Mark Estacion, PhD
Research Scientist
Research & Publications
Biography
News
Research Summary
My research interests are focused on detailed characterization of the role voltage-gated sodium channels play in neurological syndromes such as inflammatory and neuropathic pain.
Coauthors
Research Interests
Biophysics; Electrophysiology; Neurophysiology; Neurosciences; Physiology
Selected Publications
- NaV1.7 gain-of-function mutations as a continuum: A1632E displays physiological changes associated with erythromelalgia and paroxysmal extreme pain disorder mutations and produces symptoms of both disorders.Estacion M, Dib-Hajj SD, Benke PJ, Te Morsche RH, Eastman EM, Macala LJ, Drenth JP, Waxman SG. NaV1.7 gain-of-function mutations as a continuum: A1632E displays physiological changes associated with erythromelalgia and paroxysmal extreme pain disorder mutations and produces symptoms of both disorders. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience 2008, 28:11079-88.
- Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable.Dib-Hajj SD, Estacion M, Jarecki BW, Tyrrell L, Fischer TZ, Lawden M, Cummins TR, Waxman SG. Paroxysmal extreme pain disorder M1627K mutation in human Nav1.7 renders DRG neurons hyperexcitable. Molecular Pain 2008, 4:37.