Lohith Gowda, MD, MRCP
Assistant Professor; Assistant Professor of Medicine (Hematology), Internal Medicine
Research & Publications
Biography
Extensive Research Description
Targeted therapy; Transfusion associated immunomodulation
Coauthors
Research Interests
Blood Transfusion; Bone Marrow Diseases; Immunotherapy; Leukemia; Lymphoma; Multiple Myeloma; Hematopoietic Stem Cell Transplantation
Selected Publications
- CAR-T cell manufacture: snatching victory when defeat is looming.Gowda L, Shah NC. CAR-T cell manufacture: snatching victory when defeat is looming. Transfusion 2018, 58:1335-1337.
- Primary plasma cell leukemia: autologous stem cell transplant in an era of novel induction drugs.Gowda L, Shah M, Badar I, Bashir Q, Shah N, Patel K, Kanagal-Shamanna R, Mehta R, Weber DM, Lee HC, Manasanch EE, Shah A, Thomas SK, Parmar S, Nieto Y, Orlowski RZ, Champlin R, Qazilbash MH. Primary plasma cell leukemia: autologous stem cell transplant in an era of novel induction drugs. Bone Marrow Transplantation 2019, 54:1089-1093.
- Hepatosplenic T-Cell Lymphomas.Gowda L, Foss F. Hepatosplenic T-Cell Lymphomas. Cancer Treatment And Research 2019, 176:185-193.
- A dual strategy to optimize hematopoietic progenitor cell collections: validation of a simple prediction algorithm and use of collect flow rates guided by mononuclear cell count.Godbey EA, Dormesy S, Gowda L, Nandi V, Paradiso S, Sachais BS, Shi PA. A dual strategy to optimize hematopoietic progenitor cell collections: validation of a simple prediction algorithm and use of collect flow rates guided by mononuclear cell count. Transfusion 2019, 59:659-670.
- HLA-DP mismatch and CMV reactivation increase risk of aGVHD independently in recipients of allogeneic stem cell transplant.Ghobadi A, Milton DR, Gowda L, Rondon G, Chemaly RF, Hamdi A, Alousi A, Afrough A, Oran B, Ciurea S, Kebriaei P, Popat UR, Qazilbash MH, Shpall EJ, Champlin RE, Bashir Q. HLA-DP mismatch and CMV reactivation increase risk of aGVHD independently in recipients of allogeneic stem cell transplant. Current Research In Translational Medicine 2019, 67:51-55.
- The impact of a multimodal approach to vancomycin discontinuation in hematopoietic stem cell transplant recipients (HSCT) with febrile neutropenia (FN).Perreault S, McManus D, Bar N, Foss F, Gowda L, Isufi I, Seropian S, Malinis M, Topal JE. The impact of a multimodal approach to vancomycin discontinuation in hematopoietic stem cell transplant recipients (HSCT) with febrile neutropenia (FN). Transplant Infectious Disease : An Official Journal Of The Transplantation Society 2019, 21:e13059.
- Allogeneic stem cell transplantation and combination antiretroviral therapy: cautions, complications, and considerations.Shallis RM, Gleeson S, Azar M, Malinis M, Xu ML, Seropian SE, Gowda L, Zeidan AM. Allogeneic stem cell transplantation and combination antiretroviral therapy: cautions, complications, and considerations. Leukemia & Lymphoma 2019, 60:2584-2587.
- How we handled the dextran shortage: an alternative washing or dilution solution for cord blood infusions.Reich-Slotky R, Bachegowda LS, Ancharski M, Mendeleyeva L, Rubinstein P, Rennert H, Shore T, van Besien K, Cushing M. How we handled the dextran shortage: an alternative washing or dilution solution for cord blood infusions. Transfusion 2015, 55:1147-53.
- Engraftment for CD34 selected stem cell products is not compromised by cryopreservation.Reich-Slotky R, Bachegowda LS, Ancharski M, Gergis U, van Besien K, Cushing MM. Engraftment for CD34 selected stem cell products is not compromised by cryopreservation. Transfusion 2016, 56:893-8.
- Pexmetinib: A Novel Dual Inhibitor of Tie2 and p38 MAPK with Efficacy in Preclinical Models of Myelodysplastic Syndromes and Acute Myeloid Leukemia.Bachegowda L, Morrone K, Winski SL, Mantzaris I, Bartenstein M, Ramachandra N, Giricz O, Sukrithan V, Nwankwo G, Shahnaz S, Bhagat T, Bhattacharyya S, Assal A, Shastri A, Gordon-Mitchell S, Pellagatti A, Boultwood J, Schinke C, Yu Y, Guha C, Rizzi J, Garrus J, Brown S, Wollenberg L, Hogeland G, Wright D, Munson M, Rodriguez M, Gross S, Chantry D, Zou Y, Platanias L, Burgess LE, Pradhan K, Steidl U, Verma A. Pexmetinib: A Novel Dual Inhibitor of Tie2 and p38 MAPK with Efficacy in Preclinical Models of Myelodysplastic Syndromes and Acute Myeloid Leukemia. Cancer Research 2016, 76:4841-4849.
- Survey on Transfusion-Transmitted Cytomegalovirus and Cytomegalovirus Disease Mitigation.Weisberg SP, Staley EM, Williams LA, Pham HP, Bachegowda LS, Cheng YH, Schwartz J, Shaz BH. Survey on Transfusion-Transmitted Cytomegalovirus and Cytomegalovirus Disease Mitigation. Archives Of Pathology & Laboratory Medicine 2017, 141:1705-1711.
- Sensitive PCR-based monitoring and early detection of relapsed JAK2 V617F myelofibrosis following transplantation.Shah MV, Patel KP, Luthra R, Kanagal-Shamanna R, Mehrotra M, Bachegowda LS, Champlin RE, Verstovsek S, Popat UR. Sensitive PCR-based monitoring and early detection of relapsed JAK2 V617F myelofibrosis following transplantation. British Journal Of Haematology 2018, 183:831-835.
- Intracranial tumor lysis and cerebral edema after administration of intrathecal methotrexate: a case report and discussion.Bachegowda LS, Grivas PD, Anand R, Stecker E, Ward K. Intracranial tumor lysis and cerebral edema after administration of intrathecal methotrexate: a case report and discussion. Medical Oncology (Northwood, London, England) 2010, 27:1079-81.
- Granuloma annulare.Gupta D, Hess B, Bachegowda L. Granuloma annulare. TheScientificWorldJournal 2010, 10:384-6.
- Role of plasmapheresis in the management of myeloma kidney: a systematic review.Gupta D, Bachegowda L, Phadke G, Boren S, Johnson D, Misra M. Role of plasmapheresis in the management of myeloma kidney: a systematic review. Hemodialysis International. International Symposium On Home Hemodialysis 2010, 14:355-63.
- Changes in intern attitudes toward medical error and disclosure.Varjavand N, Bachegowda LS, Gracely E, Novack DH. Changes in intern attitudes toward medical error and disclosure. Medical Education 2012, 46:668-77.
- Signal transduction inhibitors in treatment of myelodysplastic syndromes.Bachegowda L, Gligich O, Mantzaris I, Schinke C, Wyville D, Carrillo T, Braunschweig I, Steidl U, Verma A. Signal transduction inhibitors in treatment of myelodysplastic syndromes. Journal Of Hematology & Oncology 2013, 6:50.
- Taxanes: impact on breast cancer therapy.Bachegowda LS, Makower DF, Sparano JA. Taxanes: impact on breast cancer therapy. Anti-cancer Drugs 2014, 25:512-21.
- Genetic and molecular targets in lymphoma: implications for prognosis and treatment.Bachegowda LS, Barta SK. Genetic and molecular targets in lymphoma: implications for prognosis and treatment. Future Oncology (London, England) 2014, 10:2509-28.
- Impact of Uniform Methods on Interlaboratory Antibody Titration Variability: Antibody Titration and Uniform Methods.Bachegowda LS, Cheng YH, Long T, Shaz BH. Impact of Uniform Methods on Interlaboratory Antibody Titration Variability: Antibody Titration and Uniform Methods. Archives Of Pathology & Laboratory Medicine 2017, 141:131-138.
- Predictive model for survival in patients with AML/MDS receiving haploidentical stem cell transplantation.Bachegowda LS, Saliba RM, Ramlal R, Kongtim P, Chen J, Rondon G, Wallis W, Alousi A, Ahmed S, Hosing CM, Parmar S, Qazilbash M, Khouri IF, Bashir Q, Oran B, Popat U, Shpall EJ, Marin D, Rezvani K, Kebriaei P, Champlin RE, Ciurea SO. Predictive model for survival in patients with AML/MDS receiving haploidentical stem cell transplantation. Blood 2017, 129:3031-3033.
- Impact of predictive scoring model and e-mail messages on African American blood donors.Bachegowda LS, Timm B, Dasgupta P, Hillyer CD, Kessler D, Rebosa M, France CR, Shaz BH. Impact of predictive scoring model and e-mail messages on African American blood donors. Transfusion 2017, 57:1515-1521.
- Investigation of increased platelet alloimmunization screening in the era of pathogen-reduced platelets treated with psoralen/UV light.Hendrickson JE, Mendoza H, Ross R, Siddon AJ, Gowda L, Hauser RG, Schulz WL, Tormey CA. Investigation of increased platelet alloimmunization screening in the era of pathogen-reduced platelets treated with psoralen/UV light. Transfusion 2020, 60:650-651.
- Cui bono? Finding the value of allogeneic stem cell transplantation for lower-risk myelodysplastic syndromes.Shallis RM, Podoltsev NA, Gowda L, Zeidan AM, Gore SD. Cui bono? Finding the value of allogeneic stem cell transplantation for lower-risk myelodysplastic syndromes. Expert Review Of Hematology 2020, 13:447-460.
- Isolated trisomy 11 in patients with acute myeloid leukemia - is the prognosis not as grim as previously thought?Bewersdorf JP, Shallis RM, Diadamo A, Gowda L, Podoltsev NA, Siddon A, Zeidan AM. Isolated trisomy 11 in patients with acute myeloid leukemia - is the prognosis not as grim as previously thought? Leukemia & Lymphoma 2020, 61:2254-2257.
- Clinical outcomes and characteristics of patients with TP53-mutated acute myeloid leukemia or myelodysplastic syndromes: a single center experience.Bewersdorf JP, Shallis RM, Gowda L, Wei W, Hager K, Isufi I, Kim TK, Pillai MM, Seropian S, Podoltsev NA, Gore SD, Siddon AJ, Zeidan AM. Clinical outcomes and characteristics of patients with TP53-mutated acute myeloid leukemia or myelodysplastic syndromes: a single center experience. Leukemia & Lymphoma 2020, 61:2180-2190.
- Outcomes for allogeneic stem cell transplantation in refractory mycosis fungoides and primary cutaneous gamma Delta T cell lymphomas.Isufi I, Seropian S, Gowda L, Wilson LD, Roberts K, Girardi M, Perreault S, Foss F. Outcomes for allogeneic stem cell transplantation in refractory mycosis fungoides and primary cutaneous gamma Delta T cell lymphomas. Leukemia & Lymphoma 2020, 61:2955-2961.
- Attenuated Novel SARS Coronavirus 2 Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient on Ruxolitinib.Foss FM, Rubinowitz A, Landry ML, Isufi I, Gowda L, Seropian S, Perreault S, Shenoi SV. Attenuated Novel SARS Coronavirus 2 Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient on Ruxolitinib. Clinical Lymphoma, Myeloma & Leukemia 2020, 20:720-723.
- A case of acute myeloid leukemia with unusual germline CEBPA mutation: lessons learned about mutation detection, location, and penetrance.Mendoza H, Chen PH, Pine AB, Siddon AJ, Bale AE, Gowda L, Killie A, Richards J, Varin-Tremblay C, Kloss R, Podoltsev NA. A case of acute myeloid leukemia with unusual germline CEBPA mutation: lessons learned about mutation detection, location, and penetrance. Leukemia & Lymphoma 2020, 1-4.