Jonathan Siner, MD

• Aidan Milner
• Akiko Iwasaki
• Albert C Shaw
• Albert Ko
• Alexander B. Pine
• Alfred Lee
• Allen Hsiao
• Ami Rubinowitz
• Avinainder Singh
• Bishwajit Bhattacharya
• Cassius Iyad Ochoa Chaar
• Charles Dela Cruz
• Charles Matouk
• Charles Torre
• Chris Sankey
• Christina Price
• Christopher Tormey
• Danielle Antin-Ozerkis
• David Y Hwang
• Elaine Fajardo
• Emily J. Gilmore
• Eric Chang
• Eric Velazquez
• Erica Herzog
• Frederick Warner
• Gail McAvay
• George Goshua
• Gordon Sze
• Guido Falcone
• Hanming Zhang
• Harlan Krumholz
• Heather Warner
• Henry Rinder
• Hyung Chun
• Jack Elias
• Jacob M McPadden
• Jennifer Ahjin Kim
• John Hwa
• Jon Koff
• Jonathan Rothberg
• Joseph Brennan
• Joseph Schindler
• Kathryn Engle
• Kevin Gobeske
• Kevin Schuster
• Kevin Sheth
• Kimberly Davis
• Lauren Ferrante
• Lauren Sansing
• Linda Maerz
• Margaret Pisani
• Mark David Siegel
• Matthew Bizzarro
• Merceditas Villanueva
• Michael Mankbadi
• Mridu Gulati
• Murat Gunel
• Natalia Neparidze
• Nihar Desai
• Nils Petersen
• Noffar Bar
• Nwanmegha Young
• Patrick Young
• Rebecca Pulk
• Richard Bucala
• Richard Taylor
• Robert Bona
• Robert Homer
• Roy S. Herbst
• Ruth R Montgomery
• Sarwat Chaudhry
• Serena Spudich
• Shelli Farhadian
• Shyoko Honiden
• Stanley Rosenbaum
• Stephanie Halene
• Stephen Wang
• Thomas Balcezak
• Thomas Durant
• Wade Schulz
• Xuchen Zhang
• Yuxin Liu

Hospital Administration; Intensive Care Units; Pulmonary Medicine; Safety Management; Sepsis; Translational Medical Research

• Abnormalities of Aspiration and Swallowing Function in Survivors of Acute Respiratory Failure.Langmore SE, Krisciunas GP, Warner H, White SD, Dvorkin D, Fink D, McNally E, Scheel R, Higgins C, Levitt JE, McKeehan J, Deane S, Siner JM, Vojnik R, Moss M. Abnormalities of Aspiration and Swallowing Function in Survivors of Acute Respiratory Failure. Dysphagia 2021, 36: 831-841 PubMed ID: 33156398, DOI: 10.1007/s00455-020-10199-8.
• Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: A propensity score-matched analysis.Meizlish ML, Goshua G, Liu Y, Fine R, Amin K, Chang E, DeFilippo N, Keating C, Liu Y, Mankbadi M, McManus D, Wang SY, Price C, Bona RD, Ochoa Chaar CI, Chun HJ, Pine AB, Rinder HM, Siner JM, Neuberg DS, Owusu KA, Lee AI. Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: A propensity score-matched analysis. American Journal Of Hematology 2021, 96: 471-479 PubMed ID: 33476420, PMCID: PMC8013588, DOI: 10.1002/ajh.26102.
• Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: a propensity score-matched analysis.Meizlish ML, Goshua G, Liu Y, Fine R, Amin K, Chang E, DeFilippo N, Keating C, Liu Y, Mankbadi M, McManus D, Wang S, Price C, Bona RD, Chaar CIO, Chun HJ, Pine AB, Rinder HM, Siner J, Neuberg DS, Owusu KA, Lee AI. Intermediate-dose anticoagulation, aspirin, and in-hospital mortality in COVID-19: a propensity score-matched analysis. MedRxiv : The Preprint Server For Health Sciences 2021 PubMed ID: 33469595, PMCID: PMC7814841, DOI: 10.1101/2021.01.12.21249577.
• Lung-Protective Ventilation Over 6 Years at a Large Academic Medical Center: An Evaluation of Trends, Adherence, and Perceptions of Benefit.Gao CA, Howard FM, Siner JM, Candido TD, Ferrante LE. Lung-Protective Ventilation Over 6 Years at a Large Academic Medical Center: An Evaluation of Trends, Adherence, and Perceptions of Benefit. Critical Care Explorations 2021, 3: e0325 PubMed ID: 33458691, PMCID: PMC7803935, DOI: 10.1097/CCE.0000000000000325.
• Clinical characteristics and outcomes for 7,995 patients with SARS-CoV-2 infection.McPadden J, Warner F, Young HP, Hurley NC, Pulk RA, Singh A, Durant TJS, Gong G, Desai N, Haimovich A, Taylor RA, Gunel M, Dela Cruz CS, Farhadian SF, Siner J, Villanueva M, Churchwell K, Hsiao A, Torre CJ, Velazquez EJ, Herbst RS, Iwasaki A, Ko AI, Mortazavi BJ, Krumholz HM, Schulz WL. Clinical characteristics and outcomes for 7,995 patients with SARS-CoV-2 infection. PloS One 2021, 16: e0243291 PubMed ID: 33788846, PMCID: PMC8011821, DOI: 10.1371/journal.pone.0243291.
• Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study.Goshua G, Pine AB, Meizlish ML, Chang CH, Zhang H, Bahel P, Baluha A, Bar N, Bona RD, Burns AJ, Dela Cruz CS, Dumont A, Halene S, Hwa J, Koff J, Menninger H, Neparidze N, Price C, Siner JM, Tormey C, Rinder HM, Chun HJ, Lee AI. Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study. The Lancet. Haematology 2020, 7: e575-e582 PubMed ID: 32619411, PMCID: PMC7326446, DOI: 10.1016/S2352-3026(20)30216-7.
• Development of an Accurate Bedside Swallowing Evaluation Decision Tree Algorithm for Detecting Aspiration in Acute Respiratory Failure Survivors.Moss M, White SD, Warner H, Dvorkin D, Fink D, Gomez-Taborda S, Higgins C, Krisciunas GP, Levitt JE, McKeehan J, McNally E, Rubio A, Scheel R, Siner JM, Vojnik R, Langmore SE. Development of an Accurate Bedside Swallowing Evaluation Decision Tree Algorithm for Detecting Aspiration in Acute Respiratory Failure Survivors. Chest 2020, 158: 1923-1933 PubMed ID: 32721404, PMCID: PMC7674978, DOI: 10.1016/j.chest.2020.07.051.
• Ventilator Sharing Using Volume-controlled Ventilation during the COVID-19 Pandemic.Milner A, Siner JM, Balcezak T, Fajardo E. Ventilator Sharing Using Volume-controlled Ventilation during the COVID-19 Pandemic. American Journal Of Respiratory And Critical Care Medicine 2020, 202: 1317-1319 PubMed ID: 32744456, PMCID: PMC7605199, DOI: 10.1164/rccm.202006-2452LE.
• The Association Between Endotracheal Tube Size and Aspiration (During Flexible Endoscopic Evaluation of Swallowing) in Acute Respiratory Failure Survivors.Krisciunas GP, Langmore SE, Gomez-Taborda S, Fink D, Levitt JE, McKeehan J, McNally E, Scheel R, Rubio AC, Siner JM, Vojnik R, Warner H, White SD, Moss M. The Association Between Endotracheal Tube Size and Aspiration (During Flexible Endoscopic Evaluation of Swallowing) in Acute Respiratory Failure Survivors. Critical Care Medicine 2020, 48: 1604-1611 PubMed ID: 32804785, PMCID: PMC7644217, DOI: 10.1097/CCM.0000000000004554.
• Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill Patients.Sheth KN, Mazurek MH, Yuen MM, Cahn BA, Shah JT, Ward A, Kim JA, Gilmore EJ, Falcone GJ, Petersen N, Gobeske KT, Kaddouh F, Hwang DY, Schindler J, Sansing L, Matouk C, Rothberg J, Sze G, Siner J, Rosen MS, Spudich S, Kimberly WT. Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill Patients. JAMA Neurology 2020 PubMed ID: 32897296, PMCID: PMC7489395, DOI: 10.1001/jamaneurol.2020.3263.
• Relationship Between Laryngeal Sensation, Length of Intubation, and Aspiration in Patients with Acute Respiratory Failure.Borders JC, Fink D, Levitt JE, McKeehan J, McNally E, Rubio A, Scheel R, Siner JM, Taborda SG, Vojnik R, Warner H, White SD, Langmore SE, Moss M, Krisciunas GP. Relationship Between Laryngeal Sensation, Length of Intubation, and Aspiration in Patients with Acute Respiratory Failure. Dysphagia 2019, 34: 521-528 PubMed ID: 30694412, PMCID: PMC6660370, DOI: 10.1007/s00455-019-09980-1.
• Evaluation of Swallow Function Post-Extubation: Is It Necessary to Wait 24 Hours?Leder SB, Warner HL, Suiter DM, Young NO, Bhattacharya B, Siner JM, Davis KA, Maerz LL, Rosenbaum SH, Marshall PS, Pisani MA, Siegel MD, Brennan JJ, Schuster KM. Evaluation of Swallow Function Post-Extubation: Is It Necessary to Wait 24 Hours? The Annals Of Otology, Rhinology, And Laryngology 2019, 128: 619-624 PubMed ID: 30841709, DOI: 10.1177/0003489419836115.
• Principles of Geriatric Critical CareSiner J, Pisani M. Respiratory Critical Care in the Elderly. Eds. S Akhtar & S. Rosenbaum, Principles of Geriatric Critical Care (pp 51-62). Cambridge University Press. 2018.
• "Deterioration to Door Time": An Exploratory Analysis of Delays in Escalation of Care for Hospitalized Patients.Sankey CB, McAvay G, Siner JM, Barsky CL, Chaudhry SI. "Deterioration to Door Time": An Exploratory Analysis of Delays in Escalation of Care for Hospitalized Patients. Journal Of General Internal Medicine 2016, 31: 895-900 PubMed ID: 26969311, PMCID: PMC4945556, DOI: 10.1007/s11606-016-3654-x.
• Oral Alimentation in Neonatal and Adult Populations Requiring High-Flow Oxygen via Nasal Cannula.Leder SB, Siner JM, Bizzarro MJ, McGinley BM, Lefton-Greif MA. Oral Alimentation in Neonatal and Adult Populations Requiring High-Flow Oxygen via Nasal Cannula. Dysphagia 2016, 31: 154-9 PubMed ID: 26590570, DOI: 10.1007/s00455-015-9669-3.
• FIRST, "KNOW" HARM: Response to Letter to the Editor.Bizzarro MJ, Lefton-Greif MA, McGinley BM, Siner JM. FIRST, "KNOW" HARM: Response to Letter to the Editor. Dysphagia 2016, 31: 783-785 PubMed ID: 27638423, DOI: 10.1007/s00455-016-9748-0.
• Prospective Validation of Central Line-Days Derived From an Electronic Medical Record System.Boyce JM, Paci G, Feidner C, Hubbard L, Devin L, Reilly L, Gentile A, Siner JM. Prospective Validation of Central Line-Days Derived From an Electronic Medical Record System. Infection Control And Hospital Epidemiology 2015, 36: 1098-9 PubMed ID: 26054019, DOI: 10.1017/ice.2015.137.
• Advances and Challenges in Critical Care Medicine.Honiden S, Siner JM. Advances and Challenges in Critical Care Medicine. Clinics In Chest Medicine 2015, 36: xv-xvi PubMed ID: 26304290, DOI: 10.1016/j.ccm.2015.07.002.
• Attitudes of Pulmonary and Critical Care Training Program Directors toward Quality Improvement Education.Kahn JM, Feemster LC, Fruci CM, Hyzy RC, Savant AP, Siner JM, Weiss CH, Patel B. Attitudes of Pulmonary and Critical Care Training Program Directors toward Quality Improvement Education. Annals Of The American Thoracic Society 2015, 12: 587-90 PubMed ID: 25723649, PMCID: PMC5466183, DOI: 10.1513/AnnalsATS.201501-061BC.
• Clinical Reasoning and Risk in the Intensive Care Unit.Connors GR, Siner JM. Clinical Reasoning and Risk in the Intensive Care Unit. Clinics In Chest Medicine 2015, 36: 449-59 PubMed ID: 26304282, DOI: 10.1016/j.ccm.2015.05.016.
• Adverse Event Reporting and Quality Improvement in the Intensive Care Unit.Heavner JJ, Siner JM. Adverse Event Reporting and Quality Improvement in the Intensive Care Unit. Clinics In Chest Medicine 2015, 36: 461-7 PubMed ID: 26304283, DOI: 10.1016/j.ccm.2015.05.005.
• Protocols and Hospital Mortality in Critically Ill Patients: The United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study.Sevransky JE, Checkley W, Herrera P, Pickering BW, Barr J, Brown SM, Chang SY, Chong D, Kaufman D, Fremont RD, Girard TD, Hoag J, Johnson SB, Kerlin MP, Liebler J, O'Brien J, O'Keefe T, Park PK, Pastores SM, Patil N, Pietropaoli AP, Putman M, Rice TW, Rotello L, Siner J, Sajid S, Murphy DJ, Martin GS. Protocols and Hospital Mortality in Critically Ill Patients: The United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study. Critical Care Medicine 2015, 43: 2076-84 PubMed ID: 26110488, PMCID: PMC5673100, DOI: 10.1097/CCM.0000000000001157.
• Protocol-Based Care versus Individualized Management of Patients in the Intensive Care Unit.Siner JM, Connors GR. Protocol-Based Care versus Individualized Management of Patients in the Intensive Care Unit. Seminars In Respiratory And Critical Care Medicine 2015, 36: 870-7 PubMed ID: 26595047, DOI: 10.1055/s-0035-1566157.
• Structure, process, and annual ICU mortality across 69 centers: United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study.Checkley W, Martin GS, Brown SM, Chang SY, Dabbagh O, Fremont RD, Girard TD, Rice TW, Howell MD, Johnson SB, O'Brien J, Park PK, Pastores SM, Patil NT, Pietropaoli AP, Putman M, Rotello L, Siner J, Sajid S, Murphy DJ, Sevransky JE. Structure, process, and annual ICU mortality across 69 centers: United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study. Critical Care Medicine 2014, 42: 344-56 PubMed ID: 24145833, PMCID: PMC4035482, DOI: 10.1097/CCM.0b013e3182a275d7.
• A tale of two ligands: angiopoietins, the endothelium, and outcomes.Siner JM. A tale of two ligands: angiopoietins, the endothelium, and outcomes. Critical Care (London, England) 2013, 17: 1007 PubMed ID: 24131798, PMCID: PMC4057381, DOI: 10.1186/cc13066.
• An exogenous cough.Siner JM. An exogenous cough. Critical Care Medicine 2013, 41: 929-30 PubMed ID: 23425835, DOI: 10.1097/CCM.0b013e31827bf4ee.
• Role of semaphorin 7a signaling in transforming growth factor β1-induced lung fibrosis and scleroderma-related interstitial lung disease.Gan Y, Reilkoff R, Peng X, Russell T, Chen Q, Mathai SK, Homer R, Gulati M, Siner J, Elias J, Bucala R, Herzog E. Role of semaphorin 7a signaling in transforming growth factor β1-induced lung fibrosis and scleroderma-related interstitial lung disease. Arthritis And Rheumatism 2011, 63: 2484-94 PubMed ID: 21484765, PMCID: PMC3651701, DOI: 10.1002/art.30386.
• Success stories: use of patient vignettes to assess the ability of physicians to predict extubation success.Siner JM, Siegel MD. Success stories: use of patient vignettes to assess the ability of physicians to predict extubation success. Respiratory Care 2011, 56: 1050-1 PubMed ID: 21740729, DOI: 10.4187/respcare.01438.
• Spontaneous hemothorax and recurrent hemoptysis in a 26-year-old man with skin lesions.Selim B, Lane CR, Rubinowitz AN, Siner JM. Spontaneous hemothorax and recurrent hemoptysis in a 26-year-old man with skin lesions. Chest 2010, 137: 480-3 PubMed ID: 20133296, DOI: 10.1378/chest.09-1030.
• Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype.Mathai SK, Gulati M, Peng X, Russell TR, Shaw AC, Rubinowitz AN, Murray LA, Siner JM, Antin-Ozerkis DE, Montgomery RR, Reilkoff RA, Bucala RJ, Herzog EL. Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype. Laboratory Investigation; A Journal Of Technical Methods And Pathology 2010, 90: 812-23 PubMed ID: 20404807, PMCID: PMC3682419, DOI: 10.1038/labinvest.2010.73.
• Elevated serum angiopoietin 2 levels are associated with increased mortality in sepsis.Siner JM, Bhandari V, Engle KM, Elias JA, Siegel MD. Elevated serum angiopoietin 2 levels are associated with increased mortality in sepsis. Shock (Augusta, Ga.) 2009, 31: 348-53 PubMed ID: 18791490, DOI: 10.1097/SHK.0b013e318188bd06.
• Mechanical ventilation and acute respiratory distress syndrome in older patients.Siner JM, Pisani MA. Mechanical ventilation and acute respiratory distress syndrome in older patients. Clinics In Chest Medicine 2007, 28: 783-91, vii PubMed ID: 17967294, DOI: 10.1016/j.ccm.2007.08.008.
• Liberation from mechanical ventilation: what monitoring matters?Siner JM, Manthous CA. Liberation from mechanical ventilation: what monitoring matters? Critical Care Clinics 2007, 23: 613-38 PubMed ID: 17900486, DOI: 10.1016/j.ccc.2007.05.005.
• VEGF-induced heme oxygenase-1 confers cytoprotection from lethal hyperoxia in vivo.Siner JM, Jiang G, Cohen ZI, Shan P, Zhang X, Lee CG, Elias JA, Lee PJ. VEGF-induced heme oxygenase-1 confers cytoprotection from lethal hyperoxia in vivo. FASEB Journal : Official Publication Of The Federation Of American Societies For Experimental Biology 2007, 21: 1422-32 PubMed ID: 17264168, DOI: 10.1096/fj.06-6661com.
• Cloning of an aquaporin homologue present in water channel containing endosomes of toad urinary bladder.Siner J, Paredes A, Hosselet C, Hammond T, Strange K, Harris HW. Cloning of an aquaporin homologue present in water channel containing endosomes of toad urinary bladder. The American Journal Of Physiology 1996, 270: C372-81 PubMed ID: 8772465, DOI: 10.1152/ajpcell.1996.270.1.C372.