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Shi-Yi Wang, MD, PhD

Associate Professor of Epidemiology (Chronic Diseases)

Contact Information

Shi-Yi Wang, MD, PhD

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Research Summary

My research endeavor contributes to literature on outcomes research, focusing on breast cancer and end-of-life care. I am leading several breast cancer projects, including an evaluation of preoperative breast MRI, development of an individualized decision aid to help radiotherapy decision-making, and assessment of sentinel lymph node biopsy for patients with ductal carcinoma in situ. I am also working on cost-effectiveness analyses of chemotherapy and genetic profiling, which will facilitate value-based practice. I also conduct research examining end-of-life care intensity, such as patterns of end-of-life care transitions and the associations between hospice use and end-of-life expenditures. Currently, I am serving as the principal investigator for the following two projects:

Title: Comparative modeling of multiple myeloma across myeloma control continuum: prevention, treatment, and disparity reduction

Major Goals: To build natural history modeling for multiple myeloma progression, and evaluate whether promising intervention strategies throughout the continuum of care will prevent the devastating disease or improve survival outcomes

Project/Proposal Start and End Date: 09/2021 – 08/2026

Source of Support: NIH/NCI

Title: Novel conceptual framework for cancer comparative effectiveness research

Major Goals: Using systematic literature review, secondary data analysis, and simulation modeling, we will identify the optimal sequences of treatment for advanced lung cancer

Project/Proposal Start and End Date: 01/2023 – 12/2026

Source of Support: American Cancer Society


Research Interests

Breast Neoplasms; Terminal Care

Public Health Interests

Aging; Cancer; End-of-life Care; Global Health; Health Care Quality, Efficiency; Modeling

Selected Publications