Rachel Lampert, MD, FACC
Research & Publications
Biography
News
Research Summary
Although psychologic stress and sudden cardiac death have been strongly correlated in epidemiological studies, the underlying physiologic link remains poorly understood. The ICD population allows evaluation of effects of mental stress on arrhythmia. Recent investigation has included evaluation of effects of mental stress on ventricular tachycardia as well as mechanisms and prognostic implications of this effect. Ongoing studies include emotional triggering of atrial fibrillation and the role of stress reactivity.
A second, related area of interest involves heart rate variability, a measurement of autonomic balance derived from ambulatory ECG monitoring. Heart rate variability can provide a measure of effects of acute or chronic stress. Previous investigations include a study of correlations of socioeconomic status and life stress with heart rate variability, and an ongoing study of the predictive value of heart rate variability changes with stress.
Clinical aspects of ICD therapy, including safety of sports for patients with ICDs represent another avenue of research.
Specialized Terms: Arrhythmias, stress, and the autonomic nervous system; Management issues for patients with implantable defibrillators; End of life; Sports; Sports and exercise cardiology
Coauthors
Research Interests
Arrhythmias, Cardiac; Autonomic Nervous System; Cardiology; Sports Medicine; Stress, Physiological; Exercise; Defibrillators, Implantable
Selected Publications
- Safety of sports for athletes with implantable cardioverter-defibrillators: results of a prospective, multinational registry.Lampert R, Olshansky B, Heidbuchel H, Lawless C, Saarel E, Ackerman M, Calkins H, Estes NA, Link MS, Maron BJ, Marcus F, Scheinman M, Wilkoff BL, Zipes DP, Berul CI, Cheng A, Law I, Loomis M, Barth C, Brandt C, Dziura J, Li F, Cannom D. Safety of sports for athletes with implantable cardioverter-defibrillators: results of a prospective, multinational registry. Circulation 2013, 127:2021-30.
- Impact of a recent lead recall on utilization of implantable cardioverter defibrillators: data from the NCDR ICD Registry™.Bhatt P, Curtis J, Wang Y, Lampert R. Impact of a recent lead recall on utilization of implantable cardioverter defibrillators: data from the NCDR ICD Registry™. Journal Of Cardiovascular Electrophysiology 2012, 23:861-5.
- Patients' attitudes and perceptions of implantable cardioverter-defibrillators: potential barriers to appropriate primary prophylaxis.Yuhas J, Mattocks K, Gravelin L, Remetz M, Foley J, Fazio R, Lampert R. Patients' attitudes and perceptions of implantable cardioverter-defibrillators: potential barriers to appropriate primary prophylaxis. Pacing And Clinical Electrophysiology : PACE 2012, 35:1179-87.
- Patient preferences for deactivation of implantable cardioverter-defibrillators.Dodson JA, Fried TR, Van Ness PH, Goldstein NE, Lampert R. Patient preferences for deactivation of implantable cardioverter-defibrillators. JAMA Internal Medicine 2013, 173:377-9.
- Safety of pacemaker implantation in nonagenarians: an analysis of the healthcare cost and utilization project-nationwide inpatient sample.Mandawat A, Curtis JP, Mandawat A, Njike VY, Lampert R. Safety of pacemaker implantation in nonagenarians: an analysis of the healthcare cost and utilization project-nationwide inpatient sample. Circulation 2013, 127:1453-65, 1465e1-2.
- Anger-induced T-wave alternans predicts future ventricular arrhythmias in patients with implantable cardioverter-defibrillators.Lampert R, Shusterman V, Burg M, McPherson C, Batsford W, Goldberg A, Soufer R. Anger-induced T-wave alternans predicts future ventricular arrhythmias in patients with implantable cardioverter-defibrillators. Journal Of The American College Of Cardiology 2009, 53:774-8.
- Implantable cardioverter-defibrillator shocks increase T-wave alternans.Lampert R, Soufer R, McPherson CA, Batsford WP, Tirado S, Earley C, Goldberg A, Shusterman V. Implantable cardioverter-defibrillator shocks increase T-wave alternans. Journal Of Cardiovascular Electrophysiology 2007, 18:512-7.
- Electrophysiologic characteristics of anger-triggered arrhythmias.Stopper M, Joska T, Burg MM, Batsford WP, McPherson CA, Jain D, Lampert R. Electrophysiologic characteristics of anger-triggered arrhythmias. Heart Rhythm : The Official Journal Of The Heart Rhythm Society 2007, 4:268-73.
- Cost advantage of dual-chamber versus single-chamber cardioverter-defibrillator implantation.Goldberger Z, Elbel B, McPherson CA, Paltiel AD, Lampert R. Cost advantage of dual-chamber versus single-chamber cardioverter-defibrillator implantation. Journal Of The American College Of Cardiology 2005, 46:850-7.
- Depression as a predictor for appropriate shocks among patients with implantable cardioverter-defibrillators: results from the Triggers of Ventricular Arrhythmias (TOVA) study.Whang W, Albert CM, Sears SF, Lampert R, Conti JB, Wang PJ, Singh JP, Ruskin JN, Muller JE, Mittleman MA. Depression as a predictor for appropriate shocks among patients with implantable cardioverter-defibrillators: results from the Triggers of Ventricular Arrhythmias (TOVA) study. Journal Of The American College Of Cardiology 2005, 45:1090-5.
Clinical Trials
| Conditions | Study Title |
|---|---|
| Mental Health & Behavioral Research; Tobacco Addiction | Imaging Tobacco Smoking Withdrawal using [11C]PHNO |
| Diseases of the Cardiovascular System | Product Surveillance Registry (PSR) |