods and baseline clinical characteristics of a multisite study.Davis LL, Kyriakides TC, Suris A, Ottomanelli L, Drake RE, Parker PE, Mueller L, Resnick SG, Toscano R, Blansett CM, McCall KP, Huang GD. Veterans individual placement and support towards advancing recovery: Methods and baseline clinical characteristics of a multisite study. Psychiatric Rehabilitation Journal 2018, 41: 55-66. PMID: 28358525, DOI: 10.1037/prj0000250.
• Variations in the 3'UTR of the CYP21A2 Gene in Heterozygous Females with Hyperandrogenaemia.Neocleous V, Fanis P, Toumba M, Phedonos AAP, Picolos M, Andreou E, Kyriakides TC, Tanteles GA, Shammas C, Phylactou LA, Skordis N. Variations in the 3'UTR of the CYP21A2 Gene in Heterozygous Females with Hyperandrogenaemia. International Journal Of Endocrinology 2017, 2017: 8984365. PMID: 28487735, PMCID: PMC5405599, DOI: 10.1155/2017/8984365.
• Integrated Tuberculosis/Human Immunodeficiency Virus Community-Based Case Finding in Rural South Africa: Implications for Tuberculosis Control Efforts.Shenoi SV, Moll AP, Brooks RP, Kyriakides T, Andrews L, Kompala T, Upadhya D, Altice FL, Eksteen FJ, Friedland G. Integrated Tuberculosis/Human Immunodeficiency Virus Community-Based Case Finding in Rural South Africa: Implications for Tuberculosis Control Efforts. Open Forum Infectious Diseases 2017, 4: ofx092. PMID: 28695145, PMCID: PMC5499582, DOI: 10.1093/ofid/ofx092.
• The design and implementation of a randomized controlled trial of a risk reduction and human immunodeficiency virus prevention videogame intervention in minority adolescents: PlayForward: Elm City Stories.Fiellin LE, Kyriakides TC, Hieftje KD, Pendergrass TM, Duncan LR, Dziura JD, Sawyer BG, Fiellin DA. The design and implementation of a randomized controlled trial of a risk reduction and human immunodeficiency virus prevention videogame intervention in minority adolescents: PlayForward: Elm City Stories. Clinical Trials (London, England) 2016, 13: 400-8. PMID: 27013483, PMCID: PMC4942329, DOI: 10.1177/1740774516637871.
• Characterizing Patients with Very-Low-Level HIV Viremia: A Community-Based Study.Helou E, Shenoi S, Kyriakides T, Landry ML, Kozal M, Barakat LA. Characterizing Patients with Very-Low-Level HIV Viremia: A Community-Based Study. Journal Of The International Association Of Providers Of AIDS Care 2017, 16: 261-266. PMID: 27903948, PMCID: PMC5423832, DOI: 10.1177/2325957416680028.
• Long-term Cost-effectiveness in the Veterans Affairs Open vs Endovascular Repair Study of Aortic Abdominal Aneurysm: A Randomized Clinical Trial.Lederle FA, Stroupe KT, Kyriakides TC, Ge L, Freischlag JA. Long-term Cost-effectiveness in the Veterans Affairs Open vs Endovascular Repair Study of Aortic Abdominal Aneurysm: A Randomized Clinical Trial. JAMA Surgery 2016, 151: 1139-1144. PMID: 27627802, DOI: 10.1001/jamasurg.2016.2783.
• Sankofa pediatric HIV disclosure intervention cyber data management: building capacity in a resource-limited setting and ensuring data quality.Catlin AC, Fernando S, Gamage R, Renner L, Antwi S, Tettey JK, Amisah KA, Kyriakides T, Cong X, Reynolds NR, Paintsil E. Sankofa pediatric HIV disclosure intervention cyber data management: building capacity in a resource-limited setting and ensuring data quality. AIDS Care 2015, 27 Suppl 1: 99-107. PMID: 26616131, PMCID: PMC4704410, DOI: 10.1080/09540121.2015.1023246.
• HIV knowledge, stigma, and illness beliefs among pediatric caregivers in Ghana who have not disclosed their child's HIV status.Paintsil E, Renner L, Antwi S, Dame J, Enimil A, Ofori-Atta A, Alhassan A, Ofori IP, Cong X, Kyriakides T, Reynolds NR. HIV knowledge, stigma, and illness beliefs among pediatric caregivers in Ghana who have not disclosed their child's HIV status. AIDS Care 2015, 27 Suppl 1: 18-27. PMID: 26616122, PMCID: PMC4665118, DOI: 10.1080/09540121.2015.1007116.
• Predictors and outcomes of endoleaks in the Veterans Affairs Open Versus Endovascular Repair (OVER) Trial of Abdominal Aortic Aneurysms.Lal BK, Zhou W, Li Z, Kyriakides T, Matsumura J, Lederle FA, Freischlag J. Predictors and outcomes of endoleaks in the Veterans Affairs Open Versus Endovascular Repair (OVER) Trial of Abdominal Aortic Aneurysms. Journal Of Vascular Surgery 2015, 62: 1394-404. PMID: 26598115, DOI: 10.1016/j.jvs.2015.02.003.
• Trends in hospital deaths among human immunodeficiency virus-infected patients during the antiretroviral therapy era, 1995 to 2011.Cowell A, Shenoi SV, Kyriakides TC, Friedland G, Barakat LA. Trends in hospital deaths among human immunodeficiency virus-infected patients during the antiretroviral therapy era, 1995 to 2011. Journal Of Hospital Medicine 2015, 10: 608-14. PMID: 26130520, PMCID: PMC4560992, DOI: 10.1002/jhm.2409.
• Elevated Muscle-Specific miRNAs in Serum of Myotonic Dystrophy Patients Relate to Muscle Disease Progress.Koutsoulidou A, Kyriakides TC, Papadimas GK, Christou Y, Kararizou E, Papanicolaou EZ, Phylactou LA. Elevated Muscle-Specific miRNAs in Serum of Myotonic Dystrophy Patients Relate to Muscle Disease Progress. PloS One 2015, 10: e0125341. PMID: 25915631, PMCID: PMC4411125, DOI: 10.1371/journal.pone.0125341.
• Long-term comparison of endovascular and open repair of abdominal aortic aneurysm.Lederle FA, Freischlag JA, Kyriakides TC, Matsumura JS, Padberg FT, Kohler TR, Kougias P, Jean-Claude JM, Cikrit DF, Swanson KM. Long-term comparison of endovascular and open repair of abdominal aortic aneurysm. The New England Journal Of Medicine 2012, 367: 1988-97. PMID: 23171095, DOI: 10.1056/NEJMoa1207481.
• Epidemiology of type 1 diabetes mellitus in Cyprus: rising incidence at the dawn of the 21st century.Skordis N, Efstathiou E, Kyriakides TC, Savvidou A, Savva SC, Phylactou LA, Shammas C, Neocleous V. Epidemiology of type 1 diabetes mellitus in Cyprus: rising incidence at the dawn of the 21st century. Hormones (Athens, Greece) 2012, 11: 86-93. PMID: 22450348, DOI: 10.1007/BF03401541.
• Cost-effectiveness of open versus endovascular repair of abdominal aortic aneurysm in the OVER trial.Stroupe KT, Lederle FA, Matsumura JS, Kyriakides TC, Jonk YC, Ge L, Freischlag JA. Cost-effectiveness of open versus endovascular repair of abdominal aortic aneurysm in the OVER trial. Journal Of Vascular Surgery 2012, 56: 901-9.e2. PMID: 22640466, DOI: 10.1016/j.jvs.2012.01.086.
• Predictive value of HIV-1 replication capacity and phenotypic susceptibility scores in antiretroviral treatment-experienced patients.Bedimo R, Kyriakides T, Brown S, Weidler J, Lie Y, Coakley E, Holodniy M. Predictive value of HIV-1 replication capacity and phenotypic susceptibility scores in antiretroviral treatment-experienced patients. HIV Medicine 2012, 13: 345-51. PMID: 22276745, DOI: 10.1111/j.1468-1293.2011.00981.x.
• Surgical Resident Attrition and the Menninger Morale Curve.Contessa J., Nadzam G. and Kyriakides TC. Surgical Science, 2011 (2):397-401
• Can moral reasoning predict general surgery residents' clinical competence?Contessa J, Kyriakides T, Kim D. Can moral reasoning predict general surgery residents' clinical competence? Journal Of Surgical Education 2012, 69: 17-22. PMID: 22208826, DOI: 10.1016/j.jsurg.2011.06.014.
• Results of antiretroviral treatment interruption and intensification in advanced multi-drug resistant HIV infection from the OPTIMA trial.Holodniy M, Brown ST, Cameron DW, Kyriakides TC, Angus B, Babiker A, Singer J, Owens DK, Anis A, Goodall R, Hudson F, Piaseczny M, Russo J, Schechter M, Deyton L, Darbyshire J. Results of antiretroviral treatment interruption and intensification in advanced multi-drug resistant HIV infection from the OPTIMA trial. PloS One 2011, 6: e14764. PMID: 21483491, PMCID: PMC3069000, DOI: 10.1371/journal.pone.0014764.
• Effect of treatment interruption and intensification of antiretroviral therapy on health-related quality of life in patients with advanced HIV: a randomized, controlled trial.Joyce VR, Barnett PG, Chow A, Bayoumi AM, Griffin SC, Sun H, Holodniy M, Brown ST, Kyriakides TC, Cameron DW, Youle M, Sculpher M, Anis AH, Owens DK. Effect of treatment interruption and intensification of antiretroviral therapy on health-related quality of life in patients with advanced HIV: a randomized, controlled trial. Medical Decision Making : An International Journal Of The Society For Medical Decision Making 2012, 32: 70-82. PMID: 21383086, DOI: 10.1177/0272989X10397615.
• Methodological issues in comparative effectiveness research: clinical trials.Peduzzi P, Kyriakides T, O'Connor TZ, Guarino P, Warren SR, Huang GD. Methodological issues in comparative effectiveness research: clinical trials. The American Journal Of Medicine 2010, 123: e8-15. PMID: 21184867, DOI: 10.1016/j.amjmed.2010.10.003.
• Connection domain mutations in treatment-experienced patients in the OPTIMA trial.Dau B, Ayers D, Singer J, Harrigan PR, Brown S, Kyriakides T, Cameron DW, Angus B, Holodniy M. Connection domain mutations in treatment-experienced patients in the OPTIMA trial. Journal Of Acquired Immune Deficiency Syndromes (1999) 2010, 54: 160-6. PMID: 20130473, DOI: 10.1097/QAI.0b013e3181cbd235.
• Outcomes following endovascular vs open repair of abdominal aortic aneurysm: a randomized trial.Lederle FA, Freischlag JA, Kyriakides TC, Padberg FT, Matsumura JS, Kohler TR, Lin PH, Jean-Claude JM, Cikrit DF, Swanson KM, Peduzzi PN. Outcomes following endovascular vs open repair of abdominal aortic aneurysm: a randomized trial. JAMA 2009, 302: 1535-42. PMID: 19826022, DOI: 10.1001/jama.2009.1426.
• Quality of life of patients with advanced HIV/AIDS: measuring the impact of both AIDS-defining events and non-AIDS serious adverse events.Anis AH, Nosyk B, Sun H, Guh DP, Bansback N, Li X, Barnett PG, Joyce V, Swanson KM, Kyriakides TC, Holodniy M, Cameron DW, Brown ST. Quality of life of patients with advanced HIV/AIDS: measuring the impact of both AIDS-defining events and non-AIDS serious adverse events. Journal Of Acquired Immune Deficiency Syndromes (1999) 2009, 51: 631-9. PMID: 19430303, DOI: 10.1097/QAI.0b013e3181a4f00d.
• Early postoperative hemorrhage after open and laparoscopic roux-en-y gastric bypass.Bakhos C, Alkhoury F, Kyriakides T, Reinhold R, Nadzam G. Early postoperative hemorrhage after open and laparoscopic roux-en-y gastric bypass. Obesity Surgery 2009, 19: 153-157. PMID: 18629595, DOI: 10.1007/s11695-008-9580-1.
• Health-related quality of life in a randomized trial of antiretroviral therapy for advanced HIV disease.Joyce VR, Barnett PG, Bayoumi AM, Griffin SC, Kyriakides TC, Yu W, Sundaram V, Holodniy M, Brown ST, Cameron W, Youle M, Sculpher M, Anis AH, Owens DK. Health-related quality of life in a randomized trial of antiretroviral therapy for advanced HIV disease. Journal Of Acquired Immune Deficiency Syndromes (1999) 2009, 50: 27-36. PMID: 19295332, DOI: 10.1097/QAI.0b013e31818ce6f3.
• The effect of myotonic dystrophy transcript levels and location on muscle differentiation.Mastroyiannopoulos NP, Chrysanthou E, Kyriakides TC, Uney JB, Mahadevan MS, Phylactou LA. The effect of myotonic dystrophy transcript levels and location on muscle differentiation. Biochemical And Biophysical Research Communications 2008, 377: 526-531. PMID: 18930030, DOI: 10.1016/j.bbrc.2008.10.031.
• Evolution of genotypic resistance algorithms and their impact on the interpretation of clinical trials: an OPTIMA trial substudy.Desai S, Kyriakides T, Holodniy M, Al-Salman J, Griffith B, Kozal M. Evolution of genotypic resistance algorithms and their impact on the interpretation of clinical trials: an OPTIMA trial substudy. HIV Clinical Trials 2007, 8: 293-302. PMID: 17956830, DOI: 10.1310/hct0805-293.
• Vital capacity as a predictor of outcome in elderly patients with rib fractures.Bakhos C, O'Connor J, Kyriakides T, Abou-Nukta F, Bonadies J. Vital capacity as a predictor of outcome in elderly patients with rib fractures. The Journal Of Trauma 2006, 61: 131-4. PMID: 16832260, DOI: 10.1097/01.ta.0000223463.88422.6a.
• Study conduct, monitoring and data management in a trinational trial: the OPTIMA model.Kyriakides TC, Babiker A, Singer J, Piaseczny M, Russo J. Study conduct, monitoring and data management in a trinational trial: the OPTIMA model. Clinical Trials (London, England) 2004, 1: 277-81. PMID: 16279253, DOI: 10.1191/1740774504cn022oa.
• An open-label randomized clinical trial of novel therapeutic strategies for HIV-infected patients in whom antiretroviral therapy has failed: rationale and design of the OPTIMA Trial.Kyriakides TC, Babiker A, Singer J, Cameron W, Schechter MT, Holodniy M, Brown ST, Youle M, Gazzard B. An open-label randomized clinical trial of novel therapeutic strategies for HIV-infected patients in whom antiretroviral therapy has failed: rationale and design of the OPTIMA Trial. Controlled Clinical Trials 2003, 24: 481-500. PMID: 12865041, DOI: 10.1016/s0197-2456(03)00029-1.
• Surveillance of HIV in the army of the Republic of Cyprus (SHARC); rationale, design, and implementation of an inexpensive system.Kyriakides T, Eleftheriou A, Michaelides N, Papantoniou L. Surveillance of HIV in the army of the Republic of Cyprus (SHARC); rationale, design, and implementation of an inexpensive system. Sexually Transmitted Infections 2002, 78: 50-2. PMID: 11872860, PMCID: PMC1763710, DOI: 10.1136/sti.78.1.50.
• Development and application of a genotypic AZT resistance assay: quantitative assessment of the resistance profile of clinical samples and the relative predictive ability of a resistance index.Kyriakides TC, Heimer RR. Development and application of a genotypic AZT resistance assay: quantitative assessment of the resistance profile of clinical samples and the relative predictive ability of a resistance index. Journal Of Acquired Immune Deficiency Syndromes (1999) 2001, 28: 211-20. PMID: 11694826, DOI: 10.1097/00042560-200111010-00002.