Pain and Pleasure are mediated by overlapping neurochemical pathways; however, little is known about how the brain mediates the perception of pain and pleasure using very similar brain circuitry and neurochemicals. The interaction of pain and pleasure in the brain is reflected in co-morbid conditions such as chronic pain and obesity. Hence, pathological pain and overeating (due to disruption in perception of food pleasure) are good clinical examples of how we can tackle this question. We use functional magnetic resonance imaging (fMRI) as well as psychophysical (pain and food pleasure perception) and neuro-hormonal measures to address these questions.
Specialized Terms: Chronic pain, Obesity
Neural Mechanisms of Obesity in Chronic Low Back Pain
Behavior and Behavior Mechanisms; Obesity; Chronic Pain; Psychiatry and Psychology