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Rohan Khera, MBBS, MS

Assistant Professor

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Research Summary

Dr. Khera’s research focuses on optimal strategies to measure hospital quality of care and patient outcomes across health systems in the United States. His work specifically focuses on unexplained variation in the quality of care and outcomes that may represent a target for interventions to improve healthcare. Dr. Khera has pursued rigorous evaluations of national health policies and their effects on hospital practices and patient outcomes. Another important focus of his group is the financial implication of healthcare services for cardiovascular care. Dr. Khera’s work leverages national registries and large databases, and increasingly focuses on the use of the electronic health record to evaluate both the quality of care patients receive and their outcomes. The work he has led has been published in JAMA, BMJ, Circulation, JAMA Internal Medicine, Journal of the American College of Cardiology, and JAMA Cardiology, among others.

Coauthors

Selected Publications

Adherence to Methodological Standards in Research Using the National Inpatient Sample.Khera R, Angraal S, Couch T, Welsh JW, Nallamothu BK, Girotra S, Chan PS, Krumholz HM. Adherence to Methodological Standards in Research Using the National Inpatient Sample. JAMA 2017, 318:2011-2018.
Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis.Khera R, Murad MH, Chandar AK, Dulai PS, Wang Z, Prokop LJ, Loomba R, Camilleri M, Singh S. Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis. JAMA 2016, 315:2424-34.
Transition to the ICD-10 in the United States: An Emerging Data Chasm.Khera R, Dorsey KB, Krumholz HM. Transition to the ICD-10 in the United States: An Emerging Data Chasm. JAMA 2018, 320:133-134.
Use of Machine Learning Models to Predict Death After Acute Myocardial Infarction.Khera R, Haimovich J, Hurley NC, McNamara R, Spertus JA, Desai N, Rumsfeld JS, Masoudi FA, Huang C, Normand SL, Mortazavi BJ, Krumholz HM. Use of Machine Learning Models to Predict Death After Acute Myocardial Infarction. JAMA Cardiology 2021.
Revascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018.Khera R, Secemsky EA, Wang Y, Desai NR, Krumholz HM, Maddox TM, Shunk KA, Virani SS, Bhatt DL, Curtis J, Yeh RW. Revascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018. JAMA Internal Medicine 2020, 180:1317-1327.
Cost-Related Medication Nonadherence in Adults With Atherosclerotic Cardiovascular Disease in the United States, 2013 to 2017.Khera R, Valero-Elizondo J, Das SR, Virani SS, Kash BA, de Lemos JA, Krumholz HM, Nasir K. Cost-Related Medication Nonadherence in Adults With Atherosclerotic Cardiovascular Disease in the United States, 2013 to 2017. Circulation 2019, 140:2067-2075.
Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac Arrest.Khera R, Chan PS, Donnino M, Girotra S. Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac Arrest. Circulation 2016, 134:2105-2114.
Evaluation of 30-Day Hospital Readmission and Mortality Rates Using Regression-Discontinuity Framework.Khera R, Wang Y, Nasir K, Lin Z, Krumholz HM. Evaluation of 30-Day Hospital Readmission and Mortality Rates Using Regression-Discontinuity Framework. Journal Of The American College Of Cardiology 2019, 74:219-234.
Association of Out-of-Pocket Annual Health Expenditures With Financial Hardship in Low-Income Adults With Atherosclerotic Cardiovascular Disease in the United States.Khera R, Valero-Elizondo J, Okunrintemi V, Saxena A, Das SR, de Lemos JA, Krumholz HM, Nasir K. Association of Out-of-Pocket Annual Health Expenditures With Financial Hardship in Low-Income Adults With Atherosclerotic Cardiovascular Disease in the United States. JAMA Cardiology 2018, 3:729-738.
Post-discharge acute care and outcomes following readmission reduction initiatives: national retrospective cohort study of Medicare beneficiaries in the United States.Khera R, Wang Y, Bernheim SM, Lin Z, Krumholz HM. Post-discharge acute care and outcomes following readmission reduction initiatives: national retrospective cohort study of Medicare beneficiaries in the United States. BMJ (Clinical Research Ed.) 2020, 368:l6831.
Pulselessness After Initiation of Cardiopulmonary Resuscitation for Bradycardia in Hospitalized Children.Khera R, Tang Y, Girotra S, Nadkarni VM, Link MS, Raymond TT, Guerguerian AM, Berg RA, Chan PS. Pulselessness After Initiation of Cardiopulmonary Resuscitation for Bradycardia in Hospitalized Children. Circulation 2019, 140:370-378.
Burden of Catastrophic Health Expenditures for Acute Myocardial Infarction and Stroke Among Uninsured in the United States.Khera R, Hong JC, Saxena A, Arrieta A, Virani SS, Blankstein R, de Lemos JA, Krumholz HM, Nasir K. Burden of Catastrophic Health Expenditures for Acute Myocardial Infarction and Stroke Among Uninsured in the United States. Circulation 2018, 137:408-410.
Hemodynamic Phenotypes of Hypertension Based on Cardiac Output and Systemic Vascular Resistance.Mahajan S, Gu J, Lu Y, Khera R, Spatz ES, Zhang M, Sun N, Zheng X, Zhao H, Lu H, Ma ZJ, Krumholz HM. Hemodynamic Phenotypes of Hypertension Based on Cardiac Output and Systemic Vascular Resistance. The American Journal Of Medicine 2020, 133:e127-e139.
Machine Learning Prediction of Mortality and Hospitalization in Heart Failure With Preserved Ejection Fraction.Angraal S, Mortazavi BJ, Gupta A, Khera R, Ahmad T, Desai NR, Jacoby DL, Masoudi FA, Spertus JA, Krumholz HM. Machine Learning Prediction of Mortality and Hospitalization in Heart Failure With Preserved Ejection Fraction. JACC. Heart Failure 2020, 8:12-21.
Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Replacement-Effective in Stroke Prevention?Khera R, Girotra S. Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Replacement-Effective in Stroke Prevention? JAMA Internal Medicine 2020, 180:785-786.
Burden and Consequences of Financial Hardship From Medical Bills Among Nonelderly Adults With Diabetes Mellitus in the United States.Caraballo C, Valero-Elizondo J, Khera R, Mahajan S, Grandhi GR, Virani SS, Mszar R, Krumholz HM, Nasir K. Burden and Consequences of Financial Hardship From Medical Bills Among Nonelderly Adults With Diabetes Mellitus in the United States. Circulation. Cardiovascular Quality And Outcomes 2020, 13:e006139.
Do or Do Not, There Is No Try: Optimizing Practices to Reduce Readmissions After Acute Myocardial Infarction.Khera R. Do or Do Not, There Is No Try: Optimizing Practices to Reduce Readmissions After Acute Myocardial Infarction. Circulation. Cardiovascular Quality And Outcomes 2020, 13:e006693.
Readmission and Mortality After Hospitalization for Myocardial Infarction and Heart Failure.Ko DT, Khera R, Lau G, Qiu F, Wang Y, Austin PC, Koh M, Lin Z, Lee DS, Wijeysundera HC, Krumholz HM. Readmission and Mortality After Hospitalization for Myocardial Infarction and Heart Failure. Journal Of The American College Of Cardiology 2020, 75:736-746.
Availability of Telemedicine Services Across Hospitals in the United States in 2018: A Cross-sectional Study.Jain S, Khera R, Lin Z, Ross JS, Krumholz HM. Availability of Telemedicine Services Across Hospitals in the United States in 2018: A Cross-sectional Study. Annals Of Internal Medicine 2020, 173:503-505.
Cumulative Burden of Financial Hardship From Medical Bills Across the Spectrum of Diabetes Mellitus and Atherosclerotic Cardiovascular Disease Among Non-Elderly Adults in the United States.Mszar R, Grandhi GR, Valero-Elizondo J, Caraballo C, Khera R, Desai N, Virani SS, Blankstein R, Blaha MJ, Nasir K. Cumulative Burden of Financial Hardship From Medical Bills Across the Spectrum of Diabetes Mellitus and Atherosclerotic Cardiovascular Disease Among Non-Elderly Adults in the United States. Journal Of The American Heart Association 2020, 9:e015523.
An Evaluation of the Vulnerable Physician Workforce in the USA During the Coronavirus Disease-19 Pandemic.Khera R, Dhingra LS, Jain S, Krumholz HM. An Evaluation of the Vulnerable Physician Workforce in the USA During the Coronavirus Disease-19 Pandemic. Journal Of General Internal Medicine 2020, 35:3114-3116.
Rates and Predictors of Patient Underreporting of Hospitalizations During Follow-Up After Acute Myocardial Infarction: An Assessment From the TRIUMPH Study.Caraballo C, Khera R, Jones PG, Decker C, Schulz W, Spertus JA, Krumholz HM. Rates and Predictors of Patient Underreporting of Hospitalizations During Follow-Up After Acute Myocardial Infarction: An Assessment From the TRIUMPH Study. Circulation. Cardiovascular Quality And Outcomes 2020, 13:e006231.
Cost-minimization study of the percutaneous approach to endovascular aortic aneurysm repair.Hong JC, Yang GK, Delarmente BA, Khera R, Price J, Faulds J, Chen JC. Cost-minimization study of the percutaneous approach to endovascular aortic aneurysm repair. Journal Of Vascular Surgery 2020, 71:444-449.
Temporal Trends in Racial Differences in 30-Day Readmission and Mortality Rates After Acute Myocardial Infarction Among Medicare Beneficiaries.Pandey A, Keshvani N, Khera R, Lu D, Vaduganathan M, Joynt Maddox KE, Das SR, Kumbhani DJ, Goyal A, Girotra S, Chan P, Fonarow GC, Matsouaka R, Wang TY, de Lemos JA. Temporal Trends in Racial Differences in 30-Day Readmission and Mortality Rates After Acute Myocardial Infarction Among Medicare Beneficiaries. JAMA Cardiology 2020, 5:136-145.
Prevalence and Effects of Food Insecurity and Social Support on Financial Toxicity in and Healthcare Use by Patients With Inflammatory Bowel Diseases.Nguyen NH, Khera R, Ohno-Machado L, Sandborn WJ, Singh S. Prevalence and Effects of Food Insecurity and Social Support on Financial Toxicity in and Healthcare Use by Patients With Inflammatory Bowel Diseases. Clinical Gastroenterology And Hepatology : The Official Clinical Practice Journal Of The American Gastroenterological Association 2020.
Education level and outcomes after acute myocardial infarction in China.Huo X, Khera R, Zhang L, Herrin J, Bai X, Wang Q, Lu Y, Nasir K, Hu S, Li J, Li X, Zheng X, Masoudi FA, Spertus JA, Krumholz HM, Jiang L. Education level and outcomes after acute myocardial infarction in China. Heart (British Cardiac Society) 2019, 105:946-952.
Financial Hardship From Medical Bills Among Nonelderly U.S. Adults With Atherosclerotic Cardiovascular Disease.Valero-Elizondo J, Khera R, Saxena A, Grandhi GR, Virani SS, Butler J, Samad Z, Desai NR, Krumholz HM, Nasir K. Financial Hardship From Medical Bills Among Nonelderly U.S. Adults With Atherosclerotic Cardiovascular Disease. Journal Of The American College Of Cardiology 2019, 73:727-732.
Association of Income Disparities with Patient-Reported Healthcare Experience.Okunrintemi V, Khera R, Spatz ES, Salami JA, Valero-Elizondo J, Warraich HJ, Virani SS, Blankstein R, Blaha MJ, Pawlik TM, Dharmarajan K, Krumholz HM, Nasir K. Association of Income Disparities with Patient-Reported Healthcare Experience. Journal Of General Internal Medicine 2019, 34:884-892.
Association Between Hospital Recognition for Resuscitation Guideline Adherence and Rates of Survival for In-Hospital Cardiac Arrest.Khera R, Tang Y, Link MS, Krumholz HM, Girotra S, Chan PS. Association Between Hospital Recognition for Resuscitation Guideline Adherence and Rates of Survival for In-Hospital Cardiac Arrest. Circulation. Cardiovascular Quality And Outcomes 2019, 12:e005429.
Publicly Reported Readmission Measures and the Hospital Readmissions Reduction Program: A False Equivalence?Khera R, Horwitz LI, Lin Z, Krumholz HM. Publicly Reported Readmission Measures and the Hospital Readmissions Reduction Program: A False Equivalence? Annals Of Internal Medicine 2018, 168:670-671.
Association of access to exercise opportunities and cardiovascular mortality.Angraal S, Gupta A, Khera R, Nasir K, Desai NR. Association of access to exercise opportunities and cardiovascular mortality. American Heart Journal 2019, 212:152-156.
Financial Toxicity of Acute Cardiovascular Disease in India: A Dive Beyond the Tip of an Iceberg.Nasir K, Khera R. Financial Toxicity of Acute Cardiovascular Disease in India: A Dive Beyond the Tip of an Iceberg. JAMA Network Open 2019, 2:e193839.
National Trends in Healthcare-Associated Infections for Five Common Cardiovascular Conditions.Miller PE, Guha A, Khera R, Chouairi F, Ahmad T, Nasir K, Addison D, Desai NR. National Trends in Healthcare-Associated Infections for Five Common Cardiovascular Conditions. The American Journal Of Cardiology 2019, 124:1140-1148.
Variation and Disparities in Awareness of Myocardial Infarction Symptoms Among Adults in the United States.Mahajan S, Valero-Elizondo J, Khera R, Desai NR, Blankstein R, Blaha MJ, Virani SS, Kash BA, Zoghbi WA, Krumholz HM, Nasir K. Variation and Disparities in Awareness of Myocardial Infarction Symptoms Among Adults in the United States. JAMA Network Open 2019, 2:e1917885.
Intraosseous versus intravenous access in patients with out-of-hospital cardiac arrest: Insights from the resuscitation outcomes consortium continuous chest compression trial.Mody P, Brown SP, Kudenchuk PJ, Chan PS, Khera R, Ayers C, Pandey A, Kern K, de Lemos JA, Link MS, Idris AH. Intraosseous versus intravenous access in patients with out-of-hospital cardiac arrest: Insights from the resuscitation outcomes consortium continuous chest compression trial. Resuscitation 2019, 134:69-75.
Managing Implantable Cardioverter-Defibrillators at End-of-Life: Practical Challenges and Care Considerations.Khera R, Pandey A, Link MS, Sulistio MS. Managing Implantable Cardioverter-Defibrillators at End-of-Life: Practical Challenges and Care Considerations. The American Journal Of The Medical Sciences 2019, 357:143-150.
Targeted temperature management for cardiac arrest.Mody P, Kulkarni N, Khera R, Link MS. Targeted temperature management for cardiac arrest. Progress In Cardiovascular Diseases 2019, 62:272-278.
Diagnostic and prognostic utility of cardiac troponin in post-cardiac arrest care.Agusala V, Khera R, Cheeran D, Mody P, Reddy PP, Link MS. Diagnostic and prognostic utility of cardiac troponin in post-cardiac arrest care. Resuscitation 2019, 141:69-72.
Effect of Neutropenic Diet on Infection Rates in Cancer Patients With Neutropenia: A Meta-analysis of Randomized Controlled Trials.Ball S, Brown TJ, Das A, Khera R, Khanna S, Gupta A. Effect of Neutropenic Diet on Infection Rates in Cancer Patients With Neutropenia: A Meta-analysis of Randomized Controlled Trials. American Journal Of Clinical Oncology 2019, 42:270-274.
Administrative Billing Codes for Identifying Patients With Cardiac Arrest.DeZorzi C, Boyle B, Qazi A, Luthra K, Khera R, Chan PS, Girotra S. Administrative Billing Codes for Identifying Patients With Cardiac Arrest. Journal Of The American College Of Cardiology 2019, 73:1598-1600.
Persistent socioeconomic disparities in cardiovascular risk factors and health in the United States: Medical Expenditure Panel Survey 2002-2013.Valero-Elizondo J, Hong JC, Spatz ES, Salami JA, Desai NR, Rana JS, Khera R, Virani SS, Blankstein R, Blaha MJ, Nasir K. Persistent socioeconomic disparities in cardiovascular risk factors and health in the United States: Medical Expenditure Panel Survey 2002-2013. Atherosclerosis 2018, 269:301-305.
Impact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional study.Khera R, Lu Y, Lu J, Saxena A, Nasir K, Jiang L, Krumholz HM. Impact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional study. BMJ (Clinical Research Ed.) 2018, 362:k2357.
Rising Mortality in Patients With Heart Failure in the United States: Facts Versus Fiction.Khera R, Dharmarajan K, Krumholz HM. Rising Mortality in Patients With Heart Failure in the United States: Facts Versus Fiction. JACC. Heart Failure 2018, 6:610-612.
Sex and Race Differences in the Utilization and Outcomes of Coronary Artery Bypass Grafting Among Medicare Beneficiaries, 1999-2014.Angraal S, Khera R, Wang Y, Lu Y, Jean R, Dreyer RP, Geirsson A, Desai NR, Krumholz HM. Sex and Race Differences in the Utilization and Outcomes of Coronary Artery Bypass Grafting Among Medicare Beneficiaries, 1999-2014. Journal Of The American Heart Association 2018, 7.
Trends in 30-Day Readmission Rates for Medicare and Non-Medicare Patients in the Era of the Affordable Care Act.Angraal S, Khera R, Zhou S, Wang Y, Lin Z, Dharmarajan K, Desai NR, Bernheim SM, Drye EE, Nasir K, Horwitz LI, Krumholz HM. Trends in 30-Day Readmission Rates for Medicare and Non-Medicare Patients in the Era of the Affordable Care Act. The American Journal Of Medicine 2018, 131:1324-1331.e14.
Association Between Financial Burden, Quality of Life, and Mental Health Among Those With Atherosclerotic Cardiovascular Disease in the United States.Annapureddy A, Valero-Elizondo J, Khera R, Grandhi GR, Spatz ES, Dreyer RP, Desai NR, Krumholz HM, Nasir K. Association Between Financial Burden, Quality of Life, and Mental Health Among Those With Atherosclerotic Cardiovascular Disease in the United States. Circulation. Cardiovascular Quality And Outcomes 2018, 11:e005180.
Role of Hospital Volumes in Identifying Low-Performing and High-Performing Aortic and Mitral Valve Surgical Centers in the United States.Khera R, Pandey A, Koshy T, Ayers C, Nallamothu BK, Das SR, Drazner MH, Jessen ME, Kirtane AJ, Gardner TJ, de Lemos JA, Bhatt DL, Kumbhani DJ. Role of Hospital Volumes in Identifying Low-Performing and High-Performing Aortic and Mitral Valve Surgical Centers in the United States. JAMA Cardiology 2017, 2:1322-1331.
Association of the Hospital Readmissions Reduction Program With Mortality During and After Hospitalization for Acute Myocardial Infarction, Heart Failure, and Pneumonia.Khera R, Dharmarajan K, Wang Y, Lin Z, Bernheim SM, Wang Y, Normand ST, Krumholz HM. Association of the Hospital Readmissions Reduction Program With Mortality During and After Hospitalization for Acute Myocardial Infarction, Heart Failure, and Pneumonia. JAMA Network Open 2018, 1:e182777.
Effects of the Hospital Readmissions Reduction Program.Khera R, Krumholz HM. Effects of the Hospital Readmissions Reduction Program. Circulation. Cardiovascular Quality And Outcomes 2018, 11:e005083.
Trends in Use and Expenditures of Brand-name Atorvastatin After Introduction of Generic Atorvastatin.Warraich HJ, Salami JA, Khera R, Valero-Elizondo J, Okunrintemi V, Nasir K. Trends in Use and Expenditures of Brand-name Atorvastatin After Introduction of Generic Atorvastatin. JAMA Internal Medicine 2018, 178:719-721.
Trends in Diabetes-Related Preventable Hospitalizations in the U.S., 2005-2014.Rubens M, Saxena A, Ramamoorthy V, Khera R, Hong J, Veledar E, Nasir K. Trends in Diabetes-Related Preventable Hospitalizations in the U.S., 2005-2014. Diabetes Care 2018, 41:e72-e73.
Increasing Sepsis Rates in the United States: Results From National Inpatient Sample, 2005 to 2014.Rubens M, Saxena A, Ramamoorthy V, Das S, Khera R, Hong J, Armaignac D, Veledar E, Nasir K, Gidel L. Increasing Sepsis Rates in the United States: Results From National Inpatient Sample, 2005 to 2014. Journal Of Intensive Care Medicine 2020, 35:858-868.
Usefulness of a Simple Algorithm to Identify Hypertensive Patients Who Benefit from Intensive Blood Pressure Lowering.Wang S, Khera R, Das SR, Vigen R, Wang T, Luo X, Lu R, Zhan X, Xiao G, Vongpatanasin W, Xie Y. Usefulness of a Simple Algorithm to Identify Hypertensive Patients Who Benefit from Intensive Blood Pressure Lowering. The American Journal Of Cardiology 2018, 122:248-254.
Hospital Variation in the Utilization and Implementation of Targeted Temperature Management in Out-of-Hospital Cardiac Arrest.Khera R, Humbert A, Leroux B, Nichol G, Kudenchuk P, Scales D, Baker A, Austin M, Newgard CD, Radecki R, Vilke GM, Sawyer KN, Sopko G, Idris AH, Wang H, Chan PS, Kurz MC. Hospital Variation in the Utilization and Implementation of Targeted Temperature Management in Out-of-Hospital Cardiac Arrest. Circulation. Cardiovascular Quality And Outcomes 2018, 11:e004829.
The heart failure readmission quagmire: taking a deep dive to find solutions.Khera R, Pandey A. The heart failure readmission quagmire: taking a deep dive to find solutions. European Journal Of Heart Failure 2018, 20:315-316.
Comparison of Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Chronic Kidney Disease.Kumar N, Khera R, Garg N, Echouffo-Tcheugui JB, Venkatraman A, Pandey A, Bhatt DL. Comparison of Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Chronic Kidney Disease. The American Journal Of Cardiology 2018, 121:343-348.
Effects of Weight-Loss Medications on Cardiometabolic Risk Profiles: A Systematic Review and Network Meta-analysis.Khera R, Pandey A, Chandar AK, Murad MH, Prokop LJ, Neeland IJ, Berry JD, Camilleri M, Singh S. Effects of Weight-Loss Medications on Cardiometabolic Risk Profiles: A Systematic Review and Network Meta-analysis. Gastroenterology 2018, 154:1309-1319.e7.
Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction: A Study-Level Pooled Analysis.Pandey A, Khera R, Park B, Haykowsky M, Borlaug BA, Lewis GD, Kitzman DW, Butler J, Berry JD. Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction: A Study-Level Pooled Analysis. JACC. Heart Failure 2018, 6:117-126.
Annual Burden and Costs of Hospitalization for High-Need, High-Cost Patients With Chronic Gastrointestinal and Liver Diseases.Nguyen NH, Khera R, Ohno-Machado L, Sandborn WJ, Singh S. Annual Burden and Costs of Hospitalization for High-Need, High-Cost Patients With Chronic Gastrointestinal and Liver Diseases. Clinical Gastroenterology And Hepatology : The Official Clinical Practice Journal Of The American Gastroenterological Association 2018, 16:1284-1292.e30.
Comparison of Outcomes of Transfemoral Versus Transapical Approach for Transcatheter Aortic Valve Implantation.Kumar N, Khera R, Fonarow GC, Bhatt DL. Comparison of Outcomes of Transfemoral Versus Transapical Approach for Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122:1520-1526.
Readmissions of adults within three age groups following hospitalization for pneumonia: Analysis from the Nationwide Readmissions Database.Jain S, Khera R, Mortensen EM, Weissler JC. Readmissions of adults within three age groups following hospitalization for pneumonia: Analysis from the Nationwide Readmissions Database. PloS One 2018, 13:e0203375.
Early coronary angiography and survival after out-of-hospital cardiac arrest: a systematic review and meta-analysis.Khera R, CarlLee S, Blevins A, Schweizer M, Girotra S. Early coronary angiography and survival after out-of-hospital cardiac arrest: a systematic review and meta-analysis. Open Heart 2018, 5:e000809.
With Great Power Comes Great Responsibility: Big Data Research From the National Inpatient Sample.Khera R, Krumholz HM. With Great Power Comes Great Responsibility: Big Data Research From the National Inpatient Sample. Circulation. Cardiovascular Quality And Outcomes 2017, 10.
Updated Cost-effectiveness Assessments of PCSK9 Inhibitors From the Perspectives of the Health System and Private Payers: Insights Derived From the FOURIER Trial.Arrieta A, Hong JC, Khera R, Virani SS, Krumholz HM, Nasir K. Updated Cost-effectiveness Assessments of PCSK9 Inhibitors From the Perspectives of the Health System and Private Payers: Insights Derived From the FOURIER Trial. JAMA Cardiology 2017, 2:1369-1374.
Comparative Effectiveness of Pharmacologic Interventions for Pulmonary Arterial Hypertension: A Systematic Review and Network Meta-Analysis.Jain S, Khera R, Girotra S, Badesch D, Wang Z, Murad MH, Blevins A, Schmidt GA, Singh S, Gerke AK. Comparative Effectiveness of Pharmacologic Interventions for Pulmonary Arterial Hypertension: A Systematic Review and Network Meta-Analysis. Chest 2017, 151:90-105.
Administrative Codes for Capturing In-Hospital Cardiac Arrest.Khera R, Spertus JA, Starks MA, Tang Y, Bradley SM, Girotra S, Chan PS. Administrative Codes for Capturing In-Hospital Cardiac Arrest. JAMA Cardiology 2017, 2:1275-1277.
Contemporary Epidemiology of Heart Failure in Fee-For-Service Medicare Beneficiaries Across Healthcare Settings.Khera R, Pandey A, Ayers CR, Agusala V, Pruitt SL, Halm EA, Drazner MH, Das SR, de Lemos JA, Berry JD. Contemporary Epidemiology of Heart Failure in Fee-For-Service Medicare Beneficiaries Across Healthcare Settings. Circulation. Heart Failure 2017, 10.
Response to "the Use of Mechanical Support Devices in Percutaneous Coronary Interventions: the Controversy?"Khera R, Girotra S. Response to "the Use of Mechanical Support Devices in Percutaneous Coronary Interventions: the Controversy?" The American Journal Of Cardiology 2017, 120:e5.
Editorial Commentary: Deconstructing the dogma: Its time to untangle and reassess acute myocardial infarction care.Khera R, Kumbhani DJ. Editorial Commentary: Deconstructing the dogma: Its time to untangle and reassess acute myocardial infarction care. Trends In Cardiovascular Medicine 2017, 27:492-493.
Comparison of Readmission Rates After Acute Myocardial Infarction in 3 Patient Age Groups (18 to 44, 45 to 64, and ≥65 Years) in the United States.Khera R, Jain S, Pandey A, Agusala V, Kumbhani DJ, Das SR, Berry JD, de Lemos JA, Girotra S. Comparison of Readmission Rates After Acute Myocardial Infarction in 3 Patient Age Groups (18 to 44, 45 to 64, and ≥65 Years) in the United States. The American Journal Of Cardiology 2017, 120:1761-1767.
Predictors of Death in Adults With Duchenne Muscular Dystrophy-Associated Cardiomyopathy.Cheeran D, Khan S, Khera R, Bhatt A, Garg S, Grodin JL, Morlend R, Araj FG, Amin AA, Thibodeau JT, Das S, Drazner MH, Mammen PPA. Predictors of Death in Adults With Duchenne Muscular Dystrophy-Associated Cardiomyopathy. Journal Of The American Heart Association 2017, 6.
Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis.Dulai PS, Singh S, Marquez E, Khera R, Prokop LJ, Limburg PJ, Gupta S, Murad MH. Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis. BMJ (Clinical Research Ed.) 2016, 355:i6188.
Herpes zoster ophthalmicus complicated by encephalitis.Jain S, Khera R. Herpes zoster ophthalmicus complicated by encephalitis. CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne 2016, 188:E74.
Use of Mechanical Circulatory Support in Percutaneous Coronary Intervention in the United States.Khera R, Cram P, Vaughan-Sarrazin M, Horwitz PA, Girotra S. Use of Mechanical Circulatory Support in Percutaneous Coronary Intervention in the United States. The American Journal Of Cardiology 2016, 117:10-6.
Use of Pulmonary Artery Catheterization in US Patients With Heart Failure, 2001-2012.Pandey A, Khera R, Kumar N, Golwala H, Girotra S, Fonarow GC. Use of Pulmonary Artery Catheterization in US Patients With Heart Failure, 2001-2012. JAMA Internal Medicine 2016, 176:129-32.
Reply.Singh S, Khera R, Murad MH, Loomba R. Reply. Hepatology (Baltimore, Md.) 2016, 64:694.
Trends in hospitalization for takotsubo cardiomyopathy in the United States.Khera R, Light-McGroary K, Zahr F, Horwitz PA, Girotra S. Trends in hospitalization for takotsubo cardiomyopathy in the United States. American Heart Journal 2016, 172:53-63.
Weekend hospitalizations for acute aortic dissection have a higher risk of in-hospital mortality compared to weekday hospitalizations.Kumar N, Venkatraman A, Pandey A, Khera R, Garg N. Weekend hospitalizations for acute aortic dissection have a higher risk of in-hospital mortality compared to weekday hospitalizations. International Journal Of Cardiology 2016, 214:448-50.
Mechanical Circulatory Support and Rationale for Future Research-Reply.Khera R, Girotra S. Mechanical Circulatory Support and Rationale for Future Research-Reply. JAMA Internal Medicine 2016, 176:714-5.
Racial Differences in Outcomes after Acute Ischemic Stroke Hospitalization in the United States.Kumar N, Khera R, Pandey A, Garg N. Racial Differences in Outcomes after Acute Ischemic Stroke Hospitalization in the United States. Journal Of Stroke And Cerebrovascular Diseases : The Official Journal Of National Stroke Association 2016, 25:1970-7.
Response to "Higher mortality among males in takotsubo cardiomyopathy".Khera R, Girotra S. Response to "Higher mortality among males in takotsubo cardiomyopathy". American Heart Journal 2016, 176:e3.
Atrial fibrillation associated hospitalizations in patients with end-stage renal disease in the United States, 2003-2012.Kumar N, Khera R, Garg N. Atrial fibrillation associated hospitalizations in patients with end-stage renal disease in the United States, 2003-2012. Heart Rhythm : The Official Journal Of The Heart Rhythm Society 2016, 13:2027-33.
Variation in Hospital Use and Outcomes Associated With Pulmonary Artery Catheterization in Heart Failure in the United States.Khera R, Pandey A, Kumar N, Singh R, Bano S, Golwala H, Kumbhani DJ, Girotra S, Fonarow GC. Variation in Hospital Use and Outcomes Associated With Pulmonary Artery Catheterization in Heart Failure in the United States. Circulation. Heart Failure 2016, 9.
Trends in the use of percutaneous ventricular assist devices: analysis of national inpatient sample data, 2007 through 2012.Khera R, Cram P, Lu X, Vyas A, Gerke A, Rosenthal GE, Horwitz PA, Girotra S. Trends in the use of percutaneous ventricular assist devices: analysis of national inpatient sample data, 2007 through 2012. JAMA Internal Medicine 2015, 175:941-50.
Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary Embolism.Jain S, Khera R, Suneja M, Gehlbach B, Kuperman E. Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary Embolism. The American Journal Of The Medical Sciences 2015, 350:501-7.
Racial disparities in outcomes after cardiac surgery: the role of hospital quality.Khera R, Vaughan-Sarrazin M, Rosenthal GE, Girotra S. Racial disparities in outcomes after cardiac surgery: the role of hospital quality. Current Cardiology Reports 2015, 17:29.
Distinct interneuronal networks influence excitability of the surround during movement initiation.Thirugnanasambandam N, Khera R, Wang H, Kukke SN, Hallett M. Distinct interneuronal networks influence excitability of the surround during movement initiation. Journal Of Neurophysiology 2015, 114:1102-8.
Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta-analysis.Singh S, Khera R, Allen AM, Murad MH, Loomba R. Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta-analysis. Hepatology (Baltimore, Md.) 2015, 62:1417-32.
Letter by Khera et al Regarding Article, "Impact of Annual Operator and Institutional Volume on Percutaneous Coronary Intervention Outcomes: A 5-Year United States Experience (2005-2009)".Khera R, Cram P, Girotra S. Letter by Khera et al Regarding Article, "Impact of Annual Operator and Institutional Volume on Percutaneous Coronary Intervention Outcomes: A 5-Year United States Experience (2005-2009)". Circulation 2015, 132:e35.
Pacemaker Dependency after Cardiac Surgery: A Systematic Review of Current Evidence.Steyers CM, Khera R, Bhave P. Pacemaker Dependency after Cardiac Surgery: A Systematic Review of Current Evidence. PloS One 2015, 10:e0140340.
Gender bias in child care and child health: global patterns.Khera R, Jain S, Lodha R, Ramakrishnan S. Gender bias in child care and child health: global patterns. Archives Of Disease In Childhood. Fetal And Neonatal Edition 2014, 99:369-74.
"Inflammation and arterial stiffness in humans".Jain S, Khera R, Corrales-Medina VF, Townsend RR, Chirinos JA. "Inflammation and arterial stiffness in humans". Atherosclerosis 2014, 237:381-90.
Membrane-bound complement regulatory proteins as biomarkers and potential therapeutic targets for SLE.Das N, Biswas B, Khera R. Membrane-bound complement regulatory proteins as biomarkers and potential therapeutic targets for SLE. Advances In Experimental Medicine And Biology 2013, 735:55-81.
Gender differences in the utilisation of surgery for congenital heart disease in India.Ramakrishnan S, Khera R, Jain S, Saxena A, Kailash S, Karthikeyan G, Kothari SS, Juneja R, Bhargava B, Kalaivani M, Mehta M, Bahl VK, Airan B. Gender differences in the utilisation of surgery for congenital heart disease in India. Heart (British Cardiac Society) 2011, 97:1920-5.
Diffuse large B-cell lymphoma: experience from a tertiary care center in North India.Khera R, Jain S, Kumar L, Thulkar S, Vijayraghwan M, Dawar R. Diffuse large B-cell lymphoma: experience from a tertiary care center in North India. Medical Oncology (Northwood, London, England) 2010, 27:310-8.
Complement Receptor 1: disease associations and therapeutic implications.Khera R, Das N. Complement Receptor 1: disease associations and therapeutic implications. Molecular Immunology 2009, 46:761-72.
Characteristics of cardiac catheterization laboratory directors at the 2017 U.S. News & World Report top 100 U.S. cardiovascular hospitals.Murugiah K, Annapureddy AR, Khera R, Lansky A, Curtis JP. Characteristics of cardiac catheterization laboratory directors at the 2017 U.S. News & World Report top 100 U.S. cardiovascular hospitals. Catheterization And Cardiovascular Interventions : Official Journal Of The Society For Cardiac Angiography & Interventions 2021, 97:E624-E626.
Financial Hardship After Traumatic Injury: Risk Factors and Drivers of Out-of-Pocket Health Expenses.O'Neill KM, Jean RA, Gross CP, Becher RD, Khera R, Elizondo JV, Nasir K. Financial Hardship After Traumatic Injury: Risk Factors and Drivers of Out-of-Pocket Health Expenses. The Journal Of Surgical Research 2020, 256:1-12.
Digital Phenotyping of Myocardial Dysfunction With 12-Lead ECG: Tiptoeing Into the Future With Machine Learning.Nasir K, Khera R. Digital Phenotyping of Myocardial Dysfunction With 12-Lead ECG: Tiptoeing Into the Future With Machine Learning. Journal Of The American College Of Cardiology 2020, 76:942-944.
Association of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers with the Risk of Hospitalization and Death in Hypertensive Patients with Coronavirus Disease-19.Khera R, Clark C, Lu Y, Guo Y, Ren S, Truax B, Spatz ES, Murugiah K, Lin Z, Omer SB, Vojta D, Krumholz HM. Association of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers with the Risk of Hospitalization and Death in Hypertensive Patients with Coronavirus Disease-19. MedRxiv : The Preprint Server For Health Sciences 2020.
Evaluation of the Anticipated Burden of COVID-19 on Hospital-Based Healthcare Services Across the United States.Khera R, Jain S, Lin Z, Ross JS, Krumholz H. Evaluation of the Anticipated Burden of COVID-19 on Hospital-Based Healthcare Services Across the United States. MedRxiv : The Preprint Server For Health Sciences 2020.
An Evaluation of the Vulnerable Physician Workforce in the United States During the Coronavirus Disease-19 Pandemic.Khera R, Dhingra LS, Jain S, Krumholz H. An Evaluation of the Vulnerable Physician Workforce in the United States During the Coronavirus Disease-19 Pandemic. MedRxiv : The Preprint Server For Health Sciences 2020.
Financial Toxicity in Atherosclerotic Cardiovascular Disease in the United States: Current State and Future Directions.Khera R, Valero-Elizondo J, Nasir K. Financial Toxicity in Atherosclerotic Cardiovascular Disease in the United States: Current State and Future Directions. Journal Of The American Heart Association 2020, 9:e017793.
The Upcoming Epidemic of Heart Failure in South Asia.Martinez-Amezcua P, Haque W, Khera R, Kanaya AM, Sattar N, Lam CSP, Harikrishnan S, Shah SJ, Kandula NR, Jose PO, Narayan KMV, Agyemang C, Misra A, Jenum AK, Bilal U, Nasir K, Cainzos-Achirica M. The Upcoming Epidemic of Heart Failure in South Asia. Circulation. Heart Failure 2020, 13:e007218.
Trends in Reoperative Coronary Artery Bypass Graft Surgery for Older Adults in the United States, 1998 to 2017.Mori M, Wang Y, Murugiah K, Khera R, Gupta A, Vallabhajosyula P, Masoudi FA, Geirsson A, Krumholz HM. Trends in Reoperative Coronary Artery Bypass Graft Surgery for Older Adults in the United States, 1998 to 2017. Journal Of The American Heart Association 2020, 9:e016980.
National Estimates of Financial Hardship From Medical Bills and Cost-related Medication Nonadherence in Patients With Inflammatory Bowel Diseases in the United States.Nguyen NH, Khera R, Dulai PS, Boland BS, Ohno-Machado L, Sandborn WJ, Singh S. National Estimates of Financial Hardship From Medical Bills and Cost-related Medication Nonadherence in Patients With Inflammatory Bowel Diseases in the United States. Inflammatory Bowel Diseases 2020.
Temporal Trends in Heart Failure Incidence Among Medicare Beneficiaries Across Risk Factor Strata, 2011 to 2016.Khera R, Kondamudi N, Zhong L, Vaduganathan M, Parker J, Das SR, Grodin JL, Halm EA, Berry JD, Pandey A. Temporal Trends in Heart Failure Incidence Among Medicare Beneficiaries Across Risk Factor Strata, 2011 to 2016. JAMA Network Open 2020, 3:e2022190.
Association Between Sociodemographic Determinants and Disparities in Stroke Symptom Awareness Among US Young Adults.Mszar R, Mahajan S, Valero-Elizondo J, Yahya T, Sharma R, Grandhi GR, Khera R, Virani SS, Lichtman J, Khan SU, Cainzos-Achirica M, Vahidy FS, Krumholz HM, Nasir K. Association Between Sociodemographic Determinants and Disparities in Stroke Symptom Awareness Among US Young Adults. Stroke; A Journal Of Cerebral Circulation 2020, 51:3552-3561.
Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Body Mass Index.Khera R, Pandey A, Ayers CR, Carnethon MR, Greenland P, Ndumele CE, Nambi V, Seliger SL, Chaves PHM, Safford MM, Cushman M, Xanthakis V, Ramachandran VS, Mentz RJ, Correa A, Lloyd-Jones DM, Berry JD, de Lemos JA, Neeland IJ. Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Body Mass Index. JAMA Network Open 2020, 3:e2023242.
The Promise of Big Data and Digital Solutions in Building a Cardiovascular Learning System: Opportunities and Barriers.Mori M, Khera R, Lin Z, Ross JS, Schulz W, Krumholz HM. The Promise of Big Data and Digital Solutions in Building a Cardiovascular Learning System: Opportunities and Barriers. Methodist DeBakey Cardiovascular Journal 2020, 16:212-219.
Temporal Changes and Institutional Variation in Use of Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction With Multivessel Coronary Artery Disease in the United States: An NCDR Research to Practice Project.Secemsky EA, Butala N, Raja A, Khera R, Wang Y, Curtis JP, Maddox TM, Virani SS, Armstrong EJ, Shunk KA, Brindis RG, Bhatt D, Yeh RW. Temporal Changes and Institutional Variation in Use of Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction With Multivessel Coronary Artery Disease in the United States: An NCDR Research to Practice Project. JAMA Cardiology 2021, 6:574-580.
Pumping the Breaks on Health Care Costs of Cardiac Surgery by Focusing on Postacute Care Spending.Mori M, Khera R. Pumping the Breaks on Health Care Costs of Cardiac Surgery by Focusing on Postacute Care Spending. Circulation. Cardiovascular Quality And Outcomes 2020, 13:e007253.
Association of Body Mass Index and Age With Morbidity and Mortality in Patients Hospitalized With COVID-19: Results From the American Heart Association COVID-19 Cardiovascular Disease Registry.Hendren NS, de Lemos JA, Ayers C, Das SR, Rao A, Carter S, Rosenblatt A, Walchok JG, Omar W, Khera R, Hegde AA, Drazner MH, Neeland IJ, Grodin JL. Association of Body Mass Index and Age With Morbidity and Mortality in Patients Hospitalized With COVID-19: Results From the American Heart Association COVID-19 Cardiovascular Disease Registry. Circulation 2021, 143:135-144.
Evaluation of Internet-Based Crowdsourced Fundraising to Cover Health Care Costs in the United States.Angraal S, Zachariah AG, Raaisa R, Khera R, Rao P, Krumholz HM, Spertus JA. Evaluation of Internet-Based Crowdsourced Fundraising to Cover Health Care Costs in the United States. JAMA Network Open 2021, 4:e2033157.
Association of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers with the Risk of Hospitalization and Death in Hypertensive Patients with Coronavirus Disease-19.Khera R, Clark C, Lu Y, Guo Y, Ren S, Truax B, Spatz ES, Murugiah K, Lin Z, Omer SB, Vojta D, Krumholz HM. Association of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers with the Risk of Hospitalization and Death in Hypertensive Patients with Coronavirus Disease-19. Journal Of The American Heart Association 2021, e018086.
Prevalence of Missing Data in the National Cancer Database and Association With Overall Survival.Yang DX, Khera R, Miccio JA, Jairam V, Chang E, Yu JB, Park HS, Krumholz HM, Aneja S. Prevalence of Missing Data in the National Cancer Database and Association With Overall Survival. JAMA Network Open 2021, 4:e211793.
Financial Hardship from Medical Bills Among Adults with Chronic Liver Diseases: National Estimates from the United States.Lago-Hernandez C, Nguyen NH, Khera R, Loomba R, Asrani SK, Singh S. Financial Hardship from Medical Bills Among Adults with Chronic Liver Diseases: National Estimates from the United States. Hepatology (Baltimore, Md.) 2021.
Electronic health record risk score provides earlier prognostication of clinical outcomes in patients admitted to the cardiac intensive care unit.Kunitomo Y, Thomas A, Chouairi F, Canavan ME, Kochar A, Khera R, Katz JN, Murphy C, Jentzer J, Ahmad T, Desai NR, Brennan J, Miller PE. Electronic health record risk score provides earlier prognostication of clinical outcomes in patients admitted to the cardiac intensive care unit. American Heart Journal 2021, 238:85-88.
A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST).Oikonomou EK, Van Dijk D, Parise H, Suchard MA, de Lemos J, Antoniades C, Velazquez EJ, Miller EJ, Khera R. A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST). European Heart Journal 2021.
Performance of the Pooled Cohort Equations in Hispanic Individuals Across the United States: Insights From the Multi-Ethnic Study of Atherosclerosis and the Dallas Heart Study.Flores Rosario K, Mehta A, Ayers C, Engel Gonzalez P, Pandey A, Khera R, Kaplan R, Blaha MJ, Khera A, Blumenthal RS, Nasir K, Rodriguez CJ, Joshi PH. Performance of the Pooled Cohort Equations in Hispanic Individuals Across the United States: Insights From the Multi-Ethnic Study of Atherosclerosis and the Dallas Heart Study. Journal Of The American Heart Association 2021, 10:e018410.
Financial burden, distress, and toxicity in cardiovascular disease.Slavin SD, Khera R, Zafar SY, Nasir K, Warraich HJ. Financial burden, distress, and toxicity in cardiovascular disease. American Heart Journal 2021, 238:75-84.
Contemporary National Patterns of Eligibility and Utilization of Novel Cardioprotective Anti-hyperglycemic agents in Type 2 Diabetes.Nargesi AA, Jeyashanmugaraja GP, Desai N, Lipska K, Krumholz H, Khera R. Contemporary National Patterns of Eligibility and Utilization of Novel Cardioprotective Anti-hyperglycemic agents in Type 2 Diabetes. Journal Of The American Heart Association 2021, e021084.
Out-of-pocket Annual Health Expenditures and Financial Toxicity from Healthcare Costs in Patients with Heart Failure in the United States.Wang SY, Valero-Elizondo J, Ali HJ, Pandey A, Cainzos-Achirica M, Krumholz HM, Nasir K, Khera R. Out-of-pocket Annual Health Expenditures and Financial Toxicity from Healthcare Costs in Patients with Heart Failure in the United States. Journal Of The American Heart Association 2021, e022164.
Projected 30- day out-of-pocket costs and total spending on pancreatic enzyme replacement therapy under Medicare Part D.Gupta A, Premnath N, Sedhom R, Beg MS, Khera R, Laheru DA, Dusetzina SB. Projected 30- day out-of-pocket costs and total spending on pancreatic enzyme replacement therapy under Medicare Part D. Pancreatology : Official Journal Of The International Association Of Pancreatology (IAP) ... [et Al.] 2021.
Accuracy of Computable Phenotyping Approaches for SARS-CoV-2 Infection and COVID-19 Hospitalizations from the Electronic Health Record.Khera R, Mortazavi BJ, Sangha V, Warner F, Young HP, Ross JS, Shah ND, Theel ES, Jenkinson WG, Knepper C, Wang K, Peaper D, Martinello RA, Brandt CA, Lin Z, Ko AI, Krumholz HM, Pollock BD, Schulz WL. Accuracy of Computable Phenotyping Approaches for SARS-CoV-2 Infection and COVID-19 Hospitalizations from the Electronic Health Record. MedRxiv : The Preprint Server For Health Sciences 2021.

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