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Sarah Yip, PhD

Associate Professor of Psychiatry

Research & Publications
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Selected Publications

Distinct neural networks predict cocaine versus cannabis treatment outcomesLichenstein S, Kohler R, Ye F, Potenza M, Kiluk B, Yip S. Distinct neural networks predict cocaine versus cannabis treatment outcomes. Molecular Psychiatry 2023, 28: 3365-3372. PMID: 37308679, PMCID: PMC10713861, DOI: 10.1038/s41380-023-02120-0.
Emerging Topics in Computational Psychiatric Research: Clarity Through Complexity?Yip S, Konova A. Emerging Topics in Computational Psychiatric Research: Clarity Through Complexity? Biological Psychiatry 2023, 93: 652-654. PMID: 36948759, DOI: 10.1016/j.biopsych.2023.02.005.
Bayesian network mediation analysis with application to the brain functional connectomeZhao Y, Chen T, Cai J, Lichenstein S, Potenza M, Yip S. Bayesian network mediation analysis with application to the brain functional connectome. Statistics In Medicine 2022, 41: 3991-4005. PMID: 35795965, PMCID: PMC10131252, DOI: 10.1002/sim.9488.
Task-Based Co-Activation Patterns Reliably Predict Resting State Canonical Network Engagement During DevelopmentYe F, Kohler R, Serio B, Lichenstein S, Yip S. Task-Based Co-Activation Patterns Reliably Predict Resting State Canonical Network Engagement During Development. Biological Psychiatry 2022, 91: s83. DOI: 10.1016/j.biopsych.2022.02.225.
From Computation to ClinicYip S, Barch D, Chase H, Flagel S, Huys Q, Konova A, Montague R, Paulus M. From Computation to Clinic. Biological Psychiatry Global Open Science 2022, 3: 319-328. PMID: 37519475, PMCID: PMC10382698, DOI: 10.1016/j.bpsgos.2022.03.011.
Multivariate, Transgenerational Associations of the COVID-19 Pandemic Across Minoritized and Marginalized CommunitiesYip SW, Jordan A, Kohler RJ, Holmes A, Bzdok D. Multivariate, Transgenerational Associations of the COVID-19 Pandemic Across Minoritized and Marginalized Communities. JAMA Psychiatry 2022, 79: 350-358. PMID: 35138333, PMCID: PMC8829750, DOI: 10.1001/jamapsychiatry.2021.4331.
Hyperbolic discounting rates and risk for problematic alcohol use in youth enrolled in the Adolescent Brain and Cognitive Development studyKohler RJ, Lichenstein SD, Yip SW. Hyperbolic discounting rates and risk for problematic alcohol use in youth enrolled in the Adolescent Brain and Cognitive Development study. Addiction Biology 2022, 27: e13160. PMID: 35229959, PMCID: PMC9289942, DOI: 10.1111/adb.13160.
Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 participantsLichenstein SD, Manco N, Cope LM, Egbo L, Garrison KA, Hardee J, Hillmer AT, Reeder K, Stern EF, Worhunsky P, Yip SW. Systematic review of structural and functional neuroimaging studies of cannabis use in adolescence and emerging adulthood: evidence from 90 studies and 9441 participants. Neuropsychopharmacology 2021, 47: 1000-1028. PMID: 34839363, PMCID: PMC8938408, DOI: 10.1038/s41386-021-01226-9.
Densely sampled neuroimaging for maximizing clinical insight in psychiatric and addiction disordersYip SW, Konova AB. Densely sampled neuroimaging for maximizing clinical insight in psychiatric and addiction disorders. Neuropsychopharmacology 2021, 47: 395-396. PMID: 34354248, PMCID: PMC8617277, DOI: 10.1038/s41386-021-01124-0.
Clinical prediction of extra-medical use of prescription pain relievers from a representative United States sampleThompson CL, Alcover KC, Yip SW. Clinical prediction of extra-medical use of prescription pain relievers from a representative United States sample. Preventive Medicine 2021, 149: 106610. PMID: 33989674, DOI: 10.1016/j.ypmed.2021.106610.
Identification and Validation of Distinct Latent Neurodevelopmental Profiles in the Adolescent Brain and Cognitive Development StudyLichenstein SD, Roos C, Kohler R, Kiluk B, Carroll KM, Worhunsky PD, Witkiewitz K, Yip SW. Identification and Validation of Distinct Latent Neurodevelopmental Profiles in the Adolescent Brain and Cognitive Development Study. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2021, 7: 352-361. PMID: 33706021, PMCID: PMC8426420, DOI: 10.1016/j.bpsc.2021.02.013.
Effects of Smoking Status and State on Intrinsic ConnectivityYip SW, Lichenstein SD, Garrison K, Averill CL, Viswanath H, Salas R, Abdallah CG. Effects of Smoking Status and State on Intrinsic Connectivity. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2021, 7: 895-904. PMID: 33618016, PMCID: PMC8373998, DOI: 10.1016/j.bpsc.2021.02.004.
Is monetary reward processing altered in drug-naïve youth with a behavioral addiction? Findings from internet gaming disorderYao YW, Liu L, Worhunsky PD, Lichenstein S, Ma SS, Zhu L, Shi XH, Yang S, Zhang JT, Yip SW. Is monetary reward processing altered in drug-naïve youth with a behavioral addiction? Findings from internet gaming disorder. NeuroImage Clinical 2020, 26: 102202. PMID: 32045732, PMCID: PMC7013339, DOI: 10.1016/j.nicl.2020.102202.
Toward Addiction Prediction: An Overview of Cross-Validated Predictive Modeling Findings and Considerations for Future Neuroimaging ResearchYip SW, Kiluk B, Scheinost D. Toward Addiction Prediction: An Overview of Cross-Validated Predictive Modeling Findings and Considerations for Future Neuroimaging Research. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2019, 5: 748-758. PMID: 31932230, PMCID: PMC8274215, DOI: 10.1016/j.bpsc.2019.11.001.
Dissociable neural substrates of opioid and cocaine use identified via connectome-based modellingLichenstein SD, Scheinost D, Potenza MN, Carroll KM, Yip SW. Dissociable neural substrates of opioid and cocaine use identified via connectome-based modelling. Molecular Psychiatry 2019, 26: 4383-4393. PMID: 31719641, PMCID: PMC7214212, DOI: 10.1038/s41380-019-0586-y.
Clinical validation of reduction in cocaine frequency level as an endpoint in clinical trials for cocaine use disorderRoos CR, Nich C, Mun CJ, Babuscio TA, Mendonca J, Miguel AQC, DeVito EE, Yip SW, Witkiewitz K, Carroll KM, Kiluk BD. Clinical validation of reduction in cocaine frequency level as an endpoint in clinical trials for cocaine use disorder. Drug And Alcohol Dependence 2019, 205: 107648. PMID: 31677490, PMCID: PMC6910212, DOI: 10.1016/j.drugalcdep.2019.107648.
Anhedonia as a Key Clinical Feature in the Maintenance and Treatment of Opioid Use DisorderKiluk BD, Yip SW, DeVito EE, Carroll KM, Sofuoglu M. Anhedonia as a Key Clinical Feature in the Maintenance and Treatment of Opioid Use Disorder. Clinical Psychological Science 2019, 7: 1190-1206. PMID: 32042509, PMCID: PMC7009780, DOI: 10.1177/2167702619855659.
Gambling disorderPotenza MN, Balodis IM, Derevensky J, Grant JE, Petry NM, Verdejo-Garcia A, Yip SW. Gambling disorder. Nature Reviews Disease Primers 2019, 5: 51. PMID: 31346179, DOI: 10.1038/s41572-019-0099-7.
Double‐Blind Placebo‐Controlled Trial of Galantamine for Methadone‐Maintained Individuals With Cocaine Use Disorder: Secondary Analysis of Effects on Illicit Opioid UseCarroll KM, DeVito EE, Yip SW, Nich C, Sofuoglu M. Double‐Blind Placebo‐Controlled Trial of Galantamine for Methadone‐Maintained Individuals With Cocaine Use Disorder: Secondary Analysis of Effects on Illicit Opioid Use. American Journal On Addictions 2019, 28: 238-245. PMID: 31165574, PMCID: PMC9078084, DOI: 10.1111/ajad.12904.
Ten simple rules for predictive modeling of individual differences in neuroimagingScheinost D, Noble S, Horien C, Greene AS, Lake EM, Salehi M, Gao S, Shen X, O’Connor D, Barron DS, Yip SW, Rosenberg MD, Constable RT. Ten simple rules for predictive modeling of individual differences in neuroimaging. NeuroImage 2019, 193: 35-45. PMID: 30831310, PMCID: PMC6521850, DOI: 10.1016/j.neuroimage.2019.02.057.
Connectome-Based Prediction of Cocaine AbstinenceYip SW, Scheinost D, Potenza MN, Carroll KM. Connectome-Based Prediction of Cocaine Abstinence. American Journal Of Psychiatry 2019, 176: 156-164. PMID: 30606049, PMCID: PMC6481181, DOI: 10.1176/appi.ajp.2018.17101147.
Childhood trauma moderates inhibitory control and anterior cingulate cortex activation during stressZhai ZW, Yip SW, Lacadie CM, Sinha R, Mayes LC, Potenza MN. Childhood trauma moderates inhibitory control and anterior cingulate cortex activation during stress. NeuroImage 2018, 185: 111-118. PMID: 30342975, PMCID: PMC6392043, DOI: 10.1016/j.neuroimage.2018.10.049.
Accounting for the uncounted: Physical and affective distress in individuals dropping out of oral naltrexone treatment for opioid use disorderCarroll KM, Nich C, Frankforter TL, Yip SW, Kiluk BD, DeVito EE, Sofuoglu M. Accounting for the uncounted: Physical and affective distress in individuals dropping out of oral naltrexone treatment for opioid use disorder. Drug And Alcohol Dependence 2018, 192: 264-270. PMID: 30300800, PMCID: PMC6203294, DOI: 10.1016/j.drugalcdep.2018.08.019.
Can neuroimaging help combat the opioid epidemic? A systematic review of clinical and pharmacological challenge fMRI studies with recommendations for future researchMoningka H, Lichenstein S, Worhunsky PD, DeVito EE, Scheinost D, Yip SW. Can neuroimaging help combat the opioid epidemic? A systematic review of clinical and pharmacological challenge fMRI studies with recommendations for future research. Neuropsychopharmacology 2018, 44: 259-273. PMID: 30283002, PMCID: PMC6300537, DOI: 10.1038/s41386-018-0232-4.
The Cholinergic System as a Treatment Target for Opioid Use DisorderJensen KP, DeVito EE, Yip S, Carroll KM, Sofuoglu M. The Cholinergic System as a Treatment Target for Opioid Use Disorder. CNS Drugs 2018, 32: 981-996. PMID: 30259415, PMCID: PMC6314885, DOI: 10.1007/s40263-018-0572-y.
Meta-analysis of regional white matter volume in bipolar disorder with replication in an independent sample using coordinates, T-maps, and individual MRI dataPezzoli S, Emsell L, Yip SW, Dima D, Giannakopoulos P, Zarei M, Tognin S, Arnone D, James A, Haller S, Frangou S, Goodwin GM, McDonald C, Kempton MJ. Meta-analysis of regional white matter volume in bipolar disorder with replication in an independent sample using coordinates, T-maps, and individual MRI data. Neuroscience & Biobehavioral Reviews 2017, 84: 162-170. PMID: 29162519, PMCID: PMC5771263, DOI: 10.1016/j.neubiorev.2017.11.005.
Is Neural Processing of Negative Stimuli Altered in Addiction Independent of Drug Effects? Findings From Drug-Naïve Youth with Internet Gaming DisorderYip SW, Gross JJ, Chawla M, Ma SS, Shi XH, Liu L, Yao YW, Zhu L, Worhunsky PD, Zhang J. Is Neural Processing of Negative Stimuli Altered in Addiction Independent of Drug Effects? Findings From Drug-Naïve Youth with Internet Gaming Disorder. Neuropsychopharmacology 2017, 43: 1364-1372. PMID: 29154365, PMCID: PMC5916358, DOI: 10.1038/npp.2017.283.
Altered functional connectivity to stressful stimuli in prenatally cocaine-exposed adolescentsZakiniaeiz Y, Yip SW, Balodis IM, Lacadie CM, Scheinost D, Constable RT, Mayes LC, Sinha R, Potenza MN. Altered functional connectivity to stressful stimuli in prenatally cocaine-exposed adolescents. Drug And Alcohol Dependence 2017, 180: 129-136. PMID: 28888152, PMCID: PMC5808433, DOI: 10.1016/j.drugalcdep.2017.07.030.
Reward-related frontostriatal activity and smoking behavior among adolescents in treatment for smoking cessationGarrison KA, Yip SW, Balodis IM, Carroll KM, Potenza MN, Krishnan-Sarin S. Reward-related frontostriatal activity and smoking behavior among adolescents in treatment for smoking cessation. Drug And Alcohol Dependence 2017, 177: 268-276. PMID: 28651213, PMCID: PMC5564393, DOI: 10.1016/j.drugalcdep.2017.03.035.
Shared Microstructural Features of Behavioral and Substance Addictions Revealed in Areas of Crossing FibersYip SW, Morie KP, Xu J, Constable RT, Malison RT, Carroll KM, Potenza MN. Shared Microstructural Features of Behavioral and Substance Addictions Revealed in Areas of Crossing Fibers. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2017, 2: 188-195. PMID: 28367515, PMCID: PMC5373810, DOI: 10.1016/j.bpsc.2016.03.001.
White-matter crossing-fiber microstructure in adolescents prenatally exposed to cocaineMorie KP, Yip SW, Zhai ZW, Xu J, Hamilton KR, Sinha R, Mayes LC, Potenza MN. White-matter crossing-fiber microstructure in adolescents prenatally exposed to cocaine. Drug And Alcohol Dependence 2017, 174: 23-29. PMID: 28292689, PMCID: PMC5555052, DOI: 10.1016/j.drugalcdep.2017.01.011.
Intra-individual changes in Stroop-related neural activations linked to cigarette abstinence in adolescent smokersYip S, Krishnan-Sarin S, Balodis I, Carroll K, Potenza M. Intra-individual changes in Stroop-related neural activations linked to cigarette abstinence in adolescent smokers. Drug And Alcohol Dependence 2017, 171: e221. DOI: 10.1016/j.drugalcdep.2016.08.603.
Altered intrinsic brain connectivity in prenatally cocaine-exposed adolescentsZakiniaeiz Y, Yip S, Balodis I, Lacadie C, Mayes L, Sinha R, Potenza M. Altered intrinsic brain connectivity in prenatally cocaine-exposed adolescents. Drug And Alcohol Dependence 2017, 171: e222. DOI: 10.1016/j.drugalcdep.2016.08.607.
Alexithymia and addiction: A review and preliminary data suggesting neurobiological links to reward/loss processingMorie K, Yip S, Nich C, Hunkele K, Carroll K, Potenza M. Alexithymia and addiction: A review and preliminary data suggesting neurobiological links to reward/loss processing. Drug And Alcohol Dependence 2017, 171: e149-e150. DOI: 10.1016/j.drugalcdep.2016.08.413.
Gray‐matter relationships to diagnostic and transdiagnostic features of drug and behavioral addictionsYip SW, Worhunsky PD, Xu J, Morie KP, Constable RT, Malison RT, Carroll KM, Potenza MN. Gray‐matter relationships to diagnostic and transdiagnostic features of drug and behavioral addictions. Addiction Biology 2017, 23: 394-402. PMID: 28150390, PMCID: PMC5538947, DOI: 10.1111/adb.12492.
Application of Research Domain Criteria to childhood and adolescent impulsive and addictive disorders: Implications for treatmentYip SW, Potenza MN. Application of Research Domain Criteria to childhood and adolescent impulsive and addictive disorders: Implications for treatment. Clinical Psychology Review 2016, 64: 41-56. PMID: 27876165, PMCID: PMC5423866, DOI: 10.1016/j.cpr.2016.11.003.
Large-scale functional network overlap is a general property of brain functional organization: Reconciling inconsistent fMRI findings from general-linear-model-based analysesXu J, Potenza MN, Calhoun VD, Zhang R, Yip SW, Wall JT, Pearlson GD, Worhunsky PD, Garrison KA, Moran JM. Large-scale functional network overlap is a general property of brain functional organization: Reconciling inconsistent fMRI findings from general-linear-model-based analyses. Neuroscience & Biobehavioral Reviews 2016, 71: 83-100. PMID: 27592153, PMCID: PMC5140707, DOI: 10.1016/j.neubiorev.2016.08.035.
Intra-individual changes in Stroop-related activations linked to cigarette abstinence in adolescent tobacco smokers: Preliminary findingsYip SW, Balodis IM, Carroll KM, Krishnan-Sarin S, Potenza MN. Intra-individual changes in Stroop-related activations linked to cigarette abstinence in adolescent tobacco smokers: Preliminary findings. Drug And Alcohol Dependence 2016, 167: 182-189. PMID: 27567966, PMCID: PMC5082713, DOI: 10.1016/j.drugalcdep.2016.08.019.
Anticipatory reward processing among cocaine-dependent individuals with and without concurrent methadone-maintenance treatment: Relationship to treatment responseYip SW, DeVito EE, Kober H, Worhunsky PD, Carroll KM, Potenza MN. Anticipatory reward processing among cocaine-dependent individuals with and without concurrent methadone-maintenance treatment: Relationship to treatment response. Drug And Alcohol Dependence 2016, 166: 134-142. PMID: 27430401, PMCID: PMC5082418, DOI: 10.1016/j.drugalcdep.2016.07.006.
Prenatal cocaine exposure, illicit-substance use and stress and craving processes during adolescenceYip SW, Lacadie CM, Sinha R, Mayes LC, Potenza MN. Prenatal cocaine exposure, illicit-substance use and stress and craving processes during adolescence. Drug And Alcohol Dependence 2015, 158: 76-85. PMID: 26627911, PMCID: PMC4698087, DOI: 10.1016/j.drugalcdep.2015.11.012.
Different patterns of neural activity among cocaine-dependent individuals with and without current methadone treatment: Relationship to treatment outcomesYip S, Carroll K, Potenza M. Different patterns of neural activity among cocaine-dependent individuals with and without current methadone treatment: Relationship to treatment outcomes. Drug And Alcohol Dependence 2015, 156: e242-e243. DOI: 10.1016/j.drugalcdep.2015.07.653.
Neural function and structure among young men with cannabis dependence: Relationship to treatment responseYip S, DeVito E, Kober H, Carroll K, Potenza M. Neural function and structure among young men with cannabis dependence: Relationship to treatment response. Drug And Alcohol Dependence 2015, 146: e29. DOI: 10.1016/j.drugalcdep.2014.09.759.
Hypoactivation of the Ventral and Dorsal Striatum During Reward and Loss Anticipation in Antipsychotic and Mood Stabilizer-Naive Bipolar DisorderYip SW, Worhunsky PD, Rogers RD, Goodwin GM. Hypoactivation of the Ventral and Dorsal Striatum During Reward and Loss Anticipation in Antipsychotic and Mood Stabilizer-Naive Bipolar Disorder. Neuropsychopharmacology 2014, 40: 658-666. PMID: 25139065, PMCID: PMC4289954, DOI: 10.1038/npp.2014.215.
Prenatal Cocaine Exposure and Adolescent Neural Responses to Appetitive and Stressful StimuliYip SW, Potenza EB, Balodis IM, Lacadie CM, Sinha R, Mayes LC, Potenza MN. Prenatal Cocaine Exposure and Adolescent Neural Responses to Appetitive and Stressful Stimuli. Neuropsychopharmacology 2014, 39: 2824-2834. PMID: 24903650, PMCID: PMC4200493, DOI: 10.1038/npp.2014.133.
Pretreatment measures of brain structure and reward-processing brain function in cannabis dependence: An exploratory study of relationships with abstinence during behavioral treatment 1Yip SW, DeVito EE, Kober H, Worhunsky PD, Carroll KM, Potenza MN. Pretreatment measures of brain structure and reward-processing brain function in cannabis dependence: An exploratory study of relationships with abstinence during behavioral treatment 1. Drug And Alcohol Dependence 2014, 140: 33-41. PMID: 24793365, PMCID: PMC4057888, DOI: 10.1016/j.drugalcdep.2014.03.031.
Cortical glutathione levels in young people with bipolar disorder: a pilot study using magnetic resonance spectroscopyGodlewska BR, Yip SW, Near J, Goodwin GM, Cowen PJ. Cortical glutathione levels in young people with bipolar disorder: a pilot study using magnetic resonance spectroscopy. Psychopharmacology 2013, 231: 327-332. PMID: 23955702, DOI: 10.1007/s00213-013-3244-0.
White matter alterations in antipsychotic- and mood stabilizer-naïve individuals with bipolar II/NOS disorderYip SW, Chandler RA, Rogers RD, Mackay CE, Goodwin GM. White matter alterations in antipsychotic- and mood stabilizer-naïve individuals with bipolar II/NOS disorder. NeuroImage Clinical 2013, 3: 271-278. PMID: 24273712, PMCID: PMC3814955, DOI: 10.1016/j.nicl.2013.08.005.
Reduced Subjective Response to Acute Ethanol Administration Among Young Men with a Broad Bipolar PhenotypeYip SW, Doherty J, Wakeley J, Saunders K, Tzagarakis C, de Wit H, Goodwin GM, Rogers RD. Reduced Subjective Response to Acute Ethanol Administration Among Young Men with a Broad Bipolar Phenotype. Neuropsychopharmacology 2012, 37: 1808-1815. PMID: 22491350, PMCID: PMC3376329, DOI: 10.1038/npp.2012.45.
P.3.018 Reduced subjective response to acute ethanol administration among young men with the bipolar phenotypeYip S, Doherty J, Wakeley J, Saunders K, Tzagarakis C, de Wit H, Goodwin G, Rogers R. P.3.018 Reduced subjective response to acute ethanol administration among young men with the bipolar phenotype. European Neuropsychopharmacology 2012, 22: s67-s68. DOI: 10.1016/s0924-977x(12)70071-8.
Health/Functioning Characteristics, Gambling Behaviors, and Gambling‐Related Motivations in Adolescents Stratified by Gambling Problem Severity: Findings from a High School SurveyYip SW, Desai RA, Steinberg MA, Rugle L, Cavallo DA, Krishnan‐Sarin S, Potenza MN. Health/Functioning Characteristics, Gambling Behaviors, and Gambling‐Related Motivations in Adolescents Stratified by Gambling Problem Severity: Findings from a High School Survey. American Journal On Addictions 2011, 20: 495-508. PMID: 21999494, PMCID: PMC3683237, DOI: 10.1111/j.1521-0391.2011.00180.x.
Reduced genual corpus callosal white matter integrity in pathological gambling and its relationship to alcohol abuse or dependenceYip SW, Lacadie C, Xu J, Worhunsky PD, Fulbright RK, Constable RT, Potenza MN. Reduced genual corpus callosal white matter integrity in pathological gambling and its relationship to alcohol abuse or dependence. The World Journal Of Biological Psychiatry 2011, 14: 129-138. PMID: 21545245, PMCID: PMC3689213, DOI: 10.3109/15622975.2011.568068.
Risk/reward decision-making in schizophrenia: A preliminary examination of the influence of tobacco smoking and relationship to Wisconsin Card Sorting Task performanceYip SW, Sacco KA, George TP, Potenza MN. Risk/reward decision-making in schizophrenia: A preliminary examination of the influence of tobacco smoking and relationship to Wisconsin Card Sorting Task performance. Schizophrenia Research 2009, 110: 156-164. PMID: 19269138, PMCID: PMC2817985, DOI: 10.1016/j.schres.2009.01.012.

Clinical Trials

Conditions	Study Title
Addictive Behaviors	Imaging Synaptic Density in Cocaine and Opiate Addiction In Vivo using 11C-UCB-J PET
Mental Health & Behavioral Research	Connectivity While Coming of Age

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