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Katherine Clark

MD, MBA, FACC

Assistant Professor of Medicine (Cardiovascular Medicine)

Research & Publications
Biography
News

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Selected Publications

Rationale, Design, and Patient Characteristics of a Cluster-Randomized Pragmatic Trial to Improve Mineralocorticoid Antagonist UseClark K, Victoria-Castro A, Ghazi L, Yamamoto Y, Coronel-Moreno C, Kadhim B, Riello R, O'Connor K, Ahmad T, Wilson F, Desai N. Rationale, Design, and Patient Characteristics of a Cluster-Randomized Pragmatic Trial to Improve Mineralocorticoid Antagonist Use. JACC Heart Failure 2023, 12: 322-332. PMID: 37943221, DOI: 10.1016/j.jchf.2023.08.025.
Electronic Health Record Embedded Strategies for Improving Care of Patients With Heart FailureFuery M, Kadhim B, Samsky M, Freeman J, Clark K, Desai N, Wilson F, Ahmed T, Ahmad T. Electronic Health Record Embedded Strategies for Improving Care of Patients With Heart Failure. Current Heart Failure Reports 2023, 20: 280-286. PMID: 37552356, DOI: 10.1007/s11897-023-00614-0.
The EHR Has Exposed an Urgent Moral Imperative to Improve Heart Failure Care ∗Ahmad T, Desai N, Clark K. The EHR Has Exposed an Urgent Moral Imperative to Improve Heart Failure Care ∗. Journal Of The American College Of Cardiology 2023, 81: 1317-1319. PMID: 37019577, DOI: 10.1016/j.jacc.2023.02.040.
Doing Harm by Doing No Harm? Resisting the Urge to Retire GDMT in Older Adults With Heart FailureClark K, Nanna M. Doing Harm by Doing No Harm? Resisting the Urge to Retire GDMT in Older Adults With Heart Failure. Journal Of Cardiac Failure 2023, 29: 445-447. PMID: 36841428, DOI: 10.1016/j.cardfail.2023.02.006.
Shark Sighting in an ElectrocardiogramClark K, Rosenfeld L. Shark Sighting in an Electrocardiogram. JAMA Internal Medicine 2023, 183: 154-155. PMID: 36508202, DOI: 10.1001/jamainternmed.2022.5061.
Moving Toward “Precision” Medicine: Can We Tailor Diabetes Therapy to Patients’ Differential Risks of Future Cardiovascular Disease?Clark K, Morris A. Moving Toward “Precision” Medicine: Can We Tailor Diabetes Therapy to Patients’ Differential Risks of Future Cardiovascular Disease? Journal Of Cardiac Failure 2022, 29: 255-257. PMID: 36529315, DOI: 10.1016/j.cardfail.2022.12.002.
Survival After Heart Transplantation From SARS-CoV-2–Positive DonorsMullan CW, Komlo C, Clark KAA, Sen S, Anwer M, Geirsson A, Ahmad T, Davis RP. Survival After Heart Transplantation From SARS-CoV-2–Positive Donors. JACC Heart Failure 2022, 10: 874-876. PMID: 36328657, PMCID: PMC9555312, DOI: 10.1016/j.jchf.2022.08.006.
Breaking the Bank: The Financial Burden of Living With Heart FailureClark K, Defilippis E, Morris A. Breaking the Bank: The Financial Burden of Living With Heart Failure. Journal Of Cardiac Failure 2022, 28: 1434-1436. PMID: 35870751, DOI: 10.1016/j.cardfail.2022.07.004.
Thirty-Day and 90-Day Episode of Care Spending Following Heart Failure Hospitalization Among Medicare BeneficiariesReinhardt SW, Clark KAA, Xin X, Parzynski CS, Riello R, Sarocco P, Ahmad T, Desai NR. Thirty-Day and 90-Day Episode of Care Spending Following Heart Failure Hospitalization Among Medicare Beneficiaries. Circulation Cardiovascular Quality And Outcomes 2022, 15: e008069. PMID: 35861780, DOI: 10.1161/circoutcomes.121.008069.
Calling time on the use of war metaphors in covid-19Clark K, Altin S. Calling time on the use of war metaphors in covid-19. The BMJ 2022, 377: o1214. PMID: 35562115, DOI: 10.1136/bmj.o1214.
Contemporary US Trends In Heart Transplantation And LVAD Index Hospitalizations: Volumes Increase, Utilization And Cost Vary Over Time, 2015-2018Clark K, Reinhardt S, Chouairi F, Miller E, Kay B, Fuery M, Guha A, Ahmad T, Desai N. Contemporary US Trends In Heart Transplantation And LVAD Index Hospitalizations: Volumes Increase, Utilization And Cost Vary Over Time, 2015-2018. Journal Of Cardiac Failure 2022, 28: s65. DOI: 10.1016/j.cardfail.2022.03.165.
Trends In US Heart Failure Hospitalizations: Increased Volume And Patient Diversity With Decreased Total Costs, 2008-2018Reinhardt S, Clark K, Chouairi F, Miller E, Kay B, Fuery M, Guha A, Ahmad T, Desai N. Trends In US Heart Failure Hospitalizations: Increased Volume And Patient Diversity With Decreased Total Costs, 2008-2018. Journal Of Cardiac Failure 2022, 28: s109-s110. DOI: 10.1016/j.cardfail.2022.03.280.
Patterns of care and outcomes of outpatient percutaneous coronary intervention in the United States: Insights from Nationwide Ambulatory Surgery SampleMilioglou I, Guha A, Chouari F, Chaturvedi A, Clark KAA, Kochar A, Sung JG, Velazquez EJ, Ahmad T, Desai NR. Patterns of care and outcomes of outpatient percutaneous coronary intervention in the United States: Insights from Nationwide Ambulatory Surgery Sample. Hellenic Journal Of Cardiology 2022, 65: 51-52. PMID: 35272018, DOI: 10.1016/j.hjc.2022.03.001.
Moving the Field Forward: Untangling the Impact of Frailty on Patients With Advanced Heart Failure and on Prognosticating OutcomesClark KAA, Nanna MG. Moving the Field Forward: Untangling the Impact of Frailty on Patients With Advanced Heart Failure and on Prognosticating Outcomes. Journal Of Cardiac Failure 2021, 28: 775-777. PMID: 34936895, PMCID: PMC9106896, DOI: 10.1016/j.cardfail.2021.12.006.
Impact of Obesity on Heart Transplantation OutcomesChouairi F, Milner A, Sen S, Guha A, Stewart J, Jastreboff AM, Mori M, Clark KA, Miller PE, Fuery MA, Rogers JG, Notarianni A, Jacoby D, Maulion C, Anwer M, Geirsson A, Desai NR, Ahmad T, Mullan CW. Impact of Obesity on Heart Transplantation Outcomes. Journal Of The American Heart Association 2021, 10: e021346. PMID: 34854316, PMCID: PMC9075353, DOI: 10.1161/jaha.121.021346.
Abstract 12292: Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency CandidatesFuery M, Chouairi F, Natov P, Bhinder J, Chiravuri M, Wilson L, Clark K, Reinhardt S, Mullan C, Miller E, Rogers J, Patel C, Sen S, Geirsson A, Anwer M, Desai N, Ahmad T. Abstract 12292: Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency Candidates. Circulation 2021, 144: a12292-a12292. DOI: 10.1161/circ.144.suppl_1.12292.
Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency CandidatesFuery MA, Chouairi F, Natov P, Bhinder J, Rose Chiravuri M, Wilson L, Clark KA, Reinhardt SW, Mullan C, Miller PE, Davis RP, Rogers JG, Patel CB, Sen S, Geirsson A, Anwer M, Desai N, Ahmad T. Trends and Outcomes of Cardiac Transplantation in the Lowest Urgency Candidates. Journal Of The American Heart Association 2021, 10: e023662. PMID: 34743559, PMCID: PMC9075266, DOI: 10.1161/jaha.121.023662.
Brief report: Cannabis and opioid use disorder among heart failure admissions, 2008–2018Chouairi F, Mullan CW, Ravindra N, Clark KAA, Jaffe EM, Bhinder J, Fuery M, Guha A, Ahmad T, Desai NR. Brief report: Cannabis and opioid use disorder among heart failure admissions, 2008–2018. PLOS ONE 2021, 16: e0255514. PMID: 34591847, PMCID: PMC8483306, DOI: 10.1371/journal.pone.0255514.
Trends in transcatheter and surgical aortic valve replacement in the United States, 2008-2018Clark KA, Chouairi F, Kay B, Reinhardt SW, Miller PE, Fuery M, Mullan CW, Guha A, Ahmad T, Desai NR. Trends in transcatheter and surgical aortic valve replacement in the United States, 2008-2018. American Heart Journal 2021, 243: 87-91. PMID: 34571040, DOI: 10.1016/j.ahj.2021.03.017.
Trends in Heart Failure Hospitalizations in the US from 2008 to 2018Clark KAA, Reinhardt SW, Chouairi F, Miller PE, Kay B, Fuery M, Guha A, Ahmad T, Desai NR. Trends in Heart Failure Hospitalizations in the US from 2008 to 2018. Journal Of Cardiac Failure 2021, 28: 171-180. PMID: 34534665, DOI: 10.1016/j.cardfail.2021.08.020.
Evaluation of Racial and Ethnic Disparities in Cardiac TransplantationChouairi F, Fuery M, Clark KA, Mullan CW, Stewart J, Caraballo C, Clarke J, Sen S, Guha A, Ibrahim NE, Cole RT, Holaday L, Anwer M, Geirsson A, Rogers JG, Velazquez EJ, Desai NR, Ahmad T, Miller PE. Evaluation of Racial and Ethnic Disparities in Cardiac Transplantation. Journal Of The American Heart Association 2021, 10: e021067. PMID: 34431324, PMCID: PMC8649228, DOI: 10.1161/jaha.120.021067.
Mechanical ventilation at the time of heart transplantation and associations with clinical outcomesMiller PE, Mullan CW, Chouairi F, Sen S, Clark KA, Reinhardt S, Fuery M, Anwer M, Geirsson A, Formica R, Rogers JG, Desai NR, Ahmad T. Mechanical ventilation at the time of heart transplantation and associations with clinical outcomes. European Heart Journal Acute Cardiovascular Care 2021, 10: 843-851. PMID: 34389855, PMCID: PMC8557439, DOI: 10.1093/ehjacc/zuab063.
Comparison of Transcatheter and Open Mitral Valve Repair Among Patients With Mitral RegurgitationKay B, Chouairi F, Clark KAA, Reinhardt SW, Fuery M, Guha A, Ahmad T, Kaple RK, Desai NR. Comparison of Transcatheter and Open Mitral Valve Repair Among Patients With Mitral Regurgitation. Mayo Clinic Proceedings 2021, 96: 1522-1529. PMID: 34088415, DOI: 10.1016/j.mayocp.2021.01.029.
National Trends in the Burden of Atrial Fibrillation During Hospital Admissions for Heart FailureReinhardt SW, Chouairi F, Miller PE, Clark KAA, Kay B, Fuery M, Guha A, Freeman JV, Ahmad T, Desai NR, Friedman DJ. National Trends in the Burden of Atrial Fibrillation During Hospital Admissions for Heart Failure. Journal Of The American Heart Association 2021, 10: e019412. PMID: 34013736, PMCID: PMC8483517, DOI: 10.1161/jaha.120.019412.
Outcomes in patients with anthracycline‐induced cardiomyopathy undergoing left ventricular assist devices implantationGuha A, Caraballo C, Jain P, Miller PE, Owusu‐Guha J, Clark KAA, Velazquez EJ, Ahmad T, Baldassarre LA, Addison D, Weintraub NL, Desai NR. Outcomes in patients with anthracycline‐induced cardiomyopathy undergoing left ventricular assist devices implantation. ESC Heart Failure 2021, 8: 2866-2875. PMID: 33982867, PMCID: PMC8318466, DOI: 10.1002/ehf2.13362.
Intercountry Differences in Guideline-Directed Medical Therapy and Outcomes Among Patients With Heart FailureFuery MA, Chouairi F, Januzzi JL, Moe GW, Caraballo C, McCullough M, Miller PE, Reinhardt SW, Clark K, Oseran A, Milner A, Pacor J, Kahn PA, Singh A, Ravindra N, Guha A, Vadlamani L, Kulkarni NS, Fiuzat M, Felker GM, O'Connor CM, Ahmad T, Ezekowitz J, Desai NR. Intercountry Differences in Guideline-Directed Medical Therapy and Outcomes Among Patients With Heart Failure. JACC Heart Failure 2021, 9: 497-505. PMID: 33992564, DOI: 10.1016/j.jchf.2021.02.011.
NINETY-DAY EPISODE OF CARE SPENDING FOLLOWING HEART FAILURE HOSPITALIZATION AMONG MEDICARE BENEFICIARIESReinhardt S, Clark K, Xin X, Parzynski C, Riello R, Sarocco P, Ahmad T, Desai N. NINETY-DAY EPISODE OF CARE SPENDING FOLLOWING HEART FAILURE HOSPITALIZATION AMONG MEDICARE BENEFICIARIES. Journal Of The American College Of Cardiology 2021, 77: 786. DOI: 10.1016/s0735-1097(21)02145-8.
INTRAOPERATIVE MORTALITY AND DISPOSITION OF ELECTIVE PCI: INSIGHTS FROM THE NATIONAL AMBULATORY SURGERY SAMPLEMilioglou I, Chouairi F, Miller P, Ahmad T, Reinhardt S, Kay B, Clark K, Milner A, Pacor J, Caraballo C, Ravindra N, Friedman D, Desai N, Guha A. INTRAOPERATIVE MORTALITY AND DISPOSITION OF ELECTIVE PCI: INSIGHTS FROM THE NATIONAL AMBULATORY SURGERY SAMPLE. Journal Of The American College Of Cardiology 2021, 77: 1020. DOI: 10.1016/s0735-1097(21)02379-2.
LONGITUDINAL AND CONTEMPORARY OUTCOMES OF TEMPORARY MECHANICAL CIRCULATORY SUPPORT IN CARDIAC TRANSPLANTATIONClark K, Chouiari F, Fuery M, Miller P, Mullan C, Reinhardt S, Guha A, Desai N, Ahmad T, Sen S. LONGITUDINAL AND CONTEMPORARY OUTCOMES OF TEMPORARY MECHANICAL CIRCULATORY SUPPORT IN CARDIAC TRANSPLANTATION. Journal Of The American College Of Cardiology 2021, 77: 822. DOI: 10.1016/s0735-1097(21)02181-1.
AN EVALUATION OF RACIAL DISPARITIES IN HEART TRANSPLANTATION OUTCOMESClark K, Chouiari F, Fuery M, Mullan C, Reinhardt S, Guha A, Sen S, Desai N, Ahmad T, Miller P. AN EVALUATION OF RACIAL DISPARITIES IN HEART TRANSPLANTATION OUTCOMES. Journal Of The American College Of Cardiology 2021, 77: 566. DOI: 10.1016/s0735-1097(21)01925-2.
WORSE OUTCOMES IN INDIVIDUALS WITH OBESITY UNDERGOING LEFT VENTRICULAR ASSIST DEVICE IMPLANTATION: A LONGITUDINAL INTERMACS STUDYClark K, Guha A, Oikonomou E, Jastreboff A, Caraballo C, Weintraub N, Ahmad T, Velazquez E, Miller P, Desai N. WORSE OUTCOMES IN INDIVIDUALS WITH OBESITY UNDERGOING LEFT VENTRICULAR ASSIST DEVICE IMPLANTATION: A LONGITUDINAL INTERMACS STUDY. Journal Of The American College Of Cardiology 2021, 77: 552. DOI: 10.1016/s0735-1097(21)01911-2.
Changes in Use of Left Ventricular Assist Devices as Bridge to Transplantation With New Heart Allocation PolicyMullan CW, Chouairi F, Sen S, Mori M, Clark KAA, Reinhardt SW, Miller PE, Fuery MA, Jacoby D, Maulion C, Anwer M, Geirsson A, Mulligan D, Formica R, Rogers JG, Desai NR, Ahmad T. Changes in Use of Left Ventricular Assist Devices as Bridge to Transplantation With New Heart Allocation Policy. JACC Heart Failure 2021, 9: 420-429. PMID: 33714748, DOI: 10.1016/j.jchf.2021.01.010.
Impact of the new heart allocation policy on patients with restrictive, hypertrophic, or congenital cardiomyopathiesChouairi F, Mullan CW, Sen S, Mori M, Fuery M, Elder RW, Lesse J, Norton K, Clark KA, Miller PE, Mulligan D, Formica R, Rogers JG, Jacoby D, Maulion C, Anwer M, Geirsson A, Desai NR, Ahmad T. Impact of the new heart allocation policy on patients with restrictive, hypertrophic, or congenital cardiomyopathies. PLOS ONE 2021, 16: e0247789. PMID: 33651802, PMCID: PMC7924739, DOI: 10.1371/journal.pone.0247789.
Abstract 14563: Improved Outcomes in Patients With Anthracycline-Induced Cardiomyopathy Undergoing Left Ventricular Assist Devices: 10-Year Longitudinal INTERMACS StudyGuha A, Caraballo C, Miller E, Owusu-Guha J, Clark K, Ahmad T, Baldassarre L, Addison D, Weintraub N, Desai N. Abstract 14563: Improved Outcomes in Patients With Anthracycline-Induced Cardiomyopathy Undergoing Left Ventricular Assist Devices: 10-Year Longitudinal INTERMACS Study. Circulation 2020, 142 DOI: 10.1161/circ.142.suppl_3.14563.
Is Left Ventricular Stroke Work Index Useful in the Cardiac Intensive Care Unit?Clark KAA, McNamara RL. Is Left Ventricular Stroke Work Index Useful in the Cardiac Intensive Care Unit? Circulation Cardiovascular Imaging 2020, 13: e012002. PMID: 33190534, DOI: 10.1161/circimaging.120.012002.
Heart Failure With Preserved Ejection FractionClark KAA, Velazquez EJ. Heart Failure With Preserved Ejection Fraction. JAMA 2020, 324: 1506-1508. PMID: 33079136, DOI: 10.1001/jama.2020.15566.
Concurrent Central Venous Stent and Central Venous Access Device Placement Does Not Compromise Stent Patency or Catheter Function in Patients with Malignant Central Venous ObstructionClark K, Chick J, Reddy S, Shin B, Nadolski G, Clark T, Trerotola S. Concurrent Central Venous Stent and Central Venous Access Device Placement Does Not Compromise Stent Patency or Catheter Function in Patients with Malignant Central Venous Obstruction. Journal Of Vascular And Interventional Radiology 2017, 28: 602-607. PMID: 28238580, DOI: 10.1016/j.jvir.2016.12.1222.
Clinician Perception of the Effectiveness of an Automated Early Warning and Response System for Sepsis in an Academic Medical CenterGuidi J, Clark K, Upton M, Faust H, Umscheid C, Lane-Fall M, Mikkelsen M, Schweickert W, Vanzandbergen C, Betesh J, Tait G, Hanish A, Smith K, Feeley D, Fuchs B. Clinician Perception of the Effectiveness of an Automated Early Warning and Response System for Sepsis in an Academic Medical Center. Annals Of The American Thoracic Society 2015, 12: 1514-1519. PMID: 26288388, DOI: 10.1513/annalsats.201503-129oc.
Intracellular signaling mechanisms associated with CD47 modified surfacesFinley M, Clark K, Alferiev I, Levy R, Stachelek S. Intracellular signaling mechanisms associated with CD47 modified surfaces. Biomaterials 2013, 34: 8640-8649. PMID: 23948164, PMCID: PMC3804223, DOI: 10.1016/j.biomaterials.2013.07.088.
Angina Pectoris or Myocardial Infarctions, Pulmonary Arteriovenous Malformations, Hereditary Hemorrhagic Telangiectasia, and Paradoxical EmboliClark K, Pyeritz R, Trerotola S. Angina Pectoris or Myocardial Infarctions, Pulmonary Arteriovenous Malformations, Hereditary Hemorrhagic Telangiectasia, and Paradoxical Emboli. The American Journal Of Cardiology 2013, 112: 731-734. PMID: 23707042, DOI: 10.1016/j.amjcard.2013.04.052.
Abstract 493: The Regulation of Thrombospondin-1 Release through SIRPa-CD47 Mediated-Signaling in PlateletsClark K, Johnston I, Raouva L, Fishbein I, Levy R, Stachelek S. Abstract 493: The Regulation of Thrombospondin-1 Release through SIRPa-CD47 Mediated-Signaling in Platelets. Arteriosclerosis Thrombosis And Vascular Biology 2013, 33 DOI: 10.1161/atvb.33.suppl_1.a493.
Cyanylated Cysteine: A Covalently Attached Vibrational Probe of Protein−Lipid ContactsMcMahon H, Alfieri K, Clark K, Londergan C. Cyanylated Cysteine: A Covalently Attached Vibrational Probe of Protein−Lipid Contacts. The Journal Of Physical Chemistry Letters 2010, 1: 850-855. PMID: 20228945, PMCID: PMC2836368, DOI: 10.1021/jz1000177.
Cyanylated Cysteine Is a Site-Specific Vibrational Probe of Disorder-to-Order Transitions In Helical Protein DomainsEdelstein L, Clark K, Londergan C. Cyanylated Cysteine Is a Site-Specific Vibrational Probe of Disorder-to-Order Transitions In Helical Protein Domains. Biophysical Journal 2009, 96: 320a. DOI: 10.1016/j.bpj.2008.12.1603.

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Katherine Clark

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