Sarah N. Taylor, MD, MSCR
Research & Publications
Biography
News
Research Summary
Dr. Taylor's research centers on infant nutrition and growth with a special focus on human milk and lactation. She explores the behavioral and biologic influences on maternal milk production including methods to mitigate disparities. She investigates preterm infant gut health and development as related to nutritional exposures.
Extensive Research Description
Dr. Taylor and the Yale NOURISH Team (Yale Neonatal Nutrition Outcomes Research In Sustaining mother and infant Health) studies health outcomes affected by pregnancy and lactation and specifically focuses on the mother/infant lactation experience and infant growth and development especially in the setting of growth restriction or prematurity. A sample of our current research:
Human milk feeding is associated with improved gastrointestinal health for preterm infants. We are investigating how the gut barrier and the gut inflammation is affected by early feeding versus delayed feeding and feeding mother’s milk or donor milk
Human milk, either mother’s own milk or donor human milk, varies in its nutritional composition. We use a mid-infrared human milk analyzer to investigate the energy and protein in human milk and correlate these results with infant health outcomes.
Woman with diabetes during pregnancy are more likely to experience lactation difficulties. We are studying the factors associated with maternal lactation choices and maternal experience to determine which factors serve as impediments to breastfeeding.
The Neonatal Intensive Care Unit at YNHH is one of the first hospitals in the United States to have couplet care rooms where an infant receiving intensive care and a mother receiving postpartum care share a hospital room. We are investigating how to optimize the couplet care experience to support breastfeeding, bonding, satisfaction and avoid stress.
Infant growth trajectory is affected by exposure to maternal hormones both in fetal development and during lactation. We aim to determine the role of these hormones and how fetal/infant exposures differ due to maternal health.
Coauthors
Research Interests
Intensive Care Units, Neonatal; Milk, Human; Nutritional Requirements; Pediatrics
Selected Publications
- Breastfeeding Initiation as Related to the Interaction of Race/Ethnicity and Maternal Diabetes.Stevens DR, Taylor SN, Roberts JR, Neelon B, Newman RB, Vena JE, Hunt KJ. Breastfeeding Initiation as Related to the Interaction of Race/Ethnicity and Maternal Diabetes. Breastfeeding Medicine : The Official Journal Of The Academy Of Breastfeeding Medicine 2019, 14: 630-639. PMID: 31364862, PMCID: PMC6857546, DOI: 10.1089/bfm.2019.0065.
- Investigation of a Common Clinical Approach to Poor Growth in Preterm Infants.Korff SG, Ross J, Morella K, Taylor SN. Investigation of a Common Clinical Approach to Poor Growth in Preterm Infants. American Journal Of Perinatology 2020, 37: 1462-1466. PMID: 31430817, DOI: 10.1055/s-0039-1694724.
- Preterm infant body composition cannot be accurately determined by weight and length.Kiger JR, Taylor SN, Wagner CL, Finch C, Katikaneni L. Preterm infant body composition cannot be accurately determined by weight and length. Journal Of Neonatal-perinatal Medicine 2016, 9: 285-90. PMID: 27589548, DOI: 10.3233/NPM-16915125.
- Mediation of the association between maternal pre-pregnancy overweight/obesity and childhood overweight/obesity by birth anthropometry.Stevens DR, Neelon B, Roberts JR, Taylor SN, Newman RB, Vena JE, Hunt KJ. Mediation of the association between maternal pre-pregnancy overweight/obesity and childhood overweight/obesity by birth anthropometry. Journal Of Developmental Origins Of Health And Disease 2021, 12: 71-78. PMID: 32077839, PMCID: PMC7438242, DOI: 10.1017/S2040174420000033.
- Growth in the High-Risk Newborn Infant Post-Discharge: Results from a Neonatal Intensive Care Unit Nutrition Follow-up Clinic.Zhang X, Donnelly B, Thomas J, Sams L, O'Brien K, Taylor SN, Jump CS. Growth in the High-Risk Newborn Infant Post-Discharge: Results from a Neonatal Intensive Care Unit Nutrition Follow-up Clinic. Nutrition In Clinical Practice : Official Publication Of The American Society For Parenteral And Enteral Nutrition 2020, 35: 738-744. PMID: 32083342, DOI: 10.1002/ncp.10455.
- "Extrauterine growth restriction" and "postnatal growth failure" are misnomers for preterm infants.Fenton TR, Cormack B, Goldberg D, Nasser R, Alshaikh B, Eliasziw M, Hay WW, Hoyos A, Anderson D, Bloomfield F, Griffin I, Embleton N, Rochow N, Taylor S, Senterre T, Schanler RJ, Elmrayed S, Groh-Wargo S, Adamkin D, Shah PS. "Extrauterine growth restriction" and "postnatal growth failure" are misnomers for preterm infants. Journal Of Perinatology : Official Journal Of The California Perinatal Association 2020, 40: 704-714. PMID: 32214217, DOI: 10.1038/s41372-020-0658-5.
- Neonatal vitamin D status at birth at latitude 32 degrees 72': evidence of deficiency.Basile LA, Taylor SN, Wagner CL, Quinones L, Hollis BW. Neonatal vitamin D status at birth at latitude 32 degrees 72': evidence of deficiency. Journal Of Perinatology : Official Journal Of The California Perinatal Association 2007, 27: 568-71. PMID: 17625571, DOI: 10.1038/sj.jp.7211796.
- Refeeding syndrome in very-low-birth-weight intrauterine growth-restricted neonates.Ross JR, Finch C, Ebeling M, Taylor SN. Refeeding syndrome in very-low-birth-weight intrauterine growth-restricted neonates. Journal Of Perinatology : Official Journal Of The California Perinatal Association 2013, 33: 717-20. PMID: 23538644, DOI: 10.1038/jp.2013.28.
- Parent and Provider Perspectives on the Imprecise Label of "Human Milk Fortifier" in the NICU.Canvasser J, Hair AB, Kim JH, Taylor SN. Parent and Provider Perspectives on the Imprecise Label of "Human Milk Fortifier" in the NICU. Nutrients 2020, 12 PMID: 32182782, PMCID: PMC7146547, DOI: 10.3390/nu12030720.
- Factors in Early Feeding Practices That May Influence Growth and the Challenges that Arise in Growth Outcomes Research.Fabrizio V, Shabanova V, Taylor SN. Factors in Early Feeding Practices That May Influence Growth and the Challenges that Arise in Growth Outcomes Research. Nutrients 2020, 12 PMID: 32629763, PMCID: PMC7399918, DOI: 10.3390/nu12071939.
- Human milk fortification: the clinician and parent perspectives.Hair AB, Ferguson J, Grogan C, Kim JH, Taylor SN. Human milk fortification: the clinician and parent perspectives. Pediatric Research 2020, 88: 25-29. PMID: 32855509, DOI: 10.1038/s41390-020-1076-2.
- Safety Aspects of a Randomized Clinical Trial of Maternal and Infant Vitamin D Supplementation by Feeding Type Through 7 Months Postpartum.Wagner CL, Hulsey TC, Ebeling M, Shary JR, Asghari G, Howard CR, Baatz JE, Newton DA, Wahlquist AE, Reed SG, Taylor SN, Lawrence RA, Hollis BW. Safety Aspects of a Randomized Clinical Trial of Maternal and Infant Vitamin D Supplementation by Feeding Type Through 7 Months Postpartum. Breastfeeding Medicine : The Official Journal Of The Academy Of Breastfeeding Medicine 2020, 15: 765-775. PMID: 32915638, PMCID: PMC7757584, DOI: 10.1089/bfm.2020.0056.
- Vitamin D status as related to race and feeding type in preterm infants.Taylor SN, Wagner CL, Fanning D, Quinones L, Hollis BW. Vitamin D status as related to race and feeding type in preterm infants. Breastfeeding Medicine : The Official Journal Of The Academy Of Breastfeeding Medicine 2006, 1: 156-63. PMID: 17661592, DOI: 10.1089/bfm.2006.1.156.
- The effect of high-dose vitamin D supplementation on serum vitamin D levels and milk calcium concentration in lactating women and their infants.Basile LA, Taylor SN, Wagner CL, Horst RL, Hollis BW. The effect of high-dose vitamin D supplementation on serum vitamin D levels and milk calcium concentration in lactating women and their infants. Breastfeeding Medicine : The Official Journal Of The Academy Of Breastfeeding Medicine 2006, 1: 27-35. PMID: 17661558, DOI: 10.1089/bfm.2006.1.27.
- Intestinal permeability in preterm infants by feeding type: mother's milk versus formula.Taylor SN, Basile LA, Ebeling M, Wagner CL. Intestinal permeability in preterm infants by feeding type: mother's milk versus formula. Breastfeeding Medicine : The Official Journal Of The Academy Of Breastfeeding Medicine 2009, 4: 11-5. PMID: 19196035, PMCID: PMC2932544, DOI: 10.1089/bfm.2008.0114.
- Early enteral feeding in very low birth weight infants.Hamilton E, Massey C, Ross J, Taylor S. Early enteral feeding in very low birth weight infants. Early Human Development 2014, 90: 227-30. PMID: 24612934, DOI: 10.1016/j.earlhumdev.2014.02.005.
- The Impact in the United States of the Baby-Friendly Hospital Initiative on Early Infant Health and Breastfeeding Outcomes.Munn AC, Newman SD, Mueller M, Phillips SM, Taylor SN. The Impact in the United States of the Baby-Friendly Hospital Initiative on Early Infant Health and Breastfeeding Outcomes. Breastfeeding Medicine : The Official Journal Of The Academy Of Breastfeeding Medicine 2016, 11: 222-30. PMID: 27082284, PMCID: PMC4921952, DOI: 10.1089/bfm.2015.0135.
- Functional indicators of vitamin D adequacy for very low birth weight infants.Taylor SN, Wahlquist A, Wagner CL, Ramakrishnan V, Ebeling M, Hollis BW. Functional indicators of vitamin D adequacy for very low birth weight infants. Journal Of Perinatology : Official Journal Of The California Perinatal Association 2018, 38: 550-556. PMID: 29743660, PMCID: PMC6382072, DOI: 10.1038/s41372-018-0098-7.
- ABM Clinical Protocol #29: Iron, Zinc, and Vitamin D Supplementation During Breastfeeding.Taylor SN. ABM Clinical Protocol #29: Iron, Zinc, and Vitamin D Supplementation During Breastfeeding. Breastfeeding Medicine : The Official Journal Of The Academy Of Breastfeeding Medicine 2018, 13: 398-404. PMID: 30016173, DOI: 10.1089/bfm.2018.29095.snt.
- Neonatal Extracorporeal Life Support: A Review of Nutrition Considerations.Murphy HJ, Finch CW, Taylor SN. Neonatal Extracorporeal Life Support: A Review of Nutrition Considerations. Nutrition In Clinical Practice : Official Publication Of The American Society For Parenteral And Enteral Nutrition 2018, 33: 625-632. PMID: 30004582, DOI: 10.1002/ncp.10111.
- Factors Influencing Southeastern U.S. Mothers' Participation in Baby-Friendly Practices: A Mixed-Methods Study.Munn AC, Newman SD, Phillips SM, Mueller M, Taylor SN. Factors Influencing Southeastern U.S. Mothers' Participation in Baby-Friendly Practices: A Mixed-Methods Study. Journal Of Human Lactation : Official Journal Of International Lactation Consultant Association 2018, 34: 821-834. PMID: 29432703, DOI: 10.1177/0890334417750143.
- Very low birth weight infants receive full enteral nutrition within 2 postnatal weeks.Fenin A, Newman JC, Taylor SN. Very low birth weight infants receive full enteral nutrition within 2 postnatal weeks. Journal Of Perinatology : Official Journal Of The California Perinatal Association 2020, 40: 1849-1856. PMID: 32994536, PMCID: PMC7522453, DOI: 10.1038/s41372-020-00819-4.
- Concentrating human milk: an innovative point-of-care device designed to increase human milk feeding options for preterm infants.Schinkel ER, Nelson ER, Young BE, Bernstein RM, Taylor SN, Brown LD, Hay WW, Brown KJ, Prenni J. Concentrating human milk: an innovative point-of-care device designed to increase human milk feeding options for preterm infants. Journal Of Perinatology : Official Journal Of The California Perinatal Association 2021, 41: 582-589. PMID: 33060780, DOI: 10.1038/s41372-020-00820-x.
- Vitamin D in Toddlers, Preschool Children, and Adolescents.Taylor SN. Vitamin D in Toddlers, Preschool Children, and Adolescents. Annals Of Nutrition & Metabolism 2020, 76 Suppl 2: 30-41. PMID: 33232959, DOI: 10.1159/000505635.
- Empowering mothers to realize their choice for infant feeding.Taylor SN. Empowering mothers to realize their choice for infant feeding. Seminars In Perinatology 2021, 45: 151379. PMID: 33422329, DOI: 10.1016/j.semperi.2020.151379.
- Barriers and benefits to breastfeeding with gestational diabetes.Doughty K, Taylor SN. Barriers and benefits to breastfeeding with gestational diabetes. Seminars In Perinatology 2021, 45: 151385. PMID: 33446343, DOI: 10.1016/j.semperi.2020.151385.
- Effect of Enteral Protein Amount on Growth and Health Outcomes in Very-Low-Birth-Weight Preterm Infants: Phase II of the Pre-B Project and an Evidence Analysis Center Systematic Review.Fenton TR, Groh-Wargo S, Gura K, Martin CR, Taylor SN, Griffin IJ, Rozga M, Moloney L. Effect of Enteral Protein Amount on Growth and Health Outcomes in Very-Low-Birth-Weight Preterm Infants: Phase II of the Pre-B Project and an Evidence Analysis Center Systematic Review. Journal Of The Academy Of Nutrition And Dietetics 2020 PMID: 33358688, DOI: 10.1016/j.jand.2020.11.002.
- The Impact of 2 Weight-Based Standard Parenteral Nutrition Formulations Compared With One Standard Formulation on the Incidence of Hyperglycemia and Hypernatremia in Low Birth-Weight Preterm Infants.Garner SS, Cox TH, Safirstein J, Groat EK, Breznak K, Taylor SN. The Impact of 2 Weight-Based Standard Parenteral Nutrition Formulations Compared With One Standard Formulation on the Incidence of Hyperglycemia and Hypernatremia in Low Birth-Weight Preterm Infants. Advances In Neonatal Care : Official Journal Of The National Association Of Neonatal Nurses 2021, 21: E65-E72. PMID: 33427753, DOI: 10.1097/ANC.0000000000000806.
- Racial Disparities in Sustaining Breastfeeding in a Baby-Friendly Designated Southeastern United States Hospital: An Opportunity to Investigate Systemic Racism.Hemingway S, Forson-Dare Z, Ebeling M, Taylor SN. Racial Disparities in Sustaining Breastfeeding in a Baby-Friendly Designated Southeastern United States Hospital: An Opportunity to Investigate Systemic Racism. Breastfeeding Medicine : The Official Journal Of The Academy Of Breastfeeding Medicine 2021, 16: 150-155. PMID: 33539272, DOI: 10.1089/bfm.2020.0306.
- Very Low Birthweight Preterm Infants: A 2020 Evidence Analysis Center Evidence-Based Nutrition Practice Guideline.Fenton TR, Griffin IJ, Groh-Wargo S, Gura K, Martin CR, Taylor SN, Rozga M, Moloney L. Very Low Birthweight Preterm Infants: A 2020 Evidence Analysis Center Evidence-Based Nutrition Practice Guideline. Journal Of The Academy Of Nutrition And Dietetics 2022, 122: 182-206. PMID: 33820749, DOI: 10.1016/j.jand.2021.02.027.
- The Nutritional Composition and Energy Content of Donor Human Milk: A Systematic Review.Perrin MT, Belfort MB, Hagadorn JI, McGrath JM, Taylor SN, Tosi LM, Brownell EA. The Nutritional Composition and Energy Content of Donor Human Milk: A Systematic Review. Advances In Nutrition (Bethesda, Md.) 2020, 11: 960-970. PMID: 32119744, PMCID: PMC7360450, DOI: 10.1093/advances/nmaa014.
- Monitoring of Growth and Body Composition: New Methodologies.Taylor SN, Buck CO. Monitoring of Growth and Body Composition: New Methodologies. World Review Of Nutrition And Dietetics 2021, 122: 32-45. PMID: 34352757, DOI: 10.1159/000514741.
- Calcium, Magnesium, Phosphorus, and Vitamin D.Taylor SN. Calcium, Magnesium, Phosphorus, and Vitamin D. World Review Of Nutrition And Dietetics 2021, 122: 122-139. PMID: 34352758, DOI: 10.1159/000514742.
- Preterm birth among Pacific Islander women and related perinatal outcomes: a scoping review protocol.Wu B, Arslanian KJ, Nyhan K, Taylor S, Shabanova V, Muasau-Howard B, Hawley NL. Preterm birth among Pacific Islander women and related perinatal outcomes: a scoping review protocol. BMJ Open 2021, 11: e050483. PMID: 34728448, PMCID: PMC8565552, DOI: 10.1136/bmjopen-2021-050483.
- Evidence-based Discharge Nutrition to Optimize Preterm Infant Outcomes.Taylor SN, Martin CR. Evidence-based Discharge Nutrition to Optimize Preterm Infant Outcomes. NeoReviews 2022, 23: e108-e116. PMID: 35102382, DOI: 10.1542/neo.23-2-e108.
- Commentary on "compatibility of rapid enteral feeding advances and noninvasive ventilation in preterm infants-an observational study".Buck CO, Taylor SN. Commentary on "compatibility of rapid enteral feeding advances and noninvasive ventilation in preterm infants-an observational study". Pediatric Pulmonology 2022, 57: 1113-1116. PMID: 35191225, DOI: 10.1002/ppul.25867.
- Exclusive Maternal Milk Compared With Exclusive Formula on Growth and Health Outcomes in Very-Low-Birthweight Preterm Infants: Phase II of the Pre-B Project and an Evidence Analysis Center Systematic Review.Taylor SN, Fenton TR, Groh-Wargo S, Gura K, Martin CR, Griffin IJ, Rozga M, Moloney L. Exclusive Maternal Milk Compared With Exclusive Formula on Growth and Health Outcomes in Very-Low-Birthweight Preterm Infants: Phase II of the Pre-B Project and an Evidence Analysis Center Systematic Review. Frontiers In Pediatrics 2021, 9: 793311. PMID: 35280446, PMCID: PMC8913886, DOI: 10.3389/fped.2021.793311.
- Age-related topographic map of magnetic resonance diffusion metrics in neonatal brains.Bobba PS, Weber CF, Mak A, Mozayan A, Malhotra A, Sheth KN, Taylor SN, Vossough A, Grant PE, Scheinost D, Constable RT, Ment LR, Payabvash S. Age-related topographic map of magnetic resonance diffusion metrics in neonatal brains. Human Brain Mapping 2022 PMID: 35599634, DOI: 10.1002/hbm.25956.
- Human Milk Fortification: A Practical Analysis of Current Evidence.Bergner EM, Taylor SN, Gollins LA, Hair AB. Human Milk Fortification: A Practical Analysis of Current Evidence. Clinics In Perinatology 2022, 49: 447-460. PMID: 35659096, DOI: 10.1016/j.clp.2022.02.010.
Clinical Trials
Conditions | Study Title |
---|---|
Pregnancy, Childbirth and the Puerperium | The NICU Antibiotics and Outcomes Trial (NANO) |
Diseases in Infants & Newborns; Infectious Diseases | Evaluation of Pharmacokinetics, Safety, and Tolerability of Ceftazidime-avibactam in Neonates and Infants. (NOOR) |
Diseases of the Endocrine System; Women's Health; Pregnancy, Childbirth and the Puerperium | The effect of lactation on insulin sensitivity and lipolysis in women |