Marc C Llaguno, PhD

• Chenxiang Lin
• Elizabeth Jonas
• Frederic Pincet
• Frederick Sigworth
• Nelli Mnatsakanyan
• Youshan Yang

Cryoelectron Microscopy

• Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex.Mnatsakanyan N, Park HA, Wu J, He X, Llaguno MC, Latta M, Miranda P, Murtishi B, Graham M, Weber J, Levy RJ, Pavlov EV, Jonas EA. Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex. Cell Death And Differentiation 2022 PMID: 35322203, DOI: 10.1038/s41418-022-00972-7.
• A mitochondrial megachannel resides in monomeric F1FO ATP synthase.Mnatsakanyan N, Llaguno MC, Yang Y, Yan Y, Weber J, Sigworth FJ, Jonas EA. A mitochondrial megachannel resides in monomeric F1FO ATP synthase. Nature Communications 2019, 10: 5823. PMID: 31862883, PMCID: PMC6925261, DOI: 10.1038/s41467-019-13766-2.
• Placing and shaping liposomes with reconfigurable DNA nanocages.Zhang Z, Yang Y, Pincet F, C Llaguno M, Lin C. Placing and shaping liposomes with reconfigurable DNA nanocages. Nature Chemistry 2017, 9: 653-659. PMID: 28644472, PMCID: PMC5542812, DOI: 10.1038/nchem.2802.
• bSUM: A bead-supported unilamellar membrane system facilitating unidirectional insertion of membrane proteins into giant vesicles.Zheng H, Lee S, Llaguno MC, Jiang QX. bSUM: A bead-supported unilamellar membrane system facilitating unidirectional insertion of membrane proteins into giant vesicles. The Journal Of General Physiology 2016, 147: 77-93. PMID: 26712851, PMCID: PMC4692488, DOI: 10.1085/jgp.201511448.
• Chemically functionalized carbon films for single molecule imaging.Llaguno MC, Xu H, Shi L, Huang N, Zhang H, Liu Q, Jiang QX. Chemically functionalized carbon films for single molecule imaging. Journal Of Structural Biology 2014, 185: 405-17. PMID: 24457027, PMCID: PMC3990355, DOI: 10.1016/j.jsb.2014.01.006.
• Phase transitions in the assembly of multivalent signalling proteins.Li P, Banjade S, Cheng HC, Kim S, Chen B, Guo L, Llaguno M, Hollingsworth JV, King DS, Banani SF, Russo PS, Jiang QX, Nixon BT, Rosen MK. Phase transitions in the assembly of multivalent signalling proteins. Nature 2012, 483: 336-40. PMID: 22398450, PMCID: PMC3343696, DOI: 10.1038/nature10879.
• Massive calcium-activated endocytosis without involvement of classical endocytic proteins.Lariccia V, Fine M, Magi S, Lin MJ, Yaradanakul A, Llaguno MC, Hilgemann DW. Massive calcium-activated endocytosis without involvement of classical endocytic proteins. The Journal Of General Physiology 2011, 137: 111-32. PMID: 21187336, PMCID: PMC3010057, DOI: 10.1085/jgp.201010468.
• Massive endocytosis driven by lipidic forces originating in the outer plasmalemmal monolayer: a new approach to membrane recycling and lipid domains.Fine M, Llaguno MC, Lariccia V, Lin MJ, Yaradanakul A, Hilgemann DW. Massive endocytosis driven by lipidic forces originating in the outer plasmalemmal monolayer: a new approach to membrane recycling and lipid domains. The Journal Of General Physiology 2011, 137: 137-54. PMID: 21242300, PMCID: PMC3032378, DOI: 10.1085/jgp.201010469.