Minghao Zhong, MD, PhD
Associate Professor Adjunct in Pathology
Research & Publications
Biography
News
Locations
Coauthors
Selected Publications
- A novel key driver gene of Alzheimer’s disease impacts AD‐related cognitive deficit, pathology and neuro‐inflammation in sex‐ and APOE‐specific mannersCai D, Guo L, Cao J, Zhang L, Huang M, Hou J, Zhu L, Julia T, Zhong M, Goate A, Zhang B. A novel key driver gene of Alzheimer’s disease impacts AD‐related cognitive deficit, pathology and neuro‐inflammation in sex‐ and APOE‐specific manners. Alzheimer's & Dementia 2022, 17 DOI: 10.1002/alz.054111.
- A novel interaction between AD risk genes synaptojanin 1 and reticulon‐3 potentially impacts synaptic function and endo‐lysosomal trafficking during disease development and progressionCai D, Huang M, Cao J, Hou J, Zhu L, Zhang L, Pero A, Guo L, Julia T, Zhong M, Goate A, Zhang B, Yan R. A novel interaction between AD risk genes synaptojanin 1 and reticulon‐3 potentially impacts synaptic function and endo‐lysosomal trafficking during disease development and progression. Alzheimer's & Dementia 2020, 16 DOI: 10.1002/alz.043247.
- A Comparative Analysis of Immunohistochemical Profile of Primary and Metastatic Endometrial Endometrioid CarcinomaXu K, Ye Q, Han L, Zhong M. A Comparative Analysis of Immunohistochemical Profile of Primary and Metastatic Endometrial Endometrioid Carcinoma. American Journal Of Clinical Pathology 2020, 154: s32-s33. DOI: 10.1093/ajcp/aqaa161.066.
- Detecting FLI1 Fusion by Immunohistochemistry (IHC) Stain in Prostatic AdenocarcinomaXu K, Budhai A, Pattarkine R, Zhong M. Detecting FLI1 Fusion by Immunohistochemistry (IHC) Stain in Prostatic Adenocarcinoma. American Journal Of Clinical Pathology 2019, 152: s72-s73. DOI: 10.1093/ajcp/aqz113.087.
- Orbital Lesions: A Retrospective Review From a Single InstituteSalib C, Adem P, Juechter K, Bortz J, Zhong M. Orbital Lesions: A Retrospective Review From a Single Institute. American Journal Of Clinical Pathology 2018, 150: s10-s10. DOI: 10.1093/ajcp/aqy090.023.
- Utility of Pax2 and Bcl-2 Immunohistochemical Stains in Detecting Early Endometrioid Endometrial CarcinomaYe Q, Yoon E, Han L, Zhong M. Utility of Pax2 and Bcl-2 Immunohistochemical Stains in Detecting Early Endometrioid Endometrial Carcinoma. American Journal Of Clinical Pathology 2018, 150: s116-s117. DOI: 10.1093/ajcp/aqy098.280.
- A Giant Fibroepithelial Polyp of the Small Bowel Associated with High-Grade ObstructionLee H, Sade I, Gilani S, Zhong M, Lombardo G. A Giant Fibroepithelial Polyp of the Small Bowel Associated with High-Grade Obstruction. The American Surgeon 2018, 84: 210-211. PMID: 30401014, DOI: 10.1177/000313481808400701.
- From Bedside to Endoscopy to Microscopy to Diagnosis: Samples Collection and ProcessingYoon E, Zhong M. From Bedside to Endoscopy to Microscopy to Diagnosis: Samples Collection and Processing. 2018, 97-105. DOI: 10.1007/978-3-319-51263-1_9.
- Pathology of Urothelial Malignancies of the Upper Urinary TractHajiyeva S, Zhong M. Pathology of Urothelial Malignancies of the Upper Urinary Tract. 2018, 107-117. DOI: 10.1007/978-3-319-51263-1_10.
- 334 Whole Exome Sequencing of End Stage Renal Disease Associated Papillary Renal Cell Carcinoma (PRCCs)Farooq T, Saeed F, Zhang D, Huang W, Yin C, Zhong M. 334 Whole Exome Sequencing of End Stage Renal Disease Associated Papillary Renal Cell Carcinoma (PRCCs). American Journal Of Clinical Pathology 2018, 149: s144-s144. DOI: 10.1093/ajcp/aqx127.333.
- 344 Detection of ERG Rearrangement in Formalin-Fixed Paraffin-Embedded Tissue of Prostatic Adenocarcinoma by Targeted RNA-seqSaeed F, Zhuge J, Huang W, Yang X, Volyanskyy K, Dimitrova N, Fallon J, Zhong M. 344 Detection of ERG Rearrangement in Formalin-Fixed Paraffin-Embedded Tissue of Prostatic Adenocarcinoma by Targeted RNA-seq. American Journal Of Clinical Pathology 2018, 149: s148-s148. DOI: 10.1093/ajcp/aqx127.343.
- Abstract 4549: Identification of clinically relevant patterns in complex genomic interactions of glioblastoma multiformeDimitrova N, Volyanskyy K, Menkovski V, Cheung Y, Zhong M, Fallon J, Vail E. Abstract 4549: Identification of clinically relevant patterns in complex genomic interactions of glioblastoma multiforme. Cancer Research 2017, 77: 4549-4549. DOI: 10.1158/1538-7445.am2017-4549.
- [P4–043]: DEVELOPING NOVEL THERAPIES FOR ALZHEIMER'S DISEASE TARGETING BRAIN PHOSPHOLIPID DYSREGULATIONCai D, Gaamouch F, Zhu L, Ohlmeyer M, Zhong M, Zhong M, Zhang B. [P4–043]: DEVELOPING NOVEL THERAPIES FOR ALZHEIMER'S DISEASE TARGETING BRAIN PHOSPHOLIPID DYSREGULATION. Alzheimer's & Dementia 2017, 13: p1272-p1273. DOI: 10.1016/j.jalz.2017.06.1907.
- Identification of distinctive patterns in cell signaling pathways in glioblastoma multiforme subtypes using gene expression TCGA data sets.Volyanskyy K, Zhong M, Keswarpu P, Fallon J, Fanucchi M, Dimitrova N. Identification of distinctive patterns in cell signaling pathways in glioblastoma multiforme subtypes using gene expression TCGA data sets. Journal Of Clinical Oncology 2017, 35: e23162-e23162. DOI: 10.1200/jco.2017.35.15_suppl.e23162.
- Benign and Malignant Brenner Tumors Show an Absence of TERT Promoter Mutations That Are Commonly Present in Urothelial CarcinomaKhani F, Diolombi M, Khattar P, Huang W, Fallon J, Epstein J, Zhong M. Benign and Malignant Brenner Tumors Show an Absence of TERT Promoter Mutations That Are Commonly Present in Urothelial Carcinoma. The American Journal Of Surgical Pathology 2016, 40: 1291-1295. PMID: 27299795, DOI: 10.1097/pas.0000000000000680.
- Sclerosing Pneumocytoma, A Mimicker of Lung Adenocarcinoma: Case ReportSaeed F, Zhong M. Sclerosing Pneumocytoma, A Mimicker of Lung Adenocarcinoma: Case Report. American Journal Of Clinical Pathology 2016, 146: 251. DOI: 10.1093/ajcp/aqw159.022.
- Loss of Fructose-1,6-bisphosphatase 1 Expression in Kidney NeoplasmYoon E, Hajiyeva S, Barasch S, Volyanskyy K, Mao Y, Dimitrova N, Ronny F, Fallon J, Zhong M. Loss of Fructose-1,6-bisphosphatase 1 Expression in Kidney Neoplasm. American Journal Of Clinical Pathology 2016, 146: 319. DOI: 10.1093/ajcp/aqw159.090.
- Carbonic Anhydrase (CAIX) Expression as Diagnostic Aid in Epithelial Ovarian Cancers and Its Clinical ImplicationFarooq T, Pua T, Han L, Zhong M. Carbonic Anhydrase (CAIX) Expression as Diagnostic Aid in Epithelial Ovarian Cancers and Its Clinical Implication. American Journal Of Clinical Pathology 2016, 146: 2. DOI: 10.1093/ajcp/aqw161.002.
- Abstract 3651: Normal versus tumor and subtype prediction in renal cell carcinoma TCGA data setsVolyanskyy K, Mao Y, Cheung Y, Santhanam B, Menkovski V, Aleksovski Z, Zhong M, Fallon J, Dimitrova N. Abstract 3651: Normal versus tumor and subtype prediction in renal cell carcinoma TCGA data sets. Cancer Research 2016, 76: 3651-3651. DOI: 10.1158/1538-7445.am2016-3651.
- TFE3-Fusion Variant Analysis Defines Specific Clinicopathologic Associations Among Xp11 Translocation CancersArgani P, Zhong M, Reuter V, Fallon J, Epstein J, Netto G, Antonescu C. TFE3-Fusion Variant Analysis Defines Specific Clinicopathologic Associations Among Xp11 Translocation Cancers. The American Journal Of Surgical Pathology 2016, 40: 723-737. PMID: 26975036, PMCID: PMC4864095, DOI: 10.1097/pas.0000000000000631.
- Frequency of Adrenal Gland Lesions in Tertiary Hospital Over 14 YearsYoon E, Khattar P, Sann L, Zhong M. Frequency of Adrenal Gland Lesions in Tertiary Hospital Over 14 Years. American Journal Of Clinical Pathology 2015, 144: a372-a372. DOI: 10.1093/ajcp/144.suppl2.372.
- Reliability of PAX8 IHC Stain in Pelvic and Peritoneal LesionsYoon E, Vail E, Sann L, Zhong M. Reliability of PAX8 IHC Stain in Pelvic and Peritoneal Lesions. American Journal Of Clinical Pathology 2015, 144: a371-a371. DOI: 10.1093/ajcp/144.suppl2.371.
- Reduction of Synaptojanin 1 Accelerates Aβ Clearance and Attenuates Cognitive Deterioration in an Alzheimer Mouse Model*Zhu L, Zhong M, Zhao J, Rhee H, Caesar I, Knight E, Volpicelli-Daley L, Bustos V, Netzer W, Liu L, Lucast L, Ehrlich M, Robakis N, Gandy S, Cai D. Reduction of Synaptojanin 1 Accelerates Aβ Clearance and Attenuates Cognitive Deterioration in an Alzheimer Mouse Model*. Journal Of Biological Chemistry 2013, 288: 32050-32063. PMID: 24052255, PMCID: PMC3814799, DOI: 10.1074/jbc.m113.504365.
- B-Raf and the inhibitors: from bench to bedsideHuang T, Karsy M, Zhuge J, Zhong M, Liu D. B-Raf and the inhibitors: from bench to bedside. Journal Of Hematology & Oncology 2013, 6: 30. PMID: 23617957, PMCID: PMC3646677, DOI: 10.1186/1756-8722-6-30.
- P4‐009: A phosphoinositol modulator, synaptojanin 1, regulates amyloid homeostasisCai D, Zhu Z, Zhong M, Volpicelli‐Daley L, Liu L, Lucast L, De Camilli P. P4‐009: A phosphoinositol modulator, synaptojanin 1, regulates amyloid homeostasis. Alzheimer's & Dementia 2012, 8: p640-p641. DOI: 10.1016/j.jalz.2012.05.1710.
- Presenilin-1 uses phospholipase D1 as a negative regulator of β-amyloid formationCai D, Netzer WJ, Zhong M, Lin Y, Du G, Frohman M, Foster DA, Sisodia SS, Xu H, Gorelick FS, Greengard P. Presenilin-1 uses phospholipase D1 as a negative regulator of β-amyloid formation. Proceedings Of The National Academy Of Sciences Of The United States Of America 2006, 103: 1941-1946. PMID: 16449386, PMCID: PMC1413665, DOI: 10.1073/pnas.0510708103.
- Phospholipase D1 corrects impaired βAPP trafficking and neurite outgrowth in familial Alzheimer’s disease-linked presenilin-1 mutant neuronsCai D, Zhong M, Wang R, Netzer WJ, Shields D, Zheng H, Sisodia SS, Foster DA, Gorelick FS, Xu H, Greengard P. Phospholipase D1 corrects impaired βAPP trafficking and neurite outgrowth in familial Alzheimer’s disease-linked presenilin-1 mutant neurons. Proceedings Of The National Academy Of Sciences Of The United States Of America 2006, 103: 1936-1940. PMID: 16449385, PMCID: PMC1413666, DOI: 10.1073/pnas.0510710103.
- Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cellsZhong M, Shen Y, Zheng Y, Joseph T, Jackson D, Foster D. Phospholipase D prevents apoptosis in v-Src-transformed rat fibroblasts and MDA-MB-231 breast cancer cells. Biochemical And Biophysical Research Communications 2003, 302: 615-619. PMID: 12615079, DOI: 10.1016/s0006-291x(03)00229-8.
- Elevated phospholipase D activity induces apoptosis in normal rat fibroblastsZhong M, Joseph T, Jackson D, Beychenok S, Foster D. Elevated phospholipase D activity induces apoptosis in normal rat fibroblasts. Biochemical And Biophysical Research Communications 2002, 298: 474-477. PMID: 12408976, DOI: 10.1016/s0006-291x(02)02495-6.
- Downregulating PKC δ provides a PI3K/Akt-independent survival signal that overcomes apoptotic signals generated by c-Src overexpressionZhong M, Lu Z, Foster D. Downregulating PKC δ provides a PI3K/Akt-independent survival signal that overcomes apoptotic signals generated by c-Src overexpression. Oncogene 2002, 21: 1071-1078. PMID: 11850824, DOI: 10.1038/sj.onc.1205165.
- Transformation of Cells Overexpressing a Tyrosine Kinase by Phospholipase D1 and D2Joseph T, Wooden R, Bryant A, Zhong M, Lu Z, Foster D. Transformation of Cells Overexpressing a Tyrosine Kinase by Phospholipase D1 and D2. Biochemical And Biophysical Research Communications 2001, 289: 1019-1024. PMID: 11741292, DOI: 10.1006/bbrc.2001.6118.
- Novel tumor-promoting property of tamoxifen.Zhong M, Lu Z, Abbas T, Hornia A, Chatakondu K, Barile N, Kaplan P, Foster D. Novel tumor-promoting property of tamoxifen. Molecular Cancer Research 2001, 12: 187-92. PMID: 11331247.
- Phospholipase D and RalA Cooperate with the Epidermal Growth Factor Receptor To Transform 3Y1 Rat FibroblastsLu Z, Hornia A, Joseph T, Sukezane T, Frankel P, Zhong M, Bychenok S, Xu L, Feig L, Foster D. Phospholipase D and RalA Cooperate with the Epidermal Growth Factor Receptor To Transform 3Y1 Rat Fibroblasts. Molecular And Cellular Biology 2000, 20: 462-467. PMID: 10611224, PMCID: PMC85102, DOI: 10.1128/mcb.20.2.462-467.2000.
- Antagonistic Effects of Protein Kinase C α and δ on Both Transformation and Phospholipase D Activity Mediated by the Epidermal Growth Factor ReceptorHornia A, Lu Z, Sukezane T, Zhong M, Joseph T, Frankel P, Foster D. Antagonistic Effects of Protein Kinase C α and δ on Both Transformation and Phospholipase D Activity Mediated by the Epidermal Growth Factor Receptor. Molecular And Cellular Biology 1999, 19: 7672-7680. PMID: 10523655, PMCID: PMC84804, DOI: 10.1128/mcb.19.11.7672.