Sean Gu, MD/PhD
Clinical Fellow; PGY-3, Pathology
Research & Publications
Biography
News
Coauthors
Selected Publications
- Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation.Gu SX, Tyagi T, Jain K, Gu VW, Lee SH, Hwa JM, Kwan JM, Krause DS, Lee AI, Halene S, Martin KA, Chun HJ, Hwa J. Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation. Nature Reviews. Cardiology 2021, 18:194-209.
- Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia.Gu SX, Sonkar VK, Katare PB, Kumar R, Kruger WD, Arning E, Bottiglieri T, Lentz SR, Dayal S. Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia. Journal Of The American Heart Association 2020, 9:e013368.
- Inflammation mediated platelet hyperactivity in aging.Gu SX, Dayal S. Inflammation mediated platelet hyperactivity in aging. Annals Of Blood 2020, 5.
- Fibrin films: overlooked hemostatic barriers against microbial infiltration.Gu SX, Lentz SR. Fibrin films: overlooked hemostatic barriers against microbial infiltration. The Journal Of Clinical Investigation 2018, 128:3243-3245.
- Targeting platelet EPCR for better therapeutic factor VIIa activity.Gu SX, Lentz SR. Targeting platelet EPCR for better therapeutic factor VIIa activity. Journal Of Thrombosis And Haemostasis : JTH 2018, 16:1814-1816.
- Whole-exome sequencing in evaluation of patients with venous thromboembolism.Lee EJ, Dykas DJ, Leavitt AD, Camire RM, Ebberink E, García de Frutos P, Gnanasambandan K, Gu SX, Huntington JA, Lentz SR, Mertens K, Parish CR, Rezaie AR, Sayeski PP, Cromwell C, Bar N, Halene S, Neparidze N, Parker TL, Burns AJ, Dumont A, Yao X, Chaar CIO, Connors JM, Bale AE, Lee AI. Whole-exome sequencing in evaluation of patients with venous thromboembolism. Blood Advances 2017, 1:1224-1237.
- Protein methionine oxidation augments reperfusion injury in acute ischemic stroke.Gu SX, Blokhin IO, Wilson KM, Dhanesha N, Doddapattar P, Grumbach IM, Chauhan AK, Lentz SR. Protein methionine oxidation augments reperfusion injury in acute ischemic stroke. JCI Insight 2016, 1.
- Regulation of thrombosis and vascular function by protein methionine oxidation.Gu SX, Stevens JW, Lentz SR. Regulation of thrombosis and vascular function by protein methionine oxidation. Blood 2015, 125:3851-9.
- Deficiency of superoxide dismutase impairs protein C activation and enhances susceptibility to experimental thrombosis.Dayal S, Gu SX, Hutchins RD, Wilson KM, Wang Y, Fu X, Lentz SR. Deficiency of superoxide dismutase impairs protein C activation and enhances susceptibility to experimental thrombosis. Arteriosclerosis, Thrombosis, And Vascular Biology 2015, 35:1798-804.
- Deletion of Methionine Sulfoxide Reductase A Does Not Affect Atherothrombosis but Promotes Neointimal Hyperplasia and Extracellular Signal-Regulated Kinase 1/2 Signaling.Klutho PJ, Pennington SM, Scott JA, Wilson KM, Gu SX, Doddapattar P, Xie L, Venema AN, Zhu LJ, Chauhan AK, Lentz SR, Grumbach IM. Deletion of Methionine Sulfoxide Reductase A Does Not Affect Atherothrombosis but Promotes Neointimal Hyperplasia and Extracellular Signal-Regulated Kinase 1/2 Signaling. Arteriosclerosis, Thrombosis, And Vascular Biology 2015, 35:2594-604.
- Transport kinetics and selectivity of HpUreI, the urea channel from Helicobacter pylori.Gray LR, Gu SX, Quick M, Khademi S. Transport kinetics and selectivity of HpUreI, the urea channel from Helicobacter pylori. Biochemistry 2011, 50:8656-63.
- Supramolecular catalysis in the organic solid state through dry grinding.Sokolov AN, Bucar DK, Baltrusaitis J, Gu SX, MacGillivray LR. Supramolecular catalysis in the organic solid state through dry grinding. Angewandte Chemie (International Ed. In English) 2010, 49:4273-7.