Kishu Ranjan, PhD
Associate Research Scientist in Pathology
Research & Publications
Biography
Coauthors
Selected Publications
- Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein responseRanjan K, Hedl M, Sinha S, Zhang X, Abraham C. Ubiquitination of ATF6 by disease-associated RNF186 promotes the innate receptor-induced unfolded protein response. Journal Of Clinical Investigation 2021, 131: e145472. PMID: 34623328, PMCID: PMC8409591, DOI: 10.1172/jci145472.
- The E3 ubiquitin ligase RNF186 and RNF186 risk variants regulate innate receptor-induced outcomesRanjan K, Hedl M, Abraham C. The E3 ubiquitin ligase RNF186 and RNF186 risk variants regulate innate receptor-induced outcomes. Proceedings Of The National Academy Of Sciences Of The United States Of America 2021, 118: e2013500118. PMID: 34353900, PMCID: PMC8364215, DOI: 10.1073/pnas.2013500118.
- Myeloid Cell Expression of LACC1 Is Required for Bacterial Clearance and Control of Intestinal InflammationKang JW, Yan J, Ranjan K, Zhang X, Turner JR, Abraham C. Myeloid Cell Expression of LACC1 Is Required for Bacterial Clearance and Control of Intestinal Inflammation. Gastroenterology 2020, 159: 1051-1067. PMID: 32693188, PMCID: PMC8139320, DOI: 10.1053/j.gastro.2020.07.024.
- Insights of Endocytosis Signaling in Health and DiseasePathak C, Vaidya F, Waghela B, Jaiswara P, Gupta V, Kumar A, Rajendran B, Ranjan K. Insights of Endocytosis Signaling in Health and Disease. International Journal Of Molecular Sciences 2023, 24: 2971. PMID: 36769293, PMCID: PMC9918140, DOI: 10.3390/ijms24032971.
- LACC1 Required for NOD2-Induced, ER Stress-Mediated Innate Immune Outcomes in Human Macrophages and LACC1 Risk Variants Modulate These OutcomesHuang C, Hedl M, Ranjan K, Abraham C. LACC1 Required for NOD2-Induced, ER Stress-Mediated Innate Immune Outcomes in Human Macrophages and LACC1 Risk Variants Modulate These Outcomes. Cell Reports 2019, 29: 4525-4539.e4. PMID: 31875558, PMCID: PMC7372507, DOI: 10.1016/j.celrep.2019.11.105.
- FADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosisRanjan K, Pathak C. FADD regulates NF-κB activation and promotes ubiquitination of cFLIPL to induce apoptosis. Scientific Reports 2016, 6: 22787. PMID: 26972597, PMCID: PMC4789601, DOI: 10.1038/srep22787.
- Implications of Toll-like receptors (TLRs) and their signaling mechanisms in human cancersChandrasekar S, Palaniyandi T, Parthasarathy U, Surendran H, Viswanathan S, Wahab M, Baskar G, Natarajan S, Ranjan K. Implications of Toll-like receptors (TLRs) and their signaling mechanisms in human cancers. Pathology - Research And Practice 2023, 248: 154673. PMID: 37453359, DOI: 10.1016/j.prp.2023.154673.
- Role of HLA class-I antigen peptide loading complex components in immune evasion and treatment sensitivity in human lung cancer.Costantini A, Ranjan K, Ferrone S, Schalper K. Role of HLA class-I antigen peptide loading complex components in immune evasion and treatment sensitivity in human lung cancer. Journal Of Clinical Oncology 2023, 41: 2623-2623. DOI: 10.1200/jco.2023.41.16_suppl.2623.
- Abstract 6762: Tumor immune microenvironment &genomic features of non-small cell lung carcinomas in patients with HIV (PWH)Desai S, Ranjan K, Salahuddin S, Yusuf R, Gu J, Tang D, Kong Y, Rajendran B, Zhao H, Kluger Y, Goldberg S, Emu B, Schalper K. Abstract 6762: Tumor immune microenvironment &genomic features of non-small cell lung carcinomas in patients with HIV (PWH). Cancer Research 2023, 83: 6762-6762. DOI: 10.1158/1538-7445.am2023-6762.
- 148 TAP2 deficiency mediates adaptive immune evasion and immunotherapy resistance in human non-small cell lung cancerRanjan K, Deen I, Rodas M, Gianino N, Ferrone S, Schalper K. 148 TAP2 deficiency mediates adaptive immune evasion and immunotherapy resistance in human non-small cell lung cancer. 2022, a161-a161. DOI: 10.1136/jitc-2022-sitc2022.0148.
- SARS-CoV-2 Variants: Impact of Spike Mutations on Vaccine and Therapeutic StrategiesRaman R, Patel K, Ranjan K. SARS-CoV-2 Variants: Impact of Spike Mutations on Vaccine and Therapeutic Strategies. 2022, 143-160. DOI: 10.1007/978-3-031-08045-6_7.
- Higher BCG‐induced trained immunity prevalence predicts protection from COVID‐19: Implications for ongoing BCG trialsSingh S, Kishore D, Singh R, Pathak C, Ranjan K. Higher BCG‐induced trained immunity prevalence predicts protection from COVID‐19: Implications for ongoing BCG trials. Clinical And Translational Discovery 2022, 2: e60. PMID: 35938058, PMCID: PMC9347530, DOI: 10.1002/ctd2.60.
- Advanced Glycation End Products-Mediated Oxidative Stress and Regulated Cell Death Signaling in CancerPathak C, Vaidya F, Waghela B, Chhipa A, Tiwari B, Ranjan K. Advanced Glycation End Products-Mediated Oxidative Stress and Regulated Cell Death Signaling in Cancer. 2022, 535-550. DOI: 10.1007/978-981-15-9411-3_44.
- COVID-19: Unmasking Emerging SARS-CoV-2 Variants, Vaccines and Therapeutic StrategiesRaman R, Patel KJ, Ranjan K. COVID-19: Unmasking Emerging SARS-CoV-2 Variants, Vaccines and Therapeutic Strategies. Biomolecules 2021, 11: 993. PMID: 34356617, PMCID: PMC8301790, DOI: 10.3390/biom11070993.
- AGE-RAGE synergy influences programmed cell death signaling to promote cancerWaghela BN, Vaidya FU, Ranjan K, Chhipa AS, Tiwari BS, Pathak C. AGE-RAGE synergy influences programmed cell death signaling to promote cancer. Molecular And Cellular Biochemistry 2020, 476: 585-598. PMID: 33025314, DOI: 10.1007/s11010-020-03928-y.
- Cell-Penetrable Peptide-Conjugated FADD Induces Apoptosis and Regulates Inflammatory Signaling in Cancer CellsRanjan K, Waghela BN, Vaidya FU, Pathak C. Cell-Penetrable Peptide-Conjugated FADD Induces Apoptosis and Regulates Inflammatory Signaling in Cancer Cells. International Journal Of Molecular Sciences 2020, 21: 6890. PMID: 32961826, PMCID: PMC7555701, DOI: 10.3390/ijms21186890.
- Intestinal Immune Homeostasis and Inflammatory Bowel Disease: A Perspective on Intracellular Response MechanismsRanjan K. Intestinal Immune Homeostasis and Inflammatory Bowel Disease: A Perspective on Intracellular Response Mechanisms. Gastrointestinal Disorders 2020, 2: 24. DOI: 10.3390/gidisord2030024.
- Hydrophilic Acylated Surface Protein A (HASPA) of Leishmania donovani: Expression, Purification and Biophysico-Chemical CharacterizationKumar M, Ranjan K, Singh V, Pathak C, Pappachan A, Singh DD. Hydrophilic Acylated Surface Protein A (HASPA) of Leishmania donovani: Expression, Purification and Biophysico-Chemical Characterization. The Protein Journal 2017, 36: 343-351. PMID: 28634775, DOI: 10.1007/s10930-017-9726-x.
- Expression of FADD and cFLIPL balances mitochondrial integrity and redox signaling to substantiate apoptotic cell deathRanjan K, Pathak C. Expression of FADD and cFLIPL balances mitochondrial integrity and redox signaling to substantiate apoptotic cell death. Molecular And Cellular Biochemistry 2016, 422: 135-150. PMID: 27619661, DOI: 10.1007/s11010-016-2813-z.
- Expression of cFLIPL Determines the Basal Interaction of Bcl‐2 With Beclin‐1 and Regulates p53 Dependent Ubiquitination of Beclin‐1 During Autophagic StressRanjan K, Pathak C. Expression of cFLIPL Determines the Basal Interaction of Bcl‐2 With Beclin‐1 and Regulates p53 Dependent Ubiquitination of Beclin‐1 During Autophagic Stress. Journal Of Cellular Biochemistry 2016, 117: 1757-1768. PMID: 26682748, DOI: 10.1002/jcb.25474.
- Regulation of HA14‐1 mediated oxidative stress, toxic response, and autophagy by curcumin to enhance apoptotic activity in human embryonic kidney cellsRanjan K, Sharma A, Surolia A, Pathak C. Regulation of HA14‐1 mediated oxidative stress, toxic response, and autophagy by curcumin to enhance apoptotic activity in human embryonic kidney cells. BioFactors 2013, 40: 157-169. PMID: 23559532, DOI: 10.1002/biof.1098.
- Apoptotic potential of Fas‐associated death domain on regulation of cell death regulatory protein cFLIP and death receptor mediated apoptosis in HEK 293T cellsRanjan K, Surolia A, Pathak C. Apoptotic potential of Fas‐associated death domain on regulation of cell death regulatory protein cFLIP and death receptor mediated apoptosis in HEK 293T cells. Journal Of Cell Communication And Signaling 2012, 6: 155-168. PMID: 22791313, PMCID: PMC3421020, DOI: 10.1007/s12079-012-0166-2.