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Tamas Horvath, DVM, PhD

Jean and David W. Wallace Professor of Comparative Medicine and Professor of Neuroscience and of Obstetrics, Gynecology, and Reproductive Sciences; Chair, Department of Comparative Medicine; Director, Yale Program in Integrative Cell Signaling and Neurobiology of Metabolism

Research Summary

My main interest is the neuroendocrine regulation of homeostasis with particular emphasis on metabolic disorders, such as obesity and diabetes, and the effect of metabolic signals on higher brain functions and neurodegeneration. We have active research programs to pursue the role of synaptic plasticity in the mediation of peripheral hormones’ effects on the central nervous system.

We also study the role of mitochondrial membrane potential in normal and pathological brain functions with particular emphasis on the acute effect of mitochondria in neuronal transmission and neuroprotection. We combine classical neurobiological approaches, including electrophysiology and neuroanatomy, with endocrine and genetic techniques to better understand biological events at the level of the organism.

Specialized Terms: Neurobiology of obesity; Neuroendocrine physiology

Coauthors

Research Interests

Neuroendocrinology; Obesity; Physiology

Selected Publications