Marie-Louise Landry, MD
Professor of Laboratory Medicine and of Medicine (Infectious Diseases); Director, Clinical Virology Laboratory; Vice Chair, Laboratory Medicine
Research & Publications
Biography
News
Research Summary
My interests focus on the rapid detection and quantitation of viruses for clinical diagnosis and the impact of new test methods on patient management. Ongoing projects include optimization of rapid assays for respiratory viruses including SARS CoV-2 and development of real-time molecular methods for viral diagnosis.
Coauthors
Research Interests
Prognosis; Respiratory Tract Diseases; Virus Diseases; Diagnostic Techniques and Procedures
Selected Publications
- High Agreement Between an Ultrasensitive Clostridioides difficile Toxin Assay and a C. difficile Laboratory Algorithm Utilizing GDH-and-Toxin Enzyme Immunoassays and Cytotoxin Testing.Landry ML, Topal JE, Estis J, Katzenbach P, Nolan N, Sandlund J. High Agreement Between an Ultrasensitive Clostridioides difficile Toxin Assay and a C. difficile Laboratory Algorithm Utilizing GDH-and-Toxin Enzyme Immunoassays and Cytotoxin Testing. Journal Of Clinical Microbiology 2020, 58.
- Coast-to-Coast Spread of SARS-CoV-2 during the Early Epidemic in the United States.Fauver JR, Petrone ME, Hodcroft EB, Shioda K, Ehrlich HY, Watts AG, Vogels CBF, Brito AF, Alpert T, Muyombwe A, Razeq J, Downing R, Cheemarla NR, Wyllie AL, Kalinich CC, Ott IM, Quick J, Loman NJ, Neugebauer KM, Greninger AL, Jerome KR, Roychoudhury P, Xie H, Shrestha L, Huang ML, Pitzer VE, Iwasaki A, Omer SB, Khan K, Bogoch II, Martinello RA, Foxman EF, Landry ML, Neher RA, Ko AI, Grubaugh ND. Coast-to-Coast Spread of SARS-CoV-2 during the Early Epidemic in the United States. Cell 2020, 181:990-996.e5.
- Hepatitis B and D viruses.Tang YW, Horvat RT, Landry ML. Hepatitis B and D viruses. In Manual of Clinical Microbiology, 12th Edition, American Society of Microbiology, Washington DC.
- Manual of Clinical Microbiology, 12th EditionPfaller MA, Carroll KC, Funke G, Landry ML, Richter SS, Warnock D, Eds., American Society of Microbiology, Washington DC.
- Algorithms for detection and identification of viruses.Landry ML, Caliendo A, Ginocchio C, Hayden, R, Tang YW. In Manual of Clinical Microbiology, 12th Edition, American Society of Microbiology, Washington DC.
- Rhinoviruses.Lu XY, Landry ML. In Manual of Clinical Microbiology, 12th Edition, American Society of Microbiology, Washington DC
- Viral encephalitis.Landry ML. Current Diagnosis and Treatment- Infectious Diseases. McGraw-Hill Medical
- Improving laboratory test utilisation at the multihospital Yale New Haven Health System.Harb R, Hajdasz D, Landry ML, Sussman LS. Improving laboratory test utilisation at the multihospital Yale New Haven Health System. BMJ Open Quality 2019, 8:e000689.
- Markers of CNS Injury in Adults Living With HIV With CSF HIV Not Detected vs Detected <20 Copies/mL.Farhadian SF, Mistry H, Kirchwey T, Chiarella J, Calvi R, Chintanaphol M, Patel P, Landry ML, Robertson K, Spudich SS. Markers of CNS Injury in Adults Living With HIV With CSF HIV Not Detected vs Detected <20 Copies/mL. Open Forum Infectious Diseases 2019, 6:ofz528.
- Rapid microbial antigen tests.Campbell S and Landry, ML. In Advanced Techniques in Diagnostic Microbiology, 3rd edition, Springer International Publishing Company.
- Antiviral Response in the Nasopharynx Identifies Patients With Respiratory Virus Infection.Landry ML, Foxman EF. Antiviral Response in the Nasopharynx Identifies Patients With Respiratory Virus Infection. The Journal Of Infectious Diseases 2018, 217:897-905.
- Adenovirus Type 4 Respiratory Infections among Civilian Adults, Northeastern United States, 2011-20151.Kajon AE, Lamson DM, Bair CR, Lu X, Landry ML, Menegus M, Erdman DD, St George K. Adenovirus Type 4 Respiratory Infections among Civilian Adults, Northeastern United States, 2011-20151. Emerging Infectious Diseases 2018, 24:201-209.
- Detection of Influenza A and B Viruses and Respiratory Syncytial Virus by Use of Clinical Laboratory Improvement Amendments of 1988 (CLIA)-Waived Point-of-Care Assays: a Paradigm Shift to Molecular Tests.Azar MM, Landry ML. Detection of Influenza A and B Viruses and Respiratory Syncytial Virus by Use of Clinical Laboratory Improvement Amendments of 1988 (CLIA)-Waived Point-of-Care Assays: a Paradigm Shift to Molecular Tests. Journal Of Clinical Microbiology 2018, 56.
- Laboratory Diagnosis of Zika Virus Infection.Landry ML, St George K. Laboratory Diagnosis of Zika Virus Infection. Archives Of Pathology & Laboratory Medicine 2017, 141:60-67.
- Primary isolation of viruses.Landry, M.L. and Leland D. In Clinical Virology Manual, Hodinka R, Young S Leffelholz M. (Eds), 5th edition, American Society for Microbiology Press, Washington, D.C.
- Immunologic and Molecular Assays for Viral Diagnosis,Landry ML and Tang YW. Immunologic and Molecular Assays for Viral Diagnosis, in Manual of Molecular and Clinical Laboratory Immunology 8th edition, 2016.
- Primary isolation of viruses.Landry, M.L. and Leland D. In Clinical Virology Manual, Hodinka R, Young S Leffelholz M. (Eds), 5th edition, American Society for Microbiology Press, Washington, D.C.
- Immunologic and Molecular Assays for Viral DiagnosisLandry ML and Tang YW. In Manual of Molecular and Clinical Laboratory Immunology 8th edition, American Society for Microbiology Press, Washington, D.C.
- Zika Virus: From Obscurity to Potentially Devastating International Threat.Landry ML, Ko AI, Kramer LD, Vasilakis N. Zika Virus: From Obscurity to Potentially Devastating International Threat. Clinical Chemistry 2016, 62:1175-80.
- Sensitive Detection and Simultaneous Discrimination of Influenza A and B Viruses in Nasopharyngeal Swabs in a Single Assay Using Next-Generation Sequencing-Based Diagnostics.Zhao J, Liu J, Vemula SV, Lin C, Tan J, Ragupathy V, Wang X, Mbondji-Wonje C, Ye Z, Landry ML, Hewlett I. Sensitive Detection and Simultaneous Discrimination of Influenza A and B Viruses in Nasopharyngeal Swabs in a Single Assay Using Next-Generation Sequencing-Based Diagnostics. PloS One 2016, 11:e0163175.
- Parvovirus B19.Landry ML. Parvovirus B19. Microbiology Spectrum 2016, 4.
- Immunoglobulin M for Acute Infection: True or False?Landry ML. Immunoglobulin M for Acute Infection: True or False? Clinical And Vaccine Immunology : CVI 2016, 23:540-5.
- Nanomicroarray and multiplex next-generation sequencing for simultaneous identification and characterization of influenza viruses.Zhao J, Ragupathy V, Liu J, Wang X, Vemula SV, El Mubarak HS, Ye Z, Landry ML, Hewlett I. Nanomicroarray and multiplex next-generation sequencing for simultaneous identification and characterization of influenza viruses. Emerging Infectious Diseases 2015, 21:400-8.
- Rapid diagnosis of influenza: state of the art.Peaper DR, Landry ML. Rapid diagnosis of influenza: state of the art. Clinics In Laboratory Medicine 2014, 34:365-85.
- Comparison of Simplexa Flu A/B & RSV PCR with cytospin-immunofluorescence and laboratory-developed TaqMan PCR in predominantly adult hospitalized patients.Landry ML, Ferguson D. Comparison of Simplexa Flu A/B & RSV PCR with cytospin-immunofluorescence and laboratory-developed TaqMan PCR in predominantly adult hospitalized patients. Journal Of Clinical Microbiology 2014, 52:3057-9.
- Laboratory diagnosis of viral infection.Peaper DR, Landry ML. Laboratory diagnosis of viral infection. Handbook Of Clinical Neurology 2014, 123:123-47.
- Comparison of Simplexa universal direct PCR with cytotoxicity assay for diagnosis of Clostridium difficile infection: performance, cost, and correlation with disease.Landry ML, Ferguson D, Topal J. Comparison of Simplexa universal direct PCR with cytotoxicity assay for diagnosis of Clostridium difficile infection: performance, cost, and correlation with disease. Journal Of Clinical Microbiology 2014, 52:275-80.
- A highly sensitive europium nanoparticle-based immunoassay for detection of influenza A/B virus antigen in clinical specimens.Zhang P, Vemula SV, Zhao J, Du B, Mohan H, Liu J, El Mubarak HS, Landry ML, Hewlett I. A highly sensitive europium nanoparticle-based immunoassay for detection of influenza A/B virus antigen in clinical specimens. Journal Of Clinical Microbiology 2014, 52:4385-7.
Clinical Trials
Conditions | Study Title |
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Diseases of the Respiratory Systems; COVID-19 Inpatient; COVID-19 Outpatient | A Study Tracking Health Care Workers Exposed to COVID-19 |