Kartik Pattabiraman, MD/PhD

• Nenad Sestan
• Stephen Waxman

Cerebral Cortex; Developmental Disabilities; Embryonic and Fetal Development; Schizophrenia; Gene Regulatory Networks

Child/Adolescent Health

• Transcriptional regulation of enhancers active in protodomains of the developing cerebral cortex.Pattabiraman K, Golonzhka O, Lindtner S, Nord AS, Taher L, Hoch R, Silberberg SN, Zhang D, Chen B, Zeng H, Pennacchio LA, Puelles L, Visel A, Rubenstein JL. Transcriptional regulation of enhancers active in protodomains of the developing cerebral cortex. Neuron 2014, 82: 989-1003 PubMed ID: 24814534, PMCID: PMC4104757, DOI: 10.1016/j.neuron.2014.04.014.
• Genomic perspectives of transcriptional regulation in forebrain development.Nord AS, Pattabiraman K, Visel A, Rubenstein JL. Genomic perspectives of transcriptional regulation in forebrain development. Neuron 2015, 85: 27-47 PubMed ID: 25569346, PMCID: PMC4438709, DOI: 10.1016/j.neuron.2014.11.011.
• A high-resolution enhancer atlas of the developing telencephalon.Visel A, Taher L, Girgis H, May D, Golonzhka O, Hoch RV, McKinsey GL, Pattabiraman K, Silberberg SN, Blow MJ, Hansen DV, Nord AS, Akiyama JA, Holt A, Hosseini R, Phouanenavong S, Plajzer-Frick I, Shoukry M, Afzal V, Kaplan T, Kriegstein AR, Rubin EM, Ovcharenko I, Pennacchio LA, Rubenstein JL. A high-resolution enhancer atlas of the developing telencephalon. Cell 2013, 152: 895-908 PubMed ID: 23375746, PMCID: PMC3660042, DOI: 10.1016/j.cell.2012.12.041.
• The evolution of the human brain and disease susceptibility.Pattabiraman K, Muchnik SK, Sestan N. The evolution of the human brain and disease susceptibility. Current Opinion In Genetics & Development 2020, 65: 91-97 PubMed ID: 32629339, DOI: 10.1016/j.gde.2020.05.004.
• Hominini-specific regulation of CBLN2 increases prefrontal spinogenesis.Shibata M, Pattabiraman K, Muchnik SK, Kaur N, Morozov YM, Cheng X, Waxman SG, Sestan N. Hominini-specific regulation of CBLN2 increases prefrontal spinogenesis. Nature 2021, 598: 489-494 PubMed ID: 34599306, DOI: 10.1038/s41586-021-03952-y.
• Regulation of prefrontal patterning and connectivity by retinoic acid.Shibata M, Pattabiraman K, Lorente-Galdos B, Andrijevic D, Kim SK, Kaur N, Muchnik SK, Xing X, Santpere G, Sousa AMM, Sestan N. Regulation of prefrontal patterning and connectivity by retinoic acid. Nature 2021, 598: 483-488 PubMed ID: 34599305, DOI: 10.1038/s41586-021-03953-x.