Po-Han Chen, MD, PhD
Instructor in Pathology
Research & Publications
Biography
News
Research Summary
Hematopathology and molecular pathology including novel biomarkers. Cellular engineering for immunotherapy.
Coauthors
Selected Publications
- “Double‐hit” ineffective erythropoiesis—concurrent β‐thalassemia with α‐gene triplication and myelodysplastic syndrome with SF3B1 mutationChen P, Gorshein E, Tormey C, Siddon A, Perincheri S. “Double‐hit” ineffective erythropoiesis—concurrent β‐thalassemia with α‐gene triplication and myelodysplastic syndrome with SF3B1 mutation. American Journal Of Hematology 2023, 98: 984-988. PMID: 36688500, DOI: 10.1002/ajh.26856.
- Recognizing the microgranular variant of acute promyelocytic leukemia when considering leukapheresisGisriel S, Chen P, Tormey C, Siddon A. Recognizing the microgranular variant of acute promyelocytic leukemia when considering leukapheresis. Transfusion 2022, 63: 277-278. PMID: 36426743, DOI: 10.1111/trf.17195.
- A case of acute myeloid leukemia with unusual germline CEBPA mutation: lessons learned about mutation detection, location, and penetranceMendoza H, Chen PH, Pine AB, Siddon AJ, Bale AE, Gowda L, Killie A, Richards J, Varin-Tremblay C, Kloss R, Podoltsev NA. A case of acute myeloid leukemia with unusual germline CEBPA mutation: lessons learned about mutation detection, location, and penetrance. Leukemia & Lymphoma 2020, 62: 1251-1254. PMID: 33345654, DOI: 10.1080/10428194.2020.1861276.
- Expression of lymphoid enhancer-binding factor 1 in breast fibroepithelial lesionsChen PH, Bossuyt V, Reisenbichler E. Expression of lymphoid enhancer-binding factor 1 in breast fibroepithelial lesions. Human Pathology 2020, 108: 68-75. PMID: 33245988, DOI: 10.1016/j.humpath.2020.11.009.
- Bilateral Signet-ring Stromal Tumor of the Ovary: A Case Report With Next-generation Sequencing Analysis and FOXL2 Mutation TestingChen PH, Hui P, Buza N. Bilateral Signet-ring Stromal Tumor of the Ovary: A Case Report With Next-generation Sequencing Analysis and FOXL2 Mutation Testing. International Journal Of Gynecological Pathology 2020, 39: 193-198. PMID: 30676431, DOI: 10.1097/pgp.0000000000000579.
- Clinicopathologic characteristics and novel biomarkers of aggressive B-cell lymphomas in the nasopharynxChen PH, Yang Y, O'Malley DP, Xu ML. Clinicopathologic characteristics and novel biomarkers of aggressive B-cell lymphomas in the nasopharynx. Annals Of Diagnostic Pathology 2019, 41: 129-135. PMID: 31247533, DOI: 10.1016/j.anndiagpath.2019.06.007.
- Disseminated Toxoplasmosis Post Bone Marrow TransplantChen PH, Fyfe-Kirschner B. Disseminated Toxoplasmosis Post Bone Marrow Transplant. Autopsy Pathology Program. Northfield, IL: College of American Pathologists, in press.
- Expression and Purification of Class 7 Semaphorin and Its PlexinC1 Receptor Using Baculovirus-Mediated Mammalian Cell Gene Transduction.Chen X, Chen PH, He X. Expression and Purification of Class 7 Semaphorin and Its PlexinC1 Receptor Using Baculovirus-Mediated Mammalian Cell Gene Transduction. Methods In Molecular Biology (Clifton, N.J.) 2017, 1493: 41-56. PMID: 27787841, PMCID: PMC5706453, DOI: 10.1007/978-1-4939-6448-2_3.
- Structure of Full-Length Human PDGFRβ Bound to Its Activating Ligand PDGF-B as Determined by Negative-Stain Electron Microscopy.Chen PH, Unger V, He X. Structure of Full-Length Human PDGFRβ Bound to Its Activating Ligand PDGF-B as Determined by Negative-Stain Electron Microscopy. Journal Of Molecular Biology 2015, 427: 3921-34. PMID: 26463591, PMCID: PMC4663128, DOI: 10.1016/j.jmb.2015.10.003.
- Platelet-derived growth factors and their receptors: structural and functional perspectives.Chen PH, Chen X, He X. Platelet-derived growth factors and their receptors: structural and functional perspectives. Biochimica Et Biophysica Acta 2013, 1834: 2176-86. PMID: 23137658, PMCID: PMC3612563, DOI: 10.1016/j.bbapap.2012.10.015.
- The structural basis of R-spondin recognition by LGR5 and RNF43.Chen PH, Chen X, Lin Z, Fang D, He X. The structural basis of R-spondin recognition by LGR5 and RNF43. Genes & Development 2013, 27: 1345-50. PMID: 23756651, PMCID: PMC3701190, DOI: 10.1101/gad.219915.113.
- Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor.Jiang X, Liu H, Chen X, Chen PH, Fischer D, Sriraman V, Yu HN, Arkinstall S, He X. Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 12491-6. PMID: 22802634, PMCID: PMC3411987, DOI: 10.1073/pnas.1206643109.