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Jonathan Puchalski, MD, MEd

Associate Professor of Internal Medicine (Pulmonary, Critical Care and Sleep Medicine); Director, Interventional Pulmonology; Director, Interventional Pulmonology, Pulmonary, Critical Care & Sleep Medicine

Research Summary

My research focuses on improving the diagnostic yield of bronchoscopic and pleural procedures, as well as the safety of these procedures. I have an extensive list of publications, including those advocating new techniques we have developed in our interventional pulmonary program.

Extensive Research Description

Our research program focuses on many aspects of lung disease. Our current projects include:

-- Use of a technique that makes a small incision in the airway to provide access to mediastinal and hilar lymph nodes. This allows larger biopsies of lymphadenopathy to help with the diagnosis of lymphoma, sarcoidosis, and others. My current studies include use of this to evaluate isolated mediastinal lymphadenopathy and patients with lung cancer that have adenopathy and might be candidates for treatment with immunotherapy.

-- Analysis of the safety of thoracentesis, chest tube placement and tunneled pleural catheter (pleurx) placement in patients who take anti-coagulant medications.

-- A multi-center study evaluating urokinase in complicated infectious pleural effusions

-- A multi-center study evaluating GM-CSF in the treatment of pulmonary alveolar proteinosis


Research Interests

Bronchial Fistula; Bronchial Neoplasms; Bronchoscopy; Carcinoma, Bronchogenic; Chylothorax; Hemoptysis; Pleural Effusion; Pneumothorax; Pulmonary Alveolar Proteinosis; Pleural Effusion, Malignant; Thoracentesis

Selected Publications