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Lieping Chen, MD, PhD

United Technologies Corporation Professor in Cancer Research and Professor of Immunobiology, of Dermatology and of Medicine (Medical Oncology); Co-Leader, Cancer Immunology, Yale Cancer Center

Research Summary

T lymphocyte biology and functional modification

Specialized Terms: Lymphocyte activation and tolerance; costimulation and coinhibition; tumor microenvironment; cancer immunotherapy

Extensive Research Description

My laboratory is interested in:

  1. Molecular regulation of T cell quiescence, activation, tolerance and memory
  2. Mechanisms of tumor escape from immune attack in the tumor microenvironment
  3. Developing novel treatments for human diseases based on our laboratory discoveries


Research Interests

Immunotherapy; Inflammation; Medical Oncology; Neoplasms; Autoimmunity

Public Health Interests

Cancer; Immunology

Selected Publications