Sumit Jamwal, PhD
Postdoctoral Associate
Research & Publications
Biography
Coauthors
Selected Publications
- Age-associated sex difference in the expression of mitochondria-based redox sensitive proteins and effect of pioglitazone in nonhuman primate brainJamwal S, Blackburn J, Elsworth J. Age-associated sex difference in the expression of mitochondria-based redox sensitive proteins and effect of pioglitazone in nonhuman primate brain. Biology Of Sex Differences 2023, 14: 65. PMID: 37770961, PMCID: PMC10540392, DOI: 10.1186/s13293-023-00551-6.
- Animal models of Huntington’s disease and their applicability to novel drug discovery and developmentUpadhayay S, Jamwal S, Kumar P. Animal models of Huntington’s disease and their applicability to novel drug discovery and development. Expert Opinion On Drug Discovery 2023, 18: 527-538. PMID: 37042034, DOI: 10.1080/17460441.2023.2201493.
- An Overview of the Pathophysiological Mechanisms of 3-Nitropropionic Acid (3-NPA) as a Neurotoxin in a Huntington's Disease Model and Its Relevance to Drug Discovery and DevelopmentUpadhayay S, Yedke N, Rahi V, Singh S, Kumar S, Arora A, Chandolia P, Kaur P, Kumar M, Koshal P, Jamwal S, Kumar P. An Overview of the Pathophysiological Mechanisms of 3-Nitropropionic Acid (3-NPA) as a Neurotoxin in a Huntington's Disease Model and Its Relevance to Drug Discovery and Development. Neurochemical Research 2023, 48: 1631-1647. PMID: 36738367, DOI: 10.1007/s11064-023-03868-1.
- miRNA‐encapsulated abiotic materials and biovectors for cutaneous and oral wound healing: Biogenesis, mechanisms, and delivery nanocarriersDey A, Yousefiasl S, Kumar A, Moghaddam F, Rahimmanesh I, Samandari M, Jamwal S, Maleki A, Mohammadi A, Rabiee N, Paiva‐Santos A, Tamayol A, Sharifi E, Makvandi P. miRNA‐encapsulated abiotic materials and biovectors for cutaneous and oral wound healing: Biogenesis, mechanisms, and delivery nanocarriers. Bioengineering & Translational Medicine 2022, 8: e10343. PMID: 36684081, PMCID: PMC9842058, DOI: 10.1002/btm2.10343.
- Expression of PON2 isoforms varies among brain regions in male and female African green monkeysJamwal S, Blackburn JK, Elsworth JD. Expression of PON2 isoforms varies among brain regions in male and female African green monkeys. Free Radical Biology And Medicine 2021, 178: 215-218. PMID: 34890766, PMCID: PMC8760629, DOI: 10.1016/j.freeradbiomed.2021.12.005.
- Pioglitazone transiently stimulates paraoxonase-2 expression in male nonhuman primate brain: Implications for sex-specific therapeutics in neurodegenerative disordersBlackburn JK, Jamwal S, Wang W, Elsworth JD. Pioglitazone transiently stimulates paraoxonase-2 expression in male nonhuman primate brain: Implications for sex-specific therapeutics in neurodegenerative disorders. Neurochemistry International 2021, 152: 105222. PMID: 34767873, PMCID: PMC8712400, DOI: 10.1016/j.neuint.2021.105222.
- Role of vitamins and minerals as immunity boosters in COVID-19Kumar P, Kumar M, Bedi O, Gupta M, Kumar S, Jaiswal G, Rahi V, Yedke NG, Bijalwan A, Sharma S, Jamwal S. Role of vitamins and minerals as immunity boosters in COVID-19. Inflammopharmacology 2021, 29: 1001-1016. PMID: 34110533, PMCID: PMC8190991, DOI: 10.1007/s10787-021-00826-7.
- Sex-based disparity in paraoxonase-2 expression in the brains of African green monkeysJamwal S, Blackburn JK, Elsworth JD. Sex-based disparity in paraoxonase-2 expression in the brains of African green monkeys. Free Radical Biology And Medicine 2021, 167: 201-204. PMID: 33722626, PMCID: PMC8096713, DOI: 10.1016/j.freeradbiomed.2021.03.003.
- Neuroprotection through G-CSF: recent advances and future viewpointsRahi V, Jamwal S, Kumar P. Neuroprotection through G-CSF: recent advances and future viewpoints. Pharmacological Reports 2021, 73: 372-385. PMID: 33389706, DOI: 10.1007/s43440-020-00201-3.
- Chapter 5 Protocols in apoptosis identification and affirmationJamwal S, Kumar P, Kakkar V, Kumari P, Chahal S. Chapter 5 Protocols in apoptosis identification and affirmation. 2021, 127-152. DOI: 10.1016/b978-0-12-815762-6.00005-6.
- Exploring the molecular approach of COX and LOX in Alzheimer’s and Parkinson’s disorderKumar A, Behl T, Jamwal S, Kaur I, Sood A, Kumar P. Exploring the molecular approach of COX and LOX in Alzheimer’s and Parkinson’s disorder. Molecular Biology Reports 2020, 47: 9895-9912. PMID: 33263931, DOI: 10.1007/s11033-020-06033-x.
- PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disordersJamwal S, Blackburn J, Elsworth JD. PPARγ/PGC1α signaling as a potential therapeutic target for mitochondrial biogenesis in neurodegenerative disorders. Pharmacology & Therapeutics 2020, 219: 107705. PMID: 33039420, PMCID: PMC7887032, DOI: 10.1016/j.pharmthera.2020.107705.
- Gene therapy and immunotherapy as promising strategies to combat Huntington’s disease-associated neurodegeneration: emphasis on recent updates and future perspectivesJamwal S, Elsworth JD, Rahi V, Kumar P. Gene therapy and immunotherapy as promising strategies to combat Huntington’s disease-associated neurodegeneration: emphasis on recent updates and future perspectives. Expert Review Of Neurotherapeutics 2020, 20: 1123-1141. PMID: 32720531, DOI: 10.1080/14737175.2020.1801424.
- An updated insight into the molecular pathogenesis, secondary complications and potential therapeutics of COVID-19 pandemicJamwal S, Gautam A, Elsworth J, Kumar M, Chawla R, Kumar P. An updated insight into the molecular pathogenesis, secondary complications and potential therapeutics of COVID-19 pandemic. Life Sciences 2020, 257: 118105. PMID: 32687917, PMCID: PMC7366108, DOI: 10.1016/j.lfs.2020.118105.
- Protective Effect of Hemin Against Experimental Chronic Fatigue Syndrome in Mice: Possible Role of NeurotransmittersThakur V, Jamwal S, Kumar M, Rahi V, Kumar P. Protective Effect of Hemin Against Experimental Chronic Fatigue Syndrome in Mice: Possible Role of Neurotransmitters. Neurotoxicity Research 2020, 38: 359-369. PMID: 32506340, DOI: 10.1007/s12640-020-00231-y.
- P2‐164: NEUROPROTECTIVE MECHANISM OF SPERMIDINE ALONE AND IN COMBINATION WITH NITRIC OXIDE PATHWAY MODULATORS AGAINST 3‐NP‐INDUCED BEHAVIORAL, BIOCHEMICAL AND NEUROTRANSMITTER ALTERATIONS IN RAT STRIATUMJamwal S. P2‐164: NEUROPROTECTIVE MECHANISM OF SPERMIDINE ALONE AND IN COMBINATION WITH NITRIC OXIDE PATHWAY MODULATORS AGAINST 3‐NP‐INDUCED BEHAVIORAL, BIOCHEMICAL AND NEUROTRANSMITTER ALTERATIONS IN RAT STRIATUM. Alzheimer's & Dementia 2019, 15: p638-p638. DOI: 10.1016/j.jalz.2019.06.2571.
- Insight Into the Emerging Role of Striatal Neurotransmitters in the Pathophysiology of Parkinson’s Disease and Huntington’s Disease: A ReviewJamwal S, Kumar P. Insight Into the Emerging Role of Striatal Neurotransmitters in the Pathophysiology of Parkinson’s Disease and Huntington’s Disease: A Review. Current Neuropharmacology 2019, 17: 165-175. PMID: 29512464, PMCID: PMC6343208, DOI: 10.2174/1570159x16666180302115032.
- Protective Effect of Agomelatine on Traumatic Brain Injury Induced Cognitive Deficit in Rats: Possible Role of NeurotransmittersKaur T, Kumar P, Jamwal S. Protective Effect of Agomelatine on Traumatic Brain Injury Induced Cognitive Deficit in Rats: Possible Role of Neurotransmitters. Current Psychopharmacologye 2019, 7: 192-207. DOI: 10.2174/2211556007666180601100641.
- Neurochemical Imbalance in Epilepsy from Animal Model to HumanKumar M, Kumar P, Koshal P, Jamwal S. Neurochemical Imbalance in Epilepsy from Animal Model to Human. Current Psychopharmacologye 2019, 7: 113-128. DOI: 10.2174/2211556007666180522084412.
- Therapeutic Potential of Agonists and Antagonists of A1, A2a, A2b and A3 Adenosine Receptors.Jamwal S, Mittal A, Kumar P, Alhayani DM, Al-Aboudi A. Therapeutic Potential of Agonists and Antagonists of A1, A2a, A2b and A3 Adenosine Receptors. Current Pharmaceutical Design 2019, 25: 2892-2905. PMID: 31333104, DOI: 10.2174/1381612825666190716112319.
- Management of HD: Insight into Molecular Mechanisms and Potential Neuroprotective Drug StrategiesKumar P, Jamwal S, Kumar A. Management of HD: Insight into Molecular Mechanisms and Potential Neuroprotective Drug Strategies. 2018, 197-206. DOI: 10.1007/978-981-13-0944-1_18.
- Glucagon-like Peptide-1 (GLP-1) and neurotransmitters signaling in epilepsy: An insight reviewKoshal P, Jamwal S, Kumar P. Glucagon-like Peptide-1 (GLP-1) and neurotransmitters signaling in epilepsy: An insight review. Neuropharmacology 2017, 136: 271-279. PMID: 29129776, DOI: 10.1016/j.neuropharm.2017.11.015.
- L-theanine, a component of green tea spares striatal neurons from 3-NP induced neurotoxicity: Role of nitric oxide pathwayJamwal S, Kumar P. L-theanine, a component of green tea spares striatal neurons from 3-NP induced neurotoxicity: Role of nitric oxide pathway. Journal Of The Neurological Sciences 2017, 381: 354. DOI: 10.1016/j.jns.2017.08.1006.
- The malleable brain: plasticity of neural circuits and behavior – a review from students to studentsSchaefer N, Rotermund C, Blumrich E, Lourenco MV, Joshi P, Hegemann RU, Jamwal S, Ali N, Romero E, Sharma S, Ghosh S, Sinha JK, Loke H, Jain V, Lepeta K, Salamian A, Sharma M, Golpich M, Nawrotek K, Paidi RK, Shahidzadeh SM, Piermartiri T, Amini E, Pastor V, Wilson Y, Adeniyi PA, Datusalia AK, Vafadari B, Saini V, Suárez‐Pozos E, Kushwah N, Fontanet P, Turner AJ. The malleable brain: plasticity of neural circuits and behavior – a review from students to students. Journal Of Neurochemistry 2017, 142: 790-811. PMID: 28632905, DOI: 10.1111/jnc.14107.
- L-theanine prevent quinolinic acid induced motor deficit and striatal neurotoxicity: Reduction in oxido-nitrosative stress and restoration of striatal neurotransmitters levelJamwal S, Singh S, Gill JS, Kumar P. L-theanine prevent quinolinic acid induced motor deficit and striatal neurotoxicity: Reduction in oxido-nitrosative stress and restoration of striatal neurotransmitters level. European Journal Of Pharmacology 2017, 811: 171-179. PMID: 28624333, DOI: 10.1016/j.ejphar.2017.06.016.
- Neuroprotective potential of quercetin in combination with piperine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicitySingh S, Jamwal S, Kumar P. Neuroprotective potential of quercetin in combination with piperine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. Neural Regeneration Research 2017, 12: 1137-1144. PMID: 28852397, PMCID: PMC5558494, DOI: 10.4103/1673-5374.211194.
- Chapter 19 Animal Models of Inflammatory Bowel DiseaseJamwal S, Kumar P. Chapter 19 Animal Models of Inflammatory Bowel Disease. 2017, 467-477. DOI: 10.1016/b978-0-12-809468-6.00019-x.
- Animal Models of AutismSharma N, Jamwal S, Bansal P. Animal Models of Autism. 2017, 233-247. DOI: 10.1007/978-981-10-5981-0_15.
- Animal Models of Parkinson’s DiseaseSharma N, Jamwal S, Singh S, Gill H, Bansal P. Animal Models of Parkinson’s Disease. 2017, 23-42. DOI: 10.1007/978-981-10-5981-0_3.
- Animal Models of Tardive DyskinesiaDatta S, Jamwal S, Akula K, Bansal P. Animal Models of Tardive Dyskinesia. 2017, 79-88. DOI: 10.1007/978-981-10-5981-0_6.
- Animal Models of Traumatic Brain InjuryKaur T, Jamwal S, Bansal P. Animal Models of Traumatic Brain Injury. 2017, 89-103. DOI: 10.1007/978-981-10-5981-0_7.
- Behavioral Tests for Rodent ModelsJamwal S, Singh S, Bansal P. Behavioral Tests for Rodent Models. 2017, 315-341. DOI: 10.1007/978-981-10-5981-0_21.
- Animal Models of MigraineJamwal S, Singh S, Bansal P. Animal Models of Migraine. 2017, 105-115. DOI: 10.1007/978-981-10-5981-0_8.
- Animal Model of Amyotrophic Lateral SclerosisKoshal P, Kumar M, Jamwal S, Bansal P. Animal Model of Amyotrophic Lateral Sclerosis. 2017, 277-289. DOI: 10.1007/978-981-10-5981-0_18.
- Animal Models of SchizophreniaBedi O, Jamwal S, Singh S, Bhakuni G, Bansal P. Animal Models of Schizophrenia. 2017, 117-137. DOI: 10.1007/978-981-10-5981-0_9.
- Animal Models of Huntington’s DiseaseKaur N, Jamwal S, Kaur Gill H, Bansal P. Animal Models of Huntington’s Disease. 2017, 43-57. DOI: 10.1007/978-981-10-5981-0_4.
- Animal Models of EpilepsyKoshal P, Jamwal S, Akula K, Bansal P. Animal Models of Epilepsy. 2017, 59-78. DOI: 10.1007/978-981-10-5981-0_5.
- Animal Model of AnxietyBansal P, Singh S, Jamwal S. Animal Model of Anxiety. 2017, 139-158. DOI: 10.1007/978-981-10-5981-0_10.
- Animal Models of Attention-Deficit Hyperkinetic Disorder (ADHD)Sharma N, Jamwal S, Bansal P. Animal Models of Attention-Deficit Hyperkinetic Disorder (ADHD). 2017, 217-232. DOI: 10.1007/978-981-10-5981-0_14.
- Sertraline and venlafaxine improves motor performance and neurobehavioral deficit in quinolinic acid induced Huntington’s like symptoms in rats: Possible neurotransmitters modulationGill JS, Jamwal S, Kumar P, Deshmukh R. Sertraline and venlafaxine improves motor performance and neurobehavioral deficit in quinolinic acid induced Huntington’s like symptoms in rats: Possible neurotransmitters modulation. Pharmacological Reports 2016, 69: 306-313. PMID: 28178592, DOI: 10.1016/j.pharep.2016.11.008.
- Tetrabenazine: Spotlight on Drug ReviewKaur N, Kumar P, Jamwal S, Deshmukh R, Gauttam V. Tetrabenazine: Spotlight on Drug Review. Annals Of Neurosciences 2016, 23: 176-185. PMID: 27721587, PMCID: PMC5043267, DOI: 10.1159/000449184.
- P2‐116: L‐Theanine Spares Striatal Neurons From 3‐NP–Induced Striatal Neurotoxicity: Role of Nitric Oxide PathwayJamwal S, Kumar P. P2‐116: L‐Theanine Spares Striatal Neurons From 3‐NP–Induced Striatal Neurotoxicity: Role of Nitric Oxide Pathway. Alzheimer's & Dementia 2016, 12: p656-p656. DOI: 10.1016/j.jalz.2016.06.1486.
- Beneficial effect of antidepressants against rotenone induced Parkinsonism like symptoms in ratsSharma N, Jamwal S, Kumar P. Beneficial effect of antidepressants against rotenone induced Parkinsonism like symptoms in rats. Pathophysiology 2016, 23: 123-134. PMID: 26996500, DOI: 10.1016/j.pathophys.2016.03.002.
- L-theanine, a Component of Green Tea Prevents 3-Nitropropionic Acid (3-NP)-Induced Striatal Toxicity by Modulating Nitric Oxide PathwayJamwal S, Kumar P. L-theanine, a Component of Green Tea Prevents 3-Nitropropionic Acid (3-NP)-Induced Striatal Toxicity by Modulating Nitric Oxide Pathway. Molecular Neurobiology 2016, 54: 2327-2337. PMID: 26957301, DOI: 10.1007/s12035-016-9822-5.
- Beneficial effects of lycopene against haloperidol induced orofacial dyskinesia in rats: Possible neurotransmitters and neuroinflammation modulationDatta S, Jamwal S, Deshmukh R, Kumar P. Beneficial effects of lycopene against haloperidol induced orofacial dyskinesia in rats: Possible neurotransmitters and neuroinflammation modulation. European Journal Of Pharmacology 2015, 771: 229-235. PMID: 26712377, DOI: 10.1016/j.ejphar.2015.12.032.
- Spermidine ameliorates 3-nitropropionic acid (3-NP)-induced striatal toxicity: Possible role of oxidative stress, neuroinflammation, and neurotransmittersJamwal S, Kumar P. Spermidine ameliorates 3-nitropropionic acid (3-NP)-induced striatal toxicity: Possible role of oxidative stress, neuroinflammation, and neurotransmitters. Physiology & Behavior 2015, 155: 180-187. PMID: 26703234, DOI: 10.1016/j.physbeh.2015.12.015.
- Antidepressants for neuroprotection in Huntington's disease: A reviewJamwal S, Kumar P. Antidepressants for neuroprotection in Huntington's disease: A review. European Journal Of Pharmacology 2015, 769: 33-42. PMID: 26511378, DOI: 10.1016/j.ejphar.2015.10.033.
- Beneficial effect of zinc chloride and zinc ionophore pyrithione on attenuated cardioprotective potential of preconditioning phenomenon in STZ-induced diabetic rat heartJamwal S, Kumar K, Reddy BV. Beneficial effect of zinc chloride and zinc ionophore pyrithione on attenuated cardioprotective potential of preconditioning phenomenon in STZ-induced diabetic rat heart. Perfusion 2015, 31: 334-342. PMID: 26423303, DOI: 10.1177/0267659115608935.
- Beneficial effect of rice bran extract against 3-nitropropionic acid induced experimental Huntington's disease in ratsKaur N, Jamwal S, Deshmukh R, Gauttam V, Kumar P. Beneficial effect of rice bran extract against 3-nitropropionic acid induced experimental Huntington's disease in rats. Toxicology Reports 2015, 2: 1222-1232. PMID: 28962465, PMCID: PMC5598492, DOI: 10.1016/j.toxrep.2015.08.004.
- Piperine Enhances the Protective Effect of Curcumin Against 3-NP Induced Neurotoxicity: Possible Neurotransmitters Modulation MechanismSingh S, Jamwal S, Kumar P. Piperine Enhances the Protective Effect of Curcumin Against 3-NP Induced Neurotoxicity: Possible Neurotransmitters Modulation Mechanism. Neurochemical Research 2015, 40: 1758-1766. PMID: 26160706, DOI: 10.1007/s11064-015-1658-2.
- P3‐324: Beneficial effect of spermidine against 3‐nitropropionic acid‐induced neurotoxicity in rats: Possible neurotransmitter modulationKumar P, Jamwal S. P3‐324: Beneficial effect of spermidine against 3‐nitropropionic acid‐induced neurotoxicity in rats: Possible neurotransmitter modulation. Alzheimer's & Dementia 2015, 11: p762-p762. DOI: 10.1016/j.jalz.2015.06.1698.
- Protective Effect of Spermidine Against Excitotoxic Neuronal Death Induced by Quinolinic Acid in Rats: Possible Neurotransmitters and Neuroinflammatory MechanismJamwal S, Singh S, Kaur N, Kumar P. Protective Effect of Spermidine Against Excitotoxic Neuronal Death Induced by Quinolinic Acid in Rats: Possible Neurotransmitters and Neuroinflammatory Mechanism. Neurotoxicity Research 2015, 28: 171-184. PMID: 26078029, DOI: 10.1007/s12640-015-9535-y.
- Neuroprotective effect of hemeoxygenase-1/glycogen synthase kinase-3β modulators in 3-nitropropionic acid-induced neurotoxicity in ratsKhan A, Jamwal S, Bijjem K, Prakash A, Kumar P. Neuroprotective effect of hemeoxygenase-1/glycogen synthase kinase-3β modulators in 3-nitropropionic acid-induced neurotoxicity in rats. Neuroscience 2014, 287: 66-77. PMID: 25536048, DOI: 10.1016/j.neuroscience.2014.12.018.
- Mechanisms involved in attenuated cardio-protective role of ischemic preconditioning in metabolic disordersRana A, Goyal N, Ahlawat A, Jamwal S, Reddy B, Sharma S. Mechanisms involved in attenuated cardio-protective role of ischemic preconditioning in metabolic disorders. Perfusion 2014, 30: 94-105. PMID: 24947460, DOI: 10.1177/0267659114536760.
- Polymeric microparticles-based formulation for the eradication of cutaneous candidiasis: development and characterizationKumar L, Verma S, Jamwal S, Vaidya S, Vaidya B. Polymeric microparticles-based formulation for the eradication of cutaneous candidiasis: development and characterization. Pharmaceutical Development And Technology 2013, 19: 318-325. PMID: 23560821, DOI: 10.3109/10837450.2013.778874.