Shamsuddin Akhtar, MD

• Amit Bardia
• Cassius Iyad Ochoa Chaar
• Christopher Howes
• David Silverman
• David Yanez
• Elaine Fajardo
• Elena Gutman
• George Tellides
• Hossam Tantawy
• Jeptha Curtis
• John Elefteriades
• Jordan Pober
• Joseph Zinter
• Laura Niklason
• Linda Maerz
• Matthew Burg
• Mihaela Aslan
• Natalie Holt
• Paul Heerdt
• Ranjit Deshpande
• Robert Schonberger
• Silvio Inzucchi
• Stanley Rosenbaum
• Steven Pfau

Anesthesiology; Pharmacology; Perioperative Care; Critical Care Outcomes

• Significance of beta-blockers in the perioperative period.Akhtar S, Barash PG. Significance of beta-blockers in the perioperative period. Current Opinion In Anaesthesiology 2002, 15: 27-35. PMID: 17019181, DOI: 10.1097/00001503-200202000-00005.
• Assessment and management of patients with ischemic heart disease.Akhtar S, Silverman DG. Assessment and management of patients with ischemic heart disease. Critical Care Medicine 2004, 32: S126-36. PMID: 15064671.
• Preoperative beta-blocker use: is titration to a heart rate of 60 beats per minute a consistently attainable goal?Akhtar S, Amin M, Tantawy H, Senior A, Barash PG, Silverman DG. Preoperative beta-blocker use: is titration to a heart rate of 60 beats per minute a consistently attainable goal? Journal Of Clinical Anesthesia 2005, 17: 191-7. PMID: 15896586, DOI: 10.1016/j.jclinane.2004.06.020.
• Heparin displaces interferon-gamma-inducible chemokines (IP-10, I-TAC, and Mig) sequestered in the vasculature and inhibits the transendothelial migration and arterial recruitment of T cells.Ranjbaran H, Wang Y, Manes TD, Yakimov AO, Akhtar S, Kluger MS, Pober JS, Tellides G. Heparin displaces interferon-gamma-inducible chemokines (IP-10, I-TAC, and Mig) sequestered in the vasculature and inhibits the transendothelial migration and arterial recruitment of T cells. Circulation 2006, 114: 1293-300. PMID: 16940188, DOI: 10.1161/CIRCULATIONAHA.106.631457.
• Ischemic heart disease.Akhtar S. Ischemic heart disease. Anesthesiology Clinics 2006, 24: 461-85. PMID: 17240602, DOI: 10.1016/j.atc.2006.04.002.
• An inflammatory pathway of IFN-gamma production in coronary atherosclerosis.Ranjbaran H, Sokol SI, Gallo A, Eid RE, Iakimov AO, D'Alessio A, Kapoor JR, Akhtar S, Howes CJ, Aslan M, Pfau S, Pober JS, Tellides G. An inflammatory pathway of IFN-gamma production in coronary atherosclerosis. Journal Of Immunology (Baltimore, Md. : 1950) 2007, 178: 592-604. PMID: 17182600, DOI: 10.4049/jimmunol.178.1.592.
• Survey of anesthesiologists as to the value of prior ECG in a patient with nonspecific ST-T wave changes.Tantawy H, Silverman TJ, Silverman DG, Akhtar S. Survey of anesthesiologists as to the value of prior ECG in a patient with nonspecific ST-T wave changes. Connecticut Medicine 2007, 71: 453-6. PMID: 17902381.
• Preoperative beta-blocker use: impact of national guidelines on clinical practice.Akhtar S, Assaad S, Amin M, Holt NF, Barash PG, Silverman DG. Preoperative beta-blocker use: impact of national guidelines on clinical practice. Journal Of Clinical Anesthesia 2008, 20: 122-8. PMID: 18410867, DOI: 10.1016/j.jclinane.2007.09.012.
• Fat embolism.Akhtar S. Fat embolism. Anesthesiology Clinics 2009, 27: 533-50, table of contents. PMID: 19825491, DOI: 10.1016/j.anclin.2009.07.018.
• Scientific principles and clinical implications of perioperative glucose regulation and control.Akhtar S, Barash PG, Inzucchi SE. Scientific principles and clinical implications of perioperative glucose regulation and control. Anesthesia And Analgesia 2010, 110: 478-97. PMID: 20081134, DOI: 10.1213/ANE.0b013e3181c6be63.
• How sweet it is . . . (or isn't)!Peterfreund RA, Akhtar S. How sweet it is . . . (or isn't)! Anesthesia And Analgesia 2010, 110: 979-81. PMID: 20357141, DOI: 10.1213/ANE.0b013e3181d4527e.
• Perioperative glycemic management in 2011: paradigm shifts.Maerz LL, Akhtar S. Perioperative glycemic management in 2011: paradigm shifts. Current Opinion In Critical Care 2011, 17: 370-5. PMID: 21734491, DOI: 10.1097/MCC.0b013e328348beb7.
• Creating a perioperative glycemic control program.Alexanian SM, McDonnell ME, Akhtar S. Creating a perioperative glycemic control program. Anesthesiology Research And Practice 2011, 2011: 465974. PMID: 21912542, PMCID: PMC3168770, DOI: 10.1155/2011/465974.
• Utility of ultrasound in the ICU.Deshpande R, Akhtar S, Haddadin AS. Utility of ultrasound in the ICU. Current Opinion In Anaesthesiology 2014, 27: 123-32. PMID: 24589673, DOI: 10.1097/ACO.0000000000000057.
• Guidelines and perioperative care of the elderly.Akhtar S. Guidelines and perioperative care of the elderly. International Anesthesiology Clinics 2014, 52: 64-76. PMID: 25268865, DOI: 10.1097/AIA.0000000000000033.
• Case 3-2015: preventing adverse outcomes in the very elderly cardiac surgical patients.Akhtar S, Morris B, Roy R, Balogun SA. Case 3-2015: preventing adverse outcomes in the very elderly cardiac surgical patients. Journal Of Cardiothoracic And Vascular Anesthesia 2015, 29: 510-21. PMID: 25440648, DOI: 10.1053/j.jvca.2014.07.014.
• Geriatric Pharmacology.Akhtar S, Ramani R. Geriatric Pharmacology. Anesthesiology Clinics 2015, 33: 457-69. PMID: 26315631, DOI: 10.1016/j.anclin.2015.05.004.
• A Retrospective Observational Study of Anesthetic Induction Dosing Practices in Female Elderly Surgical Patients: Are We Overdosing Older Patients?Akhtar S, Heng J, Dai F, Schonberger RB, Burg MM. A Retrospective Observational Study of Anesthetic Induction Dosing Practices in Female Elderly Surgical Patients: Are We Overdosing Older Patients? Drugs & Aging 2016, 33: 737-746. PMID: 27581549, DOI: 10.1007/s40266-016-0394-x.
• Does intravenous induction dosing among patients undergoing gastrointestinal surgical procedures follow current recommendations: a study of contemporary practice.Akhtar S, Liu J, Heng J, Dai F, Schonberger RB, Burg MM. Does intravenous induction dosing among patients undergoing gastrointestinal surgical procedures follow current recommendations: a study of contemporary practice. Journal Of Clinical Anesthesia 2016, 33: 208-15. PMID: 27555166, DOI: 10.1016/j.jclinane.2016.02.001.
• Pharmacological considerations in the elderly.Akhtar S. Pharmacological considerations in the elderly. Current Opinion In Anaesthesiology 2018, 31: 11-18. PMID: 29189287, DOI: 10.1097/ACO.0000000000000544.
• Association of red blood cell transfusion and short- and longer-term mortality after coronary artery bypass graft surgery.Tantawy H, Li A, Dai F, Elgammal M, Sukumar N, Elefteriades J, Akhtar S. Association of red blood cell transfusion and short- and longer-term mortality after coronary artery bypass graft surgery. Journal Of Cardiothoracic And Vascular Anesthesia 2018, 32: 1225-1232. PMID: 29402623, DOI: 10.1053/j.jvca.2017.12.033.
• A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General Anesthesia.Chen EY, Sukumar N, Dai F, Akhtar S, Schonberger RB. A Pilot Analysis of the Association Between Types of Monitored Anesthesia Care Drugs and Outcomes in Transfemoral Aortic Valve Replacement Performed Without General Anesthesia. Journal Of Cardiothoracic And Vascular Anesthesia 2018, 32: 666-671. PMID: 29277298, PMCID: PMC5766429, DOI: 10.1053/j.jvca.2017.07.009.
• Safety of 4-factor prothrombin complex concentrate (4F-PCC) for emergent reversal of factor Xa inhibitors.Tao J, Bukanova EN, Akhtar S. Safety of 4-factor prothrombin complex concentrate (4F-PCC) for emergent reversal of factor Xa inhibitors. Journal Of Intensive Care 2018, 6: 34. PMID: 29942519, PMCID: PMC6001072, DOI: 10.1186/s40560-018-0303-y.
• Intermittent cardiac troponin-I screening is an effective means of surveillance for a perioperative myocardial infarction.Martinez EA, Nass CM, Jermyn RM, Rosenbaum SH, Akhtar S, Chan DW, Malkus H, Weiss JL, Fleisher LA. Intermittent cardiac troponin-I screening is an effective means of surveillance for a perioperative myocardial infarction. Journal Of Cardiothoracic And Vascular Anesthesia 2005, 19: 577-82. PMID: 16202889, DOI: 10.1053/j.jvca.2005.07.002.
• Perioperative use of beta-blockers: past, present, and future.Akhtar S, Barash PG. Perioperative use of beta-blockers: past, present, and future. International Anesthesiology Clinics 2002, 40: 133-57. PMID: 11897941.
• Coronary stents: factors contributing to perioperative major adverse cardiovascular events.Barash P, Akhtar S. Coronary stents: factors contributing to perioperative major adverse cardiovascular events. British Journal Of Anaesthesia 2010, 105 Suppl 1: i3-15. PMID: 21148653, DOI: 10.1093/bja/aeq318.
• An Analysis of Anesthesia Induction Dosing in Female Older Adults.Chen EY, Michel G, Zhou B, Dai F, Akhtar S, Schonberger RB. An Analysis of Anesthesia Induction Dosing in Female Older Adults. Drugs & Aging 2020, 37: 435-446. PMID: 32300966, PMCID: PMC7359723, DOI: 10.1007/s40266-020-00760-3.
• Regional Anesthesia is Underutilized for Carotid Endarterectomy Despite Improved Perioperative Outcomes Compared with General Anesthesia.Lumas S, Hsiang W, Akhtar S, Ochoa Chaar CI. Regional Anesthesia is Underutilized for Carotid Endarterectomy Despite Improved Perioperative Outcomes Compared with General Anesthesia. Annals Of Vascular Surgery 2021, 73: 336-343. PMID: 33373769, DOI: 10.1016/j.avsg.2020.11.035.
• Variation in propofol induction doses administered to surgical patients over age 65.Schonberger RB, Bardia A, Dai F, Michel G, Yanez D, Curtis JP, Vaughn MT, Burg MM, Mathis M, Kheterpal S, Akhtar S, Shah N. Variation in propofol induction doses administered to surgical patients over age 65. Journal Of The American Geriatrics Society 2021, 69: 2195-2209. PMID: 33788251, PMCID: PMC8373684, DOI: 10.1111/jgs.17139.
• Reply to: Comment on: Variation in propofol induction doses administered to surgical patients over 65.Akhtar S, Bardia A, Schonberger RB. Reply to: Comment on: Variation in propofol induction doses administered to surgical patients over 65. Journal Of The American Geriatrics Society 2021, 69: 2680-2681. PMID: 34185888, PMCID: PMC8440365, DOI: 10.1111/jgs.17327.
• Preoperative evaluation of geriatric patients undergoing liver transplantation.Akhtar S. Preoperative evaluation of geriatric patients undergoing liver transplantation. Current Opinion In Anaesthesiology 2022, 35: 96-104. PMID: 34878418, DOI: 10.1097/ACO.0000000000001084.
• Pressure-Regulated Ventilator Splitting for Disaster Relief: Design, Testing, and Clinical Experience.Raredon MSB, Fisher C, Heerdt PM, Schonberger RB, Nargi A, Nivison S, Fajardo E, Deshpande R, Akhtar S, Greaney AM, Belter J, Raredon T, Zinter J, McKee A, Michalski M, Baevova P, Niklason LE. Pressure-Regulated Ventilator Splitting for Disaster Relief: Design, Testing, and Clinical Experience. Anesthesia And Analgesia 2022, 134: 1094-1105. PMID: 34928890, DOI: 10.1213/ANE.0000000000005825.
• Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65.Schonberger RB, Dai F, Michel G, Vaughn MT, Burg MM, Mathis M, Kheterpal S, Akhtar S, Shah N, Bardia A. Association of propofol induction dose and severe pre-incision hypotension among surgical patients over age 65. Journal Of Clinical Anesthesia 2022, 80: 110846. PMID: 35489305, DOI: 10.1016/j.jclinane.2022.110846.
• Relationship Between Glucose Time in Range in Diabetic and Non-Diabetic Patients and Mortality in Critically Ill Patients.Ammar MA, Ammar AA, Wee T, Deshpande R, Band M, Akhtar S. Relationship Between Glucose Time in Range in Diabetic and Non-Diabetic Patients and Mortality in Critically Ill Patients. Journal Of Intensive Care Medicine 2022, 8850666221098383. PMID: 35491687, DOI: 10.1177/08850666221098383.