Shiny Nair, PhD
Associate Research Scientist
Research & Publications
Biography
News
Coauthors
Selected Publications
- Nitric oxide inhibits interleukin-12 p40 through p38 MAPK-mediated regulation of calmodulin and c-rel.Boddupalli CS, Ghosh S, Rahim SS, Nair S, Ehtesham NZ, Hasnain SE, Mukhopadhyay S. Nitric oxide inhibits interleukin-12 p40 through p38 MAPK-mediated regulation of calmodulin and c-rel. Free Radical Biology & Medicine 2007, 42: 686-97. PMID: 17291992, DOI: 10.1016/j.freeradbiomed.2006.12.014.
- Association of strong immune responses to PPE protein Rv1168c with active tuberculosis.Khan N, Alam K, Nair S, Valluri VL, Murthy KJ, Mukhopadhyay S. Association of strong immune responses to PPE protein Rv1168c with active tuberculosis. Clinical And Vaccine Immunology : CVI 2008, 15: 974-80. PMID: 18400969, PMCID: PMC2446626, DOI: 10.1128/CVI.00485-07.
- The PPE18 of Mycobacterium tuberculosis interacts with TLR2 and activates IL-10 induction in macrophage.Nair S, Ramaswamy PA, Ghosh S, Joshi DC, Pathak N, Siddiqui I, Sharma P, Hasnain SE, Mande SC, Mukhopadhyay S. The PPE18 of Mycobacterium tuberculosis interacts with TLR2 and activates IL-10 induction in macrophage. Journal Of Immunology (Baltimore, Md. : 1950) 2009, 183: 6269-81. PMID: 19880448, DOI: 10.4049/jimmunol.0901367.
- Glutathione-redox balance regulates c-rel-driven IL-12 production in macrophages: possible implications in antituberculosis immunotherapy.Alam K, Ghousunnissa S, Nair S, Valluri VL, Mukhopadhyay S. Glutathione-redox balance regulates c-rel-driven IL-12 production in macrophages: possible implications in antituberculosis immunotherapy. Journal Of Immunology (Baltimore, Md. : 1950) 2010, 184: 2918-29. PMID: 20164428, DOI: 10.4049/jimmunol.0900439.
- The PPE18 protein of Mycobacterium tuberculosis inhibits NF-κB/rel-mediated proinflammatory cytokine production by upregulating and phosphorylating suppressor of cytokine signaling 3 protein.Nair S, Pandey AD, Mukhopadhyay S. The PPE18 protein of Mycobacterium tuberculosis inhibits NF-κB/rel-mediated proinflammatory cytokine production by upregulating and phosphorylating suppressor of cytokine signaling 3 protein. Journal Of Immunology (Baltimore, Md. : 1950) 2011, 186: 5413-24. PMID: 21451109, DOI: 10.4049/jimmunol.1000773.
- Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targets.Mukhopadhyay S, Nair S, Ghosh S. Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targets. FEMS Microbiology Reviews 2012, 36: 463-85. PMID: 22092372, DOI: 10.1111/j.1574-6976.2011.00302.x.
- Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma.Richter J, Neparidze N, Zhang L, Nair S, Monesmith T, Sundaram R, Miesowicz F, Dhodapkar KM, Dhodapkar MV. Clinical regressions and broad immune activation following combination therapy targeting human NKT cells in myeloma. Blood 2013, 121: 423-30. PMID: 23100308, PMCID: PMC3548165, DOI: 10.1182/blood-2012-06-435503.
- Clonal Immunoglobulin against Lysolipids in the Origin of Myeloma.Nair S, Branagan AR, Liu J, Boddupalli CS, Mistry PK, Dhodapkar MV. Clonal Immunoglobulin against Lysolipids in the Origin of Myeloma. The New England Journal Of Medicine 2016, 374: 555-61. PMID: 26863356, PMCID: PMC4804194, DOI: 10.1056/NEJMoa1508808.
- ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells.Boddupalli CS, Nair S, Gray SM, Nowyhed HN, Verma R, Gibson JA, Abraham C, Narayan D, Vasquez J, Hedrick CC, Flavell RA, Dhodapkar KM, Kaech SM, Dhodapkar MV. ABC transporters and NR4A1 identify a quiescent subset of tissue-resident memory T cells. The Journal Of Clinical Investigation 2016, 126: 3905-3916. PMID: 27617863, PMCID: PMC5096804, DOI: 10.1172/JCI85329.
- Natural Killer T Cells in Cancer Immunotherapy.Nair S, Dhodapkar MV. Natural Killer T Cells in Cancer Immunotherapy. Frontiers In Immunology 2017, 8: 1178. PMID: 29018445, PMCID: PMC5614937, DOI: 10.3389/fimmu.2017.01178.
- Antigen-mediated regulation in monoclonal gammopathies and myeloma.Nair S, Sng J, Boddupalli CS, Seckinger A, Chesi M, Fulciniti M, Zhang L, Rauniyar N, Lopez M, Neparidze N, Parker T, Munshi NC, Sexton R, Barlogie B, Orlowski R, Bergsagel L, Hose D, Flavell RA, Mistry PK, Meffre E, Dhodapkar MV. Antigen-mediated regulation in monoclonal gammopathies and myeloma. JCI Insight 2018, 3 PMID: 29669929, PMCID: PMC5931125, DOI: 10.1172/jci.insight.98259.
- Glucosylsphingosine but not Saposin C, is the target antigen in Gaucher disease-associated gammopathy.Nair S, Bar N, Xu ML, Dhodapkar M, Mistry PK. Glucosylsphingosine but not Saposin C, is the target antigen in Gaucher disease-associated gammopathy. Molecular Genetics And Metabolism 2020, 129: 286-291. PMID: 32044242, PMCID: PMC8223251, DOI: 10.1016/j.ymgme.2020.01.009.
- Type II NKT-TFH cells against Gaucher lipids regulate B-cell immunity and inflammation.Nair S, Boddupalli CS, Verma R, Liu J, Yang R, Pastores GM, Mistry PK, Dhodapkar MV. Type II NKT-TFH cells against Gaucher lipids regulate B-cell immunity and inflammation. Blood 2015, 125: 1256-71. PMID: 25499455, PMCID: PMC4335081, DOI: 10.1182/blood-2014-09-600270.
- Endocytosis of Mycobacterium tuberculosis heat shock protein 60 is required to induce interleukin-10 production in macrophages.Parveen N, Varman R, Nair S, Das G, Ghosh S, Mukhopadhyay S. Endocytosis of Mycobacterium tuberculosis heat shock protein 60 is required to induce interleukin-10 production in macrophages. The Journal Of Biological Chemistry 2013, 288: 24956-71. PMID: 23846686, PMCID: PMC3750191, DOI: 10.1074/jbc.M113.461004.
- The clinical spectrum of SARS-CoV-2 infection in Gaucher disease: Effect of both a pandemic and a rare disease that disrupts the immune system.Narayanan P, Nair S, Balwani M, Malinis M, Mistry P. The clinical spectrum of SARS-CoV-2 infection in Gaucher disease: Effect of both a pandemic and a rare disease that disrupts the immune system. Molecular Genetics And Metabolism 2022, 135: 115-121. PMID: 34412940, PMCID: PMC8361210, DOI: 10.1016/j.ymgme.2021.08.004.