Samir Gautam, MD/PhD
Assistant Professor of Medicine (Pulmonary, Critical Care and Sleep Medicine)
Research & Publications
Biography
News
Coauthors
Selected Publications
- Sputum alarmins delineate distinct T2 cytokine pathways and unique subtypes of patients with asthmaGautam S, Chu J, Cohen A, Kaur R, Lee S, Wilson G, Liu Q, Gomez J, Rajaveen H, Yan X, Cohn L, Clark B, Chupp G. Sputum alarmins delineate distinct T2 cytokine pathways and unique subtypes of patients with asthma. Allergy 2023, 78: 3274-3277. PMID: 37874609, PMCID: PMC10842366, DOI: 10.1111/all.15915.
- Differences in Mortality Among Patients With Asthma and COPD Hospitalized With COVID-19Liu Y, Rajeevan H, Simonov M, Lee S, Wilson F, Desir G, Vinetz J, Yan X, Wang Z, Clark B, Possick J, Price C, Lutchmansingh D, Ortega H, Zaeh S, Gomez J, Cohn L, Gautam S, Chupp G. Differences in Mortality Among Patients With Asthma and COPD Hospitalized With COVID-19. The Journal Of Allergy And Clinical Immunology In Practice 2023, 11: 3383-3390.e3. PMID: 37454926, PMCID: PMC10787810, DOI: 10.1016/j.jaip.2023.07.006.
- Nonutility of procalcitonin for diagnosing bacterial pneumonia in patients with severe COVID-19Cohen A, Glick L, Lee S, Kunitomo Y, Tsang D, Pitafi S, Toro P, Ristic N, Zhang E, Carey G, Datta R, Dela Cruz C, Gautam S. Nonutility of procalcitonin for diagnosing bacterial pneumonia in patients with severe COVID-19. European Clinical Respiratory Journal 2023, 10: 2174640. PMID: 36815942, PMCID: PMC9930745, DOI: 10.1080/20018525.2023.2174640.
- Severe respiratory viral infection induces procalcitonin in the absence of bacterial pneumoniaGautam S, Cohen AJ, Stahl Y, Toro P, Young GM, Datta R, Yan X, Ristic NT, Bermejo SD, Sharma L, Restrepo M, Dela Cruz CS. Severe respiratory viral infection induces procalcitonin in the absence of bacterial pneumonia. Thorax 2020, 75: 974-981. PMID: 32826284, DOI: 10.1136/thoraxjnl-2020-214896.
- Quantification of bronchoalveolar neutrophil extracellular traps and phagocytosis in murine pneumoniaGautam S, Stahl Y, Young GM, Howell R, Cohen AJ, Tsang DA, Martin T, Sharma L, Dela Cruz CS. Quantification of bronchoalveolar neutrophil extracellular traps and phagocytosis in murine pneumonia. American Journal Of Physiology - Lung Cellular And Molecular Physiology 2020, 319: l661-l669. PMID: 32783617, PMCID: PMC7642899, DOI: 10.1152/ajplung.00316.2020.
- An Activity‐Based Probe for Studying Crosslinking in Live BacteriaGautam S, Kim T, Shoda T, Sen S, Deep D, Luthra R, Ferreira M, Pinho M, Spiegel D. An Activity‐Based Probe for Studying Crosslinking in Live Bacteria. Angewandte Chemie 2015, 127: 10638-10642. DOI: 10.1002/ange.201503869.
- Chemical Probes Reveal an Extraseptal Mode of Cross-Linking in Staphylococcus aureusGautam S, Kim T, Spiegel DA. Chemical Probes Reveal an Extraseptal Mode of Cross-Linking in Staphylococcus aureus. Journal Of The American Chemical Society 2015, 137: 7441-7447. PMID: 26035224, DOI: 10.1021/jacs.5b02972.
- Wall teichoic acids prevent antibody binding to epitopes within the cell wall of Staphylococcus aureusGautam S, Kim T, Lester E, Deep D, Spiegel DA. Wall teichoic acids prevent antibody binding to epitopes within the cell wall of Staphylococcus aureus. ACS Chemical Biology 2015, 11: 25-30. PMID: 26502318, PMCID: PMC5592732, DOI: 10.1021/acschembio.5b00439.
- Impact of Prophylactic Antibacterials on Coagulation Profiles and Bleeding in Patients with Acute Myeloid Leukemia/Myelodysplastic SyndromeAllen C, Gautam S, Cheng W, Pine A, Podoltsev N, Zeidan A, Lee A, Shallis R. Impact of Prophylactic Antibacterials on Coagulation Profiles and Bleeding in Patients with Acute Myeloid Leukemia/Myelodysplastic Syndrome. Acta Haematologica 2023, 146: 287-292. PMID: 37166332, DOI: 10.1159/000530153.
- IFN-γ Is Protective in Cytokine Release Syndrome-associated Extrapulmonary Acute Lung Injury.Sun Y, Hu B, Stanley G, Harris ZM, Gautam S, Homer R, Koff JL, Rajagopalan G. IFN-γ Is Protective in Cytokine Release Syndrome-associated Extrapulmonary Acute Lung Injury. American Journal Of Respiratory Cell And Molecular Biology 2023, 68: 75-89. PMID: 36125351, PMCID: PMC9817908, DOI: 10.1165/rcmb.2022-0117oc.
- Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancerLee S, O’Donovan L, Cohen A, Gautam S, Quagliarello V, Juthani-Mehta M, Datta R. Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancer. Antimicrobial Stewardship & Healthcare Epidemiology 2022, 2: e152. PMID: 36483405, PMCID: PMC9726473, DOI: 10.1017/ash.2022.293.
- Understanding the Host in the Management of Pneumonia. An Official American Thoracic Society Workshop ReportDela Cruz CS, Evans SE, Restrepo MI, Dean N, Torres A, Amara-Elori I, Awasthi S, Caler E, Cao B, Chalmers JD, Chastre J, Cohen TS, Cohen AH, Crothers K, Di YP, Egan ME, Feldman C, Gautam S, Halstead ES, Herold S, Jones BE, Luna C, Niederman MS, Mendez R, Menendez R, Mizgerd JP, Nusrat R, Ramirez J, Shindo Y, Waterer G, Yeligar SM, Wunderink RG. Understanding the Host in the Management of Pneumonia. An Official American Thoracic Society Workshop Report. Annals Of The American Thoracic Society 2021, 18: 1087-1097. PMID: 34242148, PMCID: PMC8328365, DOI: 10.1513/annalsats.202102-209st.
- A 62-Year-Old Woman With Lung Cancer, Ulcerating Rash, and Rapidly Progressive HypoxemiaKunitomo Y, Young G, Datta R, Korn LL, Tanoue L, Gautam S. A 62-Year-Old Woman With Lung Cancer, Ulcerating Rash, and Rapidly Progressive Hypoxemia. CHEST Journal 2020, 158: e191-e196. PMID: 33036118, PMCID: PMC7533682, DOI: 10.1016/j.chest.2020.06.020.
- Fluorescent stem peptide mimics: In situ probes for peptidoglycan crosslinkingGautam S, Kim T, Howell R, Spiegel DA. Fluorescent stem peptide mimics: In situ probes for peptidoglycan crosslinking. 2020, 638: 57-67. PMID: 32416921, DOI: 10.1016/bs.mie.2020.02.016.
- Measurement of Chitinase Activity in Biological SamplesAmick A, Liu Q, Gautam S, Chupp G, Dela Cruz C, Sharma L. Measurement of Chitinase Activity in Biological Samples. Journal Of Visualized Experiments 2019 DOI: 10.3791/60159-v.
- Teaching an Old Intensivist Neutrophil Tricks: Using Alveolar Neutrophilia to Diagnose Ventilator-associated PneumoniaGautam S, Sharma L, Dela Cruz CS. Teaching an Old Intensivist Neutrophil Tricks: Using Alveolar Neutrophilia to Diagnose Ventilator-associated Pneumonia. American Journal Of Respiratory And Critical Care Medicine 2019, 199: 1178-1181. PMID: 30543457, PMCID: PMC6519853, DOI: 10.1164/rccm.201811-2163ed.
- Personalizing the Management of PneumoniaGautam S, Sharma L, Dela Cruz CS. Personalizing the Management of Pneumonia. Clinics In Chest Medicine 2018, 39: 871-900. PMID: 30390755, DOI: 10.1016/j.ccm.2018.08.008.
- A Slick Solution to a Sticky ProblemGautam S, Sharma L, Dela Cruz CS, Spiegel DA. A Slick Solution to a Sticky Problem. Biochemistry 2018, 57: 5923-5924. PMID: 30289246, DOI: 10.1021/acs.biochem.8b00916.
- Pushing the bacterial envelope: Strategies for re-engineering bacterial surfaces with heterologous proteins and sugars.Gautam S, Spiegel DA. Zhao, W. & Karp, J. (Eds.). 2014. Micro- and Nanoengineering of the Cell Surface. Oxford, UK: Elsevier.
- Exterior design: strategies for redecorating the bacterial surface with small moleculesGautam S, Gniadek TJ, Kim T, Spiegel DA. Exterior design: strategies for redecorating the bacterial surface with small molecules. Trends In Biotechnology 2013, 31: 258-267. PMID: 23490213, PMCID: PMC3641905, DOI: 10.1016/j.tibtech.2013.01.012.
- Type 2 inositol 1,4,5‐trisphosphate receptor modulates bile salt export pump activity in rat hepatocytesKruglov EA, Gautam S, Guerra MT, Nathanson MH. Type 2 inositol 1,4,5‐trisphosphate receptor modulates bile salt export pump activity in rat hepatocytes. Hepatology 2011, 54: 1790-1799. PMID: 21748767, PMCID: PMC3205211, DOI: 10.1002/hep.24548.
- ATP8B1 Deficiency Disrupts the Bile Canalicular Membrane Bilayer Structure in Hepatocytes, But FXR Expression and Activity Are MaintainedCai S, Gautam S, Nguyen T, Soroka CJ, Rahner C, Boyer JL. ATP8B1 Deficiency Disrupts the Bile Canalicular Membrane Bilayer Structure in Hepatocytes, But FXR Expression and Activity Are Maintained. Gastroenterology 2008, 136: 1060-1069.e4. PMID: 19027009, PMCID: PMC3439851, DOI: 10.1053/j.gastro.2008.10.025.