Mark Mooseker, PhD
Research & Publications
Biography
News
Extensive Research Description
Our laboratory pursues questions regarding the molecular and functional organization of the cell’s cytoskeleton. The major thrust of current effort is focused on the molecular and functional characterization of actin-filament based molecular motors—i.e., myosins. To date, 24 structurally distinct, evolutionarily-ancient classes of this molecular motor (in addition to the familiar two-headed, filament forming myosins of muscle and nonmuscle cells) have been identified. In vertebrate cells, multiple myosins of multiple classes are expressed, and for most of these myosins little is known regarding their function, since most have only just been discovered. At present we are conducting studies on a number of the novel myosins identified by our laboratory.
Ongoing projects include the following: a) cell biological and molecular genetic assessment of novel myosin functions in selected cell lines; b) biochemical and biophysical assessment of mechano-chemical (motor) properties; c) characterization of myosin-dependent organelle transport and membrane traffic; d) phenotypic analysis of myosin mutants in mouse and Drosophila. Among the myosins recently characterized by our laboratory include five classes of motor myosins (I,V, VI, VII, and IX) that are target genes for well-characterized mutations in mouse and man.
A key hypothesis to be tested is that, while some of the myosins expressed in the cell are probably involved in motile phenomena such as organelle movement or endocytosis, others utilize their mechanochemical properties not to locomote but rather to mechanochemically modulate the biological activities of those proteins with which that motor interacts (e.g., a membrane pump or channel). Still other myosins are likely to be key players in a variety of signal transduction cascades based on the identification of a variety of protein domains (e.g., SH-3, pleckstrin homology, GAP domains) that have been identified within the tail (non-motor) domains of certain myosins.
Coauthors
Selected Publications
- Role of Myosin1a in regulated exocytosis of CFTR in villus enterocytesHoekstra N, Kravtsov D, Mooseker M, Ameen N. Role of Myosin1a in regulated exocytosis of CFTR in villus enterocytes. The FASEB Journal 2013, 27: 913.11-913.11. DOI: 10.1096/fasebj.27.1_supplement.913.11.
- Mo1821 Normalization of CFTR Brush Border Membrane Trafficking Defects in the Intestines of Myosin 1A/6 Double Mutant MiceHoekstra N, Mooseker M, Ameen N. Mo1821 Normalization of CFTR Brush Border Membrane Trafficking Defects in the Intestines of Myosin 1A/6 Double Mutant Mice. Gastroenterology 2012, 142: s-692-s-693. DOI: 10.1016/s0016-5085(12)62674-2.
- Myo2p, a class V myosin in budding yeast, associates with a large ribonucleic acid–protein complex that contains mRNAs and subunits of the RNA-processing bodyChang W, Zaarour RF, Reck-Peterson S, Rinn J, Singer RH, Snyder M, Novick P, Mooseker MS. Myo2p, a class V myosin in budding yeast, associates with a large ribonucleic acid–protein complex that contains mRNAs and subunits of the RNA-processing body. RNA 2008, 14: 491-502. PMID: 18218704, PMCID: PMC2248268, DOI: 10.1261/rna.665008.
- Roles for Drosophila melanogaster Myosin IB in Maintenance of Enterocyte Brush-Border Structure and Resistance to the Bacterial Pathogen Pseudomonas entomophilaHegan PS, Mermall V, Tilney LG, Mooseker MS. Roles for Drosophila melanogaster Myosin IB in Maintenance of Enterocyte Brush-Border Structure and Resistance to the Bacterial Pathogen Pseudomonas entomophila. Molecular Biology Of The Cell 2007, 18: 4625-4636. PMID: 17855510, PMCID: PMC2043548, DOI: 10.1091/mbc.e07-02-0191.
- Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow‐derived dendritic cellsHolt JP, Bottomly K, Mooseker MS. Assessment of myosin II, Va, VI and VIIa loss of function on endocytosis and endocytic vesicle motility in bone marrow‐derived dendritic cells. Cytoskeleton 2007, 64: 756-766. PMID: 17615572, DOI: 10.1002/cm.20220.
- Myosin 1E interacts with synaptojanin‐1 and dynamin and is involved in endocytosisKrendel M, Osterweil EK, Mooseker MS. Myosin 1E interacts with synaptojanin‐1 and dynamin and is involved in endocytosis. FEBS Letters 2007, 581: 644-650. PMID: 17257598, PMCID: PMC1861834, DOI: 10.1016/j.febslet.2007.01.021.
- The Structural And Functional Diversity Of The Myosin Family Of Actin-Based Molecular MotorsMooseker M, Foth B. The Structural And Functional Diversity Of The Myosin Family Of Actin-Based Molecular Motors. 2007, 7: 1-34. DOI: 10.1007/978-1-4020-6519-4_1.
- Modulation of Cell Adhesion and Motility in the Immune System by Myo1fKim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, Flavell RA. Modulation of Cell Adhesion and Motility in the Immune System by Myo1f. Science 2006, 314: 136-139. PMID: 17023661, DOI: 10.1126/science.1131920.
- The Tail Domain of Myosin Va Modulates Actin Binding to One Head*Olivares A, Chang W, Mooseker M, Hackney D, De La Cruz E. The Tail Domain of Myosin Va Modulates Actin Binding to One Head*. Journal Of Biological Chemistry 2006, 281: 31326-31336. DOI: 10.1016/s0021-9258(19)84045-0.
- Cell Polarity Protein Spa2P Associates With Proteins Involved In Actin Function In Saccharomyces CerevisiaeShih J, Reck-Peterson S, Newitt R, Mooseker M, Aebersold R, Herskowitz I. Cell Polarity Protein Spa2P Associates With Proteins Involved In Actin Function In Saccharomyces Cerevisiae. Molecular Biology Of The Cell 2005, 16: 4595-4608. PMID: 16030260, PMCID: PMC1237067, DOI: 10.1091/mbc.e05-02-0108.
- Myosin-1a Is Critical for Normal Brush Border Structure and CompositionTyska M, Mackey A, Huang J, Copeland N, Jenkins N, Mooseker M. Myosin-1a Is Critical for Normal Brush Border Structure and Composition. Molecular Biology Of The Cell 2005, 16: 2443-2457. PMID: 15758024, PMCID: PMC1087248, DOI: 10.1091/mbc.e04-12-1116.
- A role for myosin VI in postsynaptic structure and glutamate receptor endocytosisOsterweil E, Wells D, Mooseker M. A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis. Journal Of Cell Biology 2005, 168: 329-338. PMID: 15657400, PMCID: PMC2171578, DOI: 10.1083/jcb.200410091.
- A role for myosin-1A in the localization of a brush border disaccharidaseTyska M, Mooseker M. A role for myosin-1A in the localization of a brush border disaccharidase. Journal Of Cell Biology 2004, 165: 395-405. PMID: 15138292, PMCID: PMC2172191, DOI: 10.1083/jcb.200310031.
- Myosin-Va Binds to and Mechanochemically Couples Microtubules to Actin FilamentsCao T, Chang W, Masters S, Mooseker M. Myosin-Va Binds to and Mechanochemically Couples Microtubules to Actin Filaments. Molecular Biology Of The Cell 2003, 15: 151-161. PMID: 14565972, PMCID: PMC307536, DOI: 10.1091/mbc.e03-07-0504.
- Myosin-V motility: these levers were made for walkingTyska M, Mooseker M. Myosin-V motility: these levers were made for walking. Trends In Cell Biology 2003, 13: 447-451. PMID: 12946621, DOI: 10.1016/s0962-8924(03)00172-7.
- Native Myosin-IXb is a plus-, not a minus-end-directed motorO'Connell C, Mooseker M. Native Myosin-IXb is a plus-, not a minus-end-directed motor. Nature Cell Biology 2003, 5: 171-172. PMID: 12563277, DOI: 10.1038/ncb924.
- MYO1A (Brush Border Myosin I) Dynamics in the Brush Border of LLC-PK1-CL4 CellsTyska M, Mooseker M. MYO1A (Brush Border Myosin I) Dynamics in the Brush Border of LLC-PK1-CL4 Cells. Biophysical Journal 2002, 82: 1869-1883. PMID: 11916846, PMCID: PMC1301984, DOI: 10.1016/s0006-3495(02)75537-9.
- The Abl-related gene (Arg) nonreceptor tyrosine kinase uses two F-actin-binding domains to bundle F-actinWang Y, Miller A, Mooseker M, Koleske A. The Abl-related gene (Arg) nonreceptor tyrosine kinase uses two F-actin-binding domains to bundle F-actin. Proceedings Of The National Academy Of Sciences Of The United States Of America 2001, 98: 14865-14870. PMID: 11752434, PMCID: PMC64950, DOI: 10.1073/pnas.251249298.
- Myosin-I nomenclatureGillespie P, Albanesi J, Bähler M, Bement W, Berg J, Burgess D, Burnside B, Cheney R, Corey D, Coudrier E, de Lanerolle P, Hammer J, Hasson T, Holt J, Hudspeth AJ, Ikebe M, Kendrick-Jones J, Korn E, Li R, Mercer J, Milligan R, Mooseker M, Ostap E, Petit C, Pollard T, Sellers J, Soldati T, Titus M. Myosin-I nomenclature. Journal Of Cell Biology 2001, 155: 703-704. PMID: 11724811, PMCID: PMC2150864, DOI: 10.1083/jcb.200110032.
- High Affinity Binding of Brain Myosin-Va to F-actin Induced by Calcium in the Presence of ATP*Tauhata S, dos Santos D, Taylor E, Mooseker M, Larson R. High Affinity Binding of Brain Myosin-Va to F-actin Induced by Calcium in the Presence of ATP*. Journal Of Biological Chemistry 2001, 276: 39812-39818. PMID: 11517216, DOI: 10.1074/jbc.m102583200.
- The Yeast Class V Myosins, Myo2p and Myo4p, Are Nonprocessive Actin-Based MotorsReck-Peterson S, Tyska M, Novick P, Mooseker M. The Yeast Class V Myosins, Myo2p and Myo4p, Are Nonprocessive Actin-Based Motors. Journal Of Cell Biology 2001, 153: 1121-1126. PMID: 11381095, PMCID: PMC2174330, DOI: 10.1083/jcb.153.5.1121.
- Myosin-VIIb, a Novel Unconventional Myosin, Is a Constituent of Microvilli in Transporting EpitheliaChen Z, Hasson T, Zhang D, Schwender B, Derfler B, Mooseker M, Corey D. Myosin-VIIb, a Novel Unconventional Myosin, Is a Constituent of Microvilli in Transporting Epithelia. Genomics 2001, 72: 285-296. PMID: 11401444, DOI: 10.1006/geno.2000.6456.
- The light chain composition of chicken brain myosin‐Va: Calmodulin, myosin‐II essential light chains, and 8‐kDa dynein light chain/PINEspindola F, Suter D, Partata L, Cao T, Wolenski J, Cheney R, King S, Mooseker M. The light chain composition of chicken brain myosin‐Va: Calmodulin, myosin‐II essential light chains, and 8‐kDa dynein light chain/PIN. Cytoskeleton 2000, 47: 269-281. PMID: 11093248, DOI: 10.1002/1097-0169(200012)47:4<269::aid-cm2>3.0.co;2-g.
- Myosin-V stepping kinetics: A molecular model for processivityRief M, Rock R, Mehta A, Mooseker M, Cheney R, Spudich J. Myosin-V stepping kinetics: A molecular model for processivity. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 9482-9486. PMID: 10944217, PMCID: PMC16890, DOI: 10.1073/pnas.97.17.9482.
- Role of Actin and Myo2p in Polarized Secretion and Growth ofSaccharomyces cerevisiaeKarpova T, Reck-Peterson S, Elkind N, Mooseker M, Novick P, Cooper J. Role of Actin and Myo2p in Polarized Secretion and Growth ofSaccharomyces cerevisiae. Molecular Biology Of The Cell 2000, 11: 1727-1737. PMID: 10793147, PMCID: PMC14879, DOI: 10.1091/mbc.11.5.1727.
- Compartmentalization of the Cell Cortex by Septins Is Required for Maintenance of Cell Polarity in YeastBarral Y, Mermall V, Mooseker M, Snyder M. Compartmentalization of the Cell Cortex by Septins Is Required for Maintenance of Cell Polarity in Yeast. Molecular Cell 2000, 5: 841-851. PMID: 10882120, DOI: 10.1016/s1097-2765(00)80324-x.
- The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5aJones J, Huang J, Mermall V, Hamilton B, Mooseker M, Escayg A, Copeland N, Jenkins N, Meisler M. The mouse neurological mutant flailer expresses a novel hybrid gene derived by exon shuffling between Gnb5 and Myo5a. Human Molecular Genetics 2000, 9: 821-828. PMID: 10749990, DOI: 10.1093/hmg/9.5.821.
- Class V myosinsReck-Peterson S, Provance D, Mooseker M, Mercer J. Class V myosins. Biochimica Et Biophysica Acta 2000, 1496: 36-51. PMID: 10722875, DOI: 10.1016/s0167-4889(00)00007-0.
- Localization of unconventional myosins V and VI in neuronal growth conesSuter D, Espindola F, Lin C, Forscher P, Mooseker M. Localization of unconventional myosins V and VI in neuronal growth cones. Developmental Neurobiology 2000, 42: 370-382. PMID: 10645976, DOI: 10.1002/(sici)1097-4695(20000215)42:3<370::aid-neu8>3.0.co;2-v.
- An invasion-associated Salmonella protein modulates the actin-bundling activity of plastinZhou D, Mooseker M, Galán J. An invasion-associated Salmonella protein modulates the actin-bundling activity of plastin. Proceedings Of The National Academy Of Sciences Of The United States Of America 1999, 96: 10176-10181. PMID: 10468582, PMCID: PMC17862, DOI: 10.1073/pnas.96.18.10176.
- Myosin-V is a processive actin-based motorMehta A, Rock R, Rief M, Spudich J, Mooseker M, Cheney R. Myosin-V is a processive actin-based motor. Nature 1999, 400: 590-593. PMID: 10448864, DOI: 10.1038/23072.
- The Tail of a Yeast Class V Myosin, Myo2p, Functions as a Localization DomainReck-Peterson S, Novick P, Mooseker M. The Tail of a Yeast Class V Myosin, Myo2p, Functions as a Localization Domain. Molecular Biology Of The Cell 1999, 10: 1001-1017. PMID: 10198053, PMCID: PMC25227, DOI: 10.1091/mbc.10.4.1001.
- Role of the S. typhimurium Actin-Binding Protein SipA in Bacterial InternalizationZhou D, Mooseker M, Galán J. Role of the S. typhimurium Actin-Binding Protein SipA in Bacterial Internalization. Science 1999, 283: 2092-2095. PMID: 10092234, DOI: 10.1126/science.283.5410.2092.
- A contractile activity that closes phagosomes in macrophagesSwanson J, Johnson M, Beningo K, Post P, Mooseker M, Araki N. A contractile activity that closes phagosomes in macrophages. Journal Of Cell Science 1999, 112: 307-316. PMID: 9885284, DOI: 10.1242/jcs.112.3.307.
- Cloning and characterization of mouse brush border myosin‐I in adult and embryonic intestineSkowron J, Mooseker M. Cloning and characterization of mouse brush border myosin‐I in adult and embryonic intestine. Journal Of Experimental Zoology 1999, 283: 242-257. PMID: 9933937, DOI: 10.1002/(sici)1097-010x(19990215)283:3<242::aid-jez3>3.0.co;2-f.
- Human brush border myosin‐I and myosin‐Ic expression in human intestine and Caco‐2BBe cellsSkowron J, Bement W, Mooseker M. Human brush border myosin‐I and myosin‐Ic expression in human intestine and Caco‐2BBe cells. Cytoskeleton 1998, 41: 308-324. PMID: 9858156, DOI: 10.1002/(sici)1097-0169(1998)41:4<308::aid-cm4>3.0.co;2-j.
- Vesicle-associated brain myosin-V can be activated to catalyze actin-based transportEvans L, Lee A, Bridgman P, Mooseker M. Vesicle-associated brain myosin-V can be activated to catalyze actin-based transport. Journal Of Cell Science 1998, 111: 2055-2066. PMID: 9645952, DOI: 10.1242/jcs.111.14.2055.
- Human myosin-IXb is a mechanochemically active motor and a GAP for rhoPost P, Bokoch G, Mooseker M. Human myosin-IXb is a mechanochemically active motor and a GAP for rho. Journal Of Cell Science 1998, 111: 941-950. PMID: 9490638, DOI: 10.1242/jcs.111.7.941.
- Molecular Genetic Dissection of Mouse Unconventional Myosin-VA: Head Region MutationsHuang J, Cope M, Mermall V, Strobel M, Kendrick-Jones J, Russell L, Mooseker M, Copeland N, Jenkins N. Molecular Genetic Dissection of Mouse Unconventional Myosin-VA: Head Region Mutations. Genetics 1998, 148: 1951-1961. PMID: 9560408, PMCID: PMC1460099, DOI: 10.1093/genetics/148.4.1951.
- Molecular Genetic Dissection of Mouse Unconventional Myosin-VA: Tail Region MutationsHuang J, Mermall V, Strobel M, Russell L, Mooseker M, Copeland N, Jenkins N. Molecular Genetic Dissection of Mouse Unconventional Myosin-VA: Tail Region Mutations. Genetics 1998, 148: 1963-1972. PMID: 9560409, PMCID: PMC1460104, DOI: 10.1093/genetics/148.4.1963.
- Unconventional Myosins in Cell Movement, Membrane Traffic, and Signal TransductionMermall V, Post P, Mooseker M. Unconventional Myosins in Cell Movement, Membrane Traffic, and Signal Transduction. Science 1998, 279: 527-533. PMID: 9438839, DOI: 10.1126/science.279.5350.527.
- The growing family of myosin motors and their role in neurons and sensory cellsHasson T, Mooseker M. The growing family of myosin motors and their role in neurons and sensory cells. Current Opinion In Neurobiology 1997, 7: 615-623. PMID: 9384540, DOI: 10.1016/s0959-4388(97)80080-3.
- An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatinFrankel S, Sigel E, Craig C, Elgin S, Mooseker M, Artavanis-Tsakonas S. An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin. Journal Of Cell Science 1997, 110: 1999-2012. PMID: 9378752, DOI: 10.1242/jcs.110.17.1999.
- Unconventional Myosins in Inner-Ear Sensory EpitheliaHasson T, Gillespie P, Garcia J, MacDonald R, Zhao Y, Yee A, Mooseker M, Corey D. Unconventional Myosins in Inner-Ear Sensory Epithelia. Journal Of Cell Biology 1997, 137: 1287-1307. PMID: 9182663, PMCID: PMC2132524, DOI: 10.1083/jcb.137.6.1287.
- The Genomic Structure of the Gene Defective in Usher Syndrome Type Ib (MYO7A)Kelley P, Weston M, Chen Z, Orten D, Hasson T, Overbeck L, Pinnt J, Talmadge C, Ing P, Mooseker M, Corey D, Sumegi J, Kimberling W. The Genomic Structure of the Gene Defective in Usher Syndrome Type Ib (MYO7A). Genomics 1997, 40: 73-79. PMID: 9070921, DOI: 10.1006/geno.1996.4545.
- Effects of shaker‐1 mutations on myosin‐VIIa protein and mRNA expressionHasson T, Walsh J, Cable J, Mooseker M, Brown S, Steel K. Effects of shaker‐1 mutations on myosin‐VIIa protein and mRNA expression. Cytoskeleton 1997, 37: 127-138. PMID: 9186010, DOI: 10.1002/(sici)1097-0169(1997)37:2<127::aid-cm5>3.0.co;2-5.
- Actin-binding membrane proteins identified by F-actin blot overlays.Luna E, Pestonjamasp K, Cheney R, Strassel C, Lu T, Chia C, Hitt A, Fechheimer M, Furthmayr H, Mooseker M. Actin-binding membrane proteins identified by F-actin blot overlays. Society Of General Physiologists Series 1997, 52: 3-18. PMID: 9210216.
- Myosin VIIA mutation screening in 189 Usher syndrome type 1 patients.Weston M, Kelley P, Overbeck L, Wagenaar M, Orten D, Hasson T, Chen Z, Corey D, Mooseker M, Sumegi J, Cremers C, Moller C, Jacobson S, Gorin M, Kimberling W. Myosin VIIA mutation screening in 189 Usher syndrome type 1 patients. American Journal Of Human Genetics 1996, 59: 1074-83. PMID: 8900236, PMCID: PMC1914835.
- Mapping of Unconventional Myosins in Mouse and HumanHasson T, Skowron J, Gilbert D, Avraham K, Perry W, Bement W, Anderson B, Sherr E, Chen Z, Greene L, Ward D, Corey D, Mooseker M, Copeland N, Jenkins N. Mapping of Unconventional Myosins in Mouse and Human. Genomics 1996, 36: 431-439. PMID: 8884266, DOI: 10.1006/geno.1996.0488.
- Molecular Cloning and Domain Structure of Human Myosin-VIIa, the Gene Product Defective in Usher Syndrome 1BChen Z, Hasson T, Kelley P, Schwender B, Schwartz M, Ramakrishnan M, Kimberling W, Mooseker M, Corey D. Molecular Cloning and Domain Structure of Human Myosin-VIIa, the Gene Product Defective in Usher Syndrome 1B. Genomics 1996, 36: 440-448. PMID: 8884267, DOI: 10.1006/geno.1996.0489.
- Function of Myosin-V in Filopodial Extension of Neuronal Growth ConesWang F, Wolenski J, Cheney R, Mooseker M, Jay D. Function of Myosin-V in Filopodial Extension of Neuronal Growth Cones. Science 1996, 273: 660-663. PMID: 8662560, DOI: 10.1126/science.273.5275.660.
- Vertebrate Unconventional MyosinsHasson T, Mooseker M. Vertebrate Unconventional Myosins. Journal Of Biological Chemistry 1996, 271: 16434. PMID: 8663497.
- Enzymatic Characterization and Functional Domain Mapping of Brain Myosin-V*Nascimento A, Cheney R, Tauhata S, Larson R, Mooseker M. Enzymatic Characterization and Functional Domain Mapping of Brain Myosin-V*. Journal Of Biological Chemistry 1996, 271: 17561-17569. PMID: 8663447, DOI: 10.1074/jbc.271.29.17561.
- Vertebrate Unconventional Myosins*Hasson T, Mooseker M. Vertebrate Unconventional Myosins*. Journal Of Biological Chemistry 1996, 271: 16431-16434. PMID: 8690736, DOI: 10.1074/jbc.271.28.16431.
- Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tailWirth J, Jensen K, Post P, Bement W, Mooseker M. Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail. Journal Of Cell Science 1996, 109: 653-661. PMID: 8907710, DOI: 10.1242/jcs.109.3.653.
- The actin-related proteinsFrankel S, Mooseker M. The actin-related proteins. Current Opinion In Cell Biology 1996, 8: 30-37. PMID: 8791406, DOI: 10.1016/s0955-0674(96)80045-7.
- The cytoskeleton of the intestinal epithelium Components, assembly, and dynamic rearrangementsBement W, Mooseker M. The cytoskeleton of the intestinal epithelium Components, assembly, and dynamic rearrangements. 1996, 3: 359-404. DOI: 10.1016/s1874-6020(96)80015-2.
- The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cellsAvraham K, Hasson T, Steel K, Kingsley D, Russell L, Mooseker M, Copeland N, Jenkins N. The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells. Nature Genetics 1995, 11: 369-375. PMID: 7493015, DOI: 10.1038/ng1295-369.
- Characterization of Myosin-IA and Myosin-IB, Two Unconventional Myosins Associated with theDrosophilaBrush Border CytoskeletonMorgan N, Heintzelman M, Mooseker M. Characterization of Myosin-IA and Myosin-IB, Two Unconventional Myosins Associated with theDrosophilaBrush Border Cytoskeleton. Developmental Biology 1995, 172: 51-71. PMID: 7589814, DOI: 10.1006/dbio.1995.0005.
- Unconventional MyosinsMooseker M, Cheney R. Unconventional Myosins. Annual Review Of Cell And Developmental Biology 1995, 11: 633-675. PMID: 8689571, DOI: 10.1146/annurev.cb.11.110195.003221.
- Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B.Hasson T, Heintzelman M, Santos-Sacchi J, Corey D, Mooseker M. Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B. Proceedings Of The National Academy Of Sciences Of The United States Of America 1995, 92: 9815-9819. PMID: 7568224, PMCID: PMC40893, DOI: 10.1073/pnas.92.21.9815.
- Molecular motors, membrane movements and physiology: emerging roles for myosinsHasson T, Mooseker M. Molecular motors, membrane movements and physiology: emerging roles for myosins. Current Opinion In Cell Biology 1995, 7: 587-594. PMID: 7495580, DOI: 10.1016/0955-0674(95)80017-4.
- TEDS rule: A molecular rationale for differential regulation of myosins by phosphorylation of the heavy chain headBement W, Mooseker M. TEDS rule: A molecular rationale for differential regulation of myosins by phosphorylation of the heavy chain head. Cytoskeleton 1995, 31: 87-92. PMID: 7553910, DOI: 10.1002/cm.970310202.
- Multiple unconventional myosin domains of the intestinal brush border cytoskeletonHeintzelman M, Hasson T, Mooseker M. Multiple unconventional myosin domains of the intestinal brush border cytoskeleton. Journal Of Cell Science 1994, 107: 3535-3543. PMID: 7706404, DOI: 10.1242/jcs.107.12.3535.
- Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.Bement W, Hasson T, Wirth J, Cheney R, Mooseker M. Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types. Proceedings Of The National Academy Of Sciences Of The United States Of America 1994, 91: 11767. PMID: 7972138, PMCID: PMC55655, DOI: 10.1073/pnas.91.24.11767-c.
- Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.Bement W, Hasson T, Wirth J, Cheney R, Mooseker M. Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types. Proceedings Of The National Academy Of Sciences Of The United States Of America 1994, 91: 11767. DOI: 10.1073/pnas.91.24.11767-c.
- Porcine myosin-VI: characterization of a new mammalian unconventional myosin.Hasson T, Mooseker M. Porcine myosin-VI: characterization of a new mammalian unconventional myosin. Journal Of Cell Biology 1994, 127: 425-440. PMID: 7929586, PMCID: PMC2120210, DOI: 10.1083/jcb.127.2.425.
- Cloning and mRNA Expression of Human Unconventional Myosin-IC A Homologue of Amoeboid Myosins-I With a Single IQ Motif and an SH3 DomainBement W, Wirth J, Mooseker M. Cloning and mRNA Expression of Human Unconventional Myosin-IC A Homologue of Amoeboid Myosins-I With a Single IQ Motif and an SH3 Domain. Journal Of Molecular Biology 1994, 243: 356-363. PMID: 7932763, DOI: 10.1006/jmbi.1994.1662.
- Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.Bement W, Hasson T, Wirth J, Cheney R, Mooseker M. Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types. Proceedings Of The National Academy Of Sciences Of The United States Of America 1994, 91: 6549-6553. PMID: 8022818, PMCID: PMC44240, DOI: 10.1073/pnas.91.14.6549.
- The Molecular Cloning and Characterization of Drosophila melanogaster Myosin-IA and Myosin-IBMorgan N, Skovronsky D, Artavanis-Tsakonas S, Mooseker M. The Molecular Cloning and Characterization of Drosophila melanogaster Myosin-IA and Myosin-IB. Journal Of Molecular Biology 1994, 239: 347-356. PMID: 8201616, DOI: 10.1006/jmbi.1994.1376.
- Editorial overviewCleveland D, Mooseker M. Editorial overview. Current Opinion In Cell Biology 1994, 6: 1-2. DOI: 10.1016/0955-0674(94)90108-2.
- Identification of a Divergent Actin-related Protein in DrosophilaFrankel S, Heintzelman M, Artavanis-Tsakonas S, Mooseker M. Identification of a Divergent Actin-related Protein in Drosophila. Journal Of Molecular Biology 1994, 235: 1351-1356. PMID: 8308899, DOI: 10.1006/jmbi.1994.1090.
- Differential regulation of skeletal muscle myosin‐II and brush border myosin‐I enzymology and mechanochemistry by bacterially produced tropomyosin isoformsFanning A, Wolenski J, Mooseker M, Izant J. Differential regulation of skeletal muscle myosin‐II and brush border myosin‐I enzymology and mechanochemistry by bacterially produced tropomyosin isoforms. Cytoskeleton 1994, 29: 29-45. PMID: 7820856, DOI: 10.1002/cm.970290104.
- Keeping out the rainBement W, Mooseker M. Keeping out the rain. Nature 1993, 365: 785-786. PMID: 8413662, DOI: 10.1038/365785a0.
- Brain myosin-V is a two-headed unconventional myosin with motor activityCheney R, O'Shea M, Heuser J, Coelho M, Wolenski J, Espreafico E, Forscher P, Larson R, Mooseker M. Brain myosin-V is a two-headed unconventional myosin with motor activity. Cell 1993, 75: 13-23. PMID: 8402892, DOI: 10.1016/s0092-8674(05)80080-7.
- In vitro motilities of the unconventional myosins, brush border myosin‐I, and chick brain myosin‐V exhibit assay‐dependent differences in velocityWolenski J, Cheney R, Forscher P, Mooseker M. In vitro motilities of the unconventional myosins, brush border myosin‐I, and chick brain myosin‐V exhibit assay‐dependent differences in velocity. Journal Of Experimental Zoology 1993, 267: 33-39. PMID: 8376949, DOI: 10.1002/jez.1402670106.
- Calcium-calmodulin and regulation of brush border myosin-I MgATPase and mechanochemistryWolenski J, Hayden S, Forscher P, Mooseker. Calcium-calmodulin and regulation of brush border myosin-I MgATPase and mechanochemistry. Journal Of Cell Biology 1993, 122: 613-621. PMID: 8335688, PMCID: PMC2119657, DOI: 10.1083/jcb.122.3.613.
- An in vitro model for the analysis of intestinal brush border assembly I. Ultrastructural analysis of cell contact-induced brush border assembly in Caco-2BBe cellsPeterson M, Mooseker M. An in vitro model for the analysis of intestinal brush border assembly I. Ultrastructural analysis of cell contact-induced brush border assembly in Caco-2BBe cells. Journal Of Cell Science 1993, 105: 445-460. PMID: 8408276, DOI: 10.1242/jcs.105.2.445.
- An in vitro model for the analysis of intestinal brush border assembly. II. Changes in expression and localization of brush border proteins during cell contact-induced brush border assembly in Caco-2BBe cells.Peterson M, Bement W, Mooseker M. An in vitro model for the analysis of intestinal brush border assembly. II. Changes in expression and localization of brush border proteins during cell contact-induced brush border assembly in Caco-2BBe cells. Journal Of Cell Science 1993, 105 ( Pt 2): 461-72. PMID: 8408277, DOI: 10.1242/jcs.105.2.461.
- Cloning of a Secretory Gelsolin from Drosophila melanogasterHeintzelman M, Frankel S, Artavanis-Tsakonas S, Mooseker M. Cloning of a Secretory Gelsolin from Drosophila melanogaster. Journal Of Molecular Biology 1993, 230: 709-716. PMID: 8386771, DOI: 10.1006/jmbi.1993.1191.
- A multitude of myosinsMooseker M. A multitude of myosins. Current Biology 1993, 3: 245-248. PMID: 15335779, DOI: 10.1016/0960-9822(93)90346-p.
- Phylogenetic analysis of the myosin superfamilyCheney R, Riley M, Mooseker M. Phylogenetic analysis of the myosin superfamily. Cytoskeleton 1993, 24: 215-223. PMID: 8477454, DOI: 10.1002/cm.970240402.
- Biochemical and immunological characterization of p190-calmodulin complex from vertebrate brain: a novel calmodulin-binding myosin.Espindola F, Espreafico E, Coelho M, Martins A, Costa F, Mooseker M, Larson R. Biochemical and immunological characterization of p190-calmodulin complex from vertebrate brain: a novel calmodulin-binding myosin. Journal Of Cell Biology 1992, 118: 359-368. PMID: 1378447, PMCID: PMC2290054, DOI: 10.1083/jcb.118.2.359.
- Localization of capping protein in chicken epithelial cells by immunofluorescence and biochemical fractionation.Schafer D, Mooseker M, Cooper J. Localization of capping protein in chicken epithelial cells by immunofluorescence and biochemical fractionation. Journal Of Cell Biology 1992, 118: 335-346. PMID: 1629237, PMCID: PMC2290044, DOI: 10.1083/jcb.118.2.335.
- Characterization of the enterocyte-like brush border cytoskeleton of the C2BBe clones of the human intestinal cell line, Caco-2Peterson M, Mooseker M. Characterization of the enterocyte-like brush border cytoskeleton of the C2BBe clones of the human intestinal cell line, Caco-2. Journal Of Cell Science 1992, 102: 581-600. PMID: 1506435, DOI: 10.1242/jcs.102.3.581.
- The molecular architecture of an insect midgut brush border cytoskeleton.Bonfanti P, Colombo A, Heintzelman M, Mooseker M, Camatini M. The molecular architecture of an insect midgut brush border cytoskeleton. European Journal Of Cell Biology 1992, 57: 298-307. PMID: 1511705.
- Unconventional myosinsCheney R, Mooseker M. Unconventional myosins. Current Opinion In Cell Biology 1992, 4: 27-35. PMID: 1558751, DOI: 10.1016/0955-0674(92)90055-h.
- 6 Assembly of the Intestinal Brush Border CytoskeletonHeintzelman M, Mooseker M. 6 Assembly of the Intestinal Brush Border Cytoskeleton. 1992, 26: 93-122. PMID: 1563281, DOI: 10.1016/s0070-2153(08)60442-1.
- Enterocyte Cytoskeleton: Its Structure and FunctionKeller T, Mooseker M. Enterocyte Cytoskeleton: Its Structure and Function. 1991, 209-221. DOI: 10.1002/cphy.cp060406.
- Chapter 3 Structural and Functional Dissection of a Membrane-Bound Mechanoenzyme: Brush Border Myosin IMooseker M, Wolenski J, Coleman T, Hayden S, Cheney R, Espreafico E, Heintzelman M, Peterson M. Chapter 3 Structural and Functional Dissection of a Membrane-Bound Mechanoenzyme: Brush Border Myosin I. 1991, 38: 31-55. DOI: 10.1016/s0070-2161(08)60780-7.
- PrefaceMooseker M, Morrow J. Preface. 1991, 38: xvii-xviii. DOI: 10.1016/s0070-2161(08)60777-7.
- Structural and functional analysis of the 110 kD protein (BBMI) from the brush border enterocytesCoudrier E, Garcia A, Carboni J, Anderson J, Landry C, Huet C, Vanderkerhove J, Mooseker M, Arpin M, Louvard D. Structural and functional analysis of the 110 kD protein (BBMI) from the brush border enterocytes. Cell Biology International 1990, 14: 136. DOI: 10.1016/0309-1651(90)90644-e.
- Binding of brush border myosin I to phospholipid vesicles.Hayden S, Wolenski J, Mooseker M. Binding of brush border myosin I to phospholipid vesicles. Journal Of Cell Biology 1990, 111: 443-451. PMID: 2143194, PMCID: PMC2116197, DOI: 10.1083/jcb.111.2.443.
- Structural and compositional analysis of early stages in microvillus assembly in the enterocyte of the chick embryoHeintzelman M, Mooseker M. Structural and compositional analysis of early stages in microvillus assembly in the enterocyte of the chick embryo. Differentiation 1990, 43: 175-182. PMID: 2387484, DOI: 10.1111/j.1432-0436.1990.tb00444.x.
- Assembly of the brush border cytoskeleton: Changes in the distribution of microvillar core proteins during enterocyte differentiation in adult chicken intestineHeintzelman M, Mooseker M. Assembly of the brush border cytoskeleton: Changes in the distribution of microvillar core proteins during enterocyte differentiation in adult chicken intestine. Cytoskeleton 1990, 15: 12-22. PMID: 2403846, DOI: 10.1002/cm.970150104.
- Partial deduced sequence of the 110-kD-calmodulin complex of the avian intestinal microvillus shows that this mechanoenzyme is a member of the myosin I family.Garcia A, Coudrier E, Carboni J, Anderson J, Vandekerkhove J, Mooseker M, Louvard D, Arpin M. Partial deduced sequence of the 110-kD-calmodulin complex of the avian intestinal microvillus shows that this mechanoenzyme is a member of the myosin I family. Journal Of Cell Biology 1989, 109: 2895-2903. PMID: 2687288, PMCID: PMC2115973, DOI: 10.1083/jcb.109.6.2895.
- Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistanceStevenson B, Anderson J, Braun I, Mooseker M. Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance. Biochemical Journal 1989, 263: 597-599. PMID: 2597123, PMCID: PMC1133468, DOI: 10.1042/bj2630597.
- ZO-1 and cingulin: tight junction proteins with distinct identities and localizationsStevenson B, Heintzelman M, Anderson J, Citi S, Mooseker M. ZO-1 and cingulin: tight junction proteins with distinct identities and localizations. American Journal Of Physiology 1989, 257: c621-c628. PMID: 2679124, DOI: 10.1152/ajpcell.1989.257.4.c621.
- Characterization of intestinal microvillar membrane disks: detergent-resistant membrane sheets enriched in associated brush border myosin I (110K-calmodulin).Mooseker M, Conzelman K, Coleman T, Heuser J, Sheetz M. Characterization of intestinal microvillar membrane disks: detergent-resistant membrane sheets enriched in associated brush border myosin I (110K-calmodulin). Journal Of Cell Biology 1989, 109: 1153-1161. PMID: 2527857, PMCID: PMC2115773, DOI: 10.1083/jcb.109.3.1153.
- ZO-1 mRNA and protein expression during tight junction assembly in Caco-2 cells.Anderson J, Van Itallie C, Peterson M, Stevenson B, Carew E, Mooseker M. ZO-1 mRNA and protein expression during tight junction assembly in Caco-2 cells. Journal Of Cell Biology 1989, 109: 1047-1056. PMID: 2670954, PMCID: PMC2115763, DOI: 10.1083/jcb.109.3.1047.
- Molecular analysis of the tight junctionStevenson B, Heintzelman M, Anderson J, Citi S, Braun I, Mooseker M. Molecular analysis of the tight junction. Microscopy And Microanalysis 1989, 47: 810-811. DOI: 10.1017/s042482010015602x.
- Myosin linkage strengthenedMooseker M. Myosin linkage strengthened. Nature 1989, 340: 505-505. PMID: 2770856, DOI: 10.1038/340505a0.
- The 110-kD protein-calmodulin complex of the intestinal microvillus (brush border myosin I) is a mechanoenzyme.Mooseker M, Coleman T. The 110-kD protein-calmodulin complex of the intestinal microvillus (brush border myosin I) is a mechanoenzyme. Journal Of Cell Biology 1989, 108: 2395-2400. PMID: 2525564, PMCID: PMC2115599, DOI: 10.1083/jcb.108.6.2395.
- Hepatic immunohistochemical localization of the tight junction protein ZO-1 in rat models of cholestasis.Anderson J, Glade J, Stevenson B, Boyer J, Mooseker M. Hepatic immunohistochemical localization of the tight junction protein ZO-1 in rat models of cholestasis. American Journal Of Pathology 1989, 134: 1055-62. PMID: 2719075, PMCID: PMC1879891.
- Contributions of the β‐subunit to spectrin structure and functionColeman T, Fishkind D, Mooseker M, Morrow J. Contributions of the β‐subunit to spectrin structure and function. Cytoskeleton 1989, 12: 248-263. PMID: 2524283, DOI: 10.1002/cm.970120406.
- Functional diversity among spectrin isoformsColeman T, Fishkind D, Mooseker M, Morrow J. Functional diversity among spectrin isoforms. Cytoskeleton 1989, 12: 225-247. PMID: 2655937, DOI: 10.1002/cm.970120405.
- Tight junction structure and ZO-1 content are identical in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance.Stevenson B, Anderson J, Goodenough D, Mooseker M. Tight junction structure and ZO-1 content are identical in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance. Journal Of Cell Biology 1988, 107: 2401-2408. PMID: 3058723, PMCID: PMC2115690, DOI: 10.1083/jcb.107.6.2401.
- Characterization of ZO-1, a protein component of the tight junction from mouse liver and Madin-Darby canine kidney cells.Anderson J, Stevenson B, Jesaitis L, Goodenough D, Mooseker M. Characterization of ZO-1, a protein component of the tight junction from mouse liver and Madin-Darby canine kidney cells. Journal Of Cell Biology 1988, 106: 1141-1149. PMID: 2452168, PMCID: PMC2115004, DOI: 10.1083/jcb.106.4.1141.
- Localization of villin, a cytoskeletal protein specific to microvilli, in human ileum and colon and in colonic neoplasmsWest A, Isaac C, Carboni J, Morrow J, Mooseker M, Barwick K. Localization of villin, a cytoskeletal protein specific to microvilli, in human ileum and colon and in colonic neoplasms. Gastroenterology 1988, 94: 343-352. PMID: 3335311, DOI: 10.1016/0016-5085(88)90421-0.
- Characterization of villin from the intestinal brush border of the rat, and comparative analysis with avian villinAlicea H, Mooseker M. Characterization of villin from the intestinal brush border of the rat, and comparative analysis with avian villin. Cytoskeleton 1988, 9: 60-72. PMID: 3356045, DOI: 10.1002/cm.970090107.
- A domain of synapsin I involved with actin bundling shares immunologic cross‐reactivity with villinPetrucci T, Mooseker M, Morrow J. A domain of synapsin I involved with actin bundling shares immunologic cross‐reactivity with villin. Journal Of Cellular Biochemistry 1988, 36: 25-35. PMID: 3125185, DOI: 10.1002/jcb.240360104.
- Erythrocyte adducin: a calmodulin-regulated actin-bundling protein that stimulates spectrin-actin binding.Mische S, Mooseker M, Morrow J. Erythrocyte adducin: a calmodulin-regulated actin-bundling protein that stimulates spectrin-actin binding. Journal Of Cell Biology 1987, 105: 2837-2845. PMID: 3693401, PMCID: PMC2114693, DOI: 10.1083/jcb.105.6.2837.
- Characterization of intestinal brush border cytoskeletal proteins of normal and neoplastic human epithelial cells. A comparison with the avian brush border.Carboni J, Howe C, West A, Barwick K, Mooseker M, Morrow J. Characterization of intestinal brush border cytoskeletal proteins of normal and neoplastic human epithelial cells. A comparison with the avian brush border. American Journal Of Pathology 1987, 129: 589-600. PMID: 3425692, PMCID: PMC1899811.
- Assembly of the intestinal brush border: appearance and redistribution of microvillar core proteins in developing chick enterocytes.Shibayama T, Carboni J, Mooseker M. Assembly of the intestinal brush border: appearance and redistribution of microvillar core proteins in developing chick enterocytes. Journal Of Cell Biology 1987, 105: 335-344. PMID: 2956268, PMCID: PMC2114914, DOI: 10.1083/jcb.105.1.335.
- The 110-kD protein-calmodulin complex of the intestinal microvillus is an actin-activated MgATPase.Conzelman K, Mooseker M. The 110-kD protein-calmodulin complex of the intestinal microvillus is an actin-activated MgATPase. Journal Of Cell Biology 1987, 105: 313-324. PMID: 2956266, PMCID: PMC2114910, DOI: 10.1083/jcb.105.1.313.
- Nucleation of actin polymerization by villin and elongation at subcritical monomer concentration.Weber A, Northrop J, Bishop M, Ferrone F, Mooseker M. Nucleation of actin polymerization by villin and elongation at subcritical monomer concentration. Biochemistry 1987, 26: 2528-36. PMID: 3607030, DOI: 10.1021/bi00383a019.
- Kinetics of actin elongation and depolymerization at the pointed end.Weber A, Northrop J, Bishop M, Ferrone F, Mooseker M. Kinetics of actin elongation and depolymerization at the pointed end. Biochemistry 1987, 26: 2537-44. PMID: 3607031, DOI: 10.1021/bi00383a020.
- Beta spectrin bestows protein 4.1 sensitivity on spectrin-actin interactions.Coleman T, Harris A, Mische S, Mooseker M, Morrow J. Beta spectrin bestows protein 4.1 sensitivity on spectrin-actin interactions. Journal Of Cell Biology 1987, 104: 519-526. PMID: 3818791, PMCID: PMC2114562, DOI: 10.1083/jcb.104.3.519.
- Cytoskeletal proteins of the rat kidney proximal tubule brush border.Rodman J, Mooseker M, Farquhar M. Cytoskeletal proteins of the rat kidney proximal tubule brush border. European Journal Of Cell Biology 1986, 42: 319-27. PMID: 3545840.
- Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.Stevenson B, Siliciano J, Mooseker M, Goodenough D. Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia. Journal Of Cell Biology 1986, 103: 755-766. PMID: 3528172, PMCID: PMC2114282, DOI: 10.1083/jcb.103.3.755.
- Different calcium dependence of the capping and cutting activities of villin.Northrop J, Weber A, Mooseker M, Franzini-Armstrong C, Bishop M, Dubyak G, Tucker M, Walsh T. Different calcium dependence of the capping and cutting activities of villin. Journal Of Biological Chemistry 1986, 261: 9274-9281. PMID: 3087992, DOI: 10.1016/s0021-9258(18)67650-1.
- Calcium and the Regulation of Cytoskeletal Assembly, Structure and ContractilityMooseker M, Coleman T, Conzelman K. Calcium and the Regulation of Cytoskeletal Assembly, Structure and Contractility. 1986, 122: 232-249. PMID: 3792141, DOI: 10.1002/9780470513347.ch14.
- Reevaluation of the hydrophobic nature of the 110‐kD calmodulin‐, actin‐, and membrane‐binding protein of the intestinal microvillusConzelman K, Mooseker M. Reevaluation of the hydrophobic nature of the 110‐kD calmodulin‐, actin‐, and membrane‐binding protein of the intestinal microvillus. Journal Of Cellular Biochemistry 1986, 30: 271-279. PMID: 3700495, DOI: 10.1002/jcb.240300308.
- Cytochalasin B slows but does not prevent monomer addition at the barbed end of the actin filament.Bonder E, Mooseker M. Cytochalasin B slows but does not prevent monomer addition at the barbed end of the actin filament. Journal Of Cell Biology 1986, 102: 282-288. PMID: 3941155, PMCID: PMC2114038, DOI: 10.1083/jcb.102.1.282.
- Organization, Chemistry, and Assembly of the Cytoskeletal Apparatus of the Intestinal Brush BorderMooseker M. Organization, Chemistry, and Assembly of the Cytoskeletal Apparatus of the Intestinal Brush Border. Annual Review Of Cell And Developmental Biology 1985, 1: 209-241. PMID: 3916317, DOI: 10.1146/annurev.cb.01.110185.001233.
- Effects of actin filament cross-linking and filament length on actin-myosin interaction.Coleman T, Mooseker M. Effects of actin filament cross-linking and filament length on actin-myosin interaction. Journal Of Cell Biology 1985, 101: 1850-1857. PMID: 2932451, PMCID: PMC2113970, DOI: 10.1083/jcb.101.5.1850.
- Mechanisms of cytoskeletal regulation: modulation of membrane affinity in avian brush border and erythrocyte spectrins.Howe C, Sacramone L, Mooseker M, Morrow J. Mechanisms of cytoskeletal regulation: modulation of membrane affinity in avian brush border and erythrocyte spectrins. Journal Of Cell Biology 1985, 101: 1379-1385. PMID: 2931438, PMCID: PMC2113910, DOI: 10.1083/jcb.101.4.1379.
- Role of myosin in terminal web contraction in isolated intestinal epithelial brush borders.Keller T, Conzelman K, Chasan R, Mooseker M. Role of myosin in terminal web contraction in isolated intestinal epithelial brush borders. Journal Of Cell Biology 1985, 100: 1647-1655. PMID: 3988804, PMCID: PMC2113869, DOI: 10.1083/jcb.100.5.1647.
- Actin assembly and filament cross‐linking in the presence of TW 260/240, the tissue‐specific spectrin of the chicken intestinal brush borderFishkind D, Mooseker M, Bonder E. Actin assembly and filament cross‐linking in the presence of TW 260/240, the tissue‐specific spectrin of the chicken intestinal brush border. Cytoskeleton 1985, 5: 311-322. PMID: 4042144, DOI: 10.1002/cm.970050404.
- Calcium dependence of villin-induced actin depolymerization.Walsh T, Weber A, Davis K, Bonder E, Mooseker M. Calcium dependence of villin-induced actin depolymerization. Biochemistry 1984, 23: 6099-102. PMID: 6525347, DOI: 10.1021/bi00320a030.
- Brush border cytoskeleton and integration of cellular functions.Mooseker M, Bonder E, Conzelman K, Fishkind D, Howe C, Keller T. Brush border cytoskeleton and integration of cellular functions. Journal Of Cell Biology 1984, 99: 104s-112s. PMID: 6378918, PMCID: PMC2275581, DOI: 10.1083/jcb.99.1.104s.
- Effect of villin on the kinetics of actin polymerization.Walsh T, Higgins J, Weber A, Bonder E, Mooseker M. Effect of villin on the kinetics of actin polymerization. Biochemistry 1984, 23: 2613-21. PMID: 6432033, DOI: 10.1021/bi00307a012.
- Studies on the spectrin-like protein from the intestinal brush border, TW 260/240, and characterization of its interaction with the cytoskeleton and actin.Pearl M, Fishkind D, Mooseker M, Keene D, Keller T. Studies on the spectrin-like protein from the intestinal brush border, TW 260/240, and characterization of its interaction with the cytoskeleton and actin. Journal Of Cell Biology 1984, 98: 66-78. PMID: 6538573, PMCID: PMC2112984, DOI: 10.1083/jcb.98.1.66.
- The cytoskeletal apparatus of the intestinal brush border.Mooseker M, Bonder E, Conzelman K, Fishkind D, Howe C, Keller T. The cytoskeletal apparatus of the intestinal brush border. Kroc Foundation Series 1984, 17: 287-307. PMID: 6392486.
- Calcium-dependent regulation of cytoskeletal structure and contractility in the intestinal brush border.Mooseker M. Calcium-dependent regulation of cytoskeletal structure and contractility in the intestinal brush border. Progress In Clinical And Biological Research 1984, 168: 179-86. PMID: 6542665.
- Actin binding proteins of the brush borderMooseker M. Actin binding proteins of the brush border. Cell 1983, 35: 11-13. PMID: 6313218, DOI: 10.1016/0092-8674(83)90202-7.
- Characterization of the 110-kdalton actin-calmodulin-, and membrane-binding protein from microvilli of intestinal epithelial cells.Howe C, Mooseker M. Characterization of the 110-kdalton actin-calmodulin-, and membrane-binding protein from microvilli of intestinal epithelial cells. Journal Of Cell Biology 1983, 97: 974-985. PMID: 6311843, PMCID: PMC2112603, DOI: 10.1083/jcb.97.4.974.
- Direct measurement of critical concentrations and assembly rate constants at the two ends of an actin filamentBonder E, Fishkind D, Mooseker M. Direct measurement of critical concentrations and assembly rate constants at the two ends of an actin filament. Cell 1983, 34: 491-501. PMID: 6684506, DOI: 10.1016/0092-8674(83)90382-3.
- Actin from Thyone sperm assembles on only one end of an actin filament: a behavior regulated by profilin.Tilney L, Bonder E, Coluccio L, Mooseker M. Actin from Thyone sperm assembles on only one end of an actin filament: a behavior regulated by profilin. Journal Of Cell Biology 1983, 97: 112-124. PMID: 6863386, PMCID: PMC2112487, DOI: 10.1083/jcb.97.1.112.
- Mechanism of brush border contractility studied by the quick-freeze, deep-etch method.Hirokawa N, Keller T, Chasan R, Mooseker M. Mechanism of brush border contractility studied by the quick-freeze, deep-etch method. Journal Of Cell Biology 1983, 96: 1325-1336. PMID: 6601660, PMCID: PMC2112654, DOI: 10.1083/jcb.96.5.1325.
- Direct electron microscopic visualization of barbed end capping and filament cutting by intestinal microvillar 95-kdalton protein (villin): a new actin assembly assay using the limulus acrosomal processBonder E, Mooseker M. Direct electron microscopic visualization of barbed end capping and filament cutting by intestinal microvillar 95-kdalton protein (villin): a new actin assembly assay using the limulus acrosomal process. Journal Of Cell Biology 1983, 96: 1097-1107. PMID: 6682116, PMCID: PMC2112331, DOI: 10.1083/jcb.96.4.1097.
- Regulation of Cytoskeletal Structure and Contractility in the Brush BorderMooseker M, Keller T, Hirokawa N. Regulation of Cytoskeletal Structure and Contractility in the Brush Border. 1983, 95: 195-215. PMID: 6552204, DOI: 10.1002/9780470720769.ch12.
- Effects of villin on the polymerization and subunit exchange of actinWang Y, Bonder E, Mooseker M, Taylor D. Effects of villin on the polymerization and subunit exchange of actin. Cytoskeleton 1983, 3: 151-165. PMID: 6883468, DOI: 10.1002/cm.970030205.
- Ca++-calmodulin-dependent phosphorylation of myosin, and its role in brush border contraction in vitro.Keller T, Mooseker M. Ca++-calmodulin-dependent phosphorylation of myosin, and its role in brush border contraction in vitro. Journal Of Cell Biology 1982, 95: 943-959. PMID: 6897550, PMCID: PMC2112925, DOI: 10.1083/jcb.95.3.943.
- Analysis of cytoskeletal proteins and Ca2+-dependent regulation of structure in intestinal brush borders from rachitic chicksHowe C, Keller T, Mooseker M, Wasserman R. Analysis of cytoskeletal proteins and Ca2+-dependent regulation of structure in intestinal brush borders from rachitic chicks. Proceedings Of The National Academy Of Sciences Of The United States Of America 1982, 79: 1134-1138. PMID: 6951164, PMCID: PMC345915, DOI: 10.1073/pnas.79.4.1134.
- The Mechanism of Actin-Filament Assembly and Cross-LinkingPollard T, Aebi U, Cooper J, Elzinga M, Fowler W, Griffith L, Herman I, Heuser J, Isenberg G, Kiehart D, Levy J, MacLean-Fletcher S, Maupin P, Mooseker M, Runge M, Smith P, Tseng P. The Mechanism of Actin-Filament Assembly and Cross-Linking. 1982, 15-44. DOI: 10.1007/978-1-4684-4037-9_2.
- Chapter 8 The Brush Border of Intestinal Epithelium: A Model System for Analysis of Cell-Surface Architecture and MotilityMooseker M, Howe C. Chapter 8 The Brush Border of Intestinal Epithelium: A Model System for Analysis of Cell-Surface Architecture and Motility. 1982, 25: 143-174. PMID: 7109959, DOI: 10.1016/s0091-679x(08)61424-7.
- Regulation of contractility, cytoskeletal structure, and filament assembly in the brush border of intestinal epithelial cells.Mooseker M, Bonder E, Grimwade B, Howe C, Keller T, Wasserman R, Wharton K. Regulation of contractility, cytoskeletal structure, and filament assembly in the brush border of intestinal epithelial cells. Cold Spring Harbor Symposia On Quantitative Biology 1982, 46 Pt 2: 855-70. PMID: 6955109, DOI: 10.1101/sqb.1982.046.01.080.
- Regulation of microvillus structure: calcium-dependent solation and cross-linking of actin filaments in the microvilli of intestinal epithelial cells.Mooseker M, Graves T, Wharton K, Falco N, Howe C. Regulation of microvillus structure: calcium-dependent solation and cross-linking of actin filaments in the microvilli of intestinal epithelial cells. Journal Of Cell Biology 1980, 87: 809-822. PMID: 6893989, PMCID: PMC2110803, DOI: 10.1083/jcb.87.3.809.
- Brush-border alpha-actinin? Comparison of two proteins of the microvillus core with alpha-actinin by two-dimensional peptide mapping.Mooseker M, Stephens R. Brush-border alpha-actinin? Comparison of two proteins of the microvillus core with alpha-actinin by two-dimensional peptide mapping. Journal Of Cell Biology 1980, 86: 466-474. PMID: 7400215, PMCID: PMC2111479, DOI: 10.1083/jcb.86.2.466.
- Brush-border calmodulin. A major component of the isolated microvillus core.Howe C, Mooseker M, Graves T. Brush-border calmodulin. A major component of the isolated microvillus core. Journal Of Cell Biology 1980, 85: 916-923. PMID: 6893051, PMCID: PMC2111444, DOI: 10.1083/jcb.85.3.916.
- Brush border motility. Microvillar contraction in triton-treated brush borders isolated from intestinal epithelium.Mooseker M. Brush border motility. Microvillar contraction in triton-treated brush borders isolated from intestinal epithelium. Journal Of Cell Biology 1976, 71: 417-433. PMID: 11222, PMCID: PMC2109748, DOI: 10.1083/jcb.71.2.417.
- Actin filament-membrane attachment: are membrane particles involved?Tilney L, Mooseker M. Actin filament-membrane attachment: are membrane particles involved? Journal Of Cell Biology 1976, 71: 402-416. PMID: 1033184, PMCID: PMC2109749, DOI: 10.1083/jcb.71.2.402.
- Studies of muscle proteins in embryonic myocardial cells of cardiac lethal mutant mexican axolotls (Ambystoma mexicanum) by use of heavy meromyosin binding and sodium dodecyl sulfate polyacrylamide gel electrophoresis.Lemanski L, Mooseker M, Peachey L, Iyengar M. Studies of muscle proteins in embryonic myocardial cells of cardiac lethal mutant mexican axolotls (Ambystoma mexicanum) by use of heavy meromyosin binding and sodium dodecyl sulfate polyacrylamide gel electrophoresis. Journal Of Cell Biology 1976, 68: 375-388. PMID: 1107335, PMCID: PMC2109630, DOI: 10.1083/jcb.68.2.375.
- Organization of an actin filament-membrane complex. Filament polarity and membrane attachment in the microvilli of intestinal epithelial cells.Mooseker M, Tilney L. Organization of an actin filament-membrane complex. Filament polarity and membrane attachment in the microvilli of intestinal epithelial cells. Journal Of Cell Biology 1975, 67: 725-743. PMID: 1202021, PMCID: PMC2111646, DOI: 10.1083/jcb.67.3.725.
- MICROTUBULES: EVIDENCE FOR 13 PROTOFILAMENTSTilney L, Bryan J, Bush D, Fujiwara K, Mooseker M, Murphy D, Snyder D. MICROTUBULES: EVIDENCE FOR 13 PROTOFILAMENTS. Journal Of Cell Biology 1973, 59: 267-275. PMID: 4805001, PMCID: PMC2109099, DOI: 10.1083/jcb.59.2.267.
- THE POLYMERIZATION OF ACTIN: ITS ROLE IN THE GENERATION OF THE ACROSOMAL PROCESS OF CERTAIN ECHINODERM SPERMTilney L, Hatano S, Ishikawa H, Mooseker M. THE POLYMERIZATION OF ACTIN: ITS ROLE IN THE GENERATION OF THE ACROSOMAL PROCESS OF CERTAIN ECHINODERM SPERM. Journal Of Cell Biology 1973, 59: 109-126. PMID: 4356568, PMCID: PMC2110911, DOI: 10.1083/jcb.59.1.109.
- ISOLATION AND REACTIVATION OF THE AXOSTYLEMooseker M, Tilney L. ISOLATION AND REACTIVATION OF THE AXOSTYLE. Journal Of Cell Biology 1973, 56: 13-26. PMID: 4345162, PMCID: PMC2108841, DOI: 10.1083/jcb.56.1.13.
- Actin in the Brush-Border of Epithelial Cells of the Chicken IntestineTilney L, Mooseker M. Actin in the Brush-Border of Epithelial Cells of the Chicken Intestine. Proceedings Of The National Academy Of Sciences Of The United States Of America 1971, 68: 2611-2615. PMID: 4944636, PMCID: PMC389479, DOI: 10.1073/pnas.68.10.2611.