Julia Shi, MD
Assistant Clinical Professor of Medicine
Research & Publications
Biography
Research Summary
I participate in numerous NIH sponsored research projects in substance abuse, am a clinical investigator for the Psychotherapy Development Center and Yale Behavioral Pharmacology Laboratory.
Coauthors
Selected Publications
- A pilot study of primary-care-based buprenorphine maintenance for heroin dependence.O'Connor PG, Oliveto AH, Shi JM, Triffleman E, Carroll KM, Kosten TR, Rounsaville BJ. A pilot study of primary-care-based buprenorphine maintenance for heroin dependence. The American Journal Of Drug And Alcohol Abuse 1996, 22:523-31.
- Three methods of opioid detoxification in a primary care setting. A randomized trial.O'Connor PG, Carroll KM, Shi JM, Schottenfeld RS, Kosten TR, Rounsaville BJ. Three methods of opioid detoxification in a primary care setting. A randomized trial. Annals Of Internal Medicine 1997, 127:526-30.
- A randomized trial of buprenorphine maintenance for heroin dependence in a primary care clinic for substance users versus a methadone clinic.O'Connor PG, Oliveto AH, Shi JM, Triffleman EG, Carroll KM, Kosten TR, Rounsaville BJ, Pakes JA, Schottenfeld RS. A randomized trial of buprenorphine maintenance for heroin dependence in a primary care clinic for substance users versus a methadone clinic. The American Journal Of Medicine 1998, 105:100-5.
- Tuberculosis chemoprophylaxis using a liquid isoniazid-methadone admixture for drug users in methadone maintenance.O'Connor PG, Shi JM, Henry S, Durante AJ, Friedman L, Selwyn PA. Tuberculosis chemoprophylaxis using a liquid isoniazid-methadone admixture for drug users in methadone maintenance. Addiction (Abingdon, England) 1999, 94:1071-5.
- Targeting behavioral therapies to enhance naltrexone treatment of opioid dependence: efficacy of contingency management and significant other involvement.Carroll KM, Ball SA, Nich C, O'Connor PG, Eagan DA, Frankforter TL, Triffleman EG, Shi J, Rounsaville BJ. Targeting behavioral therapies to enhance naltrexone treatment of opioid dependence: efficacy of contingency management and significant other involvement. Archives Of General Psychiatry 2001, 58:755-61.
- Predictors of nonadherence to HIV-related medication regimens during methadone stabilization.Avants SK, Margolin A, Warburton LA, Hawkins KA, Shi J. Predictors of nonadherence to HIV-related medication regimens during methadone stabilization. The American Journal On Addictions / American Academy Of Psychiatrists In Alcoholism And Addictions 2001, 10:69-78.
- A randomized clinical trial of a manual-guided risk reduction intervention for HIV-positive injection drug users.Margolin A, Avants SK, Warburton LA, Hawkins KA, Shi J. A randomized clinical trial of a manual-guided risk reduction intervention for HIV-positive injection drug users. Health Psychology : Official Journal Of The Division Of Health Psychology, American Psychological Association 2003, 22:223-8.
- Efficacy of disulfiram and cognitive behavior therapy in cocaine-dependent outpatients: a randomized placebo-controlled trial.Carroll KM, Fenton LR, Ball SA, Nich C, Frankforter TL, Shi J, Rounsaville BJ. Efficacy of disulfiram and cognitive behavior therapy in cocaine-dependent outpatients: a randomized placebo-controlled trial. Archives Of General Psychiatry 2004, 61:264-72.
- Lack of an effect of atazanavir on steady-state pharmacokinetics of methadone in patients chronically treated for opiate addiction.Friedland G, Andrews L, Schreibman T, Agarwala S, Daley L, Child M, Shi J, Wang Y, O'Mara E. Lack of an effect of atazanavir on steady-state pharmacokinetics of methadone in patients chronically treated for opiate addiction. AIDS (London, England) 2005, 19:1635-41.
- Modeling the effect of alcohol on smoking lapse behavior.McKee SA, Krishnan-Sarin S, Shi J, Mase T, O'Malley SS. Modeling the effect of alcohol on smoking lapse behavior. Psychopharmacology 2006, 189:201-10.
- High rate of negative results of tuberculin and QuantiFERON tests among individuals with a history of positive skin test results.Friedman LN, Nash ER, Bryant J, Henry S, Shi J, D'Amato J, Khaled GH, Russi MB, O'Connor PG, Edberg SC, Pisani MA, Cain HC, Tanoue L, Weissman DN. High rate of negative results of tuberculin and QuantiFERON tests among individuals with a history of positive skin test results. Infection Control And Hospital Epidemiology 2006, 27:436-41.
- Family history of alcoholism influences naltrexone-induced reduction in alcohol drinking.Krishnan-Sarin S, Krystal JH, Shi J, Pittman B, O'Malley SS. Family history of alcoholism influences naltrexone-induced reduction in alcohol drinking. Biological Psychiatry 2007, 62:694-7.
- Effect of transdermal nicotine replacement on alcohol responses and alcohol self-administration.McKee SA, O'Malley SS, Shi J, Mase T, Krishnan-Sarin S. Effect of transdermal nicotine replacement on alcohol responses and alcohol self-administration. Psychopharmacology 2008, 196:189-200.
- Varenicline reduces alcohol self-administration in heavy-drinking smokers.McKee SA, Harrison EL, O'Malley SS, Krishnan-Sarin S, Shi J, Tetrault JM, Picciotto MR, Petrakis IL, Estevez N, Balchunas E. Varenicline reduces alcohol self-administration in heavy-drinking smokers. Biological Psychiatry 2009, 66:185-90.
- Alcohol expectancy increases positive responses to cigarettes in young, escalating smokers.McKee SA, Harrison EL, Shi J. Alcohol expectancy increases positive responses to cigarettes in young, escalating smokers. Psychopharmacology 2010, 210:355-64.
- Developing and validating a human laboratory model to screen medications for smoking cessation.McKee SA, Weinberger AH, Shi J, Tetrault J, Coppola S. Developing and validating a human laboratory model to screen medications for smoking cessation. Nicotine & Tobacco Research : Official Journal Of The Society For Research On Nicotine And Tobacco 2012, 14:1362-71.
- Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: a randomized placebo-controlled trial.Carroll KM, Nich C, Shi JM, Eagan D, Ball SA. Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: a randomized placebo-controlled trial. Drug And Alcohol Dependence 2012, 126:224-31.
- A preliminary study on the effect of combined nicotine replacement therapy on alcohol responses and alcohol self-administration.Udo T, Harrison EL, Shi J, Tetrault J, McKee SA. A preliminary study on the effect of combined nicotine replacement therapy on alcohol responses and alcohol self-administration. The American Journal On Addictions / American Academy Of Psychiatrists In Alcoholism And Addictions 2013, 22:590-7.
- Ethyl glucuronide and ethyl sulfate assays in clinical trials, interpretation, and limitations: results of a dose ranging alcohol challenge study and 2 clinical trials.Jatlow PI, Agro A, Wu R, Nadim H, Toll BA, Ralevski E, Nogueira C, Shi J, Dziura JD, Petrakis IL, O'Malley SS. Ethyl glucuronide and ethyl sulfate assays in clinical trials, interpretation, and limitations: results of a dose ranging alcohol challenge study and 2 clinical trials. Alcoholism, Clinical And Experimental Research 2014, 38:2056-65.
- N-methyl-D-aspartate receptor antagonism has differential effects on alcohol craving and drinking in heavy drinkers.Krishnan-Sarin S, O'Malley SS, Franco N, Cavallo DA, Morean M, Shi J, Pittman B, Krystal JH. N-methyl-D-aspartate receptor antagonism has differential effects on alcohol craving and drinking in heavy drinkers. Alcoholism, Clinical And Experimental Research 2015, 39:300-7.
- A randomized factorial trial of disulfiram and contingency management to enhance cognitive behavioral therapy for cocaine dependence.Carroll KM, Nich C, Petry NM, Eagan DA, Shi JM, Ball SA. A randomized factorial trial of disulfiram and contingency management to enhance cognitive behavioral therapy for cocaine dependence. Drug And Alcohol Dependence 2016, 160:135-42.
- Effect of Varenicline Combined with High-Dose Alcohol on Craving, Subjective Intoxication, Perceptual Motor Response, and Executive Cognitive Function in Adults with Alcohol Use Disorders: Preliminary Findings.Verplaetse TL, Pittman BP, Shi JM, Tetrault JM, Coppola S, McKee SA. Effect of Varenicline Combined with High-Dose Alcohol on Craving, Subjective Intoxication, Perceptual Motor Response, and Executive Cognitive Function in Adults with Alcohol Use Disorders: Preliminary Findings. Alcoholism, Clinical And Experimental Research 2016, 40:1567-76.
- Effect of Lowering the Dose of Varenicline on Alcohol Self-administration in Drinkers With Alcohol Use Disorders.Verplaetse TL, Pittman BP, Shi JM, Tetrault JM, Coppola S, McKee SA. Effect of Lowering the Dose of Varenicline on Alcohol Self-administration in Drinkers With Alcohol Use Disorders. Journal Of Addiction Medicine 2016, 10:166-73.
- Onsite treatment of HCV infection with direct acting antivirals within an opioid treatment program.Butner JL, Gupta N, Fabian C, Henry S, Shi JM, Tetrault JM. Onsite treatment of HCV infection with direct acting antivirals within an opioid treatment program. Journal Of Substance Abuse Treatment 2017, 75:49-53.
- Effect of doxazosin on stress reactivity and the ability to resist smoking.Verplaetse TL, Weinberger AH, Oberleitner LM, Smith KM, Pittman BP, Shi JM, Tetrault JM, Lavery ME, Picciotto MR, McKee SA. Effect of doxazosin on stress reactivity and the ability to resist smoking. Journal Of Psychopharmacology (Oxford, England) 2017, 31:830-840.
- An investigation of an open-access model for scaling up methadone maintenance treatment.Madden LM, Farnum SO, Eggert KF, Quanbeck AR, Freeman R, Ball SA, Schottenfeld RS, Shi JM, Savage ME, Barry DT. An investigation of an open-access model for scaling up methadone maintenance treatment. Addiction (Abingdon, England) 2018, 113:1450-1458.
- Effects of Varenicline Alone and in Combination With Low-dose Naltrexone on Alcohol-primed Smoking in Heavy-drinking Tobacco Users: A Preliminary Laboratory Study.Roberts W, Shi JM, Tetrault JM, McKee SA. Effects of Varenicline Alone and in Combination With Low-dose Naltrexone on Alcohol-primed Smoking in Heavy-drinking Tobacco Users: A Preliminary Laboratory Study. Journal Of Addiction Medicine 2018, 12:227-233.
- Galantamine and Computerized Cognitive Behavioral Therapy for Cocaine Dependence: A Randomized Clinical Trial.Carroll KM, Nich C, DeVito EE, Shi JM, Sofuoglu M. Galantamine and Computerized Cognitive Behavioral Therapy for Cocaine Dependence: A Randomized Clinical Trial. The Journal Of Clinical Psychiatry 2018, 79.
- Pilot investigation of the effect of carvedilol on stress-precipitated smoking-lapse behavior.Verplaetse TL, Weinberger AH, Ashare RL, Pittman BP, Shi JM, Tetrault JM, Lavery M, McKee SA. Pilot investigation of the effect of carvedilol on stress-precipitated smoking-lapse behavior. Journal Of Psychopharmacology (Oxford, England) 2018, 32:1003-1009.
- Randomized pilot trial of Web-based cognitive-behavioral therapy adapted for use in office-based buprenorphine maintenance.Shi JM, Henry SP, Dwy SL, Orazietti SA, Carroll KM. Randomized pilot trial of Web-based cognitive-behavioral therapy adapted for use in office-based buprenorphine maintenance. Substance Abuse : Official Publication Of The Association For Medical Education And Research In Substance Abuse 2019, 40:132-135.
- The Kappa Opioid Receptor Is Associated With Naltrexone-Induced Reduction of Drinking and Craving.de Laat B, Goldberg A, Shi J, Tetrault JM, Nabulsi N, Zheng MQ, Najafzadeh S, Gao H, Kapinos M, Ropchan J, O'Malley SS, Huang Y, Morris ED, Krishnan-Sarin S. The Kappa Opioid Receptor Is Associated With Naltrexone-Induced Reduction of Drinking and Craving. Biological Psychiatry 2019, 86:864-871.
- Galantamine to reduce relapse after agonist taper for individuals with opioid use disorder.Sofuoglu M, Shi JM, Carroll KM. Galantamine to reduce relapse after agonist taper for individuals with opioid use disorder. Drug And Alcohol Dependence 2019, 203:98.
- Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial.Krishnan-Sarin S, O'Malley SS, Franco N, Cavallo DA, Tetrault JM, Shi J, Gueorguieva R, Pittman B, Krystal JH. Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial. Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology 2020, 45:319-326.