Skip to Main Content
DownloadHi-Res Photo

Kevin Billingsley

MD, MBA, FACS
Professor of Surgery (Oncology); Chief Medical Officer, Yale Cancer Center; Professor, Surgery

Contact Information

Kevin Billingsley, MD, MBA, FACS

Related Links

Yale Medicine

Patient Care

Are you a patient?Please visit the Yale Medicine website for information about the services we offer and making an appointment.View Doctor Profile

Research Summary

Dr. Billingsley's research has focused on optimizing the clinical care of patients with gastrointestinal (GI) tumors. He has served as the surgical investigator in numerous clinical trials. His research portfolio also includes health services and outcomes studies that address a variety of problems faced by GI cancer patients . These studies include work around health care disparities in the treatment of metastatic colorectal cancer as well as a number of investigations in quality of care and the relationship between volume and outcome in complex GI surgical oncology. In more recent years, he has focused on optimizing the technical approaches to liver surgery and the perioperative care of liver surgery patients. Dr. Billingsley's research team clarified the relationship between liver surgery and postoperative blood clotting physiology to diminish the use of unnecessary postoperative transfusion of blood products.

Coauthors

Selected Publications

  • Pandemic Recovery Using a COVID-Minimal Cancer Surgery Pathway.Boffa DJ, Judson BL, Billingsley KG, Galetta D, Fontanez P, Odermatt C, Lindner K, Mitchell MR, Henderson CM, Carafeno T, Pinto J, Wagner JA, Ancuta M, Beley P, Turner AL, Banack T, Laurans MS, Johnson DC, Yoo P, Morton JM, Zurich H, Davis K, Ahuja N. Pandemic Recovery Using a COVID-Minimal Cancer Surgery Pathway. The Annals Of Thoracic Surgery 2020, 110: 718-724. PMID: 32417195, PMCID: PMC7227551, DOI: 10.1016/j.athoracsur.2020.05.003.
  • Yttrium-90 Radioembolization for BCLC Stage C Hepatocellular Carcinoma Comparing Child-Pugh A Versus B7 Patients: Are the Outcomes Equivalent?Zu Q, Schenning RC, Jahangiri Y, Tomozawa Y, Kolbeck KJ, Kaufman JA, Al-Hakim R, Naugler WE, Nabavizadeh N, Kardosh A, Billingsley KG, Mayo SC, Orloff SL, Enestvedt KK, Maynard E, Ahn J, Lhewa D, Farsad K. Yttrium-90 Radioembolization for BCLC Stage C Hepatocellular Carcinoma Comparing Child-Pugh A Versus B7 Patients: Are the Outcomes Equivalent? Cardiovascular And Interventional Radiology 2020, 43: 721-731. PMID: 32140840, DOI: 10.1007/s00270-020-02434-4.
  • Hepatic resection of solitary HCC in the elderly: A unique disease in a growing population.Zarour LR, Billingsley KG, Walker BS, Enestvedt CK, Orloff SL, Maynard E, Mayo SC. Hepatic resection of solitary HCC in the elderly: A unique disease in a growing population. American Journal Of Surgery 2019, 217: 899-905. PMID: 30819401, DOI: 10.1016/j.amjsurg.2019.01.030.
  • Effect of Time to Surgery of Colorectal Liver Metastases on Survival.Chen EY, Mayo SC, Sutton T, Kearney MR, Kardosh A, Vaccaro GM, Billingsley KG, Lopez CD. Effect of Time to Surgery of Colorectal Liver Metastases on Survival. Journal Of Gastrointestinal Cancer 2021, 52: 169-176. PMID: 32086781, PMCID: PMC7900034, DOI: 10.1007/s12029-020-00372-5.
  • Who Undergoes Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy for Appendiceal Cancer? An Analysis of the National Cancer Database.Byrne RM, Gilbert EW, Dewey EN, Herzig DO, Lu KC, Billingsley KG, Deveney KE, Tsikitis VL. Who Undergoes Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy for Appendiceal Cancer? An Analysis of the National Cancer Database. The Journal Of Surgical Research 2019, 238: 198-206. PMID: 30772678, DOI: 10.1016/j.jss.2019.01.039.
  • Tailored treatment of patients with hepatocellular carcinoma with portal vein invasion: experience from a multidisciplinary hepatobiliary tumor program within a NCI comprehensive cancer center.Walcott-Sapp S, Naugler S, Lim JY, Wagner J, Orloff SL, Farsad K, Kolbeck KJ, Kaufman J, Maynard E, Enestvedt CK, Mayo SC, Billingsley KG. Tailored treatment of patients with hepatocellular carcinoma with portal vein invasion: experience from a multidisciplinary hepatobiliary tumor program within a NCI comprehensive cancer center. Journal Of Gastrointestinal Oncology 2018, 9: 1074-1083. PMID: 30603126, PMCID: PMC6286927, DOI: 10.21037/jgo.2018.08.11.
  • Epirubicin and Ifosfamide with Preoperative Radiation for High-Risk Soft Tissue Sarcomas.Lu E, Perlewitz KS, Hayden JB, Hung AY, Doung YC, Davis LE, Mansoor A, Vetto JT, Billingsley KG, Kaempf A, Park B, Ryan CW. Epirubicin and Ifosfamide with Preoperative Radiation for High-Risk Soft Tissue Sarcomas. Annals Of Surgical Oncology 2018, 25: 920-927. PMID: 29388122, DOI: 10.1245/s10434-018-6346-4.
  • Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival.Gast CE, Silk AD, Zarour L, Riegler L, Burkhart JG, Gustafson KT, Parappilly MS, Roh-Johnson M, Goodman JR, Olson B, Schmidt M, Swain JR, Davies PS, Shasthri V, Iizuka S, Flynn P, Watson S, Korkola J, Courtneidge SA, Fischer JM, Jaboin J, Billingsley KG, Lopez CD, Burchard J, Gray J, Coussens LM, Sheppard BC, Wong MH. Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival. Science Advances 2018, 4: eaat7828. PMID: 30214939, PMCID: PMC6135550, DOI: 10.1126/sciadv.aat7828.
  • Cetuximab Combined With Induction Oxaliplatin and Capecitabine, Followed by Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer: SWOG 0713.Leichman CG, McDonough SL, Smalley SR, Billingsley KG, Lenz HJ, Beldner MA, Hezel AF, Velasco MR, Guthrie KA, Blanke CD, Hochster HS. Cetuximab Combined With Induction Oxaliplatin and Capecitabine, Followed by Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer: SWOG 0713. Clinical Colorectal Cancer 2018, 17: e121-e125. PMID: 29233486, PMCID: PMC6598683, DOI: 10.1016/j.clcc.2017.10.008.
  • Preoperative optimization for major hepatic resection.Walcott-Sapp S, Billingsley KG. Preoperative optimization for major hepatic resection. Langenbeck's Archives Of Surgery / Deutsche Gesellschaft Fur Chirurgie 2018, 403: 23-35. PMID: 29150719, DOI: 10.1007/s00423-017-1638-x.
  • Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions.Zarour LR, Anand S, Billingsley KG, Bisson WH, Cercek A, Clarke MF, Coussens LM, Gast CE, Geltzeiler CB, Hansen L, Kelley KA, Lopez CD, Rana SR, Ruhl R, Tsikitis VL, Vaccaro GM, Wong MH, Mayo SC. Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions. Cellular And Molecular Gastroenterology And Hepatology 2017, 3: 163-173. PMID: 28275683, PMCID: PMC5331831, DOI: 10.1016/j.jcmgh.2017.01.006.
  • Nomogram for Predicting Overall Survival and Salvage Abdominoperineal Resection for Patients with Anal Cancer.Tsikitis VL, Lu KC, Kim JS, Billingsley KG, Thomas CR, Herzig DO. Nomogram for Predicting Overall Survival and Salvage Abdominoperineal Resection for Patients with Anal Cancer. Diseases Of The Colon And Rectum 2016, 59: 1-7. PMID: 26651105, DOI: 10.1097/DCR.0000000000000507.
  • Modern technical approaches in resectional hepatic surgery.Michalski CW, Billingsley KG. Modern technical approaches in resectional hepatic surgery. Surgical Oncology Clinics Of North America 2015, 24: 57-72. PMID: 25444469, DOI: 10.1016/j.soc.2014.09.007.
Edit Profile