Rummana Aslam, MBBS

Current research projects

A. The Automated Test of Embodied Cognition (ATEC) uses motion capture technology and machine learning algorithms to assess cognition in action. Unlike conventional neuropsychological assessments that rely on paper and pencil and computer tasks to measure attention, memory, and executive function, ATEC capturesthose abilities using cognitively demanding physical tasks. Measuring cognition in action is a paradigm shift, in keeping with contemporary neuroscience, and is especially relevant for population with cognitive disordersThe aims are: 1) Algorithm development for scoring, following procedures proven effective in our prototype. Data will include motion capture data that hasalready been collected or is being collected in 2 current VA clinical trials and motion capture data from participants with specific cognitive disorders to be recruited in this proposed study. These include patients with mild to moderate cases of Stroke, Dementia (all cause), mild TBI, Movement Disorders and chronic Alcohol Use Disorder. 2) Improvements in user interface of the computer application along with adaptations for VA Telehealth. This will involve improving the user interface, embedding the scoring algorithms into the interface, redoing some of the video instructions, and developing, and then qualitatively assessing, the Telehealthversion. 3) Develop report templates with scores, interpretation, and treatment recommendations in a version suitable for clinicians and a version for patients and caregivers.The deliverables at the end of 3 years include 1) an easily transferable technology (computer application) that provides an automated high-fidelity administration of ATEC and automated scoring of patient performance.2) Test reports with easily readable graphics and interpretation of findings that are automatically produced. 3) A Telehealth version specific to the VA National TeleNeurology Program (NTNP).

B. Botulinum Toxin-A for Hidradenitis Suppurativa. Randomized double blinded clinical trial

The primary objective of this Phase IV study is to determine if Botulinum Toxin-A induces regression, remission, or relapse of hidradenitis suppurativa lesions.

The secondary objective of this investigation is to determine if Botulinum Toxin-A improves patient-reported quality of life outcomes in hidradenitis suppurativa

C. Digitalization of the Physical Performance Test and Training

The digitalized version of the Physical Performance Test, will be able to measure the movements of the human body with the help of sensors. The two types of sensors used for these measurements are the Inertial Measurement Unit (IMU) and force sensors. Digitizing the conventional test will be used to obtain objective and continuous data from patients undergoing acute stroke rehabilitation and compare to conventional methods. The goal is to increase the accuracy of the assessment of physical performance Computer software will be developed to evaluate the test score of the patient.

D. Effect of Hyperbaric Oxygen Treatment on Recovery from Exercise

The primary objective of this pilot study is to investigate the effect of hyperbaric oxygen treatment on functional recovery from exercise

The secondary objectives of this pilot study are to investigate the effect of hyperbaric oxygen treatment on muscle oxygenation during and after treatment, as well as other physiologic markers of fatigue and recovery.

My research interest focuses on the following areas

1. Wound repair and regeneration - outcomes-based research

2. New innovative applications of hyperbaric oxygen therapy

3. Quantification of physical performance and cognition