Sravan Perla, PhD, MSc
Associate Research Scientist in Pharmacology
Research & Publications
Biography
Coauthors
Selected Publications
- Identification of Protein Tyrosine Phosphatase (PTP) SubstratesPerla S, Qiu B, Dorry S, Yi J, Bennett A. Identification of Protein Tyrosine Phosphatase (PTP) Substrates. 2023, 2743: 123-133. PMID: 38147212, DOI: 10.1007/978-1-0716-3569-8_8.
- Epigenetic and transcriptional regulation of the human angiotensinogen gene by high saltPerla S, Kumar A. Epigenetic and transcriptional regulation of the human angiotensinogen gene by high salt. BioRxiv 2023 PMID: 38045346, DOI: 10.1101/2023.11.22.568343.
- An Assessment of the Therapeutic Landscape for the Treatment of Heart Disease in the RASopathiesYi JS, Perla S, Bennett AM. An Assessment of the Therapeutic Landscape for the Treatment of Heart Disease in the RASopathies. Cardiovascular Drugs And Therapy 2022, 37: 1193-1204. PMID: 35156148, DOI: 10.1007/s10557-022-07324-0.
- Low-dose Dasatinib Ameliorates Hypertrophic Cardiomyopathy in Noonan Syndrome with Multiple LentiginesYi JS, Perla S, Huang Y, Mizuno K, Giordano FJ, Vinks AA, Bennett AM. Low-dose Dasatinib Ameliorates Hypertrophic Cardiomyopathy in Noonan Syndrome with Multiple Lentigines. Cardiovascular Drugs And Therapy 2021, 36: 589-604. PMID: 33689087, PMCID: PMC9270274, DOI: 10.1007/s10557-021-07169-z.
- Tyrosyl phosphorylation of PZR promotes hypertrophic cardiomyopathy in PTPN11-associated Noonan syndrome with multiple lentiginesYi JS, Perla S, Enyenihi L, Bennett AM. Tyrosyl phosphorylation of PZR promotes hypertrophic cardiomyopathy in PTPN11-associated Noonan syndrome with multiple lentigines. JCI Insight 2020, 5 PMID: 32584792, PMCID: PMC7455087, DOI: 10.1172/jci.insight.137753.
- A polymorphism in intron I of the human angiotensinogen gene (hAGT) affects binding by HNF3 and hAGT expression and increases blood pressure in miceMopidevi B, Kaw MK, Sivankutty I, Jain S, Perla SK, Kumar A. A polymorphism in intron I of the human angiotensinogen gene (hAGT) affects binding by HNF3 and hAGT expression and increases blood pressure in mice. Journal Of Biological Chemistry 2019, 294: 11829-11839. PMID: 31201268, PMCID: PMC6682742, DOI: 10.1074/jbc.ra119.007715.
- Abstract 095: Renal Transcriptomic Analysis of Transgenic Mice Containing Human Cyp11b2 GeneMopidevi B, Sivankutty I, Perla S, Jain S, Kumar A. Abstract 095: Renal Transcriptomic Analysis of Transgenic Mice Containing Human Cyp11b2 Gene. Hypertension 2018, 72 DOI: 10.1161/hyp.72.suppl_1.095.
- Abstract 116: Epigenetic Regulation of Human Angiotensinogen (hAGT) Gene by SNPs.Perla S, Mopidevi B, Sivankutty I, Jain S, Jain K, Kumar A. Abstract 116: Epigenetic Regulation of Human Angiotensinogen (hAGT) Gene by SNPs. Hypertension 2018, 72 DOI: 10.1161/hyp.72.suppl_1.116.
- Abstract P377: Effect of Salt Diet on Haplotype Specific Expression of Human Angiotensinogen GeneSivankutty I, Mopidevi B, Perla S, Jain S, Kumar A. Abstract P377: Effect of Salt Diet on Haplotype Specific Expression of Human Angiotensinogen Gene. Hypertension 2018, 72 DOI: 10.1161/hyp.72.suppl_1.p377.
- Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic MiceJain S, Rana A, Jain K, Perla SK, Puri N, Kumar A. Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice. American Journal Of Hypertension 2018, 31: 1234-1242. PMID: 30084918, PMCID: PMC6454504, DOI: 10.1093/ajh/hpy121.
- Cardiovascular risk markers and thyroid status in young Indian women with polycystic ovarian syndrome: a case-control study.Sravan Kumar P, Ananthanarayanan PH, Rajendiran S. Cardiovascular risk markers and thyroid status in young Indian women with polycystic ovarian syndrome: a case-control study. The Journal Of Obstetrics And Gynaecology Research 2014, 40: 1361-7. PMID: 24750325, DOI: 10.1111/jog.12346.