Research & Publications
Interactions between the skeletal, immune, and hematopoietic systems as they relate to normal and pathologic bone remodeling. Transgenic mice are used to investigate osteoblast and osteoclast development.
Specialized Terms: Osteoimmunology; Osteoblasts; Osteoclasts; Adipocytes; Bone remodeling; Mesenchymal stem cell differentiation; B cell transcription factors and bone
Extensive Research Description
- Analysis of the bone and fat phenotype of mice lacking the B cell transcription factors Ebf1 and Pax5
- Analysis of the bone phenotype of mice lacking GATA1
- Isolation and characterization of bone cells from inside bone (osteocytes).
- Develop mouse models for marrow fat.
Bone and Bones; Orthopedics; Osteoblasts; Osteoclasts; Bone Remodeling; Adipocytes; Mesenchymal Stem Cell Transplantation