Nicola Santoro, MD, PhD
Associate Professor Adjunct
Research & Publications
Biography
News
Research Summary
Genetics of obesity, type 2 diabetes, hepatic steatosis, dyslipidemia in obese youths
Coauthors
Research Interests
Metabolic Diseases; Nutrition Disorders
Public Health Interests
Genetics, Genomics, Epigenetics; Metabolism; Nutrition; Obesity; Child/Adolescent Health
Selected Publications
- Effect of Gut Microbiota and PNPLA3 rs738409 Variant on Nonalcoholic Fatty Liver Disease (NAFLD) in Obese Youth.Monga Kravetz A, Testerman T, Galuppo B, Graf J, Pierpont B, Siebel S, Feinn R, Santoro N. Effect of Gut Microbiota and PNPLA3 rs738409 Variant on Nonalcoholic Fatty Liver Disease (NAFLD) in Obese Youth. The Journal Of Clinical Endocrinology And Metabolism 2020, 105 PMID: 32561908, PMCID: PMC7458486, DOI: 10.1210/clinem/dgaa382.
- Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota?Trico D, Di Sessa A, Caprio S, Chalasani N, Liu W, Liang T, Graf J, Herzog R, Johnson CD, Umano GR, Feldstein AE, Santoro N. Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota? Antioxidants & Redox Signaling 2019, 30: 241-250. PMID: 28279074, PMCID: PMC6277079, DOI: 10.1089/ars.2017.7049.
- The rs626283 Variant in the MBOAT7 Gene is Associated with Insulin Resistance and Fatty Liver in Caucasian Obese Youth.Umano GR, Caprio S, Di Sessa A, Chalasani N, Dykas DJ, Pierpont B, Bale AE, Santoro N. The rs626283 Variant in the MBOAT7 Gene is Associated with Insulin Resistance and Fatty Liver in Caucasian Obese Youth. The American Journal Of Gastroenterology 2018, 113: 376-383. PMID: 29485130, DOI: 10.1038/ajg.2018.1.
- Metabolic Features of Nonalcoholic Fatty Liver (NAFL) in Obese Adolescents: Findings From a Multiethnic Cohort.Tricò D, Caprio S, Rosaria Umano G, Pierpont B, Nouws J, Galderisi A, Kim G, Mata MM, Santoro N. Metabolic Features of Nonalcoholic Fatty Liver (NAFL) in Obese Adolescents: Findings From a Multiethnic Cohort. Hepatology (Baltimore, Md.) 2018, 68: 1376-1390. PMID: 29665034, PMCID: PMC6173637, DOI: 10.1002/hep.30035.
- Role of TM6SF2 rs58542926 in the pathogenesis of nonalcoholic pediatric fatty liver disease: A multiethnic study.Goffredo M, Caprio S, Feldstein AE, D'Adamo E, Shaw MM, Pierpont B, Savoye M, Zhao H, Bale AE, Santoro N. Role of TM6SF2 rs58542926 in the pathogenesis of nonalcoholic pediatric fatty liver disease: A multiethnic study. Hepatology (Baltimore, Md.) 2016, 63: 117-25. PMID: 26457389, PMCID: PMC4688225, DOI: 10.1002/hep.28283.
Clinical Trials
Conditions | Study Title |
---|---|
Diseases of the Digestive System - Liver; Obesity & Weight Control | Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) |
Children's Health; Diabetes Mellitus - Type 2; Diseases of the Endocrine System | Pathogenesis of Youth and Type 2 Diabetes and Prediabetes |
Children's Health; Diseases of the Endocrine System; Immune System | Study to investigate adipocyte cell and lipid turnover in obese adolescents |
Children's Health; Diabetes Mellitus - Type 2; Diseases of the Cardiovascular System; Diseases of the Endocrine System; Genetics - Pediatric; Obesity & Weight Control | Prevalence of Carbohydrate Intolerance in Lean and Obese Children |