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Michelle Hampson, PhD

Associate Professor of Radiology and Biomedical Imaging; Director of real-time fMRI

Research Summary

My lab is focused on the development and application of new functional brain imaging paradigms. These include resting state functional connectivity analyses and neurofeedback via real-time fMRI (rt-fMRI). Rt-fMRI neurofeedback has great potential as a clinical treatment for mental and neurological disorders. When used in conjunction with resting state functional connectivity assessments (collected before and after the neurofeedback), it provides a powerful perturb-and-measure approach for studying human brain function.

Extensive Research Description

1. We use neurofeedback of real-time fMRI data to train patients with tic disorders, OCD, PTSD, and borderline personality disorder to control clinically relevant brain activity patterns. An important question is whether this training can improve their symptoms.

2. We evaluate changes in resting state functional connectivity between brain areas before and after neurofeedback. This allows us to investigate how neurofeedback alters brain networks. Also, by correlating changes in brain connectivity with symptom changes, we can gain insight into the neural circuitry that gives rise to symptoms.


Coauthors

Research Interests

Magnetic Resonance Imaging; Neurosciences; Obsessive-Compulsive Disorder; Stress Disorders, Post-Traumatic; Video Games; Neurofeedback; Psychiatry and Psychology

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Selected Publications

Clinical Trials

ConditionsStudy Title
Diseases of the Nervous SystemImaging dopamine mediated effects of stress on inhibitory control
Child Development & Autism; Diseases of the Nervous System; Genetics - Adult; Genetics - Pediatric; Mental Health & Behavioral ResearchGenetic and molecular studies of developmental neuropsychiatric disorders
Diseases of the Nervous System; Mental Health & Behavioral ResearchNeurofeedback of Amygdala Activity for Post-traumatic Stress Disorder (PTSD)
Mental Health & Behavioral ResearchKetamine in Borderline Personality Disorder
Child Development & Autism; Children's Health; Mental Health & Behavioral ResearchCBT for Anxiety in Children With Autism
Diseases of the Nervous System; Mental Health & Behavioral ResearchBiomarkers of Clinical Subtype and Treatment Response in Obsessive-Compulsive Disorder
Diseases of the Nervous System; Mental Health & Behavioral ResearchNeurofeedback for Obsessive-Compulsive Disorder