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Stephen Holt

MD, MS, FACP
Associate Professor of Medicine (General Medicine); Director, Addiction Recovery Clinic, Internal Medicine; Co-Director, Clinician Educator Distinctions Pathway, Internal Medicine; Associate Program Director, Ambulatory Education, Yale Primary Care Residency Program, Internal Medicine

Contact Information

Stephen Holt, MD, MS, FACP
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Yale Medicine

Patient Care

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Coauthors

Research Interests

Education, Medical; History of Medicine; Substance-Related Disorders

Selected Publications

  • Prevalence of unhealthy substance use on teaching and hospitalist medical services: implications for education.Holt SR, Ramos J, Harma MA, Cabrera F, Louis-Ashby C, Dinh A, Tetrault JM, Fiellin DA. Prevalence of unhealthy substance use on teaching and hospitalist medical services: implications for education. The American Journal On Addictions / American Academy Of Psychiatrists In Alcoholism And Addictions 2012, 21: 111-9. PMID: 22332853, DOI: 10.1111/j.1521-0391.2011.00207.x.
  • Physician detection of unhealthy substance use on inpatient teaching and hospitalist medical services.Holt SR, Ramos J, Harma M, Cabrera F, Louis-Ashby C, Dinh A, Fiellin DA, Tetrault JM. Physician detection of unhealthy substance use on inpatient teaching and hospitalist medical services. The American Journal Of Drug And Alcohol Abuse 2013, 39: 121-9. PMID: 22992028, DOI: 10.3109/00952990.2012.715703.
  • Instruments to assess patient-reported safety, efficacy, or misuse of current opioid therapy for chronic pain: a systematic review.Becker WC, Fraenkel L, Edelman EJ, Holt SR, Glover J, Kerns RD, Fiellin DA. Instruments to assess patient-reported safety, efficacy, or misuse of current opioid therapy for chronic pain: a systematic review. Pain 2013, 154: 905-16. PMID: 23601625, PMCID: PMC3683236, DOI: 10.1016/j.pain.2013.02.031.
  • The Addiction Recovery Clinic: A Novel, Primary-Care-Based Approach to Teaching Addiction Medicine.Holt SR, Segar N, Cavallo DA, Tetrault JM. The Addiction Recovery Clinic: A Novel, Primary-Care-Based Approach to Teaching Addiction Medicine. Academic Medicine : Journal Of The Association Of American Medical Colleges 2017, 92: 680-683. PMID: 28441678, DOI: 10.1097/ACM.0000000000001480.
  • Resident and Faculty Perceptions of Chart-Stimulated Recall.Holt SR, Sofair AN. Resident and Faculty Perceptions of Chart-Stimulated Recall. Southern Medical Journal 2017, 110: 142-146. PMID: 28158886, DOI: 10.14423/SMJ.0000000000000600.
  • Strategies for Teaching Physical Diagnosis at the BedsideHolt SR, Moriarty J. “Strategies for Teaching Physical Diagnosis at the Bedside.” Academic Internal Medicine Insight, 2016; 14: 17-19
  • Unhealthy Alcohol Use.Holt S, Tetrault J. Unhealthy Alcohol Use. Clinics In Liver Disease 2016, 20: 429-44. PMID: 27373607, DOI: 10.1016/j.cld.2016.02.003.
  • Caring for patients with opioid use disorder in the hospital.Donroe JH, Holt SR, Tetrault JM. Caring for patients with opioid use disorder in the hospital. CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne 2016, 188: 1232-1239. PMID: 27647616, PMCID: PMC5135493, DOI: 10.1503/cmaj.160290.
  • OSCE-Based Teaching of the Musculoskeletal Exam to Internal Medicine Residents and Medical Students: Neck and SpineSoares S, Wang H, Siddharthan T, Holt S. OSCE-Based Teaching of the Musculoskeletal Exam to Internal Medicine Residents and Medical Students: Neck and Spine. MedEdPORTAL Publications; 2015. Available from: https://www.mededportal.org/publication/10120
  • Interpreting quantitative urine buprenorphine and norbuprenorphine levels in office-based clinical practice.Donroe JH, Holt SR, O'Connor PG, Sukumar N, Tetrault JM. Interpreting quantitative urine buprenorphine and norbuprenorphine levels in office-based clinical practice. Drug And Alcohol Dependence 2017, 180: 46-51. PMID: 28866369, DOI: 10.1016/j.drugalcdep.2017.07.040.
  • Objective Structured Clinical Examination-Based Teaching of the Musculoskeletal Examination.Siddharthan T, Soares S, Wang HH, Holt SR. Objective Structured Clinical Examination-Based Teaching of the Musculoskeletal Examination. Southern Medical Journal 2017, 110: 761-764. PMID: 29197309, DOI: 10.14423/SMJ.0000000000000739.
  • Factors Affecting Resident Satisfaction in Continuity Clinic-a Systematic Review.Stepczynski J, Holt SR, Ellman MS, Tobin D, Doolittle BR. Factors Affecting Resident Satisfaction in Continuity Clinic-a Systematic Review. Journal Of General Internal Medicine 2018, 33: 1386-1393. PMID: 29736753, PMCID: PMC6082200, DOI: 10.1007/s11606-018-4469-8.
  • Efficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial.Edelman EJ, Moore BA, Holt SR, Hansen N, Kyriakides TC, Virata M, Brown ST, Justice AC, Bryant KJ, Fiellin DA, Fiellin LE. Efficacy of Extended-Release Naltrexone on HIV-Related and Drinking Outcomes Among HIV-Positive Patients: A Randomized-Controlled Trial. AIDS And Behavior 2019, 23: 211-221. PMID: 30073637, PMCID: PMC6476298, DOI: 10.1007/s10461-018-2241-z.
  • A scalable, automated warm handoff from the emergency department to community sites offering continued medication for opioid use disorder: Lessons learned from the EMBED trial stakeholders.Ahmed OM, Mao JA, Holt SR, Hawk K, D'Onofrio G, Martel S, Melnick ER. A scalable, automated warm handoff from the emergency department to community sites offering continued medication for opioid use disorder: Lessons learned from the EMBED trial stakeholders. Journal Of Substance Abuse Treatment 2019, 102: 47-52. PMID: 31202288, PMCID: PMC6578846, DOI: 10.1016/j.jsat.2019.05.006.
  • Pharmacotherapy for Alcohol Use Disorder.Holt SR, Tobin DG. Pharmacotherapy for Alcohol Use Disorder. The Medical Clinics Of North America 2018, 102: 653-666. PMID: 29933821, DOI: 10.1016/j.mcna.2018.02.008.
  • Unhealthy Alcohol UseDonroe JH, Holt SR. Unhealthy Alcohol Use. In: Black DW, editor. Psychiatry [online]. Hamilton ON: Decker Medicine; April, 2019. DOI: 10.2310/7800.13106. Available at https://www.deckerip.com/decker/psychiatry/
  • Treatment of Unhealthy Alcohol UseHolt SR, Fiellin, DA. Treatment of Unhealthy Alcohol Use. In: Black DW, editor. Psychiatry [online]. Hamilton ON: Decker Medicine; April, 2019. DOI: 10.2310/7800.13107. Available at https://www.deckerip.com/decker/psychiatry/
  • Physicians Should Play a Role in Ensuring Safe Firearm Ownership.Holt SR, Rosenbaum J, Ellman M, Doolittle B, Tobin DG. Physicians Should Play a Role in Ensuring Safe Firearm Ownership. Journal Of General Internal Medicine 2019, 34: 1637-1640. PMID: 31062224, PMCID: PMC6667526, DOI: 10.1007/s11606-019-05034-2.
  • Addressing discordant quantitative urine buprenorphine and norbuprenorphine levels: Case examples in opioid use disorder.Holt SR, Donroe JH, Cavallo DA, Tetrault JM. Addressing discordant quantitative urine buprenorphine and norbuprenorphine levels: Case examples in opioid use disorder. Drug And Alcohol Dependence 2018, 186: 171-174. PMID: 29579725, DOI: 10.1016/j.drugalcdep.2017.12.040.
  • Ambulatory management of alcohol withdrawalHolt S, Tetrault J. Invited author for Uptodate: "Ambulatory management of alcohol withdrawal." Uptodate.com. Available as of 12/1/2017.
  • Models of Resident Physician Training in Opioid Use DisordersGraddy, R., Accurso, A.J., Nandiwada, D.R. et al. Models of Resident Physician Training in Opioid Use Disorders. Curr Addict Rep 6, 355–364 (2019). https://doi.org/10.1007/s40429-019-00271-1
  • Computerized Cognitive Behavioral Therapy for Substance Use Disorders in a Specialized Primary Care Practice: A Randomized Feasibility Trial to Address the RT Component of SBIRT.Tetrault JM, Holt SR, Cavallo DA, O'Connor PG, Gordon MA, Corvino JK, Nich C, Carroll KM. Computerized Cognitive Behavioral Therapy for Substance Use Disorders in a Specialized Primary Care Practice: A Randomized Feasibility Trial to Address the RT Component of SBIRT. Journal Of Addiction Medicine 2020, 14: e303-e309. PMID: 32371660, DOI: 10.1097/ADM.0000000000000663.
  • Responding to Unsafe Opioid Use: Abandon the Drug, Not the Patient.Tobin DG, Holt SR, Doolittle BR. Responding to Unsafe Opioid Use: Abandon the Drug, Not the Patient. Journal Of General Internal Medicine 2021, 36: 790-791. PMID: 33037590, PMCID: PMC7947064, DOI: 10.1007/s11606-020-06281-4.
  • The Spectrum of Alcohol Use: Epidemiology, Diagnosis, and Treatment.Cohen SM, Alexander RS, Holt SR. The Spectrum of Alcohol Use: Epidemiology, Diagnosis, and Treatment. The Medical Clinics Of North America 2022, 106: 43-60. PMID: 34823734, DOI: 10.1016/j.mcna.2021.08.003.
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